18 completed, 9 unknown, 3 active not recruiting, 3 recruiting. 11 Not applicable, 8 Phase 2, 7 Phase 4, 4 Early Phase 1, 3 Phase 1.
Follow Neomycin: new trials by email Literature Review of Neomycin trials Research Report on Neomycin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Gut Decolonisation With Neomycin/Metronidazole or Rifaximin Before Colon Surgery Rifaximin (Xifaxan), Metronidazole, Neomycin Sulfate - Surgical Site Infection, Colon Surgery | Phase 4 | Not yet recruiting | Universität Luzern | 458 | 2026-06-01 | 2025-09-18 |
| Intestinal Microbiota Transplantation in Patients With Chronic Heart Failure MTP-101-C encapsulated Microbiota, Vancomycin, Neomycin - Chronic Heart Failure | Phase 1 | Recruiting | Melana Yuzefpolskaya, MD | 40 | 2025-10-20 | 2026-10-08 |
| Evaluation of Microbiota Transplant Therapy in Patients With Alopecia Areata Vancomycin, Neomycin and MTT capsules, Placebo capsules - Alopecia Areata, Alopecia Totalis | Phase 2 | Recruiting | University of Minnesota | 40 | 2025-08-21 | 2026-06-26 |
| The Safety and Microbial Changes in the Use of Intranasal Neosporin® Intranasal application of Polymyxin B Sulfate 500,000 IU, Bacitracin zinc 40,000 IU, Neomycin Sulfate 0.35g neomycin base - Teste the Safety of (Polymyxin B Sulfate 500,000 IU, Bacitracin Zinc 40,000 IU, Neomycin Sulfate 0.35g Neomycin Base) Intranasally | Not applicable | Completed | Hospital Universitario Dr. Jose E. Gonzalez | 12 | 2025-02-13 | 2026-07-14 |
| Do Topical Antibiotics Improve Skin Graft Results? Neomycin - Skin Transplantation, Wounds and Injuries | Completed | LAMB Project | 142 | 2024-12-01 | 2025-12-16 | |
| Antibiotics and Vaccine Immune Responses Study BCG vaccine, Yellow Fever vaccine, Vancomycin Oral Capsule - Vaccine Response Impaired | Phase 4 | Recruiting | South Australian Health and Medical Research Institute | 348 | 2023-11-23 | 2026-09-17 |
| SURGIcal COmplication and MIcrobiome ChangeS in Colorectal Surgery Neomycin Sulfate - Anastomotic Leak, Microbial Colonization | Unknown | Uzsoki Hospital | 100 | 2023-02-01 | 2023-03-22 | |
| Safety and Efficacy of DSM 32444 Postbiotic in the Treatment of Acute Rhinosinusitis Neomycin/ Dexameythasone/Xylometazoline, Bacillus subtilis DSM32444 - Rhinosinusitis, Rhinitis | Not applicable | Completed | Huro Biotech Joint Stock Company | 60 | 2022-12-29 | 2024-03-05 |
| Decolonization of Carbapenem-resistant Enterobacterales (CRE) in Patients With Faecal Carriage of CRE With Neomycin Neomycin - Colonization, Asymptomatic | Phase 4 | Unknown | Mahidol University | 60 | 2022-11-24 | 2022-11-30 |
| Bowel Preparation in Elective Pediatric Colorectal Surgery Senna, Sodium Picosulfate, Magnesium Oxide and Citric Acid, Metronidazole Oral - Colostomy, Hirschsprung Disease - Pull Through | Not applicable | Unknown | McMaster University | 81 | 2022-01-01 | 2021-12-09 |
| Fecal Microbiota Transplant and Re-introduction of Anti-PD-1 Therapy (Pembrolizumab or Nivolumab) for the Treatment of Metastatic Colorectal Cancer in Anti-PD-1 Non-responders Biopsy, Fecal Microbiota Transplantation, Fecal Microbiota Transplantation Capsule - Metastatic Colorectal Adenocarcinoma, Metastatic Small Intestinal Adenocarcinoma | Phase 2 | Active not recruiting | M.D. Anderson Cancer Center | 15 | 2021-02-22 | 2026-06-12 |
| Prophylatic Effect Preoperative Antibiotics With Mechanical Bowel Preparation in SSIs Neomycin,metronidazole - Surgical Site Infection, Postoperative Complications | Not applicable | Completed | Third Affiliated Hospital, Sun Yat-Sen University | 309 | 2019-01-17 | 2023-04-05 |
| Comparing No Mechanical Bowel Preparation With Oral Antibiotics Alone in Patients Undergoing Elective Colon Surgery No Preparation, Neomycin and Flagyl - Elective Colon Surgery | Phase 4 | Active not recruiting | Ottawa Hospital Research Institute | 630 | 2018-10-23 | 2026-06-16 |
