33 completed, 12 terminated, 10 unknown, 3 recruiting. 26 Not applicable, 12 Phase 2, 6 Phase 4, 4 Phase 3, 3 Phase 1.
Follow Diastolic Heart Failure: new trials by email Literature Review of Diastolic Heart Failure trials Research Report on Diastolic Heart Failure
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| GLP-1/GIP Receptor Agonists in Obesity-Related HFpEF: The GLIDE-HF Registry GLP-1 / GIP receptor agonist - Heart Failure With Preserved Ejection Fraction, Obesity | Not yet recruiting | Miedziowe Centrum Zdrowia SA | 150 | 2027-01-01 | 2026-08-26 | |
| Heart Failure and Postoperative Outcome in Surgery - a National Registry Study Heart Failure, Diastolic Heart Failure | Not yet recruiting | Umeå University | 2200000 | 2026-08-01 | 2026-06-09 | |
| Left Ventricular Reverse Remodeling Evaluation After Surgical Correction of Aortic Regurgitation Not applicable - observational study - Aortic Valve Regurgitation, Mitral Valve Regurgitation | Recruiting | Petrovsky National Research Centre of Surgery | 120 | 2024-05-09 | 2025-06-11 | |
| Prevention of Age-associated Cardiac and Vascular Dysfunction Using Avmacol ES Sulforaphane - Diastolic Dysfunction, Systolic Dysfunction | Phase 1 / Phase 2 | Withdrawn | Texas Tech University Health Sciences Center | 2022-07-01 | 2026-06-29 | |
| Parasympathetic Augmentation Via Respiratory Training for Patients With Systolic Heart Failure Meo Health Breathing and humming exercises - Diastolic Heart Failure | Not applicable | Terminated | Lancaster General Hospital | 65 | 2022-02-07 | 2025-10-23 |
| Assessment of CCM in HF With Higher Ejection Fraction Cardiac Contractility Modulation Therapy via OPTIMIZER™ Smart Mini System, OPTIMIZER™ Smart Mini System - Heart Failure, Heart Failure With Preserved Ejection Fraction | Not applicable | Recruiting | Impulse Dynamics | 1500 | 2022-02-03 | 2026-10-23 |
| Investigating Multimodally Endothelial Dysfunction in Ocular and Systemic Disease Optical coherence tomography(-angiography) OCT(A), Fundus pictures, DVA 3.0 - Kidney Diseases, Diastolic Heart Failure | Not applicable | Unknown | Universitaire Ziekenhuizen KU Leuven | 1000 | 2021-07-06 | 2024-07-03 |
| Effects of Postural Balance Exercises in Patients With Heart Failure Core stabilization group(CSG), Wobble board group (WBG) - Heart Failure, Systolic Heart Failure | Not applicable | Completed | Giresun University | 42 | 2021-06-15 | 2023-01-31 |
| Diastolic dYsfunctioN AssessMent in critICally Ill Patients Bedside Echocardiography, Spontaneuos breathing trial, Bedside Echocardiography_1 - Critical Illness, Diastolic Dysfunction | Unknown | Humanitas Clinical and Research Center | 297 | 2021-06-01 | 2022-01-03 | |
| Treatment Of Atrial Fibrillation In Preserved Cardiac Function Heart Failure Catheter ablation, Rate or Rhythm control antiarrhythmic drugs for atrial fibrillation, Insertion of CardioMems Hemodynamic monitor - Atrial Fibrillation, Heart Failure | Phase 4 | Unknown | Electrophysiology Research Foundation | 360 | 2020-07-26 | 2024-05-23 |
| 2 New Measurements Used to Describe the Filling Phase of the Left Ventricle (LV). Diastolic Heart Failure, Left Ventricular Diastolic Dysfunction | Completed | AdventHealth | 111 | 2019-10-30 | 2023-06-29 | |
| Personalized Pacing: A New Paradigm for Patients With Diastolic Dysfunction or Heart Failure With Preserved Ejection Fraction Adjustment of lower rate limit, Maintenance of lower rate limit - Pacemaker, Diastolic Dysfunction | Not applicable | Completed | University of Vermont | 123 | 2019-07-17 | 2022-02-09 |
| Purinergic Signaling and the Postmenopausal Heart Gender - Diastolic Heart Failure, Heart Failure With Preserved Ejection Fraction | Recruiting | Beth Israel Deaconess Medical Center | 500 | 2019-07-01 | 2026-03-20 | |
| Cardiac Resynchronisation Therapy Versus Rate-responsive Pacing in Heart Failure With Preserved Ejection Fraction Biventricular pacemaker - Diastolic Heart Failure | Not applicable | Completed | Cardiff and Vale University Health Board | 10 | 2017-11-27 | 2023-06-02 |
| CMR Exercise Stress Testing in HFpEF stress CMR - Diastolic Heart Failure | Not applicable | Completed | University of Göttingen | 75 | 2017-08-16 | 2020-11-16 |
| Pedometer-Based Walking Intervention in Patients With Chronic Heart Failure With Preserved Ejection Fraction Walking intervention - Diastolic Heart Failure | Not applicable | Unknown | Charles University, Czech Republic | 200 | 2017-04-11 | 2018-05-17 |
| ST2 for the Management of Heart Failure - STADE-HF Conventional strategy, ST2-guided strategy - Heart Failure, Diastolic Heart Failure | Not applicable | Completed | University Hospital, Montpellier | 123 | 2017-01-19 | 2026-06-12 |
| Positive Airway Pressure Therapy Study in Sleep Apnea and Diastolic Heart Failure Adaptive servo ventilation (ASV) - Diastolic Heart Failure | Not applicable | Terminated | ResMed | 2 | 2016-03-01 | 2017-04-17 |
| Myocardial Perfusion, Oxidative Metabolism, and Fibrosis in HFpEF regadenoson - Heart Failure, Diastolic, Diastolic Heart Failure | Phase 4 | Completed | Marvin W. Kronenberg, M.D. | 55 | 2015-11-01 | 2021-02-02 |
| Manipal Heart Failure Registry (MHFR) Heart Failure, Systolic Heart Failure | Unknown | Manipal University | 500 | 2015-09-10 | 2017-05-19 |
Showing 20 of 63. Sign in to see all of them.
