49 completed, 7 unknown, 2 active not recruiting, 1 not yet recruiting. 23 Not applicable, 18 Phase 4, 9 Phase 1, 4 Phase 2, 4 Phase 3.
Follow Prilocaine: new trials by email Literature Review of Prilocaine trials Research Report on Prilocaine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Spinal Anesthesia With Bupivacaine Versus Prilocaine on Postoperative Shivering After Inguinal Hernia Repair Bupivacaine Spinal Anesthesia, Prilocaine spinal anesthesia, Spinal Anesthesia (bupivacaine) spinal anesthsia (prilocaine) - Postoperative Shivering | Phase 4 | Not yet recruiting | Amr mohamed | 80 | 2026-05-01 | 2026-05-04 |
| Intraprostatic Anesthesia During Transperineal Prostate Biopsy Prilocaine, Bupivacaine, Perineal Local Anesthesia - Prostate Cancer (Diagnosis), Prostate-Specific Antigen | Not applicable | Active not recruiting | Marmara University | 50 | 2025-11-01 | 2026-07-06 |
| Silicone Band Versus Prilocaine Spray for Lifelong Premature Ejaculation Frenular Silicone Band, Prilocaine 10% Spray - Premature Ejaculation | Not applicable | Completed | Başakşehir Çam & Sakura City Hospital | 32 | 2025-09-15 | 2026-09-15 |
| Unilateral Intrathecal Bupivacaine Versus Prilocaine on Postoperative Spontaneous Voiding Prilocaine, Bupivacain - Fast Track Surgery | Phase 4 | Completed | Theodor Bilharz Research Institute | 70 | 2024-08-03 | 2025-12-03 |
| Comparison of the Short-term Clinical Effects of Anterior Extra-articular and Posterior Intra-articular Administration of Ultrasound-guided Steroid Injection in the Treatment of Adhesive Capsulitis. A combination of 1 mL of triamcinolone acetonide (40 mg/mL) and 1 mL of prilocaine hydrochloride (2%) - Adhesive Capsulitis of the Shoulder | Not applicable | Unknown | Kartal City Hospital | 50 | 2024-05-24 | 2024-03-06 |
| Hyperbaric Bupivacaine Versus Hyperbaric Prilocaine in Spinal Anaesthesia prilocaine, Bupivacaine - Knee Replacement, Total, Knee Replacement Surgery | Phase 4 | Active not recruiting | National University Hospital, Singapore | 50 | 2024-05-17 | 2026-01-09 |
| Low Dose Bupivacaine Versus Prilocaine Regarding Hemodynamic Stability and Safety in Geriatrics Bupivacain - Recruitment | Phase 1 / Phase 2 | Completed | Fayoum University Hospital | 100 | 2024-04-23 | 2025-03-11 |
| Comparing the Effect of Spinal Bupivacaine Versus Spinal Prilocaine on Maternal Blood Pressure in Cesarean Section Bupivacaine, Prilocaine - Spinal Anesthetics Causing Adverse Effects in Therapeutic Use | Not applicable | Completed | South Valley University | 120 | 2024-04-21 | 2025-03-19 |
| Intrathecal Injection of Hyperbaric Prilocaine Versus Hyperbaric Bupivacaine for Cystoscopic Procedures Bupivacaine, Prilocaine - Intrathecal Injection, Hyperbaric Prilocaine | Not applicable | Completed | Helwan University | 100 | 2024-04-01 | 2026-06-24 |
| Effect of Prilocaine vs Bupivacaine on Hemodynamics in Spinal Anesthesia for Geriatric Patients Prilocaine, Bupivacaine - Hemodynamic Instability | Phase 3 | Completed | Cairo University | 112 | 2023-12-20 | 2025-07-02 |
| Effect of Prilocaine on Motor Block During Caesarean Section prilocaine, bupivacaine - Spinal for Caesarean Section | Phase 4 | Completed | Cairo University | 40 | 2023-12-01 | 2024-02-28 |
| Comparison of Infraclavicular Brachial Plexus Block and Local Anesthesia in Arteriovenous Fistula Surgeries and Their Effects on Tissue Oxygen Saturation NIRS, Pinprick Test, Modified Bromage Scale - Renal Disease, Chronic | Not applicable | Completed | Ankara City Hospital Bilkent | 60 | 2023-10-22 | 2025-01-10 |
| Selective Spinal Anaesthesia With Hyperbaric Prilocain With 2%Provides Better Perioperative Hemodynamic Stability for Patients With Peripheral Vascular Disease and Cardiac Dysfunction in Lower Limb Surgery Bupivacaine 0.5% Injectable Solution, Prilocaine Hydrochloride 2% Injection - Hemodynamic Stability | Not applicable | Unknown | Assiut University | 80 | 2023-10-01 | 2023-05-26 |
