30 completed, 15 unknown, 8 not yet recruiting, 4 recruiting. 38 Not applicable, 3 Phase 1, 2 Phase 2, 2 Phase 3, 2 Phase 4.
Follow Gastrointestinal Dysfunction: new trials by email Literature Review of Gastrointestinal Dysfunction trials Research Report on Gastrointestinal Dysfunction
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| FMT for 90-Day Outcome of Clinical Use in ICU Sepsis Gut microbiota suspension - Sepsis, Critical Illness | Not applicable | Not yet recruiting | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 60 | 2026-10-15 | 2026-09-24 |
| FMT for Feeding Intolerance Due to Gastrointestinal Dysfunction in Critically Ill Patients Fecal microbiota transplantation (FMT) - Feeding Intolerance, Gastrointestinal Dysfunction | Not applicable | Not yet recruiting | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 60 | 2026-10-01 | 2026-09-16 |
| Postoperative GI Dysfunction and Nutrition in Malnourished Cancer Surgery Patients Serotonin (e.g., serotonin adipinate), Standard Prokinetic Therapy (excluding serotonin) - Gastrointestinal Dysfunction, Malnutrition | Not yet recruiting | Arma Ltd. | 120 | 2026-10-01 | 2026-06-03 | |
| Ear-Vagus Nerve Stimulation and Body Acupuncture for Gut Motility in Elderly ICU Patients Standard Care, Body Acupuncture, Transcutaneous Auricular Vagus Nerve Stimulation - Gastrointestinal Dysfunction, Critical Illness | Not applicable | Not yet recruiting | The First Affiliated Hospital with Nanjing Medical University | 60 | 2026-09-01 | 2026-10-06 |
| Study on Neostigmine Acupoint Injection at Zusanli(ST36) for Treating Mechanical Ventilation-Associated Gastrointestinal Dysfunction Neostigmine Acupoint Injection, Neostigmine subcutaneous injection, Acupoint normal saline injection - Gastrointestinal Dysfunction | Not applicable | Not yet recruiting | Southeast University, China | 90 | 2026-07-01 | 2026-07-09 |
| Oliceridine for Gastrointestinal Dysfunction Experimental: Oliceridine group, Active Comparator: Classical opioid group - Gastrointestinal Dysfunction | Not applicable | Not yet recruiting | Beijing Tiantan Hospital | 176 | 2026-07-01 | 2026-06-16 |
| Clinical Study on the Treatment of Gastrointestinal Dysfunction After Knee Joint Surgery Under General Anesthesia With Floating Needle Fu's Acupuncture group, Mosapride - Gastrointestinal Dysfunction | Not applicable | Enrolling by invitation | Zhenyu Zhang | 72 | 2026-03-27 | 2026-05-26 |
| Prognosis and Diagnosis of Acute Gastrointestinal Dysfunction in Cardiac Surgery Patients additional blood testing for specific and non-specific markers of intestinal dysfunction, ultrasound examination of abdominal organs and measurement of intra-abdominal pressure - Gastrointestinal Dysfunction, Cardiac Surgery Intensive Care Treatment | Not applicable | Not yet recruiting | Petrovsky National Research Centre of Surgery | 100 | 2026-03-10 | 2026-02-19 |
| Effect of HFNC on Incidence of Hypoxia During Sedated Gastrointestinal Endoscopy in Critical Patients High-flow nasal catheter oxygen, regular nasal catheter oxygen - Liver Cirrhosis, Polyps of Colon | Not applicable | Recruiting | Zhejiang University | 450 | 2025-11-20 | 2026-01-20 |
| Post-Cesarean Gastrointestinal Dysfunction Cesarean Section Surgery, TAP Blocks | Completed | Elazıg Fethi Sekin Sehir Hastanesi | 102 | 2025-06-15 | 2025-07-18 | |
| Efficacy of Fuzheng Tongfu Jiedu Prescription for Treating Gastrointestinal Dysfunction Associated With Sepsis Fuzheng Tongfu Jiedu prescription (FZTFJD), Placebo - Sepsis Abdominal, Gastrointestinal Dysfunction | Phase 1 / Phase 2 | Not yet recruiting | Dongzhimen Hospital, Beijing | 70 | 2025-04-25 | 2025-04-18 |
| Achieving nuTritional Target in criticAlly Ill patieNts With iMpairEd gastroiNtesTinal Dysfunction Supplemental Parenteral Nutrition (SPN) - Parenteral Nutrition, Gastroparesis | Not applicable | Recruiting | Romanian Society for Enteral and Parenteral Nutrition | 164 | 2024-10-01 | 2024-11-06 |
| Traditional Chinese Acupoint Massage for Gastrointestinal Function Recovery Traditional Chinese Acupoint Message, Intestinal Barrier | Withdrawn | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 2024-10-01 | 2024-09-19 | ||
| The Effect of Probiotic Supported Yogurt Consumption on Gastrointestinal Symptoms Activia Probiotic Yogurt - Gastrointestinal Dysfunction | Not applicable | Withdrawn | Eastern Mediterranean University | 2024-09-01 | 2025-08-12 | |
