20 completed, 5 withdrawn, 1 not yet recruiting, 1 recruiting. 28 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 28 | Completed 20, Withdrawn 5, Not yet recruiting 1, Recruiting 1, Unknown 1 |
Follow Helminthiasis: new trials by email Literature Review of Helminthiasis trials Research Report on Helminthiasis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Moxidectin Versus Ivermectin as Mass Drug Administration for the Control of Onchocerciasis and Other Neglected Tropical Diseases Moxidectin, Ivermectin - Onchocerciasis, Ascaris Lumbricoides Infection | Phase 4 | Recruiting | Kirby Institute | 52000 | 2025-08-04 | 2025-11-21 |
| Assessment of Combined Praziquantel and Albendazole vs Albendazole Alone to Treat Active Parenchymal Neurocysticercosis albendazole and praziquantel, Albendazole - Neurocysticercosis | Phase 4 | Not yet recruiting | R-Evolution Worldwide S.r.l. Impresa Sociale | 300 | 2024-06-01 | 2024-04-23 |
| Study of Safety, Tolerability and Clinical Outcomes of Egaten in Fascioliasis Patients (6 Years of Age or Older). Egaten (Triclabendazole) 250 mg tablets - Fascioliasis | Phase 4 | Completed | Novartis Pharmaceuticals | 301 | 2022-02-11 | 2026-11-06 |
| Cluster RCT of Co-administration Azithromycin, Albendazole & Ivermectin Administration of Albendazole on Day 1, Administration of Ivermectin on Day 1, Administration of Azithromycin on Day 1 - Trachoma, Lymphatic Filariases | Phase 4 | Completed | London School of Hygiene and Tropical Medicine | 13511 | 2021-12-01 | 2022-08-19 |
| Loiasis Cross-reactive Antigenemia and Treatment-related Adverse Events Ivermectin - Loiasis | Phase 4 | Completed | Washington University School of Medicine | 41 | 2021-07-30 | 2022-09-29 |
| Synbiotics Interventions for Managing Cirrhosis and Its Complications Entecavir 0.5 mg, A 10-g packet of lactulose oral solution and three capsules of probiotics, A 10-g packet of glucose oral solution and three capsules of starch - Cirrhosis, Liver, Metagonimiasis | Phase 4 | Completed | First Affiliated Hospital of Zhejiang University | 120 | 2019-11-24 | 2023-01-18 |
| Ivermectin Treatment in Patients With Onchocerciasis-associated Epilepsy Ivermectin - Ivermectin, Onchocerciasis | Phase 4 | Completed | Robert Colebunders | 91 | 2017-10-01 | 2019-01-07 |
| Triple Combinations Against Hookworm Infections in Lao Albendazole, Pyrantel Pamoate, Oxantel Pamoate - Hookworm Infection | Phase 4 | Completed | Swiss Tropical & Public Health Institute | 420 | 2017-09-27 | 2018-05-08 |
| Mebendazole Study Against Hookworm Infections in Children and Adolescents in Ghana Mebendazole - Hookworm Infections | Phase 4 | Withdrawn | PATH | 2017-09-01 | 2017-11-17 | |
| Efficacy and Safety of a Multi-dose Regimen of Mebendazole Against Hookworm in Children Treatment with one of the two regimens of mebendazole - Hookworm | Phase 4 | Completed | Jennifer Keiser | 186 | 2017-07-25 | 2019-06-17 |
| Twice Yearly Treatment for the Control of LF 400 μg/kg Ivermectin + 400 mg Albendazole - Lymphatic Filariasis, Helminth Infection | Phase 4 | Completed | Noguchi Memorial Institute for Medical Research | 1462 | 2017-05-19 | 2020-02-26 |
| Intestinal Microbiome Post-Azythromycin/Albendazole Treatment Azithromycin, Albendazole, Delayed treatment - Helminth Infection | Phase 4 | Withdrawn | University of California, San Francisco | 2017-01-01 | 2021-06-28 | |
| Effect of Concomitant Mansonella Perstans Microfilaremia on Immune Responses Following Single Dose Praziquantel in People With Schistosomiasis Praziquantel - Schistosomiasis | Phase 4 | Withdrawn | National Institute of Allergy and Infectious Diseases (NIAID) | 2016-04-06 | 2019-12-17 | |
| Effect of Schistosomiasis Mansoni on HIV Susceptibility and Female Genital Immunology Praziquantel - Schistosomiasis Mansoni, HIV | Phase 4 | Completed | University of Toronto | 34 | 2016-03-01 | 2016-10-27 |
