8 recruiting, 4 completed, 2 active not recruiting, 2 not yet recruiting. 14 Not applicable, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 14 | Recruiting 6, Completed 4, Active not recruiting 2, Not yet recruiting 2 |
| Phase 1 | 1 | Recruiting 1 |
| Phase 3 | 1 | Recruiting 1 |
Follow Depression in Adults: new trials by email Literature Review of Depression in Adults trials Research Report on Depression in Adults
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| INNOV5-MH-MAROC: Integrated Mental Health Care for Adolescents and Adults in Primary Care Centers and Schools in Morocco INNOV5 Integrated Mental Health Program, Enhanced Treatment as Usual (TAU+) - Depression in Adolescence, Depression in Adults | Not applicable | Not yet recruiting | Swiss Medical Academy Maroc | 146 | 2028-03-01 | 2025-12-02 |
| The Effects of Cognitive Behavioral Therapy on Insulin Resistance in People With HIV Internet cognitive behavioral therapy (iCBT-D), Active Control (AC) - HIV, Depression in Adults | Not applicable | Recruiting | Indiana University | 150 | 2026-04-10 | 2026-08-21 |
| ACT for Individuals With MNCD and Their Care Partners Acceptance Commitment Therapy - Depression in Adults, Anxiety Disorder Generalized | Phase 1 | Recruiting | Texas Tech University | 100 | 2026-04-01 | 2026-05-15 |
| GynMDD Add-On to Supportive Psychotherapy in Mild to Moderate Depression GynMDD, Placebo - Depression, Depression Disorder | Not applicable | Recruiting | Fondation FondaMental | 168 | 2026-03-24 | 2026-10-07 |
| Brief Culturally Adapted Behavioral Activation Therapy for Adults With Depression in Indonesian Primary Care: A Type-2 Hybrid Effectiveness-Implementation Trial Training and supervision on BAT - Depression in Adults | Not applicable | Completed | Gadjah Mada University | 96 | 2026-02-11 | 2026-10-13 |
| Neuroma-Associated Pain Management After Combat-Related Trauma in Ukraine cryoablation, Radiofrequency ablation alone - Pain Management, Quality of Life | Not applicable | Completed | Ukrainian Society of Regional Anesthesia and Pain Therapy | 100 | 2026-02-05 | 2026-10-19 |
| Positive Affect Treatment for Spanish-Speaking Individuals Positive Affect Treatment - Anhedonia, Depression in Adults | Not applicable | Active not recruiting | Southern Methodist University | 12 | 2026-01-20 | 2026-03-25 |
| Comprehensive Multicenter Study on the Management of Acute Pain Following Thoracic Combat-Related Trauma in Ukraine Cryoablation, Radiofrequency ablation alone - Pain Management, Thoracic Trauma | Not applicable | Recruiting | Lviv National Medical University | 50 | 2026-01-01 | 2026-02-02 |
| A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder CYB003, Psychological Support - Major Depressive Disorder (MDD), Depression in Adults | Phase 3 | Recruiting | Cybin IRL Limited | 330 | 2025-12-10 | 2026-10-16 |
| Structured Group Therapy in Reducing Depression and Anxiety in Pakistan Structured group therapy - Depression in Adults, Anxiety | Not applicable | Not yet recruiting | Pakistan Association of Cognitive Therapists | 108 | 2025-11-01 | 2025-11-20 |
| Pilot Study of Brief Culturally Adapted Behavioral Activation for Adults With Depression in Primary Care Setting brief culturally adapted behavioral activation - Depression in Adults | Not applicable | Completed | Gadjah Mada University | 12 | 2025-09-22 | 2026-07-21 |
