80 completed, 57 unknown, 54 recruiting, 24 not yet recruiting. 99 Not applicable, 6 Phase 3, 6 Phase 4, 5 Phase 2.
Follow Acute Aortic Syndrome: new trials by email Literature Review of Acute Aortic Syndrome trials Research Report on Acute Aortic Syndrome
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| AI-assisted Subtyping-directed Precision Treatment in Acute Aortic Dissection Ulinastatin and Thymalfasin, Ulinastatin - Aortic Aneurysm and Dissection | Not applicable | Not yet recruiting | Nanjing Medical University | 300 | 2027-12-31 | 2026-02-02 |
| A Novel Wire-Reinforced Fenestration of a Hybrid Frozen Elephant Trunk Device for Supra-Aortic Branch Vessel Stenting During Aortic Arch Replacement Modified Supra-Aortic Frozen Elephant Trunk (SA-FET) Device - Aortic Aneurysm, Aortic Dissection | Not applicable | Not yet recruiting | University of Maryland, Baltimore | 100 | 2026-11-01 | 2026-10-21 |
| AAR/AAR+HAR vs AAR+TAR+FET for Type A Aortic Intramural Hematoma Ascending Aorta Replacement / Ascending Aorta Plus Hemiarch Replacement, Ascending Aorta Replacement With Total Arch Replacement and Frozen Elephant Trunk - Aortic Intramural Hematoma | Not applicable | Not yet recruiting | Second Hospital of Jilin University | 400 | 2026-10-01 | 2026-08-13 |
| Outcomes of Left Subclavian Artery Revascularization Strategies During Zone 2 Thoracic Endovascular Aortic Repair Bypass graft - Aortic Aneurysm and Dissection | Not applicable | Not yet recruiting | Assiut University | 50 | 2026-10-01 | 2026-07-13 |
| False Lumen Treatment for Prevention of Aortic Growth Using Shape Memory Polymer - First-in-Human Study (FLAGSHIP_FRA) False Lumen Embolization System, IMPEDE-FX RapidFill - Aortic Dissection | Not applicable | Not yet recruiting | Shape Memory Medical, Inc. | 15 | 2026-10-01 | 2026-01-29 |
| MBA Early Feasibility Study GORE® Multibranch Arch Endoprosthesis, GORE® Ascending Stent Graft - Thoracic Aortic Aneurysm, Penetrating Aortic Ulcers (PAUs) | Not applicable | Recruiting | W.L.Gore & Associates | 20 | 2026-09-02 | 2026-10-01 |
| Retrospective Real-World Data Collection of the Conformable GORE® TAG® Thoracic Endoprosthesis When Used in Frozen Elephant Trunk Procedures for Treatment of Aortic Aneurysms and Dissections Antegrade deployment of covered thoracic aortic stent graft as completion in frozen elephant trunk procedure - Dissection of Aorta, Aneurysm Aortic | Not yet recruiting | W.L.Gore & Associates | 350 | 2026-09-01 | 2026-08-03 | |
| TBE Zone 0/1 PMS in Japan Gore® TAG® Thoracic Aortic Branch Stent Graft System - Aneurysm of Aorta, Thoracic, Dissection of Aorta, Thoracic | Not yet recruiting | W.L.Gore & Associates | 75 | 2026-09-01 | 2026-07-09 | |
| Aortic Dissection Detection Risk Score With D-dimer to Rule-Out Acute Aortic Syndrome D-dimer test - Acute Aortic Syndrome | Recruiting | Chinese University of Hong Kong | 746 | 2026-08-11 | 2026-10-21 | |
| sirA-CPB Strategy Reduces New Ischemic/Embolic Lesions After Acute Type A Aortic Dissection Surgery sirA-CPB strategy, the traditional CPB strategy - Dissection, Aortic | Not applicable | Not yet recruiting | Xiangya Hospital of Central South University | 270 | 2026-07-20 | 2026-08-06 |
| EIT Evaluation of Different Antihypertensive Agents on the Ventilation-Perfusion Ratio in Patients With Acute Respiratory Failure Nitroglycerin, Nicardipine - Acute Respiratory Failure (ARF), Hypertension | Not applicable | Not yet recruiting | First Affiliated Hospital of Wannan Medical College | 12 | 2026-07-15 | 2026-07-02 |
| Guo&Amp;'s Distal Entry Tear Repair With WeFlow-EndoPatch System (Gallant Study) WeFlow-EndoPatch Aortic Endovascular Patch System, Conventional Treatment group - Aortic Dissection, Distal Entry Tear | Not applicable | Recruiting | Hangzhou Endonom Medtech Co., Ltd. | 216 | 2026-07-13 | 2026-08-26 |
| Soft Foam Dressings for Pressure Injury Prevention of Cardiac Surgery CONVAFoam Hydrofiber Dressing, Standard Pressure Injury Prevention Care - CAD - Coronary Artery Disease, CABG | Not applicable | Not yet recruiting | Shih,Wen-Chi | 80 | 2026-05-31 | 2026-05-14 |
| LLM-Based Intelligent Health Management Assistant in Life-Cycle Health Management of Cardiac Surgery Patients LLM-Based Intelligent Health Management Assistant - Coronary Artery Bypass Grafting, Heart Valve Disease | Not applicable | Not yet recruiting | Beijing Anzhen Hospital | 500 | 2026-05-01 | 2026-04-13 |