| The Impact of Anthelmintic Treatment on the Incidence of Diarrheal Disease in Vietnamese School Children Albendazole, Placebo - Intestinal Helminthiasis, Diarrhea | Phase 4 | Withdrawn | Oxford University Clinical Research Unit, Vietnam | 2016-02-01 | 2016-12-15 | |
| Impact of Alternative Treatment Strategies and Delivery Systems for Soil-transmitted Helminths in Kenya albendazole - Helminthiasis, Nematode Infection | Phase 4 | Completed | London School of Hygiene and Tropical Medicine | 21761 | 2015-03-01 | 2018-08-31 |
| Safety Study of Combined Azithromycin, Ivermectin and Albendazole for Trachoma and Lymphatic Filariasis azithromycin, ivermectin, albendazole - Trachoma, Lymphatic Filariasis | Phase 4 | Withdrawn | Emory University | 2014-02-01 | 2014-05-22 | |
| Post-treatment Effects of Ivermectin (IVM) or Diethylcarbamazine (DEC) in Loiasis Diethylcarbamazine, Ivermectin - Loiasis | Phase 4 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 155 | 2012-04-01 | 2016-11-09 |
| Effect of Hookworm Elimination and Vitamin A Intervention on Iron Status of Preschool Children in Sichuan, China ZENTEL, ZENTEL and Vitamin A Soft Capsules - Anemia, Worm Infections | Phase 4 | Completed | Chengdu Maternal and Children's Health Care Hospital | 209 | 2012-03-01 | 2016-02-05 |
| Monitoring the Efficacy of Anthelmintics for the Treatment of Soil Transmitted Helminths P2 Mebendazole - Ascaris Lumbricoides, Ascaris Suum | Phase 4 | Completed | University Ghent | 250 | 2011-12-01 | 2014-12-05 |
Showing 20 of 28. Sign in to see all of them.
Elephantiasis, Filarial (5) · Trichuriasis (5) · Hookworm Infections (4) · Ancylostomiasis (3) · Trematode Infections (3) · Anemia (2) · Coinfection (2) · Epilepsy (2) · Loiasis (2) · Neglected Diseases (2) · Onchocerciasis (2) · Schistosomiasis (2) · Schistosomiasis mansoni (2) · Trachoma (2)
Infections (28) · Parasitic Diseases (27) · Nematode Infections (18) · Secernentea Infections (16) · Spirurida Infections (10) · Filariasis (9) · Vector Borne Diseases (9) · Hemic and Lymphatic Diseases (7) · Mosquito-Borne Diseases (6) · Strongylida Infections (6) · Adenophorea Infections (5) · Enoplida Infections (5) · Lymphatic Diseases (5) · Lymphedema (5)
Albendazole (14) · Ivermectin (7) · Mebendazole (5) · Praziquantel (5) · Azithromycin (2) · Diethylcarbamazine (2) · Albumins (1) · Artemether, Lumefantrine Drug Combination (1) · Doxycycline (1) · Levamisole (1) · Probiotics (1) · Pyrantel Pamoate (1) · Starch (1) · Therapeutics (1) · Treatment Delay (1)
London School of Hygiene and Tropical Medicine (2) · National Institute of Allergy and Infectious Diseases (NIAID) (2) · University Ghent (2) · Albert Schweitzer Hospital (1) · Centre d'Appui à la lutte contre la Maladie (1) · Chengdu Maternal and Children's Health Care Hospital (1) · Emory University (1) · First Affiliated Hospital of Zhejiang University (1) · Indian Council of Medical Research (1) · Janssen-Cilag Ltd. (1) · Jennifer Keiser (1) · Kirby Institute (1) · Natural History Museum, United Kingdom (1) · Navrongo Health Research Centre, Ghana (1) · Noguchi Memorial Institute for Medical Research (1)
Ethiopia (4) · Cameroon (3) · Ghana (3) · Tanzania (3) · Vietnam (3) · Angola (1) · Argentina (1) · Australia (1) · Brazil (1) · Cambodia (1) · China (1) · Colombia (1) · Democratic Republic of the Congo (1) · Egypt (1) · Gabon (1)
Amy D Klion, M.D. (2) · Abraham V Hodgson, MD, MPH, PhD (1) · Ana Lucia C Domingues, MD (1) · Andrea Graham, PhD (1) · Annette Olsen, PhD (1) · Dziedzom K de Souza, PhD (1) · Edmund L Browne, MD, MPH, PhD (1) · Ernest C Opoku, MD, MPH (1) · Huub C Gelderblom, MD, PhD, MPH (1) · Jacqueline Leung, MA (1) · Jennifer Keiser, PhD (1) · Jeremy Keenan, MD, MPH (1) · Jozef Vercruysse, PhD (1) · Kabemba E. Mwape, Prof. (1)
PMID 18775092, PMID 22189084, PMID 23981378, PMID 24550339, PMID 25299391, PMID 26482774, PMID 26691247, PMID 27266697, PMID 28329346, PMID 28855148, PMID 28969715, PMID 29673735, PMID 31006575, PMID 31193620, PMID 31314757, PMID 31398204, PMID 31923177, PMID 37152362, PMID 37180228