| Comparison of Different Local Anesthetics in Cervical Facet Medial Branch Blockade facet median block with prilocain, facet median block with lidocaine - Pain, Neck | Not applicable | Completed | Ankara University | 114 | 2023-10-01 | 2024-02-06 |
| Understanding Rebound Pain After Regional Anesthesia Resolution in Healthy Volunteers Mepivacaine - Regional Anesthesia Morbidity, Pain, Acute | Phase 1 | Completed | Brigham and Women's Hospital | 40 | 2023-09-28 | 2025-11-05 |
| Investigation of the Effect of Central Sensitization (CS) on Steroid Injection Response in Rotator Cuff Lesion Injection of 1 CC Betamethasone Dipropionate + Betamethasone Sodium Phosphate (Diprospan) and 4 cc 2% Prilocaine (Priloc)mixture into the subacromial space - Central Sensitisation, Subacromial Impingement Syndrome | Not applicable | Completed | Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey | 44 | 2023-06-02 | 2025-09-12 |
| Genicular Nerve Block in Chronic Knee Osteoarthritis Genicular nerve block with prilocaine, genicular nerve block with prilocaine and triamcinolone, Sham injection - Gonarthrosis; Primary, Genicular Nerve Block | Not applicable | Completed | Haydarpasa Numune Training and Research Hospital | 81 | 2023-04-01 | 2025-11-28 |
| Efficacy of Topical Lidocaine/Prilocaine in Pain Management in Pleurocentesis lidocaine 2.5% and prilocaine 2.5% cream in pain management before pleurocentesis. - Pleural Effusion | Phase 4 | Unknown | Assiut University | 118 | 2023-01-01 | 2023-08-09 |
| Combined Adductor&Sciatic Nerve Block vs Femoral&Sciatic Nerve Block in Total Knee Replacement Surgery Combine Adductor Canal & Sciatic Nerve Block, Combine Femoral & Sciatic Nerve Block, Bupivacaine and prilocaine hydrochloride - Orthopedic Disorder, Total Knee Replacement | Not applicable | Completed | Bakirkoy Dr. Sadi Konuk Research and Training Hospital | 68 | 2022-11-14 | 2025-06-08 |
| Simultaneous Versus Sequential Fractional CO2 Laser and Subcision Combination for Post-acne Atrophic Scars: A Split-face Comparative Study. Simultaneous combination of fractional CO2 laser and subcision, Sequential combination of fractional CO2 laser and subcision, Fractional CO2 laser - Atrophic Acne Scar | Not applicable | Completed | Ho Chi Minh City Hospital of Dermato-Venereology | 34 | 2022-10-24 | 2023-10-04 |
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Pain (5) · Keratosis, Actinic (4) · Pain, Postoperative (3) · Acute Pain (2) · Agnosia (2) · Premature Ejaculation (2) · Acquired Immunodeficiency Syndrome (1) · Acute Kidney Injury (1) · Arthritis (1) · Bursitis (1) · Cicatrix (1) · Common Cold (1) · Compartment Syndromes (1) · Disease (1) · Gout (1)
Dong-A University (4) · Assiut University (2) · Bozyaka Training and Research Hospital (2) · Brigham and Women's Hospital (2) · Cairo University (2) · Joanneum Research Forschungsgesellschaft mbH (2) · Netherlands Institute for Pigment Disorders (2) · ASST Gaetano Pini-CTO (1) · AZ St.-Dimpna Geel (1) · Amr mohamed (1) · Ankara City Hospital Bilkent (1) · Ankara University (1) · Bakirkoy Dr. Sadi Konuk Research and Training Hospital (1) · Başakşehir Çam & Sakura City Hospital (1) · Beatrice Olsson Duse (1)
Turkey (Türkiye) (11) · United States (10) · Egypt (8) · Brazil (3) · South Korea (3) · Austria (2) · Belgium (2) · France (2) · Italy (2) · Netherlands (2) · Canada (1) · Denmark (1) · Germany (1) · Indonesia (1) · Kenya (1)
Albert Wolkerstorfer, MD, PhD (2) · Menno A. De Rie, MD, PhD (2) · Thomas Pieber, Prof. (2) · Ben Gys, md (1) · Culley Carson, MD (1) · Desire Onwochei, MBBS (1) · Dr. Anthony Albers, MDCM, FRCSC (1) · Eberhard Kochs, MD (1) · Ekram Abdullah, Professor (1) · Elika Hoss (1) · Emre Ata, Asst.Prof (1) · Eneida de Paula, PhD (1) · Georg Rehmert, Dr. med. (1)
PMID 20355262, PMID 20529983, PMID 20961685, PMID 21203878, PMID 22182397, PMID 23176984, PMID 23320599, PMID 23619203, PMID 25211156, PMID 25523242, PMID 31412032, PMID 32442198, PMID 33123644, PMID 33212328, PMID 33399396, PMID 35858717, PMID 42359695, PMID 42402656, PMID 42777886
2018 (1), 2019 (1), 2023 (1)