| Evaluating Perioperative Outcomes: Dexmedetomidine vs Lignocaine in Laparoscopic Chlolecystectomy inj. dexmedetomidine infusion @ 0.2-0.4 μg/kg/h, inj. lignocaine infusion @1-2 mg/kg/h - Hemodynamics Instability, Post Operative Pain | Phase 2 / Phase 3 | Recruiting | Sahiwal medical college sahiwal | 140 | 2024-08-06 | 2024-12-18 |
| Prospective, Multicentre Study to Validate the GastroIntestinal Dysfunction Score (GIDS) and Describe Prevalence, Outcomes, and Management of Phosphate Disorders in Intensive Care Patients Data collection - Gastrointestinal Dysfunction | Completed | University Hospitals of North Midlands NHS Trust | 92 | 2024-07-26 | 2025-07-03 | |
| Gastrointestinal Dysfunction in Aortic Surgery Patients No intervention - Aortic Aneurysm, Gastrointestinal Dysfunction | Unknown | Instituto Nacional de Cardiologia Ignacio Chavez | 114 | 2024-07-23 | 2024-07-24 | |
| Determination of the Safety and Efficacy of Two Probiotic Strains Placebo 1 to Probiotic A, Probiotic A to Placebo 1, Placebo 2 to Probiotic B - Gastrointestinal Dysfunction | Not applicable | Unknown | The Archer-Daniels-Midland Company | 100 | 2024-06-01 | 2024-06-20 |
| A Study to Assess the Gut Health Effects of Heat-killed Post-biotics in Overweight and Obese Adults EF2001, beLP1, Placebo - Gastrointestinal Dysfunction | Not applicable | Completed | Vedic Lifesciences Pvt. Ltd. | 155 | 2024-04-14 | 2025-06-25 |
| RCT of Gut-directed Hypnotherapy in Ehlers-Danlos Syndromes and Generalized Hypermobility Spectrum Disorders Gut-directed hypnotherapy, Standard Medical Therapy - Ehlers-Danlos Syndrome, Irritable Bowel Syndrome | Not applicable | Unknown | University Health Network, Toronto | 74 | 2024-04-01 | 2024-03-22 |
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Critical Illness (6) · Constipation (3) · Sepsis (3) · Anxiety Disorders (2) · Autoimmune Diseases (2) · Cognition Disorders (2) · Colorectal Neoplasms (2) · Dysbiosis (2) · Endocrine System Diseases (2) · Gastrointestinal Diseases (2) · Infant Nutrition Disorders (2) · Inflammatory Bowel Diseases (2) · Malabsorption Syndromes (2) · Neoplasms (2) · Pain (2)
Pathological Conditions, Signs and Symptoms (21) · Pathologic Processes (16) · Digestive System Diseases (13) · Gastrointestinal Diseases (10) · Signs and Symptoms (10) · Intestinal Diseases (8) · Nutritional and Metabolic Diseases (8) · Mental Disorders (7) · Disease Attributes (6) · Neurologic Manifestations (6) · Neoplasms (5) · Neoplasms by Site (5) · Signs and Symptoms, Digestive (5) · Digestive System Neoplasms (4) · Metabolic Diseases (4)
Acupressure (2) · Yogurt (2) · Acupuncture Therapy (1) · Data Collection (1) · Dexmedetomidine (1) · Diagnostic Imaging (1) · Exercise (1) · Fecal Microbiota Transplantation (1) · Glucose Tolerance Test (1) · Glycopyrrolate (1) · Latent Class Analysis (1) · Lidocaine (1) · Meperidine (1) · Midazolam (1) · Neostigmine (1)
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology (3) · University of Illinois at Urbana-Champaign (3) · Metagenics, Inc. (2) · University of Nottingham (2) · Aalborg University Hospital (1) · Advanced Endoscopy Research, Robert Wood Johnson Medical School Rutgers University (1) · Aldy Heriwardito (1) · Anglia Ruskin University (1) · Appalachian State University (1) · Arma Ltd. (1) · Beijing Tiantan Hospital (1) · CHEN, CHIA-CHEN (1) · Cancer Institute and Hospital, Chinese Academy of Medical Sciences (1) · Cell to Cure ApS (1) · Coconut Goodness Food Products Inc. (1)
United States (16) · China (11) · United Kingdom (5) · Turkey (Türkiye) (3) · Canada (2) · Denmark (2) · Russia (2) · Australia (1) · Cyprus (1) · France (1) · India (1) · Indonesia (1) · Mexico (1) · Pakistan (1) · Romania (1)
Joseph Lamb, MD (2) · Adeel Riaz, MD (1) · Alan Smyth (1) · Aldy Heriwardito, MD (1) · Andrea Lawless, MD (1) · Chengfeng Wang, B.A. (1) · Chia-Chen Chen (1) · Conor Delaney, MD, PhD (1) · Cristian Cobilinschi, MD, PhD (1) · David C Nieman, DrPH (1) · Dawei Liu, MSc. (1) · Dustin Lee, PhD (1) · Essi Sarkkinen, PhD (1)
PMID 38830472, PMID 14595310, PMID 14696681, PMID 19617584, PMID 21963582, PMID 23448746, PMID 24336217, PMID 25276717, PMID 25603226, PMID 25685266, PMID 28483182, PMID 28903954, PMID 30448193, PMID 31683779, PMID 31775838, PMID 32414423, PMID 33408197, PMID 33967207, PMID 34024548, PMID 34684372, PMID 36088342, PMID 36266668, PMID 36730114, PMID 37141073, PMID 37305080, PMID 38546822, PMID 38713274, PMID 39652211, PMID 42824179, PMID 8792684, PMID 8982828
R01DA003890 (1)