45 completed, 7 recruiting, 6 unknown, 5 withdrawn. 69 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 69 | Completed 45, Recruiting 7, Unknown 6, Withdrawn 5, Not yet recruiting 4, Active not recruiting 1, Terminated 1 |
Follow Duodenal Diseases: new trials by email Literature Review of Duodenal Diseases trials Research Report on Duodenal Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Vonoprazan High-Dose Dual VS Levofloxacin Concomitant Vonoprazan, Levofloxacin 500mg - Helicobacter Pylori Infection, Peptic Ulcer Disease | Phase 4 | Not yet recruiting | Damascus Hospital | 150 | 2026-11-01 | 2026-06-03 |
| PPI Dosing Per CYP2C19 Genotype CYP2C19 based dosing Proton Pump Inhibitors, Conventional proton pump inhibitor dose - Gastroesophageal Reflux Disease With Esophagitis | Phase 4 | Not yet recruiting | University of Florida | 200 | 2026-10-01 | 2026-09-28 |
| Esomeprazole Plus Sucralfate for Post-ESD Ulcer Healing Esomeprazole (Intravenous), Esomeprazole (Oral), Sucralfate Suspension - Early Gastric Cancer, Gastric Dysplasia | Phase 4 | Not yet recruiting | LanZhou University | 120 | 2026-04-20 | 2026-03-23 |
| Vonoprazan-based Versus Esomeprazole-based Triple Therapy for Helicobacter Pylori Eradication vonoprazan-based triple therapy (VAL regimen), Esomeprazole-based triple therapy (EAL regimen) - Helicobacter Pylori Infection, Dyspepsia | Phase 4 | Completed | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | 80 | 2026-04-15 | 2026-10-26 |
| Saccharomyces Boulardii Combined With Bismuth Quadruple Therapy for Helicobacter Pylori Rescue Treatment Bismuth, Esomeprazole, Tetracycline - Gastritis, Dyspepsia | Phase 4 | Recruiting | Yongquan Shi | 1248 | 2025-10-28 | 2025-12-02 |
| Preventing Postoperative Complications in Patients Undergoing High-risk Pancreatoduodenectomy With a Bundle Approach Including Hydrocortisone, Octreotide, and the Teres Ligament Patch (PANENCA) HOP bundle - Pancreas Head Cancer, Pancreas Adenocarcinoma | Phase 4 | Recruiting | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 400 | 2025-09-01 | 2025-12-22 |
| CURE-H. Pylori: A Trial on the Combination of Anti-Ulcerants and Levofloxacin-Based Therapy for Helicobacter Pylori Eradication Arm 1: Dexlansoprazole + Levofloxacin-Based Triple Therapy, Arm 2: Lansoprazole + Levofloxacin-Based Triple Therapy, Arm 3: Vonoprazan + Levofloxacin-Based Triple Therapy - H. Pylori Gastrointestinal Disease, H.Pylori Infection | Phase 4 | Recruiting | Dow University of Health Sciences | 942 | 2025-05-01 | 2026-01-15 |
| Efficacy Comparison of Vonoprazan Combined With Different Antibiotics in Dual Therapy for Helicobacter Pylori Eradication: A Prospective, Randomized Controlled Clinical Trial Vonoprazan, Tetracycline 500mg tid, Minocycline - Gastritis, Indigestion, Helicobacter Pylori Infection, Gastric Cancer, Peptic Ulcer | Phase 4 | Recruiting | Yongquan Shi | 400 | 2025-04-01 | 2025-08-14 |
| Efficacy and Safety of Vonorasan Versus Esomeprazole in the Treatment of Ulcers After Endoscopic Submucosal Dissection Vonoprazan, Esomeprazole - Ulcers, Gastric | Phase 4 | Not yet recruiting | Shicai Ye | 196 | 2024-08-01 | 2024-07-29 |
| Comparative Effectiveness of Triple Versus Quadruple Therapy in the Treatment of Helicobacter Pylori Induced Gastritis Triple Therapy, Quadruple Therapy - Helicobacter Pylori Infection, Chronic Gastritis | Phase 4 | Completed | Azfar Farogh | 752 | 2024-01-05 | 2025-12-31 |
| The Bioavailability and Effect on Pouch pH of Esomeprazole After Gastric Bypass upper endoscopy - Obesity, Gastric Reflux | Phase 4 | Recruiting | Prof Urs Zingg | 50 | 2023-11-01 | 2026-06-09 |
| Jinghua Weikang Capsule in the Treatment of Reflux Esophagitis jinghua weikang capsule - Reflux Esophagitis | Phase 4 | Unknown | The First Affiliated Hospital of Dalian Medical University | 260 | 2023-10-01 | 2023-09-28 |
| OPEN Versus InTact Capsule Proton Pump Inhibitors for the Treatment of Marginal Ulcers Omeprazole 40 milligrams - Marginal Ulcer | Phase 4 | Recruiting | Stephen Firkins | 122 | 2023-03-14 | 2026-03-19 |
