64 completed, 18 unknown, 7 not yet recruiting, 5 recruiting. 27 Not applicable, 17 Phase 2, 14 Phase 3, 8 Phase 1, 4 Phase 4.
Follow Schistosomiasis: new trials by email Literature Review of Schistosomiasis trials Research Report on Schistosomiasis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Different Treatment Frequencies for Hepatic Fibrosis Due to Schistosomiasis Praziquantel 40 mg/kg per dose given once annually, Praziquantel 40 mg/kg given three times per year - Schistosomiasis, Schistosoma Mansoni | Phase 2 / Phase 3 | Not yet recruiting | Rhode Island Hospital | 600 | 2026-11-01 | 2026-08-12 |
| Assessment of Right Ventricular-Pulmonary Arterial Coupling in Schistosomiasis-Associated Pulmonary Arterial Hypertension right heart catheterization for measure pulmonary artery pressure - Schistosomiasis | Not applicable | Not yet recruiting | Sohag University | 50 | 2026-07-01 | 2026-07-16 |
| Expanding Access to Preventive Chemotherapy Among Mobile and Migrant Populations Modified Mass Administration of Medicines Strategy, Albendazole 400 mg, Praziquantel 40 mg/kg - Onchocerciasis (River Blindness), Schistosomiasis | Not applicable | Recruiting | Uwemedimo Friday Ekpo | 5760 | 2026-07-01 | 2026-07-16 |
| Prevalence and Molecular Identification of Human Schistosomiasis Molecular phylogenetic and haplotype analysis - Schistosomiasis | Not yet recruiting | Assiut University | 359 | 2026-05-01 | 2026-03-19 | |
| Nanobody-based Schistosomiasis Urine Test Kit Research Because this is an observational study, participants are not assigned an intervention as part of the study. - Schistosomiasis Haematobia | Not yet recruiting | Pemba Ministry of Health Zanzibar | 2500 | 2026-04-01 | 2026-03-30 | |
| Long-Term Outcomes of Selexipag in Schistosomiasis-Associated Pulmonary Arterial Hypertension Pulmonary Arterial Hypertension (PAH) | Not yet recruiting | Caio Júlio César dos Santos Fernandes | 30 | 2026-03-01 | 2026-03-05 | |
| Risk Assessment of Community Spread of Multiple Endemic Infectious Diseases in a One Health Perspective Dengue, Chikungunya | Recruiting | Institut Pasteur du Cambodge | 10000 | 2025-12-18 | 2026-01-22 | |
| Protocol for Integrating Mass Drug Administration Into Primary Health Care in Western Kenya Primary Healthcare-Integrated Service Delivery, Standard Mass Drug Adminitsration service delivery - Soil Transmitted Helminth (STH) Infections, Schistosomiasis Infection | Not applicable | Completed | Amref Health Africa | 1229 | 2025-05-22 | 2026-04-02 |
| MATCHING - feMAle geniTal sCHistosomiasis IN miGrants Female Genital Schistosomiasis in Migrants Presenting to an Outpatient Clinic in Italy: Prevalence and Clinical Impact Cervical-vaginal swab - Female Genital Schistosomiasis | Not applicable | Recruiting | IRCCS Sacro Cuore Don Calabria di Negrar | 96 | 2025-02-20 | 2026-03-20 |
| Female Genital Schistosomiasis in Migrant Women: A Pilot Study Gynecology consultation, Transvaginal ultrasound, PCR Schistosoma spp - Diagnostic, Schistosomiasis | Not applicable | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 50 | 2025-02-10 | 2025-02-14 |
| Performance of Tests for Schistosoma Haematobium Diagnosis S. haematobium egg detection by single urine filtration, S. haematobium egg detection by quintuple urine filtration, S. haematobium egg detection by artificial intelligence (AI) microscopy - Schistosoma Haematobium | Completed | Stefanie Knopp | 801 | 2025-02-10 | 2025-09-19 | |
| Introduction of Arpraziquantel Treatment for Schistosomiasis Control in Preschool-aged Children in Endemic Areas: A Small-scale Public Health Intervention Study Arpraziquantel 150mg dispersible tablet - Schistosomiasis | Recruiting | Peter Steinmann | 18500 | 2024-11-25 | 2025-09-24 | |
| Sm-p80 Schistosomiasis Challenge Study Sm-p80 + GLA-SE Vaccine, Placebo, Schistosoma mansoni infection - Schistosoma Mansoni, Schistosomiasis | Phase 2 | Unknown | Leiden University Medical Center | 48 | 2024-09-01 | 2023-10-17 |
| Assessment of Infection Activity in Travelers and Migrants Diagnosed With Chronic Schistosomiasis UCP-LF CAA assay - Schistosomiasis | Not applicable | Recruiting | IRCCS Sacro Cuore Don Calabria di Negrar | 278 | 2024-06-28 | 2025-04-20 |
| Effectiveness and Cost-effectiveness of Integrated Model for Malaria and Helminth Control Sulphadoxine-pyrimethamine and Amodiaquine - Malaria, Soil Transmitted Helminths | Not applicable | Unknown | London School of Hygiene and Tropical Medicine | 1200 | 2024-05-27 | 2024-03-20 |
