13 completed, 3 unknown, 2 active not recruiting, 2 withdrawn. 15 Not applicable, 3 Phase 2, 3 Phase 4, 1 Phase 1.
Follow Flavonoids: new trials by email Literature Review of Flavonoids trials Research Report on Flavonoids
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| GreenArt: Nutrikinetics and Bioavailability Studies GreenArt D is a baccharis-type propolis powder extract containing phenolic compounds such as prenylated phenylpropanoids derived from hydroxycinnamic acids and flavonoids., GreenArt 4D is a baccharis-type propolis powder extract containing phenolic compounds such as prenylated phenylpropanoids derived from hydroxycinnamic acids and flavonoids., Placebo - Nutrition, Healthy | Not applicable | Not yet recruiting | Fytexia | 10 | 2026-06-01 | 2026-07-02 |
| In Vitro and in Vivo Evaluation of the Anti-Inflammatory and Antithrombotic Synergy of Vitamin C and Bioflavonoids in Healthy Subjects High Dose of Vitamin C with ir without 50 mg of flavonoids - Cardio-protection | Not applicable | Completed | Democritus University of Thrace | 20 | 2024-10-01 | 2025-07-11 |
| The Efficacy of Aescin in Combination With MPFF in the Early Control of Bleeding From Acute Internal Hemorrhoids, A Randomized Controlled Trial Aescin in Horse Chestnut, Flavonoid - Anorectal Disorder | Not applicable | Unknown | Chiang Mai University | 60 | 2024-04-01 | 2024-04-12 |
| Effects of Cacao Flavonoids in Long COVID-19 Patients (FLALOC) Flavonoids - Long Covid19, Fatigue Syndrome, Chronic | Not applicable | Completed | Guillermo Ceballos Reyes | 46 | 2023-08-01 | 2024-10-01 |
| Effects of Bioflavanoids on Vascular Wall Remodeling in Patients With Varicose Veins "Venarus®" (diosmin and hesperidin), Endovenous laser ablation (EVLA) with miniphlebectomy, Elastic compression - Varicose Veins of Lower Limb, Varix | Not applicable | Active not recruiting | Ryazan State Medical University | 100 | 2023-04-01 | 2025-07-23 |
| Quercetin for Cardio-Skeletal Muscle Health and Estrogen Deficiency Placebo oral soft chew, Quercetin - Menopause Related Conditions | Phase 4 | Withdrawn | Wake Forest University Health Sciences | 2022-09-01 | 2022-10-10 | |
| Therapeutic Efficacy of Quercetin Versus Its Encapsulated Nanoparticle on Tongue Squamous Cell Carcinoma Cell Line Quercetin 3,3',4',5,6-Pentahydroxyflavone, 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one, Quercetin-encapsulated PLGA-PEG nanoparticles (Nano-QUT), Doxorubicin chemotherapeutic drug as a positive control - Oral Cancer | Phase 2 | Unknown | Cairo University | 1000000 | 2022-07-01 | 2022-07-13 |
| An Open-Label Intervention Trial to Reduce Senescence and Improve Frailty in Adult Survivors of Childhood Cancer Dasatinib plus Quercetin, Fisetin - Frailty, Childhood Cancer | Phase 2 | Active not recruiting | St. Jude Children's Research Hospital | 120 | 2022-06-06 | 2026-09-30 |
| Influence of Flavonoids and Caffeine Supplementation on Resting Metabolism Flavonoid, caffeine, Placebo - Diet Modification | Not applicable | Completed | Appalachian State University | 25 | 2018-04-22 | 2019-07-05 |
| Effects of COcoa Supplement in FRail Elderly Subjects (COFRE) Placebo, Flavonoids, No Flavonoids - Sarcopenia, Frail Elderly Syndrome | Not applicable | Completed | National Polytechnic Institute, Mexico | 30 | 2017-01-01 | 2018-07-13 |
| Calcium Dobesilate vs Flavonoids for the Treatment of Early Hemorrhoidal Disease Flavonoids, CDobi - Hemorrhoids | Phase 4 | Completed | Services Hospital, Lahore | 100 | 2016-12-01 | 2018-12-26 |
