4 completed, 2 recruiting, 1 enrolling by invitation. 2 Phase 2, 1 Early Phase 1, 1 Not applicable, 1 Phase 1, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 2 | Completed 1, Enrolling by invitation 1 |
| Early Phase 1 | 1 | Completed 1 |
| Not applicable | 1 | Recruiting 1 |
| Phase 1 | 1 | Recruiting 1 |
| Phase 4 | 1 | Completed 1 |
Follow Trihexyphenidyl: new trials by email Literature Review of Trihexyphenidyl trials Research Report on Trihexyphenidyl
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparison of Benzhexol and Procyclidine for Tremor in Tremor-Predominant Parkinson's Disease Benzhexol, Procyclidine - Parkinson Disease (PD) | Not applicable | Recruiting | safia bano | 88 | 2026-09-01 | 2026-09-14 |
| Accelerating TMS for Cervical Dystonia Transcranial Magnetic Stimulation (TMS), Placebo, trihexyphenidyl 10mg - Isolated Cervical Dystonia | Phase 2 | Enrolling by invitation | Duke University | 50 | 2024-12-17 | 2026-06-10 |
| Pharmacogenomic Contributions to Trihexyphenidyl Biotransformation and Response in Children With Dystonic Cerebral Palsy Trihexyphenidyl - Pediatric Disorder, Genetic Predisposition | Phase 1 | Recruiting | Children's Mercy Hospital Kansas City | 40 | 2024-10-15 | 2026-06-24 |
| a Pilot Study of Pramipexole to Treat Extrapyramidal Symptoms Induced by Antipsychotics Pramipexole, Trihexyphenidyl hydrochloride - Extrapyramidal Syndrome | Early Phase 1 | Completed | Shanghai Mental Health Center | 50 | 2018-05-01 | 2022-06-27 |
| Neuroimaging of Dystonia Primary Cervical Dystonia (Trihexyphenidyl), Controls Primary Cervical Dystonia (Trihexyphenidyl), DYT 1 Dystonia (Healthy Control) - Primary Cervical Dystonia, DYT 1 Dystonia | Completed | University of Florida | 20 | 2014-05-01 | 2017-12-22 | |
| Excessive Crying in Children With Cerebral Palsy and Communication Deficits Placebo, Baclofen, Diazepam, Clonazepam, Trihexyphenidyl, Tetrabenazine, Gabapentin, Topiramate, Lamotrigine, Amitriptyline. - Cerebral Palsy, Excessive Crying | Phase 4 | Completed | Sathbhavana Brain Clinic | 131 | 2005-12-07 | 2021-10-28 |
| Childhood Hypertonia of Central Origin: A Trial of Anticholinergic Treatment Effects trihexyphenidyl - Dystonia | Phase 2 | Completed | University of Southern California | 35 | 2003-01-01 | 2014-05-23 |
Cerebral Palsy (3) · Dystonia (3) · Dystonic Disorders (2) · Basal Ganglia Diseases (1) · Cervical Dystonia, Primary (1) · Deglutition Disorders (1) · Dystonia Musculorum Deformans (1) · Dystonia musculorum deformans type 1 (1) · Genetic Predisposition to Disease (1) · Hyperalgesia (1) · Muscle Spasticity (1) · Neoplasm Metastasis (1) · Neuralgia (1) · Pain (1) · Parkinson Disease (1)
Children's Mercy Hospital Kansas City (1) · Duke University (1) · Sathbhavana Brain Clinic (1) · Shanghai Mental Health Center (1) · University of Florida (1) · University of Southern California (1) · safia bano (1)
United States (4) · China (1) · Pakistan (1)
David Vaillancourt, PhD (1) · Huafang Li, MD,Phd (1) · Michael Okun, MD (1) · Nagabhushana Rao Potharaju, BScMDDCHDM (1) · Noreen Bukhari-Parlakturk, MD PhD (1) · Rose Gelineau-Morel, MD (1) · Terence D Sanger, MD, PhD (1)