14 terminated. 14 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 14 | Terminated 14 |
Follow Emergencies: new trials by email Literature Review of Emergencies trials Research Report on Emergencies
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Acute Migraine Treatment in the ED With Gepants Rimegepant, Zavegepant - Migraine Headaches | Phase 4 | Terminated | Icahn School of Medicine at Mount Sinai | 9 | 2025-06-05 | 2026-04-29 |
| Oral Penicillin Challenge and Allergy De-labeling in Children Amoxicillin 500mg - Penicillin Allergy | Phase 4 | Terminated | Phoenix Children's Hospital | 31 | 2022-09-26 | 2024-06-14 |
| Low-dose KETamine as an Adjunct to MOrphine for Acute Pain in the ED low dose ketamine, Placebo (saline) - Acute Pain, Opioid Use | Phase 4 | Terminated | University of Aarhus | 116 | 2022-05-31 | 2023-09-26 |
| Comparison of Potassium Binders in the ER Polyethylene Glycol 3350, Sodium Polystyrene Sulfonate Oral Suspension [SPS], Patiromer - Acute Hyperkalemia, Oral Potassium Binders | Phase 4 | Terminated | University of California, Irvine | 37 | 2020-10-20 | 2026-04-22 |
| Patiromer Utility as an Adjunct Treatment in Patients Needing Urgent Hyperkalemia Management Patiromer Powder for Oral Suspension [Veltassa], Placebo - Hyperkalemia | Phase 4 | Terminated | Comprehensive Research Associates | 115 | 2020-10-08 | 2023-08-31 |
| Emergency Department Initiated Extended-Release Naltrexone and Case Management for the Treatment of Alcohol Use Disorder Vivitrol (Extended Release Naltrexone) - Alcohol Use Disorder, Substance Use | Phase 4 | Terminated | University of California, San Francisco | 179 | 2020-08-14 | 2023-06-22 |
| Intranasal Versus Intravenous Ketamine for Procedural Sedation in Children With Non-operative Fractures Intravenous Ketamine, Intranasal Ketamine - Trauma, Fractures, Closed | Phase 4 | Terminated | University of Alabama at Birmingham | 40 | 2019-09-09 | 2023-04-20 |
| Hospital Avoidance Strategies for ABSSSI Dalbavancin - Skin Infection | Phase 4 | Terminated | Washington University School of Medicine | 11 | 2019-03-04 | 2022-12-09 |
| MORphine Use in the Fascia Iliaca Compartment Block With UltraSound Levobupivacaine, Placebo, Acetaminophen - Humans, Anesthetics, Local | Phase 4 | Terminated | Zuyderland Medisch Centrum | 55 | 2019-01-28 | 2021-05-06 |
| Oral Olanzapine Versus Haloperidol or Diazepam Olanzapine oro-dispersible 5Mg Tab, Haloperidol 2Mg encapsulated Tab, Diazepam 2Mg encapsulated Tab - Acute Agitation, Behavioural Emergency | Phase 4 | Terminated | The University of Hong Kong | 12 | 2017-09-01 | 2022-11-04 |
| IM Olanzapine Versus Haloperidol or Midazolam Olanzapine, Haloperidol, Midazolam - Acute Agitation, Behavioural Emergency | Phase 4 | Terminated | The University of Hong Kong | 167 | 2014-12-01 | 2022-11-04 |
| Fentanyl for Breakthrough Pain in the Emergency Department Fentanyl Nasal Spray, Hydromorphone PCA, Placebo Nasal Spray - Pain | Phase 4 | Terminated | M.D. Anderson Cancer Center | 3 | 2014-01-10 | 2021-06-29 |
| A Safety and Efficacy Study of Blood Pressure Control in Acute Aortic Emergencies - A Pilot Study (PROMPT) clevidipine. - Aortic Aneurysm, Aortic Disease | Phase 4 | Terminated | Asma Zainab, M.D. | 5 | 2009-11-01 | 2018-08-27 |
| Minimally-Invasive Cardiovascular Hemodynamic Optimization (MiCHO) Versus Early Goal-Directed Therapy (EGDT) in the Management of Septic Shock Esophageal Doppler monitoring - CardioQ, Deltex Inc, Central line with CVP and continuous ScvO2 monitoring - Severe Sepsis, Septic Shock | Phase 4 | Terminated | Loma Linda University | 5 | 2007-06-01 | 2014-06-25 |
Pain (2) · Acute Pain (1) · Agnosia (1) · Alcoholism (1) · Anaphylaxis (1) · Aortic Aneurysm (1) · Aortic Diseases (1) · Aortic Dissection (1) · Cellulitis (1) · Femoral Fractures (1) · Fractures, Bone (1) · Fractures, Closed (1) · Hip Fractures (1) · Hyperkalemia (1)
Disease Attributes (14) · Pathologic Processes (14) · Pathological Conditions, Signs and Symptoms (14) · Neurologic Manifestations (3) · Signs and Symptoms (3) · Infections (2) · Inflammation (2) · Nervous System Diseases (2) · Acute Aortic Syndrome (1) · Alcohol-Related Disorders (1) · Aneurysm (1) · Brain Diseases (1) · Cardiovascular Diseases (1) · Central Nervous System Diseases (1) · Chemically-Induced Disorders (1)
Haloperidol (2) · Olanzapine (2) · patiromer (2) · Acetaminophen (1) · Amoxicillin (1) · Bulk Drugs (1) · Case Management (1) · Central Venous Catheters (1) · Diazepam (1) · Fentanyl (1) · Hydromorphone (1) · Ketamine (1) · Levobupivacaine (1) · Midazolam (1) · Morphine (1)
The University of Hong Kong (2) · Asma Zainab, M.D. (1) · Comprehensive Research Associates (1) · Icahn School of Medicine at Mount Sinai (1) · Loma Linda University (1) · M.D. Anderson Cancer Center (1) · Phoenix Children's Hospital (1) · University of Aarhus (1) · University of Alabama at Birmingham (1) · University of California, Irvine (1) · University of California, San Francisco (1) · Washington University School of Medicine (1) · Zuyderland Medisch Centrum (1)
United States (10) · Hong Kong (2) · Denmark (1) · Netherlands (1)
Asma Zainab, MD (1) · Charles E Murphy IV, MD (1) · Diane E Hindman, MD PharmD (1) · Esther WY Chan, PhD (1) · Faisal Masud, MD (1) · H. Bryant Nguyen, MD (1) · James Statler, MD (1) · Jonathan Schimmel (1) · Judson Barber, MD (1) · Knox H. Todd, MD (1) · Maria Raven, MD (1) · Sanne Postma, MD (1) · Stephen Y Liang, MD (1) · Stine F Galili, MD (1)
PMID 1015603, PMID 11331167, PMID 11331334, PMID 11374619, PMID 11472277, PMID 12411815, PMID 12548273, PMID 12560416, PMID 14622770, PMID 17138203, PMID 17413915, PMID 18686750, PMID 18762870, PMID 19157368, PMID 19174373, PMID 19690943, PMID 22506940, PMID 23569691, PMID 23788067, PMID 23878064, PMID 2589650, PMID 26330019, PMID 26759680, PMID 27714758, PMID 27787895, PMID 33238043, PMID 33681744, PMID 36328851, PMID 37016309, PMID 37308268, PMID 41730555, PMID 9862240
2016 (1)