68 completed, 8 unknown, 7 recruiting, 6 not yet recruiting. 36 Not applicable, 20 Phase 2, 14 Phase 3, 13 Phase 4, 8 Phase 1.
Follow Diabetic Neuropathy: new trials by email Literature Review of Diabetic Neuropathy trials Research Report on Diabetic Neuropathy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| DLBS1033 as Adjunctive Therapy for Patients With Diabetic Neuropathy DLBS1033, Placebo - Diabetic Neuropathy | Not applicable | Not yet recruiting | RS H Adam Malik | 80 | 2026-08-01 | 2026-07-06 |
| Extended-release Pregabalin for the Treatment of Neuropathic Pain in Patients With Diabetic Peripheral Neuropathy and Postherpetic Neuralgia Experimental: Pregabalin XR, Comparator: Dorene Tabs, Comparator placebo - Diabetic Neuropathy, Neuropathic Pain | Phase 3 | Recruiting | Brainfarma Industria Química e Farmacêutica S/A | 348 | 2026-06-18 | 2026-07-20 |
| tSCS and AR Training on QoL and Physical Activity in Diabetic Neuropathy Patients Transcutaneous spinal cord stimulation Group, Augmented reality - Diabetic Neuropathy | Not applicable | Not yet recruiting | Riphah International University | 36 | 2026-06-15 | 2026-06-02 |
| Comparative Effects of Perturbation-Based Balance Training on Firm Surface and Rolling Board for Diabetic Neuropathy Patients Group A (Perturbation Based Training on Firm Surface), Group B (Perturbation Based Training on Rolling Board) - Balance Impairment, Diabetic Neuropathy | Not applicable | Not yet recruiting | University of Faisalabad | 42 | 2026-05-20 | 2026-05-20 |
| Plantar Pressure and Acceptance of the LEEF-shoe in Individuals With Diabetes-related Neuropathy LEEF-shoe, standard orthopaedic shoe - Diabetic Neuropathy | Not applicable | Recruiting | University Medical Center Groningen | 30 | 2026-04-01 | 2026-03-23 |
| Effects of Ankle Block on Postoperative Analgesia in Diabetic and Non-Diabetic Patients Ultrasound-Guided Ankle Block - Diabetes Mellitus, Diabetic Neuropathy | Not applicable | Not yet recruiting | Fatih Sultan Mehmet Training and Research Hospital | 46 | 2026-03-01 | 2026-02-11 |
| Efficacy and Feasibility of BurstDR SCS in Painful Diabetic Neuropathy BurstDR Spinal Cord Stimulation - Painful Diabetic Neuropathy (PDN), Diabetic Neuropathy | Not applicable | Enrolling by invitation | TriCity Research Center | 20 | 2025-12-15 | 2026-05-08 |
| Vitamin D, Nerve Growth Factor and Nerve Conduction Studies in Adult Male Type 2 Diabetic Neuropathy Patients nerve conduction studies, Nerve Growth Factor, 25(OH) vitamin D - Diabetic Neuropathy | Not yet recruiting | Aswan University | 57 | 2025-12-01 | 2025-11-19 | |
| Effects of Turning Based Dual Task Training on Balance and Mild Cognitive Impairment in Diabetic Peripheral Neuropathy Turning Based Dual Task Training, Dual-Task Training - Diabetic Neuropathy, Balance | Not applicable | Completed | Foundation University Islamabad | 50 | 2025-11-20 | 2026-05-14 |
| Effect of Golden Rice-Piper Crocatum Cookies on Neuropathy Prevention in Diabetes Golden Rice Cookies With Piper Crocatum, Golden Rice Cookies Without Piper Crocatum - Diabetic Neuropathy, Diabetes Mellitus (DM) | Not applicable | Completed | Hasanuddin University | 102 | 2025-10-20 | 2026-10-01 |
| GlucoBites Cookies (Gynura Procumbens) for Glycemic Control and Prevention of Diabetic Foot Ulcer Risk in Type 2 Diabetes GlucoBites (with Gynura procumbens), Control Cookies (without Gynura procumbens) - Type 2 Diabetes Mellitus, Diabetic Neuropathy | Not applicable | Not yet recruiting | Andina Setyawati | 126 | 2025-09-20 | 2025-09-03 |
| Additional Effects of Sensory Integration Along With Focused Regimen Exercises on Kinaesthesia & Proprioception in Diabetic Peripheral Neuropathy. Sensory integration and focused regimen, Focused Regimen Exercise - Diabetic Neuropathy, Proprioception | Not applicable | Completed | Foundation University Islamabad | 30 | 2025-09-15 | 2026-01-15 |
| CGM-Guided Acarbose for Painful Diabetic Neuropathy Acarbose 50 mg, Placebo - Diabetes, Diabetes Complications | Phase 1 | Completed | Shifa International Hospital | 170 | 2025-09-01 | 2026-03-03 |
| Effect of Melatonin in Patients With Diabetic Peripheral Neuropathy Melatonin - Diabetic Peripheral Neuropathy, Diabetic Neuropathy | Phase 2 | Recruiting | Ain Shams University | 60 | 2025-07-04 | 2026-07-21 |
