4 completed, 2 not yet recruiting, 2 unknown. 8 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 8 | Completed 4, Not yet recruiting 2, Unknown 2 |
Follow Depressive Symptoms: new trials by email Literature Review of Depressive Symptoms trials Research Report on Depressive Symptoms
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Dexmedetomidine-Esketamine Combination on Depression and Anxiety After Laparoscopic Ureteral Reconstruction Combined dexmedetomidine-esketamine administration, Placebo administration - Ureteral Stricture, Dexmedetomidine | Phase 4 | Not yet recruiting | Peking University First Hospital | 658 | 2026-08-01 | 2026-08-14 |
| Intranasal Esketamine-dexmedetomidine Combination and Postpartum Depression Esketamine-dexmedetomidine combination, Placebo - Parturients, Depressive Symptoms | Phase 4 | Not yet recruiting | Peking University First Hospital | 164 | 2026-06-01 | 2026-06-15 |
| Oral Aspirin + Ketamine as Adjunct to Oral Antidepressant Therapy for Depression VTS-K - Treatment Resistant Depression, Major Depressive Disorder | Phase 4 | Completed | Theresa Jacob, PhD, MPH | 15 | 2022-12-06 | 2026-04-21 |
| Acute and Long-Term Antidepressant Treatment Success in Adolescents With Anxiety (AtLAS-A) Duloxetine, Escitalopram - Anxiety, Depressive Symptoms | Phase 4 | Unknown | University of Cincinnati | 60 | 2020-01-01 | 2024-08-29 |
| Dexamethasone and Ketamine on Change of Postoperative Mood Ketamine Hydrochloride, dexamethasone, and combination of two drugs - Depressive Symptoms | Phase 4 | Completed | Wonkwang University Hospital | 93 | 2017-05-02 | 2017-06-21 |
| Effect of Subanesthetic Dose of Ketamine Combined With Propofol on Cognitive Function in Depressive Patients Undergoing Electroconvulsive Therapy ketamine and propofol, propofol and normal saline - Depressive Symptoms, Impaired Cognition | Phase 4 | Unknown | First Affiliated Hospital of Chongqing Medical University | 132 | 2015-01-01 | 2014-12-02 |
| Rasagiline in Cognitive-impairment Related Depression: AzileCt in COgnitive-impairment Related DepressiOn Rasagiline, Placebo - Depressive Symptoms, Parkinson's Disease | Phase 4 | Completed | Lundbeck Italia S.p.A. | 121 | 2010-03-01 | 2021-08-31 |
| Combination Therapy in Patients With Depression Atomoxetine Hydrochloride, Sertraline, Placebo - Depressive Symptoms | Phase 4 | Completed | Eli Lilly and Company | 214 | 2003-06-01 | 2007-06-13 |
Depression (8) · Anxiety Disorders (2) · Agnosia (1) · Cognition Disorders (1) · Depression, Postpartum (1) · Depressive Disorder, Major (1) · Depressive Disorder, Treatment-Resistant (1) · Parkinson Disease (1)
Behavior (8) · Behavioral Symptoms (8) · Mental Disorders (5) · Depressive Disorder (2) · Mood Disorders (2) · Nervous System Diseases (2) · Basal Ganglia Diseases (1) · Brain Diseases (1) · Central Nervous System Diseases (1) · Female Urogenital Diseases and Pregnancy Complications (1) · Movement Disorders (1) · Neurobehavioral Manifestations (1) · Neurocognitive Disorders (1) · Neurodegenerative Diseases (1) · Neurologic Manifestations (1)
Ketamine (3) · Saline Solution (2) · Aspirin (1) · Atomoxetine Hydrochloride (1) · Dexamethasone (1) · Duloxetine Hydrochloride (1) · Escitalopram (1) · Propofol (1) · Sertraline (1) · rasagiline (1)
Peking University First Hospital (2) · Eli Lilly and Company (1) · First Affiliated Hospital of Chongqing Medical University (1) · Lundbeck Italia S.p.A. (1) · Theresa Jacob, PhD, MPH (1) · University of Cincinnati (1) · Wonkwang University Hospital (1)
China (3) · United States (3) · Italy (1) · South Korea (1)
Cheol Lee, M.D.,Ph.D (1) · Dong-Xin Wang (1) · Dong-Xin Wang, MD, PhD (1) · Jeffrey R Strawn, MD (1) · Su Min (1) · Theresa Jacob, PhD, MPH (1)
2009 (1)