3 completed, 3 terminated, 2 unknown. 8 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 8 | Completed 3, Terminated 3, Unknown 2 |
| Phase 2 | 1 | Terminated 1 |
Follow Encephalomalacia: new trials by email Literature Review of Encephalomalacia trials Research Report on Encephalomalacia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Erythropoietin in Premature Infants on White Matter Lesions and Neurodevelopmental Outcome Erythropoietin, Normal saline - Premature Infants, Intracranial Hemorrhages | Phase 3 | Unknown | First Affiliated Hospital Xi'an Jiaotong University | 400 | 2017-04-10 | 2017-10-02 |
| Management of Hypotension In the Preterm Infant Dopamine hydrochloride, Dextrose 5% - Hypotension, Low Blood Pressure | Phase 3 | Terminated | University College Cork | 58 | 2015-02-01 | 2019-10-02 |
| Inhaled Nitric Oxide and Neuroprotection in Premature Infants inhaled nitric oxide, oxygen - Prematurity, Bronchopulmonary Dysplasia | Phase 2 / Phase 3 | Terminated | University of Chicago | 273 | 2008-05-01 | 2024-10-17 |
| Probiotics for the Prevention of Premature Birth and Neonatal Related Morbidity Lactobacillus rhamnosus GR1 and Lactobacillus reuteri RC-14 - Bacterial Vaginosis, Premature Birth | Phase 3 | Terminated | Oswaldo Cruz Foundation | 645 | 2006-01-01 | 2011-06-15 |
| Premature Infants in Need of Transfusion (PINT) Red blood cell transfusion - Anemia of Prematurity | Phase 3 | Completed | McMaster University | 424 | 2001-02-01 | 2015-09-24 |
| Beneficial Effects of Antenatal Magnesium Sulfate (BEAM Trial) magnesium sulfate - Cerebral Palsy, Intraventricular Hemorrhage | Phase 3 | Completed | The George Washington University Biostatistics Center | 2136 | 1997-12-01 | 2019-07-12 |
| Antenatal Phenobarbital to Prevent Neonatal Intracranial Hemorrhage Phenobarbital, Saline - Infant, Newborn, Infant, Low Birth Weight | Phase 3 | Completed | NICHD Neonatal Research Network | 610 | 1993-02-01 | 2019-03-22 |
| Magnesium Sulfate to Prevent Brain Injury in Premature Infants magnesium sulfate - Brain Injuries, Cerebral Palsy | Phase 3 | Unknown | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | 1987-08-01 | 2005-06-24 |
Leukomalacia, Periventricular (8) · Premature Birth (5) · Bronchopulmonary Dysplasia (3) · Cerebral Palsy (3) · Intracranial Hemorrhages (3) · Brain Injuries (2) · Abruptio Placentae (1) · Anemia (1) · Cerebral Hemorrhage (1) · Hydrocephalus (1) · Hypotension (1) · Intellectual Disability (1) · Pulmonary Edema (1) · Retinopathy of Prematurity (1) · Sepsis (1)
Brain Diseases (8) · Cardiovascular Diseases (8) · Central Nervous System Diseases (8) · Cerebrovascular Disorders (8) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (8) · Infant, Newborn, Diseases (8) · Infant, Premature, Diseases (8) · Nervous System Diseases (8) · Vascular Diseases (8) · Female Urogenital Diseases and Pregnancy Complications (5) · Obstetric Labor Complications (5) · Obstetric Labor, Premature (5) · Pregnancy Complications (5) · Urogenital Diseases (5)
Magnesium Sulfate (2) · Sodium Chloride (2) · Dopamine (1) · Erythrocyte Transfusion (1) · Erythropoietin (1) · Oxygen (1) · Phenobarbital (1) · Saline Solution (1) · epoetin beta (1)
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (1) · First Affiliated Hospital Xi'an Jiaotong University (1) · McMaster University (1) · NICHD Neonatal Research Network (1) · Oswaldo Cruz Foundation (1) · The George Washington University Biostatistics Center (1) · University College Cork (1) · University of Chicago (1)
United States (5) · Canada (2) · Australia (1) · Belgium (1) · Brazil (1) · China (1) · Czechia (1) · Ireland (1) · United Kingdom (1)
Avroy A. Fanaroff, MD (1) · Barbara J. Stoll, MD (1) · Chad Andersen, MD (1) · Colm O Donnell (1) · David Corcoran (1) · David K. Stevenson, MD (1) · David Millar (1) · David Van Laere (1) · Dwight Rouse, MD (1) · Edward F. Donovan, MD (1) · Elizabeth Asztalos, MD, MSc (1) · Eugene Dempsey (1) · Gerard Pons (1) · Gunnar Naulaers (1) · Haresh Kirpalani, MD, MSc (1)
PMID 10625862, PMID 12114906, PMID 16939737, PMID 18753646, PMID 19117884, PMID 19622997, PMID 20027029, PMID 20591191, PMID 22059409, PMID 25157725, PMID 25534356, PMID 26254839, PMID 27130143, PMID 27187300, PMID 27244862, PMID 31143877, PMID 33627329, PMID 9250849
M01RR000070 (1), M01RR000750 (1), M01RR000997 (1), M01RR006022 (1), M01RR008084 (1), R01HD021453 (1), U01HD019897 (1), U10HD021364 (1), U10HD021385 (1), U10HD021410 (1), U10HD021414 (1), U10HD021415 (1), U10HD027851 (1), U10HD027853 (1), U10HD027856 (1)