7 completed, 1 active not recruiting, 1 recruiting, 1 unknown. 10 Phase 1, 5 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 10 | Completed 7, Active not recruiting 1, Recruiting 1, Unknown 1 |
| Phase 2 | 5 | Completed 4, Active not recruiting 1 |
Follow Dystonic Disorders: new trials by email Literature Review of Dystonic Disorders trials Research Report on Dystonic Disorders
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pharmacogenomic Contributions to Trihexyphenidyl Biotransformation and Response in Children With Dystonic Cerebral Palsy Trihexyphenidyl - Pediatric Disorder, Genetic Predisposition | Phase 1 | Recruiting | Children's Mercy Hospital Kansas City | 40 | 2024-10-15 | 2026-06-24 |
| An Open-label Study to Define the Safety, Tolerability and Clinical Activity of Deutetrabenazine (AUstedo) in Adult Study Subjects With DYsTonia Deutetrabenazine 6 MG - Dystonia, Primary | Phase 1 / Phase 2 | Completed | University of Pennsylvania | 15 | 2021-04-29 | 2024-09-20 |
| Deep Brain Stimulation Surgery for Focal Hand Dystonia DBS surgery, Medtronic Activa Rechargeable System - Dystonia, Focal Dystonia | Phase 1 / Phase 2 | Active not recruiting | National Institute of Neurological Disorders and Stroke (NINDS) | 5 | 2018-01-17 | 2026-11-05 |
| Electrophysiological and Neuroimaging Correlates of the Effect of Zolpidem in Patients With Focal Dystonia Zolpidem, Placebo - Focal Dystonia | Phase 1 | Completed | University Medical Centre Ljubljana | 24 | 2017-09-30 | 2023-12-04 |
| Multi-Target Pallidal and Thalamic Deep Brain Stimulation for Hemi-Dystonia Deep Brain Stimulation - Dystonia, Dystonia, Secondary | Phase 1 | Unknown | University of British Columbia | 4 | 2015-01-01 | 2020-11-02 |
| Pilot Trial of Botulinum Toxin and Occupational Therapy for Writer's Cramp BoNT Injections, Occupational Therapy - Dystonia | Phase 1 / Phase 2 | Completed | National Institute of Neurological Disorders and Stroke (NINDS) | 13 | 2013-12-03 | 2018-03-20 |
| rTMS and Retraining in Focal Hand Dystonia Repetitive Transcranial Magnetic Stimulation, Sensorimotor Retraining, Non-specific Therapy - Focal Dystonia | Phase 1 / Phase 2 | Completed | University of Minnesota | 9 | 2011-11-01 | 2019-11-18 |
| A Study of Acetyl Hexapeptide-8 (AH8) in Treatment of Blepharospasm Acetyl-Hexapeptide Topical Treatment, placebo - Focal Dystonia | Phase 1 / Phase 2 | Completed | National Institute of Neurological Disorders and Stroke (NINDS) | 24 | 2009-07-01 | 2012-09-06 |
| Repetitive Transcranial Magnetic Stimulation for the Treatment of Focal Hand Dystonia rTMS, Sham rTMS - Dystonia, Focal, Task-specific | Phase 1 | Completed | University of Minnesota | 17 | 2008-07-01 | 2016-06-17 |
| Motor and Premotor Cortex Stimulation for Treatment of Secondary Focal Dystonia With Striato Palliadal Lesion : Evaluation of Safety and Effectiveness Implantation of neurostimulators and their auxiliary components - Focal Dystonia | Phase 1 | Completed | University Hospital, Clermont-Ferrand | 5 | 2007-09-01 | 2014-07-08 |
Dystonia (5) · Dystonia, Focal, Task-Specific (3) · Blepharospasm (1) · Cerebral Palsy (1) · Genetic Predisposition to Disease (1)
Central Nervous System Diseases (10) · Movement Disorders (10) · Nervous System Diseases (10) · Dyskinesias (5) · Neurologic Manifestations (5) · Pathological Conditions, Signs and Symptoms (5) · Signs and Symptoms (5) · Brain Damage, Chronic (1) · Brain Diseases (1) · Disease Attributes (1) · Disease Susceptibility (1) · Eye Diseases (1) · Eyelid Diseases (1) · Pathologic Processes (1)
Deep Brain Stimulation (1) · Massage (1) · Occupational Therapy (1) · Transcranial Magnetic Stimulation (1) · Transcutaneous Electric Nerve Stimulation (1) · Trihexyphenidyl (1) · Zolpidem (1) · deutetrabenazine (1)
National Institute of Neurological Disorders and Stroke (NINDS) (3) · University of Minnesota (2) · Children's Mercy Hospital Kansas City (1) · University Hospital, Clermont-Ferrand (1) · University Medical Centre Ljubljana (1) · University of British Columbia (1) · University of Pennsylvania (1)
United States (7) · Canada (1) · Serbia (1) · Slovenia (1)
Teresa J Kimberley, PhD, PT (2) · Chris Honey, MD,DPhil,FRCSC (1) · Debra J Ehrlich, M.D. (1) · Mark Hallett, M.D. (1) · Rose Gelineau-Morel, MD (1)
M01RR000400 (1)