9 recruiting, 6 completed, 5 not yet recruiting, 3 enrolling by invitation. 10 Not applicable, 3 Phase 4, 2 Phase 3, 1 Early Phase 1, 1 Phase 2.
Follow Hemorrhoid: new trials by email Literature Review of Hemorrhoid trials Research Report on Hemorrhoid
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Laser Hemorrhoidoplasty Versus Open Hemorrhoidectomy for Postoperative Pain Open Milligan-Morgan Hemorrhoidectomy, Laser Hemorrhoidoplasty - Hemorrhoid | Not applicable | Not yet recruiting | Allied Hospital Faisalabad | 68 | 2026-11-01 | 2026-09-29 |
| Bleeding Reduction in Grade II-III Haemorrhoids Through Embolization Treatment Haemorrhoid artery embolizsation (HAE) - Hemorrhoid, Hemorrhoid Bleeding | Not yet recruiting | Cardiovascular and Interventional Radiological Society of Europe | 250 | 2026-11-01 | 2026-10-21 | |
| Cryotherapy for Post-Hemorrhoidectomy Pain Milligan-Morgan Hemorrhoidectomy with Cryotherapy, Miligan-Morgan haemorroidectomy - Hemorrhoid, Hemorrhoidectomy | Not applicable | Not yet recruiting | Cairo University | 114 | 2026-08-04 | 2026-07-22 |
| Case-Specific Health Care Professional Clinical Survey for Concerto Versa™ Detachable Coils Concerto Versa™ Detachable Coils - Arteriovenous Malformation, Gastrointestinal Bleed | Enrolling by invitation | Medtronic Endovascular | 30 | 2026-07-24 | 2026-10-15 | |
| Nimsai Herbal for Grade 2-3 Hemorrhoids: A Quadruple-Blind Placebo-Controlled Mechanistic Trial Nimsai Herbal, Placebo - Hemorrhoid, Hemorrhoidal Disease | Phase 3 | Not yet recruiting | Nimsai Academia | 50 | 2026-06-22 | 2026-06-25 |
| SHAPE Versus Milligan-Morgan Hemorrhoidectomy for Hemorrhoidal Disease Skin Sparing Hemorrhoidectomy and PExy (SHAPE), Milligan-Morgan Hemorrhoidectomy - Hemorrhoid | Not applicable | Recruiting | Cairo University | 68 | 2026-05-24 | 2026-05-20 |
| Prospective HemorrhoIdaL EmboliSation (PILES) Registry Hemorrhoid Artery Embolization - Hemorrhoid, Internal Hemorrhoids | Recruiting | Joint & Vascular Institute | 1200 | 2026-01-18 | 2026-06-12 | |
| Definition and Validation of HeQAS for the Assessment of Technical Quality in Excisional Hemorrhoidectomy Hemorrhoidectomy, Hemorrhoid | Active not recruiting | Hospital Son Llatzer | 80 | 2026-01-01 | 2026-07-22 | |
| Topical Nifedipine 0.3% Plus Lidocaine 1.5% for Uncomplicated Hemorrhoidal Disease topical nifedipine 0.3% plus lidocaine 1.5% - Hemorrhoid Bleeding, Hemorrhoids Prolapse | Recruiting | Cardarelli Hospital | 80 | 2025-09-02 | 2025-12-22 | |
| "Lignocaine vs GTN Ointment for Postoperative Pain After Hemorrhoidectomy") Lignocaine Ointment, Glyceryl Trinitrate Ointment 0.2% - Hemorrhoid, Postoperative Pain | Not applicable | Recruiting | King Edward Medical University | 64 | 2025-08-02 | 2025-09-08 |
| Efficacy and Safety Evaluation of Ruscus Aculeatus L in Patients With Hemorrhoids Neoven 225 mg capsules, Placebo - Hemorrhoid | Phase 4 | Recruiting | Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey | 250 | 2025-08-01 | 2025-08-19 |
| Comparison of Outcome of Injection Sclerotherapy Versus Rubber Band Ligation for Second Degree Hemorrhoids Injection Sclerotherapy, Rubber Band Ligation - Hemorrhoid | Not applicable | Completed | Gulab Devi Hospital | 128 | 2025-07-07 | 2026-06-09 |
| ORal Aminaphtone and Combined LidocainE Hemorrhoid | Recruiting | Treviso Regional Hospital | 50 | 2025-05-08 | 2025-06-18 | |
| Cough and Hemorrhoids Hemorrhoid, Cough | Recruiting | Muğla Sıtkı Koçman University | 134 | 2025-03-14 | 2025-05-11 | |
| Effect of Listening to Standardized Music Sequences on Preventing Postoperative Pain in Proctologic Surgery Standardized Music Listening Therapy - Hemorrhoid, Anal Fistulas | Not applicable | Recruiting | Clinique Saint-Vincent | 550 | 2025-02-03 | 2025-06-26 |