| Health Education Model Led by Community Health Volunteers. health education - Schistosomiasis, Health Education | Not applicable | Completed | Pemba Ministry of Health Zanzibar | 978 | 2024-02-24 | 2026-10-08 |
| Delivering a Multi-disease Screening Tool to Migrant Populations Clinical decision support system for screening of migrants using the ISMiHealth software tool. - Hiv, Hepatitis B | Not applicable | Completed | Barcelona Institute for Global Health | 980 | 2024-01-01 | 2025-05-13 |
| A Study to Evaluate the Safety, Tolerability, and Immunogenicity of the rSm-p80 + GLA-SE (SchistoShield®) Candidate Vaccine in Healthy Adults in Burkina Faso and Madagascar rSm-p80 + GLA-SE - Schistosomiasis | Phase 1 | Completed | International Vaccine Institute | 120 | 2023-11-17 | 2026-04-29 |
| Evaluation of an AI-DP for STH Deworming Programs: a Study Protocol Artificial Intelligence Digital Pathology - Soil Transmitted Helminths, Schistosomiasis Mansoni | Unknown | Enaiblers AB | 1100 | 2023-10-01 | 2023-10-02 | |
| Possible Diagnostic Protein Markers in Schistosoma Related Bladder Diseases. Immunohistochemistry staining,, microscopic examination of urine - Schistosoma Haematobium | Not yet recruiting | Assiut University | 120 | 2023-10-01 | 2023-07-12 |
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Schistosomiasis haematobia (21) · Malaria (12) · Schistosomiasis mansoni (12) · Anemia (7) · Disease (4) · Helminthiasis (3) · Infections (3) · Neglected Diseases (3) · Schistosomiasis japonica (3) · Tuberculosis (3) · Communicable Diseases (2) · Diabetes Mellitus (2) · Elephantiasis, Filarial (2) · Giardiasis (2)
Parasitic Diseases (97) · Trematode Infections (97) · Vector Borne Diseases (96) · Helminthiasis (94) · Infections (94) · Urogenital Diseases (25) · Female Urogenital Diseases (22) · Female Urogenital Diseases and Pregnancy Complications (22) · Male Urogenital Diseases (22) · Urinary Tract Infections (21) · Urologic Diseases (21) · Pathological Conditions, Signs and Symptoms (16) · Pathologic Processes (14) · Protozoan Infections (14)
Praziquantel (30) · Albendazole (5) · fanasil, pyrimethamine drug combination (3) · Amodiaquine (2) · Artemether, Lumefantrine Drug Combination (2) · Mefloquine (2) · Microscopy (2) · SM14 protein, Schistosoma mansoni (2) · glucopyranosyl lipid-A (2) · Arachidonic Acid (1) · Artesunate (1) · Drugs, Generic (1) · GLA-AF adjuvant (1) · Hepatitis B Vaccines (1) · Iron (1)
DBL -Institute for Health Research and Development (10) · National Institute of Allergy and Infectious Diseases (NIAID) (8) · Leiden University Medical Center (5) · Oswaldo Cruz Foundation (5) · Centre de Recherche Médicale de Lambaréné (4) · IRCCS Sacro Cuore Don Calabria di Negrar (4) · Assistance Publique - Hôpitaux de Paris (2) · Assiut University (2) · Kenya Medical Research Institute (2) · London School of Hygiene and Tropical Medicine (2) · Makerere University (2) · Merck KGaA, Darmstadt, Germany (2) · Pemba Ministry of Health Zanzibar (2) · Rhode Island Hospital (2) · Sohag University (2)
Uganda (11) · Senegal (9) · Kenya (8) · Tanzania (7) · Brazil (5) · Côte d’Ivoire (5) · Egypt (5) · Gabon (5) · Netherlands (5) · Italy (4) · Germany (3) · Madagascar (3) · United States (3) · Burkina Faso (2) · France (2)
Annette Olsen, PhD (2) · Francisca Mutapi, PhD (2) · Miriam Tendler, MD, PhD (2) · Abraham V Hodgson, MD, MPH, PhD (1) · Alison Elliot (1) · Allen Nalugwa, PhD (1) · Amy D Klion, M.D. (1) · Ana Lucia C Domingues, MD (1) · Andrea Kreidenweiss, PhD (1)
PMID 26571311, PMID 19150418, PMID 2022660, PMID 21298114, PMID 23284726, PMID 33998661, PMID 19780472, PMID 19802383, PMID 20705516, PMID 21729382, PMID 22802974, PMID 23175561, PMID 23596262, PMID 24063608, PMID 24824051, PMID 25624403, PMID 25733630, PMID 25793584, PMID 26282537, PMID 26511959, PMID 27441564, PMID 28472067, PMID 29131820, PMID 29351649, PMID 29546300, PMID 30074085, PMID 30469320, PMID 30532268, PMID 30615787, PMID 30687792, PMID 30969960, PMID 31188820, PMID 32066978, PMID 32196506, PMID 32307517, PMID 32439737, PMID 32993559, PMID 33861768, PMID 34168029, PMID 35788749, PMID 35922819, PMID 36315579, PMID 36342912, PMID 36548444, PMID 36581796, PMID 36893784, PMID 36996185, PMID 37438520, PMID 37722662, PMID 37957702
2008 (1), 2016 (1), 5UM1AI148373-03 (1), R01AI184979 (1), R01HD095562 (1), U01AI066050 (1)