56 completed, 15 recruiting, 13 unknown, 4 terminated. 18 Not applicable, 15 Phase 1, 9 Phase 2, 7 Phase 4, 3 Phase 3.
Follow Anaphylaxis: new trials by email Literature Review of Anaphylaxis trials Research Report on Anaphylaxis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| FASC: Fish Allergy in Spanish Children - A Study of New Cases of Fish Allergy in Children and Adolescents Fish Allergy, Food Hypersensitivity | Not yet recruiting | Carmelo Escudero | 120 | 2026-10-01 | 2026-07-27 | |
| Post-market Safety Study of LUMISIGHT Hypersensitivity Reactions | Recruiting | Lumicell, Inc. | 1500 | 2026-09-30 | 2026-10-14 | |
| Virtual Reality-Based Simulation Versus High-Fidelity Simulation for Emergency Management Training in Medical Interns Virtual Reality-Based Emergency Simulation, High-Fidelity Simulation - Anaphylaxis, Hypoxia | Not applicable | Active not recruiting | Seoul National University Hospital | 124 | 2026-02-20 | 2026-05-13 |
| Steroid Use in Treatment of Allergic Reactions to Food Antihistamines, Systemic corticosteroids, Adrenaline (rescue medication) - Anaphylactic Reaction, Anaphylaxis | Phase 4 | Recruiting | Johannes Trueck | 160 | 2026-01-26 | 2026-01-27 |
| Comparative PK/PD of FMXIN002 and EpiPen, in Healthy Adults With Allergic Rhinitis FMXIN002 single dose, Epinephrine autoinjector single dose, FMXIN002 single dose + NAC - Anaphylaxis, Allergy | Phase 1 / Phase 2 | Enrolling by invitation | Nasus Pharma | 50 | 2025-11-03 | 2025-11-14 |
| PK/PD Study of IN-001 Sublingual Spray in Healthy Adults Epinephrine Auto-Injector 0.3 mg/0.3 mL, Epinephrine 0.3 mg intramuscular manual injection via a syringe and needle, IN-001 9.06 mg Sublingual Spray - Food Allergy, Anaphylaxis | Phase 1 | Completed | Insignis Therapeutics, Inc. | 32 | 2025-10-24 | 2026-05-05 |
| Effects of Inhaled Epinephrine on Systemic Allergic Reactions During Allergy Testing, Immunotherapy or Oral Challenges Inhaled Epinephrine - Hypersensitivity, Anaphylaxis | Phase 1 | Recruiting | Dr. George Luciuk | 100 | 2025-08-25 | 2026-08-10 |
| Comparison Between a Rush and a Conventional Oral Immunotherapy Protocol to Treat Cow's Milk and Hen´s Egg Allergy. CompITO Study "Rush" regimen, "Conventional" regimen - Food Allergy in Children, Milk Allergy | Phase 2 / Phase 3 | Recruiting | Pablo Rodríguez del Rio | 40 | 2025-06-03 | 2026-02-18 |
| Phase 1 Crossover Study Evaluating the Safety, Tolerability, and Pharmacokinetics of KP001 in Healthy Adult Volunteers KP001, Placebo - Acute Allergic Reaction, Anaphylaxis | Phase 1 | Completed | Kokua Pharma Inc. | 16 | 2025-05-09 | 2025-08-27 |
| Optimizing the Diagnostic Approach to Cephalosporin Allergy Testing Beta-lactam antibiotic (cefazolin, cefuroxime, cefotaxime, ceftazidime, ceftriaxone, cefepime, pre-pen, penicillin G, ampicillin, and histamine) double-blind skin testing, Culprit cephalosporin (cefazolin, ceftazidime, ceftriaxone, cefepime, cephalexin, cefaclor, cefadroxil, cefuroxime, cefpodoxime, cefdinir, or cefixime) double-blind placebo-controlled drug challenge, Similar cephalosporin (cefepime, ceftriaxone, cefaclor, cephalexin, cefixime, or cefdinir) antibiotic double-blind placebo-controlled drug challenge - Drug Allergy, Cephalosporin Allergy | Phase 2 | Recruiting | Massachusetts General Hospital | 300 | 2025-05-05 | 2026-09-04 |
| Diagnosis and Allergen Identification of Perioperative Anaphylaxis Perioperative/Postoperative Complications, Anaphylaxis | Recruiting | Peking University First Hospital | 115 | 2025-01-25 | 2026-06-18 | |
| Analysis of the Role of IgE Proteoforms in Health and Disease Blood sample collection - Anaphylaxis, Mastocytosis | Recruiting | KU Leuven | 200 | 2025-01-01 | 2026-01-09 | |
| Effects of Inhaled Epinephrine on Systemic Allergic Reactions During Allergy Testing Immunotherapy or Oral Challenges Inhaled Epinephrine - Hypersensitivity, Anaphylaxis | Phase 1 | Completed | Dr. George Luciuk | 21 | 2024-07-15 | 2025-07-25 |
| Tolerance in Beekeepers skin prick test, Blood tests - Bee Sting | Recruiting | University Hospital Plymouth NHS Trust | 120 | 2024-01-22 | 2026-09-17 | |
| Study of Inhaled DMC-IH1 and Intramuscular (EpiPen®) Epinephrine in Healthy Male and Female Participants. Epinephrine, Placebo - Anaphylactic Reaction | Phase 1 | Completed | De Motu Cordis | 24 | 2023-10-24 | 2024-08-20 |
| Standardised Drug Provocation Testing in Perioperative Hypersensitivity Full dose DPT with propofol, Full dose DPT with ketamine, Full dose DPT with etomidate - Allergic Reaction, Hypersensitivity | Not applicable | Completed | University Hospital, Antwerp | 50 | 2023-10-23 | 2025-09-08 |
| Comparative Bioavailability of Intranasal Epinephrine A: Epinephrine injection, B: FMXIN002 3.6mg, C: FMXIN002 4.0mg - Anaphylaxis, Anaphylactic Reaction | Phase 1 / Phase 2 | Completed | Nasus Pharma | 12 | 2023-08-22 | 2025-06-18 |
| INhaled Salbutamol vs Placebo for the Treatment of Acute IgE-mediated Abdominal Pain From Allergic Food REactions Salbutamol, Placebo - IgE-mediated Abdominal Pain | Phase 3 | Terminated | Philippe Bégin | 24 | 2023-07-01 | 2025-05-21 |
| A Study About the Use of Omalizumab in the Treatment of Food Allergy and Anaphylaxis Food Hypersensitivity, Anaphylaxis | Completed | Novartis Pharmaceuticals | 62 | 2023-06-01 | 2025-06-18 | |
| Design, Implementation and Evaluation of the Guided Observer Role in Clinical Simulation Educational intervention. observation guide - Anaphylactic Reaction | Not applicable | Completed | Clinica Universidad de Navarra, Universidad de Navarra | 123 | 2023-05-10 | 2024-05-08 |
Showing 20 of 95. Sign in to see all of them.