| Effect of a Proprietary Dietary Supplement on Fecal Volatile Organic Compounds Placebo, Flavonoids, Flavonoids+Prebiotics - Healthy | Not applicable | Completed | Pharmanex | 27 | 2016-08-01 | 2017-02-23 |
| Safety and Efficacy of a Flavonoids- and omega3s-based Compound for the Treatment of Muscular Dystrophies Flavonoids, DHA, EPA, placebo compound - Muscular Dystrophies, Muscle Inflammation | Not applicable | Completed | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | 29 | 2016-02-28 | 2017-10-25 |
| Inhibition of HBV Replication and Biological Reversal of Cirrhosis (F3-F4) and HCC by Flavonoids Flavonoid, Tenofovir - Hepatitis B Virus Infection | Phase 4 | Completed | Trieu, Nguyen Thi, M.D. | 134 | 2015-11-30 | 2026-06-05 |
| Flavonoid-rich Supplement Influence on the Human Metabolome Flavonoid, Placebo - Inflammation | Not applicable | Completed | Appalachian State University | 110 | 2015-08-01 | 2017-02-02 |
| Dietary Bioflavonoid Supplementation for the Prevention of Neoplasia Recurrence Flavonoids - Colorectal Cancer | Phase 2 | Suspended | Technische Universität Dresden | 382 | 2015-05-01 | 2012-02-03 |
| Effects of Soluble Phosphate in Humans P1000/Ca0, P1000/Ca500, P1000/Ca1000 - Healthy Volunteers | Not applicable | Completed | University of Jena | 62 | 2014-04-01 | 2015-12-02 |
| An Acute Human Intervention With Flavonoid to Investigate Absorption, Metabolism and Excretion Flavonoids - Pharmacokinetics of Flavonoids in Humans | Not applicable | Unknown | University of East Anglia | 240 | 2013-07-01 | 2013-08-14 |
| Physiological Effects of Grape Seed Extract in Diastolic Heart Failure grape seed extract (MegaNatural BP, Polyphenolics, Inc.) - Diastolic Heart Failure, Hypertensive Heart Disease | Phase 1 | Completed | University of Michigan | 15 | 2010-10-01 | 2017-06-06 |
| The Effects of Plant Bioactives on Platelet Function Ex-vivo treatments with flavonoids - Healthy | Not applicable | Completed | Quadram Institute Bioscience | 15 | 2010-06-01 | 2013-03-06 |
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Hemorrhoids (2) · Colorectal Neoplasms (1) · Diabetes Mellitus (1) · Diabetic Nephropathies (1) · Fatigue Syndrome, Chronic (1) · Frailty (1) · Heart Failure (1) · Heart Failure, Diastolic (1) · Hemorrhage (1) · Hepatitis B (1) · Hypertension (1) · Inflammation (1) · Mouth Neoplasms (1) · Muscular Dystrophies (1) · Myositis, Inclusion Body (1)
Appalachian State University (2) · Cairo University (1) · Chiang Mai University (1) · Democritus University of Thrace (1) · Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico (1) · Fytexia (1) · Guillermo Ceballos Reyes (1) · National Polytechnic Institute, Mexico (1) · Pharmanex (1) · Quadram Institute Bioscience (1) · Ryazan State Medical University (1) · Services Hospital, Lahore (1) · St. Jude Children's Research Hospital (1) · Technische Universität Dresden (1) · Texas Tech University Health Sciences Center (1)
United States (7) · United Kingdom (3) · Germany (2) · Egypt (1) · Greece (1) · Italy (1) · Mexico (1) · Pakistan (1) · Russia (1) · Spain (1) · Thailand (1) · Vietnam (1)
David C Nieman, DrPH (2) · Anne-Marie Minihane, PhD (1) · Dr. Waris Farooka, MBBS, FCPS, FRCS, FACS (1) · Gregory T. Armstrong, MD, MSCE (1) · Harald Hoensch, Professor (1) · Igor Suchkov (1) · Jeremy PE Spencer, PhD (1) · Laurie T Butler, PhD (1) · Leanne Groban, MD (1) · Michael Glei, Prof. Dr. (1) · Michael Lefevre, PhD (1) · Nguyen Thi Trieu, MD (1) · Paul Kroon, phD (1) · Scott L Hummel, MD, MS (1) · Tetyana Vasylyeva, MD, PhD (1)
PMID 26786148, PMID 29452584, PMID 31056655, PMID 31396142, PMID 40368267
U01CA246510 (1)