| Tranexamic Acid During Upper GI Endoscopic Resection Procedures Tranexamic acid, Epinephrine injection - Gastric Polyp, Gastric Neoplasm | Phase 4 | Unknown | Assaf-Harofeh Medical Center | 200 | 2023-02-01 | 2023-08-09 |
| The Use of Indocyanine Green to Visualize Blood Flow to the Gastrojejunostomy During Bariatric Surgery. Indocyanine green, Stryker 1688 AIM system - Ulcer, Gastric, Obesity, Morbid | Phase 4 | Active not recruiting | University Health Network, Toronto | 300 | 2023-01-25 | 2025-10-16 |
| Effects of High-dose Dual Therapy and Bismuth Quadruple Therapy for Helicobacter Pylori Eradication on Intestinal Microecology Esomeprazole, Amoxicillin, Bismuth - Gastritis, Dyspepsia | Phase 4 | Completed | Xijing Hospital of Digestive Diseases | 124 | 2022-12-01 | 2025-07-03 |
| Hypoxia During Gastroenterological Endoscope Procedures Sedated With Ciprofol In Overweight Or Obesity Patients Ciprofol, Propofol - Gastric Ulcer, Gastric Cancer | Phase 4 | Completed | RenJi Hospital | 1090 | 2022-09-08 | 2024-06-07 |
| Compare the Effect of Eupatilin and Rebamipide on the Prevention of Gastroenteropathy Eupatilin, Rebamipide - Rheumatoid Arthritis, Osteoarthritis | Phase 4 | Unknown | Seoul National University Boramae Hospital | 50 | 2021-06-01 | 2021-05-13 |
| Potassium-Competitive Acid Blocker Versus pROton-Pump Inhibitor for GastroproTECTion Strategies In Patients at High Gastro-Intestinal Bleeding Risk Receiving Antithrombotic Therapy PPI, P-CAB 50 - Coronary Artery Disease, Percutaneous Coronary Intervention | Phase 4 | Recruiting | Duk-Woo Park, MD | 3320 | 2021-05-12 | 2026-08-28 |
| Helicobacter Rescue Therapy With High-dose Esomeprazole and Amoxicillin Dual Therapy Versus Bismuth-containing Quadruple Therapy Esomeprazole, Amoxicillin, Bismuth - Gastritis, Dyspepsia | Phase 4 | Completed | Xijing Hospital of Digestive Diseases | 658 | 2020-12-20 | 2023-01-31 |
Showing 20 of 69. Sign in to see all of them.
Peptic Ulcer (36) · Stomach Ulcer (15) · Gastritis (12) · Dyspepsia (11) · Esophagitis, Peptic (9) · Stomach Neoplasms (9) · Duodenal Ulcer (7) · Gastroesophageal Reflux (5) · Peptic Ulcer Hemorrhage (5) · Gastrointestinal Hemorrhage (4) · Duodenal Neoplasms (3) · Hemorrhage (2) · Obesity (2) · Acute Coronary Syndrome (1) · Arthritis, Rheumatoid (1)
Digestive System Diseases (69) · Gastrointestinal Diseases (69) · Intestinal Diseases (69) · Stomach Diseases (67) · Peptic Ulcer (30) · Pathological Conditions, Signs and Symptoms (28) · Gastroenteritis (22) · Signs and Symptoms (15) · Pathologic Processes (13) · Digestive System Neoplasms (12) · Gastrointestinal Neoplasms (12) · Neoplasms (12) · Neoplasms by Site (12) · Signs and Symptoms, Digestive (12)
Amoxicillin (15) · Esomeprazole (14) · Bismuth (11) · Clarithromycin (10) · Omeprazole (9) · Lansoprazole (7) · Famotidine (5) · Rabeprazole (5) · 1-(5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine (4) · Furazolidone (4) · Pantoprazole (4) · Tetracycline (4) · Berberine (3) · Metronidazole (3) · Proton Pump Inhibitors (3)
Xijing Hospital of Digestive Diseases (7) · AstraZeneca (3) · Shanghai Jiao Tong University School of Medicine (3) · Chinese University of Hong Kong (2) · Damascus Hospital (2) · Eisai Co., Ltd. (2) · Far Eastern Memorial Hospital (2) · Kaohsiung Veterans General Hospital. (2) · Yongquan Shi (2) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Assaf-Harofeh Medical Center (1) · Azfar Farogh (1) · Bakirkoy Dr. Sadi Konuk Research and Training Hospital (1) · Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh (1) · Boston Children's Hospital (1)
China (23) · United States (9) · South Korea (6) · Taiwan (6) · Japan (4) · Netherlands (2) · Pakistan (2) · Switzerland (2) · Syria (2) · Bangladesh (1) · Canada (1) · Denmark (1) · Finland (1) · Greece (1) · Iran (1)
Yongquan Shi, Ph. D (4) · Hong Lu, M.D. (2) · Allan Okrainec (1) · Anders Perner, MD, PhD (1) · Anton Bermont, MD (1) · Antone R Opekun, PA-C (1) · Ben D Albert, MD (1) · Byeong Ug Kim (1) · C. Mel Wilcox, M.D. (1) · Ching-Kuan Liu, MD, PhD (1) · Dae Young Cheung, professor (1) · David Y Graham, MD (1) · Deng-Chyang Wu, MD PhD (1) · Diansan Su (1) · Eun Jung Jeon (1)
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