Hypersensitivity (30) · Food Hypersensitivity (22) · Peanut Hypersensitivity (12) · Drug Hypersensitivity (7) · Hypersensitivity, Immediate (6) · Asthma (4) · Egg Hypersensitivity (4) · Mastocytosis (4) · Emergencies (3) · Hypotension (3) · Milk Hypersensitivity (3) · Nut Hypersensitivity (3) · Angioedema (2) · Bronchial Spasm (2)
Immune System Diseases (94) · Hypersensitivity, Immediate (89) · Hypersensitivity (65) · Nut and Peanut Hypersensitivity (12) · Pathological Conditions, Signs and Symptoms (12) · Chemically-Induced Disorders (10) · Respiratory Tract Diseases (10) · Skin and Connective Tissue Diseases (10) · Skin Diseases (9) · Pathologic Processes (8) · Drug-Related Side Effects and Adverse Reactions (7) · Bronchial Diseases (6) · Lung Diseases (6) · Signs and Symptoms (6) · Cardiovascular Diseases (5)
Epinephrine (11) · Omalizumab (4) · Albuterol (2) · Inhalation (2) · Milk (2) · 2019-nCoV Vaccine mRNA-1273 (1) · Acetaminophen (1) · Allergens (1) · Amoxicillin (1) · Ampicillin (1) · Basophil Degranulation Test (1) · Betamethasone (1) · Blood Specimen Collection (1) · COVID-19 Vaccines (1) · Cefaclor (1)
Assistance Publique - Hôpitaux de Paris (5) · National Institute of Allergy and Infectious Diseases (NIAID) (5) · Central Hospital, Nancy, France (3) · Nasus Pharma (3) · University Hospital, Montpellier (3) · Cambridge University Hospitals NHS Foundation Trust (2) · Charite University, Berlin, Germany (2) · De Motu Cordis (2) · Dr. George Luciuk (2) · Imperial College London (2) · University Hospital, Strasbourg, France (2) · Zhong Wang (2) · Adan Medical Innovation, SL (1) · Algemeen Ziekenhuis Maria Middelares (1) · Amphastar Pharmaceuticals, Inc. (1)
United States (21) · France (17) · Canada (9) · United Kingdom (7) · Australia (4) · Belgium (4) · China (4) · Germany (4) · Spain (3) · Finland (2) · Israel (2) · Italy (2) · Thailand (2) · Turkey (Türkiye) (2) · Austria (1)
George H. Luciuk, MD (2) · Pamela A Frischmeyer-Guerrerio, M.D. (2) · Paul J Turner, FRACP PhD (2) · Zhong Wang, M.D. (2) · Abdelkader Rahmaoui, M.D. (1) · Amy C Plint, MD (1) · Andrew T Clark, MB BD MD (1) · Andrew T Clark, MB BS MD (1) · Arzu Bakirtas (1) · Aurelie Gouel, MD, PhD (1) · Ayca Kiykim (1)
PMID 11061773, PMID 11692118, PMID 12960536, PMID 16461140, PMID 17225722, PMID 18005384, PMID 19226304, PMID 19486033, PMID 19927537, PMID 20004784, PMID 20143649, PMID 21414048, PMID 21749463, PMID 23174658, PMID 23667834, PMID 24239340, PMID 24725226, PMID 24811018, PMID 24811020, PMID 24813248, PMID 25070464, PMID 25215127, PMID 25684279, PMID 25705822, PMID 25705823, PMID 25820033, PMID 26032476, PMID 26095285, PMID 26112147, PMID 26276313, PMID 27297994, PMID 27643438, PMID 28069483, PMID 28884986, PMID 28888253, PMID 28956131, PMID 29040433, PMID 29449164, PMID 29615480, PMID 29759531, PMID 29930853, PMID 30236237, PMID 30288817, PMID 30730977, PMID 30763927, PMID 31035000, PMID 31319102, PMID 31642933, PMID 31676085, PMID 31704438
2017 (2), U01AI184071 (1)