Heart Failure, Diastolic (63) · Heart Failure (25) · Heart Failure, Systolic (6) · Hypertension (5) · Hypertension, Pulmonary (4) · Atrial Fibrillation (2) · Depression (2) · Acute Coronary Syndrome (1) · Aortic Valve Insufficiency (1) · Autonomic Nervous System Diseases (1) · Cardiomyopathies (1) · Cardiovascular Diseases (1) · Cerebrovascular Disorders (1) · Coronary Artery Disease (1) · Coronary Disease (1)
Cardiovascular Diseases (62) · Heart Diseases (62) · Heart Failure (38) · Vascular Diseases (11) · Pathological Conditions, Signs and Symptoms (7) · Respiratory Tract Diseases (5) · Hypertension (4) · Lung Diseases (4) · Pathologic Processes (4) · Signs and Symptoms (4) · Behavior (3) · Arrhythmias, Cardiac (2) · Behavioral Symptoms (2) · Disease Attributes (2) · Metabolic Diseases (2)
Spironolactone (3) · Atorvastatin (2) · Blood Specimen Collection (2) · Diet, Sodium-Restricted (2) · Dietary Approaches To Stop Hypertension (2) · Eplerenone (2) · High-Intensity Interval Training (2) · Ranolazine (2) · alagebrium (2) · Anthocyanins (1) · Anti-Arrhythmia Agents (1) · Antioxidants (1) · Cardiac Resynchronization Therapy Devices (1) · Catheter Ablation (1) · Flavonoids (1)
University of Michigan (4) · St Vincent's University Hospital, Ireland (2) · Texas Tech University Health Sciences Center (2) · University of Göttingen (2) · AdventHealth (1) · Arizona State University (1) · Assistance Publique - Hôpitaux de Paris (1) · Beth Israel Deaconess Medical Center (1) · CES University (1) · CVRx, Inc. (1) · Cardiff and Vale University Health Board (1) · Cardiovascular Clinical Sciences Inc (1) · Central Hospital, Nancy, France (1) · Charles University, Czech Republic (1) · CorAssist Cadiovascular Ltd. (1)
United States (28) · Germany (5) · France (3) · India (2) · Ireland (2) · Switzerland (2) · United Kingdom (2) · Austria (1) · Belgium (1) · Brazil (1) · Canada (1) · Colombia (1) · Czechia (1) · Israel (1) · Italy (1)
Scott L Hummel, MD MS (2) · Ajit Singh, PHARM D, PhD (1) · Andrea Natale, MD (1) · Andreas Schuster, MD, PhD (1) · Anthony DeMaria, MD (1) · Antonio Messina, PhD (1) · Bertram Pitt, MD (1) · Christian Seiler, Prof (1) · Dalane W. Kitzman, MD (1) · Dermot J McCaffrey, MB MRCPI FRACP (1) · George Mak, MB MRCPI (1) · Goo-Yeong Cho, MD, PhD (1)
PMID 19850207, PMID 21538388, PMID 21709061, PMID 21869636, PMID 23033371, PMID 23108436, PMID 23500307, PMID 23671819, PMID 23883653, PMID 23985432, PMID 24331202, PMID 24621836, PMID 24720918, PMID 25190739, PMID 25282032, PMID 25398313, PMID 25495811, PMID 26497755, PMID 26635076, PMID 26941415, PMID 27927683, PMID 28673328, PMID 29550319, PMID 30371285, PMID 31273863, PMID 31964186, PMID 32063068, PMID 32168423, PMID 32434700, PMID 32831121, PMID 33472397, PMID 34046195, PMID 36423376, PMID 36691723, PMID 36723919, PMID 36842486, PMID 36897745, PMID 37980262, PMID 38124404, PMID 38170248, PMID 38431079, PMID 38471649, PMID 38614379, PMID 39012942, PMID 39145733, PMID 39900615, PMID 40439171, PMID 40864451
K23GM112014 (1), R01AG018915 (1), R01HL104018 (1)