| Comparing the Efficacy of Heated Yoga and Sauna as a Treatment for Depression heated yoga, sauna, mindfulness app - Depression Disorders, Depression - Major Depressive Disorder | Not applicable | Recruiting | Massachusetts General Hospital | 120 | 2025-09-12 | 2026-07-06 |
| Telehealth Collaborative Care Model (CoCM) in Lung Cancer High Touch Outreach - Lung Cancer (Diagnosis), Anxiety | Not applicable | Recruiting | Abramson Cancer Center at Penn Medicine | 30 | 2025-08-18 | 2026-05-28 |
| Multimodal Intervention for Older Adults After an Earthquake Multimodal intervention - Frailty at Older Adults, Post-Traumatic Stress Disorder in Old Age | Not applicable | Completed | Kahramanmaras Sutcu Imam University | 60 | 2024-09-15 | 2025-12-09 |
| An ISO Principle-Based Music Intervention for Reducing Stress, Anxiety, and Depression ISO Principle Music Intervention, DUL Principle Music Intervention, ISO Principle Music Intervention with Waiting-list - Stress, Anxiety | Not applicable | Recruiting | Shanghai Mental Health Center | 2000 | 2024-04-23 | 2026-07-23 |
| Neuro-affective Response to Light in Depressed Adolescents and Young Adults Blue Light, Red Light - Depression in Adolescence, Depression in Adults | Not applicable | Active not recruiting | University of Pittsburgh | 80 | 2023-06-14 | 2026-09-02 |
| A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease There is no intervention in this study - Gut Microbiome, Gastrointestinal Microbiome | Suspended | ProgenaBiome | 1000 | 2019-07-11 | 2026-09-21 |
Depression (9) · Anxiety Disorders (6) · Agnosia (2) · Depressive Disorder, Major (2) · Diabetes Mellitus (2) · Generalized Anxiety Disorder (2) · Hypesthesia (2) · Neuralgia (2) · Acne Vulgaris (1) · Acquired Immunodeficiency Syndrome (1) · Alzheimer Disease (1) · Amyotrophic Lateral Sclerosis (1) · Anhedonia (1) · Arthritis, Rheumatoid (1) · Autism Spectrum Disorder (1)
Behavior (11) · Behavioral Symptoms (9) · Mental Disorders (8) · Pathological Conditions, Signs and Symptoms (6) · Nervous System Diseases (4) · Signs and Symptoms (4) · Mood Disorders (3) · Neurobehavioral Manifestations (3) · Neurologic Manifestations (3) · Neuromuscular Diseases (3) · Pathologic Processes (3) · Depressive Disorder (2) · Endocrine System Diseases (2) · Glucose Metabolism Disorders (2) · Immune System Diseases (2)
Cryosurgery (2) · Radiofrequency Ablation (2) · Acceptance and Commitment Therapy (1) · Blue Light (1) · Red Light (1) · Steam Bath (1) · Waiting Lists (1)
Gadjah Mada University (2) · Abramson Cancer Center at Penn Medicine (1) · Cybin IRL Limited (1) · Fondation FondaMental (1) · Indiana University (1) · Kahramanmaras Sutcu Imam University (1) · Lviv National Medical University (1) · Massachusetts General Hospital (1) · Pakistan Association of Cognitive Therapists (1) · ProgenaBiome (1) · Shanghai Mental Health Center (1) · Southern Methodist University (1) · Swiss Medical Academy Maroc (1) · Texas Tech University (1) · Ukrainian Society of Regional Anesthesia and Pain Therapy (1)
United States (8) · Indonesia (2) · Ukraine (2) · Australia (1) · China (1) · Czechia (1) · France (1) · Germany (1) · Greece (1) · Ireland (1) · Pakistan (1) · Poland (1) · Switzerland (1) · Turkey (Türkiye) (1) · United Kingdom (1)
Adriane M Soehner, PhD (1) · Alexandria Muench, PsyD (1) · Alicia E Meuret, Ph.D. (1) · Felix Mazer (1) · Maren B Nyer, PhD (1) · Sabine Hazan, MD (1) · Samir K Gupta, MD (1)
P50CA271338 (1), R01DK141366 (1), R21MH127294 (1)