| Pilot Study of Fundamental Modification of the Gut Microbiota in the Treatment of Refractory Crohn's Disease Vancomycin, Neomycin, Ciprofloxacin - Crohn Disease | Phase 2 | Completed | Children's Hospital of Philadelphia | 10 | 2018-07-12 | 2022-02-09 |
| Responses to Rabies Vaccine in Adults With or Without Antibiotics Rabies Vaccine, Metronidazole, Vancomycin - Rabies Human | Phase 4 | Completed | Emory University | 37 | 2018-07-05 | 2023-06-08 |
| Serial Endoscopic Surveillance & Direct Topical Antibiotics to Define the Role of Microbes in Anastomotic Healing Cipro, metronidazole, neomycin combo, Serial Endoscopic Surveillance, Saline - Anastomotic Leak, Rectal Cancer | Phase 2 | Withdrawn | University of Chicago | 2017-03-03 | 2023-04-26 | |
| Optimal Fecal Microbiota Transplant Dosing for Mild to Moderate Ulcerative Colitis Fecal Microbiota Transplantation (FMT), OpenBiome, pretreatment antibiotics - Ulcerative Colitis | Phase 1 | Completed | Najwa Elnachef | 30 | 2017-03-02 | 2021-04-28 |
| Neomycin and Metronidazole Hydrochloride With or Without Polyethylene Glycol in Reducing Infection in Patients Undergoing Elective Colorectal Surgery Polyethylene Glycol, Neomycin, Metronidazole Hydrochloride - Colorectal Neoplasms, Diverticulitis | Early Phase 1 | Unknown | Thomas Jefferson University | 224 | 2016-09-01 | 2018-08-22 |
| Fundamental Modification of the Gut Microbiota in the Treatment of Refractory Crohn's Disease Fluconazole, Vancomycin, Neomycin - Crohn's Disease | Phase 2 | Completed | University of Pennsylvania | 8 | 2016-08-01 | 2024-02-06 |
| Interventional Bioremediation of Microbiota in Metabolic Syndrome Vancomycin, Placebo, Neomycin - Pre-Diabetes | Phase 2 | Terminated | University of Minnesota | 12 | 2016-06-01 | 2023-02-22 |
Showing 20 of 37. Sign in to see all of them.
Surgical Wound Infection (5) · Colorectal Neoplasms (3) · Anastomotic Leak (2) · Colitis, Ulcerative (2) · Crohn Disease (2) · Diabetes Mellitus (2) · Inflammatory Bowel Diseases (2) · Alopecia Areata (1) · Alopecia universalis (1) · Asymptomatic Infections (1) · Bacteremia (1) · Biliary Atresia (1) · Blind Loop Syndrome (1) · Cholangitis (1) · Communicable Diseases (1)
Emory University (2) · University of Minnesota (2) · Bayer (1) · Cedars-Sinai Medical Center (1) · Children's Hospital of Philadelphia (1) · Chulalongkorn University (1) · Helsinki University Central Hospital (1) · Hospital Universitario Dr. Jose E. Gonzalez (1) · Huro Biotech Joint Stock Company (1) · Julio Ramirez (1) · LAMB Project (1) · Laboratoire Innotech International (1) · M.D. Anderson Cancer Center (1) · Mahidol University (1) · Maimónides Biomedical Research Institute of Córdoba (1)
United States (15) · Israel (2) · Switzerland (2) · Thailand (2) · Australia (1) · Bangladesh (1) · Brazil (1) · Canada (1) · China (1) · Finland (1) · France (1) · Germany (1) · Hungary (1) · Mexico (1) · Netherlands (1)
Lindsey Albenberg, DO (2) · Nadine Rouphael, MD (2) · Adhiratha Boonyasiri, MD (1) · Adrian Camacho Ortiz, MD, PhD (1) · Alexander Khoruts, MD (1) · Benjamin Phillips, MD (1) · Carlos A Caramori (1) · David Lynn (1) · David Seligson, MD (1) · Fernando G Romeiro (1) · George T Macfarlane, BSCc, PHD (1) · Hongbo Wei, Ph.D (1) · James D Lewis, MD, MSCE (1) · Jean Marc Bohbot (1)
PMID 36748942, PMID 15276398, PMID 15840453, PMID 19588358, PMID 22530208, PMID 25534776, PMID 27494911, PMID 30530985, PMID 30616014, PMID 31402112, PMID 31954100, PMID 34174187, PMID 35365713, PMID 37702427, PMID 38796500, PMID 4902833, PMID 8948280
2014 (1), 2025 (1), K23DK109136 (1), P50CA221707 (1)