| Endoscopic Rubber Band Ligation and Milligan-Morgan Hemorrhoidectomy for the Treatment of Grade II-III Internal Hemorrhoids: a Multicenter, Non-randomized Controlled Study Hemorrhoid | Active not recruiting | Weidong Tong | 548 | 2025-01-01 | 2025-01-27 | |
| HEmorrhoidAl Disease in Inflammatory Bowel Disease: a Multicenter Prospective Cohort Study IBD (Inflammatory Bowel Disease), Hemorrhoid | Not yet recruiting | Treviso Regional Hospital | 50 | 2025-01-01 | 2024-10-15 | |
| The Efficacy of Aescin in Combination With Micronized Purified Flavonoid Fraction (MPFF) in the Control of Bleeding and Prevent Recurrence of Acute Internal Hemorrhoids, A Randomized Controlled Trial, A Pilot Study Aescin in Horse Chestnut, MPFF - Hemorrhoid | Early Phase 1 | Enrolling by invitation | Chiang Mai University | 120 | 2024-12-20 | 2024-12-24 |
| Data-driven Clustering in Hemorrhoid Surgery: Retrospective Monocentric Study for the Identification of Clinical Phenotypes Any surgical procedure for hemorrhoidal disease - Hemorrhoid, Hemorrhoid Prolapse | Enrolling by invitation | IRCCS Policlinico S. Donato | 100 | 2024-12-01 | 2026-08-27 | |
| Trial of Latex vs Non-latex Hemorrhoid Banding Latex Band, Non-Latex Band - Hemorrhoid, Hemorrhoid Bleeding | Not applicable | Recruiting | Huntington Memorial Hospital | 164 | 2024-08-30 | 2026-09-17 |
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Hemorrhoids (27) · Pain, Postoperative (5) · Agnosia (2) · Hemorrhage (2) · Arteriovenous Malformations (1) · Cough (1) · Esophageal and Gastric Varices (1) · Fissure in Ano (1) · Fistula (1) · Gastrointestinal Hemorrhage (1) · Inflammatory Bowel Diseases (1) · Lymphoma, Follicular (1) · Peripheral Arterial Disease (1) · Peripheral Vascular Diseases (1) · Rectal Fistula (1)
Cardiovascular Diseases (27) · Digestive System Diseases (27) · Gastrointestinal Diseases (27) · Intestinal Diseases (27) · Rectal Diseases (27) · Vascular Diseases (26) · Pathological Conditions, Signs and Symptoms (9) · Pathologic Processes (7) · Signs and Symptoms (7) · Neurologic Manifestations (6) · Pain (5) · Postoperative Complications (5) · Nervous System Diseases (2) · Neurobehavioral Manifestations (2) · Perceptual Disorders (2)
Bupivacaine (3) · Anesthesia, Local (1) · Anesthesia, Spinal (1) · Cryotherapy (1) · Epinephrine (1) · Escin (1) · Nifedipine (1) · Prilocaine (1) · Saline Solution (1) · Sodium Chloride (1) · horse chestnut seed (1)
Cairo University (2) · Treviso Regional Hospital (2) · Allied Hospital Faisalabad (1) · Cardarelli Hospital (1) · Cardiovascular and Interventional Radiological Society of Europe (1) · Chiang Mai University (1) · Clinique Saint-Vincent (1) · Diskapi Teaching and Research Hospital (1) · Federal University of São Paulo (1) · Gulab Devi Hospital (1) · Hospital Son Llatzer (1) · Huntington Memorial Hospital (1) · IRCCS Policlinico S. Donato (1) · Joint & Vascular Institute (1) · King Edward Medical University (1)
United States (5) · Turkey (Türkiye) (4) · Italy (3) · China (2) · Egypt (2) · Pakistan (2) · Brazil (1) · Poland (1) · Reunion (1) · Spain (1) · Thailand (1)
Adam Truong, MD (1) · Ali Shariat, MD (1) · Christoph A. Binkert, Prof. Dr. med. (1) · Clare Bent, Dr (1) · Hafiz Ahmad Rauf (1) · Haitham M. Azmy Basiouny, MD (1) · John R Laird, Jr, MD (1) · Kyu Joo Park, MD, PhD (1) · Mingkai Chen, M.D (1) · Mostafa Sedky, MD (1) · Muhammad Faisal Bilal Lodhi, MBBS, FCPS General Surgery (1) · Rioko K Sakata, PhD (1) · Roberto Iezzi, Prof. (1) · Sang Lee, M.D. (1)
PMID 30451751, PMID 10458123, PMID 11289288, PMID 1174785, PMID 12432293, PMID 15399351, PMID 22900785, PMID 2295392, PMID 22980596, PMID 26327134, PMID 26547759, PMID 27209079, PMID 29420423, PMID 30998519, PMID 31057696, PMID 32067353, PMID 34530908, PMID 39228195, PMID 39757160, PMID 42392851