| Comparison of Active vs Passive Neural Mobilizations Effects in Improving Burning Pain, Muscular Strength, and Range of Motion in Patients With Diabetic Neuropathy Active Neural Mobilzations, Passive Neural Mobilzations - Neuropathy, Diabete Mellitus | Not applicable | Enrolling by invitation | Dow University of Health Sciences | 60 | 2025-06-04 | 2025-09-03 |
| The Relation Between Diabetic Neuropathy and Muscle Mass in Type 2 Diabetes Mellitus Patients Diabetic Neuropathy, Sarcopenia | Recruiting | Ain Shams University | 60 | 2025-05-30 | 2025-05-06 | |
| Comparative Analysis Between Textured Insoles and Roods Technique Affecting Balance in DNP. Roods Facilitatory Technique, Textured Insoles - Diabetic Neuropathy, Diabetes | Not applicable | Completed | University of Faisalabad | 44 | 2025-03-04 | 2026-07-17 |
| Effect of Reiki on Neuropathic Pain Severity and Sleep Quality in Patients With Diabetic Neuropathy Reiki Group, Sham Reiki Group - Diabetic Neuropathy | Not applicable | Recruiting | TC Erciyes University | 60 | 2024-11-01 | 2025-02-14 |
| Additional Effects of Neural Mobilization on Pain, Balance and Quality of Life in Diabetic Neuropathy Neural mobilization with Balance training with conventional physical Therapy, Balance Training only with conventional physical therapy - Diabetic Neuropathy, Postural Balance | Not applicable | Recruiting | Foundation University Islamabad | 32 | 2024-09-13 | 2025-10-07 |
| Clinical Outcomes Related to Treatment of Distal Symmetric Polyneuropathy Using Semiconductor Embedded Therapeutic Socks Semiconductor Embedded Therapeutic Socks, Placebo Socks - Diabetic Neuropathy | Not applicable | Recruiting | Endocrine Research Solutions | 80 | 2024-06-11 | 2025-02-25 |
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Diabetic Neuropathies (99) · Diabetes Mellitus (25) · Pain (15) · Neuralgia (10) · Peripheral Nervous System Diseases (7) · Diabetes Mellitus, Type 2 (5) · Diabetic Foot (4) · Neuralgia, Postherpetic (4) · Chronic Pain (3) · Diabetes Complications (3) · Peripheral Arterial Disease (3) · Carpal Tunnel Syndrome (2) · Cognitive Dysfunction (2) · Diabetic Retinopathy (2) · Foot Ulcer (2)
Endocrine System Diseases (99) · Nervous System Diseases (99) · Neuromuscular Diseases (99) · Diabetes Complications (96) · Peripheral Nervous System Diseases (92) · Diabetes Mellitus (74) · Metabolic Diseases (32) · Nutritional and Metabolic Diseases (32) · Glucose Metabolism Disorders (31) · Pathological Conditions, Signs and Symptoms (30) · Neurologic Manifestations (29) · Signs and Symptoms (29) · Pain (13) · Cardiovascular Diseases (9) · Vascular Diseases (7)
2-(acetylamino)-3-methoxy-N-(phenylmethyl)-, (2R)- (3) · Exercise (3) · Diet, Vegan (2) · Gabapentin (2) · Lidocaine (2) · Lidoderm (2) · Pregabalin (2) · Thioctic Acid (2) · 4-bromobenzoyl-(alpha-aminoisobutyric acid)(5)-leucyl-(alpha-aminoisobutyric acid)(2)-methoxy (1) · AZD2066 (1) · Acarbose (1) · Acupuncture Therapy (1) · Capsaicin (1) · Centella asiatica extract (1) · Cholecalciferol (1)
Foundation University Islamabad (3) · UCB Pharma (3) · Ain Shams University (2) · BioDelivery Sciences International (2) · Endo USA Inc., a Keenova Therapeutics Company (2) · Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (2) · Physicians Committee for Responsible Medicine (2) · Riphah International University (2) · University Medical Center Groningen (2) · University of Faisalabad (2) · Andina Setyawati (1) · Aristotle University Of Thessaloniki (1) · AstraZeneca (1) · Aswan University (1) · Avanir Pharmaceuticals (1)
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PMID 35587172, PMID 15891953, PMID 17392551, PMID 17977931, PMID 18095233, PMID 18619874, PMID 19366965, PMID 19386127, PMID 19454870, PMID 20067958, PMID 21162697, PMID 21185118, PMID 21346609, PMID 21775755, PMID 22314263, PMID 22365309, PMID 22704856, PMID 22717465, PMID 23340531, PMID 24898524, PMID 25095826, PMID 25278335, PMID 25348629, PMID 25410210, PMID 25575710, PMID 26269202, PMID 26345602, PMID 27417167, PMID 29379943, PMID 30804739, PMID 32844212, PMID 33070667, PMID 33637134, PMID 34867030, PMID 35922961, PMID 36148823, PMID 38376038, PMID 40890741
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