| The EnvScore-Aorte Diagnostic Study Protocol for the Identification of Acute Aortic Syndrome Acute Aortic Syndrome | Not yet recruiting | Centre Hospitalier Universitaire de Besancon | 580 | 2026-04-01 | 2026-03-12 | |
| False Lumen Treatment for Prevention of Aortic Growth Using Shape Memory Polymer - First-in-Human Study (FLAGSHIP_CHL) False Lumen Embolization System, IMPEDE-FX RapidFill - Aortic Dissection | Not applicable | Not yet recruiting | Shape Memory Medical, Inc. | 15 | 2026-04-01 | 2026-03-19 |
| AI-CARE: Artificial Intelligence for Cardiovascular Analysis and Risk Evaluation Aorta AIM Automated Measurement, Expert Radiologist Manual Measurement - Aortic Aneurysm, Aortic Aneurysm Abdominal | Recruiting | Aiatella Oy | 250 | 2026-03-31 | 2026-04-06 | |
| Effects of Myofascial Release on Cardiac Patients After Median Sternotomy myofascial release+Routine Physical Therapy, Routine Physical therapy - Aortic Aneurysm and Dissection, Coronary Artery Disease (CAD) | Not applicable | Recruiting | Siou-Pin Huang | 50 | 2026-03-25 | 2026-06-16 |
| PregnAncy-Related Aortic DISsEction in China Intervention strategies including medication or surgery - Pregnancy Complication, Aortic Dissection | Recruiting | DeltaHealth Hospital · Shanghai | 500 | 2026-03-17 | 2026-07-17 | |
| Nutritional Ketosis Marfan Ketogenic diet - Marfan Syndrome, Aortic Dissection | Not applicable | Not yet recruiting | Washington University School of Medicine | 15 | 2026-03-13 | 2026-03-27 |
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Aortic Dissection (204) · Aortic Aneurysm (46) · Aortic Aneurysm, Thoracic (43) · Dissection, Thoracic Aorta (30) · Aortic Diseases (26) · Penetrating Atherosclerotic Ulcer (24) · Aneurysm (21) · Cardiovascular Diseases (13) · Aneurysm, Aortic Arch (11) · Vascular Diseases (11) · Aortic Aneurysm, Thoracoabdominal (9) · Dissection, Ascending Aorta (8) · Heart Valve Diseases (8) · Marfan Syndrome (8)
Vascular Diseases (248) · Cardiovascular Diseases (246) · Dissection, Blood Vessel (235) · Aortic Diseases (233) · Aneurysm (224) · Aortic Aneurysm (53) · Pathological Conditions, Signs and Symptoms (35) · Aortic Dissection (31) · Arterial Occlusive Diseases (31) · Arteriosclerosis (30) · Pathologic Processes (30) · Heart Diseases (28) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (18) · Aortic Aneurysm, Thoracic (16)
Endovascular Aneurysm Repair (14) · Surgical Procedures, Operative (6) · urinastatin (4) · Sodium Chloride (3) · Genetic Testing (2) · Magnetic Resonance Imaging (2) · Methylprednisolone (2) · Movement (2) · Pharmaceutical Preparations (2) · Saline Solution (2) · Thymalfasin (2) · clevidipine (2) · Angioplasty (1) · Annexins (1) · Atenolol (1)
W.L.Gore & Associates (12) · Nanjing Medical University (10) · Beijing Anzhen Hospital (7) · Qilu Hospital of Shandong University (7) · First Affiliated Hospital Xi'an Jiaotong University (6) · Vascutek Ltd. (6) · Xijing Hospital (6) · Cook Research Incorporated (5) · Hangzhou Endonom Medtech Co., Ltd. (5) · Lifetech Scientific (Shenzhen) Co., Ltd. (5) · Bolton Medical (4) · Chinese University of Hong Kong (4) · First Affiliated Hospital of Zhejiang University (4) · JOTEC GmbH (4) · Shanghai Zhongshan Hospital (4)
China (72) · United States (57) · Italy (27) · France (26) · Germany (25) · United Kingdom (21) · Netherlands (11) · Spain (9) · Sweden (8) · Canada (7) · Denmark (7) · Austria (6) · Brazil (6) · Japan (6) · Belgium (5)
Hong Liu (3) · Joseph Lombardi, MD (3) · Yang Yan (3) · Boris Akselrod, Professor (2) · Eric Roselli, MD (2) · Francesco Nappi (2) · Fulvio Morello, MD, PhD (2) · Hong-jia Zhang, MD (2) · Karl Illig, MD (2) · WeiPing Cheng, master (2) · Wilson Szeto, MD (2) · Xin Zhao (2) · Yon Hee Shim (2) · Yong-feng Shao (2)
PMID 37059239, PMID 38989575, PMID 39963789, PMID 26088302, PMID 30401530, PMID 32599034, PMID 34468733, PMID 36001309, PMID 36912033, PMID 37330702, PMID 26205591, PMID 29030346, PMID 31220387, PMID 42729155, PMID 10332016, PMID 10685714, PMID 12727160, PMID 13577293, PMID 15364869, PMID 15696036, PMID 16227309, PMID 16533689, PMID 16533690, PMID 16872959, PMID 17850909, PMID 18573403, PMID 18805213, PMID 19457832, PMID 19542407, PMID 19996018, PMID 20173125, PMID 20625143, PMID 20858819, PMID 20860678, PMID 20952217, PMID 21345636, PMID 21764338, PMID 21969019, PMID 22062792, PMID 22406748, PMID 22891838, PMID 22965999, PMID 23599348, PMID 23622922, PMID 23809203, PMID 23885677, PMID 23922146, PMID 24304053, PMID 24604712, PMID 24685375
2019 (1), U01HL068270 (1), UL1TR001082 (1)