9 completed, 4 unknown. 4 Not applicable, 3 Phase 4, 2 Early Phase 1, 2 Phase 2, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 4 | Completed 4 |
| Phase 4 | 3 | Unknown 2, Completed 1 |
| Early Phase 1 | 2 | Completed 1, Unknown 1 |
| Phase 2 | 2 | Completed 1, Unknown 1 |
| Phase 3 | 2 | Completed 1, Unknown 1 |
| Phase 1 | 1 | Completed 1 |
Follow this drug Literature Review of Centella asiatica extract trials Research Report on Centella asiatica extract
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Scalp Care Efficacy Evaluation for Premium Revitalizing Elixir Placebo control, Base formula only, Base formula plus IGF-1 and FGF-7 - Scalp Health, Hair Condition | Not applicable | Completed | Hungkuang University | 60 | 2025-11-01 | 2026-07-10 |
| Centella Asiatica in Older Adults Centella Asiatica, Placebo Comparator - Endothelial Dysfunction | Not applicable | Completed | National University of Natural Medicine | 23 | 2025-02-01 | 2026-07-01 |
| Effectiveness of Asiaticoside as Intracanal Medication on Infectious/Inflammatory Contents in Teeth With Apical Periodontitis Calcium Hydroxide Intracanal medication, Leddermix Intracanal medication, Asiaticoside Intracanal medication - Intracanal Medication | Phase 2 / Phase 3 | Unknown | Mansoura University | 36 | 2023-11-20 | 2024-08-22 |
| Topical Agents Containing Magnesium Sulfate & Wound Healing in the Rat Model placebo comparator, sham comparator, Experimental drug 1 - Wound Heal | Early Phase 1 | Unknown | Başakşehir Çam & Sakura City Hospital | 30 | 2021-03-22 | 2021-05-14 |
| Effects of Bromelain and Boswellia Serrata Casperome With Centella Asiatica and Vitamins on Edema, Paresthesia and Postoperative Pain After Quadrantectomy With or Without Sentinel Lymph Node Biopsy. Bromelain/Boswellia Serrata Casperome, Centella Asiatica/Vitamins, Placebo - Breast Cancer Female, Pain, Postoperative | Phase 4 | Unknown | University of Bari Aldo Moro | 120 | 2020-12-31 | 2020-12-16 |
| Effect of Centella Asiatica on Xerotic Skin in Diabetes Mellitus Type 2 Centella Asiatica Extract, Topical CA, Petroleum jelly - Xerosis Cutis, Diabetes Mellitus, Type 2 | Phase 4 | Unknown | Universitas Indonesia | 159 | 2018-07-30 | 2019-01-24 |
| Pain and Bleeding in Subjects With Acute Anal Fissure: Comparative Evaluation of Three Treatments Centella, Proctocella, Flavonil® cps - Acute Anal Fissure | Phase 4 | Completed | University of Roma La Sapienza | 99 | 2018-05-01 | 2018-07-13 |
| Effects of Herbal Products on Reduction of Radiation-induced Dermatitis in Breast Cancer Patients Control, Cucumber cream, Centella cream - Radiodermatitis, Breast Neoplasms | Not applicable | Completed | Chulabhorn Cancer Center | 150 | 2016-05-01 | 2018-06-25 |
| Centella Asiatica (Gotukola) Mouthwash as an Adjunct to Mechanical Plaque Control Gotukola, Scaling - Gingival Diseases | Phase 1 | Completed | Sri Hasanamba Dental College and Hospital | 36 | 2015-08-01 | 2016-07-11 |
| The Effect of Centella Asiatica Cream on Scar Tenderness Who Underwent Open Carpal Tunnel Release Surgery undefinedCentella Asiatica Extract - To Prevent Scar Formation for Patients Underwent Surgery | Early Phase 1 | Completed | Mustafa Balevi,MD | 280 | 2011-01-01 | 2021-08-23 |
| Effect of Bacopa Monniera Extract on Cognition and Anxiety and Exploration of PK Properties Brahmi, Placebo - Cognition, Anxiety | Not applicable | Completed | Unilever R&D | 84 | 2010-03-01 | 2015-06-04 |
| The Effect of New Dentifrices Containing Centella Asiatica and Bamboo Salt on Reducing Plaque and Gingivitis Centella asiatica and bamboo salt, Centella asiatica - Labor Trial Refused | Phase 3 | Completed | LG Household & Health Care Ltd. | 33 | 2009-03-01 | 2015-11-30 |
| Centella Asiatica Selected Triterpenes (CAST) for Diabetic Neuropathy Centella asiatica selected triterpenes (CAST), Placebo - Diabetic Neuropathy | Phase 2 | Completed | Oregon Health and Science University | 43 | 2007-09-01 | 2012-11-12 |
Breast Neoplasms (2) · Alopecia (1) · Anxiety Disorders (1) · Carpal Tunnel Syndrome (1) · Dental Pulp Necrosis (1) · Diabetes Mellitus (1) · Diabetes Mellitus, Type 2 (1) · Diabetic Neuropathies (1) · Fissure in Ano (1) · Gingival Diseases (1) · Hemorrhage (1) · Inflammation (1) · Pain (1) · Pain, Postoperative (1) · Radiation Injuries (1)
Başakşehir Çam & Sakura City Hospital (1) · Chulabhorn Cancer Center (1) · Hungkuang University (1) · LG Household & Health Care Ltd. (1) · Mansoura University (1) · Mustafa Balevi,MD (1) · National University of Natural Medicine (1) · Oregon Health and Science University (1) · Sri Hasanamba Dental College and Hospital (1) · Unilever R&D (1) · Universitas Indonesia (1) · University of Bari Aldo Moro (1) · University of Roma La Sapienza (1)
India (2) · Italy (2) · Turkey (Türkiye) (2) · United States (2) · Egypt (1) · Indonesia (1) · Taiwan (1) · Thailand (1)
Ali Balevi (1) · Amany Bader, prof (1) · Hyun-Duck Kim, DDS, PhD (1) · Jau-Shin Lou, MD, PhD (1) · Krishnamachari Srinivasan (1) · Saengrawee Thanthong, M.N.S. (1) · Suhendro Suhendro, Doctor (1) · Talat Mohammadi, PG student (1) · Youssry Elhawary, prof (1)
PMID 10443466, PMID 14566480, PMID 16893745, PMID 20118623, PMID 21153830, PMID 21694984, PMID 23825733, PMID 25525844, PMID 29844250, PMID 39929877
R21AT003668 (1)