17 completed, 9 unknown, 6 not yet recruiting, 3 recruiting. 38 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 38 | Completed 17, Unknown 9, Not yet recruiting 6, Recruiting 3, Enrolling by invitation 2, Withdrawn 1 |
Follow Gastrointestinal Dysfunction: new trials by email Literature Review of Gastrointestinal Dysfunction trials Research Report on Gastrointestinal Dysfunction
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| FMT for 90-Day Outcome of Clinical Use in ICU Sepsis Gut microbiota suspension - Sepsis, Critical Illness | Not applicable | Not yet recruiting | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 60 | 2026-10-15 | 2026-09-24 |
| FMT for Feeding Intolerance Due to Gastrointestinal Dysfunction in Critically Ill Patients Fecal microbiota transplantation (FMT) - Feeding Intolerance, Gastrointestinal Dysfunction | Not applicable | Not yet recruiting | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 60 | 2026-10-01 | 2026-09-16 |
| Ear-Vagus Nerve Stimulation and Body Acupuncture for Gut Motility in Elderly ICU Patients Standard Care, Body Acupuncture, Transcutaneous Auricular Vagus Nerve Stimulation - Gastrointestinal Dysfunction, Critical Illness | Not applicable | Not yet recruiting | The First Affiliated Hospital with Nanjing Medical University | 60 | 2026-09-01 | 2026-10-06 |
| Study on Neostigmine Acupoint Injection at Zusanli(ST36) for Treating Mechanical Ventilation-Associated Gastrointestinal Dysfunction Neostigmine Acupoint Injection, Neostigmine subcutaneous injection, Acupoint normal saline injection - Gastrointestinal Dysfunction | Not applicable | Not yet recruiting | Southeast University, China | 90 | 2026-07-01 | 2026-07-09 |
| Oliceridine for Gastrointestinal Dysfunction Experimental: Oliceridine group, Active Comparator: Classical opioid group - Gastrointestinal Dysfunction | Not applicable | Not yet recruiting | Beijing Tiantan Hospital | 176 | 2026-07-01 | 2026-06-16 |
| Clinical Study on the Treatment of Gastrointestinal Dysfunction After Knee Joint Surgery Under General Anesthesia With Floating Needle Fu's Acupuncture group, Mosapride - Gastrointestinal Dysfunction | Not applicable | Enrolling by invitation | Zhenyu Zhang | 72 | 2026-03-27 | 2026-05-26 |
| Prognosis and Diagnosis of Acute Gastrointestinal Dysfunction in Cardiac Surgery Patients additional blood testing for specific and non-specific markers of intestinal dysfunction, ultrasound examination of abdominal organs and measurement of intra-abdominal pressure - Gastrointestinal Dysfunction, Cardiac Surgery Intensive Care Treatment | Not applicable | Not yet recruiting | Petrovsky National Research Centre of Surgery | 100 | 2026-03-10 | 2026-02-19 |
| Effect of HFNC on Incidence of Hypoxia During Sedated Gastrointestinal Endoscopy in Critical Patients High-flow nasal catheter oxygen, regular nasal catheter oxygen - Liver Cirrhosis, Polyps of Colon | Not applicable | Recruiting | Zhejiang University | 450 | 2025-11-20 | 2026-01-20 |
| Achieving nuTritional Target in criticAlly Ill patieNts With iMpairEd gastroiNtesTinal Dysfunction Supplemental Parenteral Nutrition (SPN) - Parenteral Nutrition, Gastroparesis | Not applicable | Recruiting | Romanian Society for Enteral and Parenteral Nutrition | 164 | 2024-10-01 | 2024-11-06 |
| The Effect of Probiotic Supported Yogurt Consumption on Gastrointestinal Symptoms Activia Probiotic Yogurt - Gastrointestinal Dysfunction | Not applicable | Withdrawn | Eastern Mediterranean University | 2024-09-01 | 2025-08-12 | |
| Determination of the Safety and Efficacy of Two Probiotic Strains Placebo 1 to Probiotic A, Probiotic A to Placebo 1, Placebo 2 to Probiotic B - Gastrointestinal Dysfunction | Not applicable | Unknown | The Archer-Daniels-Midland Company | 100 | 2024-06-01 | 2024-06-20 |
| A Study to Assess the Gut Health Effects of Heat-killed Post-biotics in Overweight and Obese Adults EF2001, beLP1, Placebo - Gastrointestinal Dysfunction | Not applicable | Completed | Vedic Lifesciences Pvt. Ltd. | 155 | 2024-04-14 | 2025-06-25 |
| RCT of Gut-directed Hypnotherapy in Ehlers-Danlos Syndromes and Generalized Hypermobility Spectrum Disorders Gut-directed hypnotherapy, Standard Medical Therapy - Ehlers-Danlos Syndrome, Irritable Bowel Syndrome | Not applicable | Unknown | University Health Network, Toronto | 74 | 2024-04-01 | 2024-03-22 |
