30 completed, 17 unknown, 7 recruiting, 4 withdrawn. 27 Not applicable, 10 Phase 4, 8 Phase 2, 6 Phase 1, 6 Phase 3.
Follow this condition Literature Review of Fissure in Ano trials Research Report on Fissure in Ano
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| GLP-1 Receptor Agonists and Early Proctologic Effects in Morbid Obesity GLP-1 receptor agonist therapy - Morbid Obesity, Anorectal Diseases | Not yet recruiting | Gazi University | 100 | 2026-08-01 | 2026-06-25 | |
| AI-Assisted Written Information in Chronic Anal Fissure AI-assisted written patient information, Standardized verbal counseling - Chronic Anal Fissure | Not applicable | Recruiting | Sanliurfa Education and Research Hospital | 220 | 2026-07-15 | 2026-09-09 |
| Topical Nitroglycerin Versus Lateral Internal Sphincterotomy for Chronic Anal Fissure Topical 0.2% Glyceryl Trinitrate (Nitroglycerin) Ointment, Lateral Internal Sphincterotomy - Chronic Anal Fissure | Not applicable | Completed | Sheikh Zayed Federal Postgraduate Medical Institute | 72 | 2026-06-15 | 2026-10-21 |
| The Impact of Perianal Disease on Patient's Sex Life Patient Reported Outcome Assessment (Questionnaires) - Perianal Crohn Disease, Perianal Fistula | Recruiting | AHEPA University Hospital | 60 | 2026-03-31 | 2026-04-09 | |
| Effect of Listening to Standardized Music Sequences on Preventing Postoperative Pain in Proctologic Surgery Standardized Music Listening Therapy - Hemorrhoid, Anal Fistulas | Not applicable | Recruiting | Clinique Saint-Vincent | 550 | 2025-02-03 | 2025-06-26 |
| Effect of Enhanced Recovery After Surgery for Benign Anorectal Conditions Enhanced recovery after surgery protocol, Routine pathway - Anal Fistula, Anal Fissure Chronic | Not applicable | Recruiting | Mansoura University | 100 | 2024-12-17 | 2025-02-03 |
| Ultrasound Assessment After Surgery for Chronic Anal Fissure Anal Fissure Chronic | Recruiting | Hospital Clínico Universitario de Valencia | 66 | 2024-10-12 | 2026-09-17 | |
| Percutaneous Tibial Nerve Stimulation (PTNS) for the Treatment of Chronic Anal Fissure PTNS - Fissure in Ano | Not applicable | Not yet recruiting | Region Skane | 52 | 2024-10-01 | 2024-03-01 |
| Could Preoperative Assessment of Physical and Psychological Status Help Predict Pain After Anorectal Surgery? Hemorrhoids, Anal Fistula | Unknown | Center of Endourology "Endocenter" | 200 | 2024-01-08 | 2023-10-06 | |
| Laser Versus Surgery in Anal Diseases in Inflammatory Bowel Patients treatment of anal diseases in inflammatory bowel patients, Laser, traditional surgery - Inflammatory Bowel Diseases, Anal Fissure | Not applicable | Completed | Zagazig University | 108 | 2023-09-05 | 2024-05-14 |
| Combined Method of Surgical Treatment of Anal Fissure excision of the anal fissure with further relaxation of the internal sphincter with botulinum toxin A - Chronic Anal Fissure | Not applicable | Recruiting | State Scientific Centre of Coloproctology, Russian Federation | 122 | 2023-09-01 | 2025-12-05 |
| Pudendal Nerve Block With Bupivacaine Alone and Bupivacaine With Methylene Blue for Postoperative Analgesia Ultrasound guided Pudendal nerve block - Hemorrhoids, Anal Fissure and Fistula | Not applicable | Unknown | Nepal Mediciti Hospital | 60 | 2023-08-12 | 2023-11-09 |
| Regenerative Therapy With Autologous Stromal Vascular Fraction Derived Mesenchymal Stem Cells and Platelet-rich Plasma to Treat Complex Perianal Diseases Regenerative therapy with SVF-PRP to supplement perianal surgery - Perianal Fistula, Perianal Crohn Disease | Unknown | Kantonsspital Winterthur KSW | 50 | 2023-01-25 | 2023-02-02 | |
| Comparison of Injections of Botulinum Toxin and Topical Nitroglycerin Ointment for the Treatment of Chronic Anal Fissure Botulinum injection, GTN OINTMENT - Fissure in Ano | Not applicable | Unknown | Pak Emirates Military Hospital | 90 | 2022-11-01 | 2023-03-29 |
