14 completed, 2 terminated, 2 unknown. 16 Not applicable, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 16 | Completed 12, Terminated 2, Unknown 2 |
| Phase 2 | 2 | Completed 2 |
Follow polydextrose: new trials by email Literature Review of polydextrose trials Research Report on polydextrose
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Hepatic Encephalopathy Prevention With Polydextrose After TIPS: Pilot Study (POEME) Polydextrose - Hepatic Encephalopathy | Not applicable | Unknown | University Hospital, Toulouse | 30 | 2022-05-09 | 2024-04-30 |
| Polydextrose for Patients With Chronic Kidney Disease Polydextrose - Chronic Kidney Diseases, Constipation | Not applicable | Completed | Universidade Federal Fluminense | 40 | 2021-03-30 | 2022-04-20 |
| A Clinical Study to Assess the Effect of Novel Glycans on Nitrogen Metabolism of the Gut in Healthy Subjects KB195, Polydextrose, Pullulan - Healthy | Not applicable | Completed | Kaleido Biosciences | 47 | 2017-09-18 | 2020-10-26 |
| Fiber Effects on Glycemic Index Polydextrose, Control Treatment - Healthy | Not applicable | Completed | Clinical Nutrition Research Center, Illinois Institute of Technology | 20 | 2016-07-02 | 2021-01-27 |
| Effect of Fiber on Glycemic Index 8 g Polydextrose, 12 g Polydextrose, 16 g Polydextrose - Healthy | Not applicable | Completed | Clinical Nutrition Research Center, Illinois Institute of Technology | 40 | 2015-11-01 | 2021-01-27 |
| Effect of Three Fibres on Glycaemic and Insulinaemic Responses in Healthy Adult Volunteers Experimental Dietary Fibre 1, Experimental Dietary Fibre 2, Polydextrose - Healthy Volunteers | Not applicable | Completed | Danisco | 13 | 2015-09-01 | 2016-07-27 |
| Dose-ranging Efficacy of Polydextrose Supplement on Colonic Transit Time and Symptoms in Adults With Functional Constipation Litesse powder containing 12 g polydextrose, Litesse powder containing 8 g polydextrose, Litesse powder containing 4 g polydextrose - Functional Constipation | Phase 2 | Completed | KGK Science Inc. | 192 | 2015-04-01 | 2018-11-09 |
| Assessing a Polydextrose Containing Soup on Food Intake, Appetite and Biomarkers of Satiation and Satiety Polydextrose, Control - Satiation, Satiety | Not applicable | Terminated | University of Liverpool | 42 | 2014-11-01 | 2016-01-07 |
| Gastrointestinal Tolerability Following Multiple Servings of a Novel Dietary Fiber Negative Control, Positive Fiber Control, Novel Fiber - Signs and Symptoms, Digestive | Not applicable | Completed | Cargill | 45 | 2014-10-01 | 2015-08-26 |
| Acute Gastrointestinal Tolerability Following a Single Serving of a Novel Dietary Fiber Novel Fiber, Positive Fiber control, Negative Control - Signs and Symptoms, Digestive | Not applicable | Completed | Cargill | 45 | 2014-09-01 | 2015-08-21 |
| Appetite Suppression Trial With Polydextrose 12.5 g polydextrose, glucose syrup - Body Weight, Non-restrained Eaters | Not applicable | Completed | W.J. Pasman | 32 | 2014-05-01 | 2022-06-06 |
| The Effect of a Bifidobacterium and Polydextrose on Body Fat Mass Bifidobacterium animalis ssp. lactis 420, Polydextrose, Placebo - Obesity, Hyperglycemia | Phase 2 | Completed | Danisco | 225 | 2013-11-01 | 2016-02-02 |
| Effect of Soy Protein and Polydextrose on Food Intake in Young Chinese Adult Males Soy Protein, Polydextrose - Obesity, Satiety | Not applicable | Completed | Singapore Institute of Food and Biotechnology Innovation | 27 | 2013-06-01 | 2015-07-30 |
| Effect of Polydextrose on Fecal Bulk and Bowel Function in Mildly Constipated Subjects Polydextrose, placebo-controlled - Constipation, Gastrointestinal Dysfunction | Not applicable | Completed | Tate & Lyle | 51 | 2012-11-01 | 2022-04-04 |
| Dose-Responsive Effect of Polydextrose on Whole Gut Transit Time Polydextrose, low dose, Polydextrose, medium dose, Polydextrose, high dose - Functional Constipation | Not applicable | Terminated | Danisco | 59 | 2012-03-01 | 2016-01-22 |
| Tolerance and Utilization of Polydextrose, Inulin, and Soluble Corn Fiber polydextrose, soluble corn fiber - Tolerance | Not applicable | Completed | University of Illinois at Urbana-Champaign | 25 | 2010-07-01 | 2014-05-14 |
| Chemoprevention of Colorectal Cancer: the Role of Non-digestible Carbohydrates Maltodextrin and Amioca starch, Hi-maize 260, Polydextrose - Colorectal Cancer | Not applicable | Unknown | Newcastle University | 75 | 2010-05-01 | 2011-10-26 |
| Soluble Dietary Fibres in the Prevention of Type 2 Diabetes Mellitus Polydextrose and soluble gluco fibre - Type 2 Diabetes Mellitus, Obesity | Not applicable | Completed | Maastricht University Medical Center | 60 | 2010-03-01 | 2018-01-09 |
Constipation (4) · Obesity (3) · Signs and Symptoms, Digestive (2) · Body Weight (1) · Colorectal Neoplasms (1) · Diabetes Mellitus (1) · Diabetes Mellitus, Type 2 (1) · Endotoxemia (1) · Hepatic Encephalopathy (1) · Hyperglycemia (1) · Insulin Resistance (1) · Renal Insufficiency, Chronic (1)
Danisco (3) · Cargill (2) · Clinical Nutrition Research Center, Illinois Institute of Technology (2) · KGK Science Inc. (1) · Kaleido Biosciences (1) · Maastricht University Medical Center (1) · Newcastle University (1) · Singapore Institute of Food and Biotechnology Innovation (1) · Tate & Lyle (1) · Universidade Federal Fluminense (1) · University Hospital, Toulouse (1) · University of Illinois at Urbana-Champaign (1) · University of Liverpool (1) · W.J. Pasman (1)
United Kingdom (3) · United States (3) · Netherlands (2) · Brazil (1) · Canada (1) · Finland (1) · France (1) · Italy (1)
Aila Rissanen, MD (1) · Britt Britt Burton-Freeman, Ph.D (1) · Britt M Burton-Freeman, Ph.D (1) · Essi Sarkkinen, PhD (1) · George Fahey, Jr, PhD (1) · Jason CG Halford, Professor (1) · Joanne A Harrold, Doctor (1) · John Mathers, PhD (1) · Mark Wingertzahn, PhD (1) · Naguib Muhsen, MD (1) · Naomi Willis, PhD (1) · Silvio Danese, MD (1) · Tetyana Pelipyagina, MD (1)
PMID 11079736, PMID 18236693, PMID 18978177, PMID 19094263, PMID 25527750, PMID 27810310, PMID 27916475, PMID 28077379, PMID 28276900, PMID 28418082, PMID 30525950, PMID 37321430, PMID 42489745