7 completed, 3 unknown, 2 withdrawn, 1 terminated. 8 Not applicable, 3 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 8 | Completed 6, Unknown 1, Withdrawn 1 |
| Phase 2 | 3 | Terminated 1, Unknown 1, Withdrawn 1 |
| Phase 1 | 1 | Withdrawn 1 |
Follow Brain Contusion: new trials by email Literature Review of Brain Contusion trials Research Report on Brain Contusion
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Near Infra-red Spectroscopy for Detection of Intracranial Haematoma Near infrared spectroscopy - Traumatic Brain Injury, Intracerebral Hemorrhage | Unknown | Chinese University of Hong Kong | 24 | 2022-04-01 | 2021-07-29 | |
| Near-infrared Spectroscopy (NIRS) for Intracranial Hematoma Detection near-infrared scanner - Traumatic Brain Injury | Not applicable | Completed | National Institute of Mental Health and Neuro Sciences, India | 208 | 2021-08-24 | 2022-03-03 |
| A Study to Evaluate the Efficacy and Safety of BIIB093 in Participants With Brain Contusion BIIB093, Placebo - Brain Contusion | Phase 2 | Terminated | Remedy Pharmaceuticals, Inc. | 92 | 2019-10-06 | 2024-11-27 |
| Brain Injury Therapy of Exercise and Enriched Environment Exercise, Delayed Exercise, Exercise and enrichment - Brain Injuries | Not applicable | Unknown | Wayne State University | 42 | 2016-05-01 | 2020-03-26 |
| Comparative Effectiveness of Family Problem-Solving Therapy (F-PST) for Adolescent TBI Therapist Guided Face to Face Family Problem Solving, Therapist Guided Online Family Problem Solving, Self-Guided Online Family Problem Solving - Tbi, Intracranial Edema | Not applicable | Completed | Children's Hospital Medical Center, Cincinnati | 151 | 2014-11-01 | 2018-01-29 |
| Concussion in Motor Vehicle Accidents: The Concussion Identification Index The Concussion Identification Index, ImPACT - Motor Vehicle Accidents, TBI (Traumatic Brain Injury) | Completed | Clionsky Neuro Systems Inc. | 1790 | 2013-11-01 | 2016-08-08 | |
| Attention Intervention Management AIM - Traumatic Brain Injury (TBI), Attention Deficit Hyperactivity Disorder (ADHD) | Not applicable | Withdrawn | Children's Hospital Medical Center, Cincinnati | 2013-01-01 | 2016-03-08 | |
| Hypernatremia for the Prevention and Treatment of Cerebral Edema in Traumatic Brain Injury Induced, sustained hypernatremia using hypertonic saline, Standard of care (hypertonic saline and mannitol; serum sodium) - Traumatic Brain Injury, Subdural Hematoma | Phase 1 / Phase 2 | Withdrawn | Massachusetts General Hospital | 2012-07-01 | 2016-12-12 | |
| The Effect of Single Dose D-Cycloserine on Cognitive Outcome in Moderate Traumatic Brain Injury (TBI) Patients D-cycloserine, placebo - Traumatic Brain Injury | Phase 2 | Unknown | Hadassah Medical Organization | 100 | 2011-08-01 | 2011-04-28 |
| Rehabilitation Research and Training Center for Traumatic Brain Injury Interventions--Teen Online Problem Solving Study Teen Online Problem Solving (TOPS), Teen Online Problem Solving--Teen Only (TOPS-TO), Internet Resources Comparison (IRC) - Traumatic Brain Injury | Not applicable | Completed | Children's Hospital Medical Center, Cincinnati | 153 | 2010-03-01 | 2016-03-08 |
| Internet-based Interacting Together Everyday, Recovery After Childhood TBI (I-InTERACT)--RRTC Internet-based Interacting Together Everyday: Recovery After Childhood TBI (I-InTERACT), Internet-based-Interacting Together Everyday, Recovery after Childhood TBI Express (I-InTERACT Express), Internet Resources Comparison (IRC) - Traumatic Brain Injury | Not applicable | Completed | Children's Hospital Medical Center, Cincinnati | 117 | 2009-10-01 | 2016-03-08 |
| Interacting Together Everyday: Recovery After Childhood Traumatic Brain Injury (TBI) "I-InTERACT Internet-based Interacting Together Everyday: Recovery After Childhood TBI, Internet Resources Comparison - Traumatic Brain Injury | Not applicable | Completed | Children's Hospital Medical Center, Cincinnati | 41 | 2008-06-01 | 2014-10-28 |
| Internet-Based Treatment for Children With Traumatic Brain Injuries & Their Families: Counselor Assisted Problem Solving Counselor-assisted problem solving (CAPS), Internet-resource comparison (IRC) - Traumatic Brain Injury | Not applicable | Completed | Children's Hospital Medical Center, Cincinnati | 132 | 2007-03-01 | 2014-09-19 |
Brain Injuries, Traumatic (12) · Brain Injuries (8) · Craniocerebral Trauma (8) · Hematoma, Subdural (8) · Brain Concussion (7) · Brain Edema (7) · Head Injuries, Closed (7) · Hematoma, Epidural, Spinal (7) · Brain Hemorrhage, Traumatic (6) · Wounds and Injuries (6) · Disorders of Environmental Origin (5) · Trauma, Nervous System (5) · Brain Diseases (3) · Central Nervous System Diseases (3)
Contusions (13) · Wounds, Nonpenetrating (13) · Brain Diseases (10) · Central Nervous System Diseases (10) · Nervous System Diseases (10) · Pathologic Processes (10) · Pathological Conditions, Signs and Symptoms (10) · Cardiovascular Diseases (9) · Cerebrovascular Disorders (9) · Hemorrhage (9) · Vascular Diseases (9) · Hematoma (8) · Intracranial Hemorrhages (8) · Trauma, Nervous System (8) · Intracranial Hemorrhage, Traumatic (7)
Cycloserine (1) · Exercise (1) · Glyburide (1) · Mannitol (1) · Saline Solution, Hypertonic (1) · Spectroscopy, Near-Infrared (1) · Standard of Care (1) · TOPS (1)
Children's Hospital Medical Center, Cincinnati (6) · Chinese University of Hong Kong (1) · Clionsky Neuro Systems Inc. (1) · Hadassah Medical Organization (1) · Massachusetts General Hospital (1) · National Institute of Mental Health and Neuro Sciences, India (1) · Remedy Pharmaceuticals, Inc. (1) · Wayne State University (1)
United States (9) · Israel (2) · France (1) · Germany (1) · Hong Kong (1) · India (1) · Italy (1) · Japan (1) · Spain (1)
Shari L Wade, PhD (2) · Shari L. Wade, PhD (2) · Brian P Walcott, MD (1) · Brian V Nahed, MD (1) · Dhaval Shukla, MCh (1) · Guy Rosenthal, MD (1) · H. Gerry Taylor, PhD (1) · Jean Peduzzi-Nelson, Ph.D. (1) · Keith O. Yeates, PhD (1) · McKay M Sohlberg, PhD (1) · Michael Kirkwood, PhD (1) · Mitchell I Clionsky, Ph.D (1) · Sameer A Sheth, MD PhD (1) · Shari Wade, PhD (1)
PMID 30413559, PMID 35170571, PMID 23640543, PMID 23753094, PMID 23790158, PMID 24781374, PMID 25583911, PMID 25738891, PMID 26461100, PMID 28389109, PMID 28836809, PMID 29096775, PMID 29097272, PMID 29617953, PMID 30499926, PMID 30738021, PMID 31405391, PMID 31556652
2018 (1)