| The Effects of Acupressure on Improving Postoperative Gastrointestinal Symptom Distress in Esophageal Cancer Patients acupressure - Esophageal Cancer, Gastrointestinal Dysfunction | Not applicable | Completed | CHEN, CHIA-CHEN | 48 | 2024-03-27 | 2025-08-07 |
| Personalized GI Motility Responses to Diet Whole grain rye bread, Refined grain rye bread - Nutritional and Metabolic Diseases, Gastrointestinal Dysfunction | Not applicable | Unknown | University of Illinois at Urbana-Champaign | 50 | 2024-03-07 | 2024-04-26 |
| Low Pressure Pneumoperitoneum and Postoperative Ileus Pneumoperitoneum Pressure, Neuromuscular blockade, Pneumoperitoneum insufflation device - Postoperative Ileus, Gastrointestinal Dysfunction | Not applicable | Recruiting | Ohio State University | 125 | 2024-03-06 | 2025-11-03 |
| Hemp Fiber Ingestion and Gut Permeability After Exercise High Dose Hemp Fiber Bar, Low Dose Hemp Fiber Bar, Placebo - Gastrointestinal Dysfunction, Metabolic Disturbance | Not applicable | Completed | Appalachian State University | 25 | 2023-12-09 | 2024-09-26 |
| The Chemo-Gut Probiotic Trial for Cancer Survivors Multistrain Probiotic, Placebo - Cancer, Psychosocial Problem | Not applicable | Unknown | University of Calgary | 66 | 2023-11-10 | 2023-10-18 |
| Electroacupuncture (EA) Promotes Gastrointestinal Functional Recovery After Radical Colorectal Cancer Surgery Electroacupuncture group, Sham EA group, Conventional Treatment group - Colorectal Cancer, Gastrointestinal Dysfunction | Not applicable | Completed | Shanghai Yueyang Integrated Medicine Hospital | 305 | 2023-11-06 | 2026-09-30 |
| Promephy - Metabolic Fate of Plant-based Proteins Dairy based protein, Mixed protein, Plant-based protein 1 - Amino Acid Change, Gastrointestinal Dysfunction | Not applicable | Completed | Anglia Ruskin University | 20 | 2023-05-02 | 2025-02-05 |
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Critical Illness (4) · Anxiety Disorders (2) · Constipation (2) · Dysbiosis (2) · Neoplasms (2) · Pain (2) · Autoimmune Diseases (1) · Cardiovascular Diseases (1) · Cognition Disorders (1) · Colonic Polyps (1) · Colorectal Neoplasms (1) · Diabetes Mellitus (1) · Diarrhea (1) · Ehlers-Danlos Syndrome (1) · Endocrine System Diseases (1)
Pathological Conditions, Signs and Symptoms (11) · Digestive System Diseases (7) · Pathologic Processes (7) · Signs and Symptoms (7) · Gastrointestinal Diseases (5) · Disease Attributes (4) · Intestinal Diseases (4) · Neurologic Manifestations (4) · Nutritional and Metabolic Diseases (4) · Signs and Symptoms, Digestive (4) · Mental Disorders (3) · Cardiovascular Diseases (2) · Colonic Diseases (2) · Digestive System Neoplasms (2) · Gastrointestinal Neoplasms (2)
Acupressure (2) · Yogurt (2) · Acupuncture Therapy (1) · Exercise (1) · Fecal Microbiota Transplantation (1) · Neuromuscular Blockade (1) · Saline Solution (1) · Standard of Care (1) · Therapeutics (1) · mosapride (1) · polydextrose (1)
University of Illinois at Urbana-Champaign (3) · Union Hospital, Tongji Medical College, Huazhong University of Science and Technology (2) · Aalborg University Hospital (1) · Anglia Ruskin University (1) · Appalachian State University (1) · Beijing Tiantan Hospital (1) · CHEN, CHIA-CHEN (1) · Coconut Goodness Food Products Inc. (1) · Colorado State University (1) · Eastern Mediterranean University (1) · Guangdong Provincial Hospital of Traditional Chinese Medicine (1) · Instituto de Investigación Hospital Universitario La Paz (1) · Istanbul Medeniyet University (1) · Johns Hopkins University (1) · Kahramanmaras Sutcu Imam University (1)
United States (11) · China (7) · Turkey (Türkiye) (2) · United Kingdom (2) · Canada (1) · Cyprus (1) · Denmark (1) · India (1) · Romania (1) · Russia (1) · Spain (1) · Taiwan (1)
Andrea Lawless, MD (1) · Chia-Chen Chen (1) · Cristian Cobilinschi, MD, PhD (1) · David C Nieman, DrPH (1) · Dustin Lee, PhD (1) · Essi Sarkkinen, PhD (1) · Fedias L Christofi, Ph.D., AGAF (1) · Guillermo Tearney, M.D, PhD. (1) · Jia Zhou, M.D. (1) · Jian-meng Liu, PhD (1) · Joseph Lamb, MD (1) · Julie M Deleemans, PhD (1)
PMID 38830472, PMID 14696681, PMID 21963582, PMID 23448746, PMID 24336217, PMID 25276717, PMID 25603226, PMID 28483182, PMID 28903954, PMID 30448193, PMID 31683779, PMID 32414423, PMID 33408197, PMID 33967207, PMID 34024548, PMID 34684372, PMID 36088342, PMID 36266668, PMID 38546822, PMID 39652211, PMID 42824179, PMID 8792684, PMID 8982828
R01DA003890 (1)