| Microbiota in Chronic Anal Fissure and Its Association With Prognosis Anal Fissure, Microbial Colonization | Unknown | Lasse Krogsbøll | 80 | 2022-09-01 | 2022-06-06 | |
| Botulinum Toxin Type A in the Treatment of Chronic Anal Fissure Botulinum toxin type A - Chronic Anal Fissure | Not applicable | Unknown | State Scientific Centre of Coloproctology, Russian Federation | 140 | 2022-09-01 | 2022-10-28 |
| Efficacy of Polyethylene Glycol vs Lactulose With Isabgol in Acute Fissure-in-Ano: PEGASIS Trial Polyethylene Glycol, Isabgol + Lactulose - Anal Fissure, Constipation | Phase 2 / Phase 3 | Completed | All India Institute of Medical Sciences, Bhubaneswar | 144 | 2022-05-27 | 2023-07-25 |
| Use of Fototherapy in the Treatment of Fissure in Ano Fototherapy - Fissure in Ano | Not applicable | Completed | Centro de Atenção ao Assoalho Pélvico | 10 | 2022-03-01 | 2023-08-15 |
| Efficacy and Safety of CONAN® Proctological Cream for Treatment of Haemorrhoidal Disease CONAN® Proctological Cream - Hemorrhoid Pain, Haemorrhoid Inflammation | Not applicable | Completed | Omikron Italia S.r.l. | 40 | 2022-03-01 | 2024-04-03 |
| Comparative Analysis of Hypobaric Versus Hyperbaric Bupivacaine for Spinal Anesthesia in Day-Case Anorectal Surgery use of different spinal anesthesia techniques - Anorectal Diseases, Hemorrhoids | Completed | Ankara City Hospital Bilkent | 80 | 2022-02-01 | 2024-07-23 |
Showing 20 of 62. Sign in to see all of them.
Hemorrhoids (20) · Rectal Fistula (10) · Constipation (3) · Fecal Incontinence (3) · Fistula (3) · Pain (3) · Pain, Postoperative (3) · Rectal Diseases (3) · Agnosia (2) · Diarrhea (2) · Inflammatory Bowel Diseases (2) · Pilonidal Sinus (2) · Anemia (1) · Breast Diseases (1)
Anus Diseases (62) · Digestive System Diseases (62) · Gastrointestinal Diseases (62) · Intestinal Diseases (62) · Rectal Diseases (59) · Pathological Conditions, Signs and Symptoms (23) · Cardiovascular Diseases (20) · Vascular Diseases (20) · Signs and Symptoms (13) · Pathological Conditions, Anatomical (12) · Digestive System Fistula (11) · Intestinal Fistula (11) · Fistula (9) · Neurologic Manifestations (8) · Pathologic Processes (7)
Botulinum Toxins, Type A (5) · Nitroglycerin (5) · Diltiazem (3) · Lateral Internal Sphincterotomy (3) · Lidocaine (3) · Lactulose (2) · Ointments (2) · Polyethylene Glycols (2) · isosorbide-5-mononitrate (2) · Acetaminophen (1) · Anti-Inflammatory Agents (1) · Calcium Dobesilate (1) · Centella asiatica extract (1) · Dexamethasone (1) · Diclofenac (1)
Mansoura University (7) · State Scientific Centre of Coloproctology, Russian Federation (3) · Biolab Sanus Farmaceutica (2) · Forest Laboratories (2) · RDD Pharma Ltd (2) · SB Istanbul Education and Research Hospital (2) · AHEPA University Hospital (1) · Al-Kindy College of Medicine (1) · All India Institute of Medical Sciences, Bhubaneswar (1) · American University of Beirut Medical Center (1) · Ankara City Hospital Bilkent (1) · Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (1) · Center of Endourology "Endocenter" (1) · Centro de Atenção ao Assoalho Pélvico (1) · Clinical Centre of Serbia (1)
Egypt (8) · Turkey (Türkiye) (6) · Italy (4) · Russia (4) · Switzerland (4) · Spain (3) · Israel (2) · Pakistan (2) · United States (2) · Brazil (1) · Canada (1) · China (1) · Colombia (1) · Czechia (1) · Greece (1)
Sergey A. Frolov, Ph.D. (2) · Adriana M Cadavid, MD (1) · Antonio Arroyo, PhD (1) · Antonio Carroccio, Prof. (1) · Ayman Al-Jazaeri (1) · Cem Atabiner (1) · Dan Carter (1) · Daniel C Steinemann, MD (1) · Daniel Steinemann (1) · Dieter Hahnloser, Prof. (1) · Eman Sbaity, MD (1) · Emmanouil Pappou, MD, PhD (1) · Feyzullah Ersoz (1) · Gabriella Giarratano, Medicine (1)
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