14 completed, 3 recruiting, 2 terminated, 1 active not recruiting. 18 Not applicable, 2 Phase 2, 2 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 18 | Completed 11, Recruiting 2, Terminated 2, Active not recruiting 1, Unknown 1, Withdrawn 1 |
| Phase 2 | 2 | Completed 1, Recruiting 1 |
| Phase 4 | 2 | Completed 2 |
Follow Blue Light: new trials by email Literature Review of Blue Light trials Research Report on Blue Light
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluating Photodynamic Therapy Used to Treat Cutaneous Squamous Cell Carcinoma in Situ (isSCC) on the Face, Upper Extremities & Trunk. Aminolevulinic Acid 20% Topical Solution with Blue Light (dose 20 J/cm2), Aminolevulinic Acid 20% Topical Solution with Blue Light (dose 10 J/cm2) - Cutaneous Squamous Cell Carcinoma in Situ, Facial Cutaneous Squamous Cell Carcinoma in Situ | Phase 2 | Recruiting | The Center for Clinical and Cosmetic Research | 30 | 2025-11-25 | 2026-11-12 |
| Temperature Rise Caused by Short or Long-wavelengths Red Light, Blue Light - Post-operative Pain | Not applicable | Recruiting | University of Florida | 50 | 2025-09-22 | 2025-11-19 |
| WatchWell: Simple and Practical Strategies to Reduce the Negative Health Impact of Sedentary Screen Time Blue light, Eating, Standing - Sedentary Time, Cardiovascular Diseases | Not applicable | Completed | Arizona State University | 5 | 2025-08-07 | 2026-10-01 |
| The Role of Circadian Clock Proteins in Innate and Adaptive Immunity Blue Light - Pneumonia, Necrotizing Soft Tissue Infection | Not applicable | Recruiting | Washington University School of Medicine | 144 | 2024-10-29 | 2026-02-11 |
| Effects of Combined Blue and Red Home-Based Light Therapy on Sleep in Adults With Self-Reported Sleep Difficulties LED portable light therapy bulb - Sleep | Not applicable | Completed | Colorado State University | 20 | 2024-07-09 | 2026-03-12 |
| Evaluating the Use of Photodynamic Therapy to Treat Facial Cutaneous Squamous Cell Carcinoma in Situ (isSCC) Aminolevulinic Acid 20% Topical Solution with Blue Light - Facial Cutaneous Squamous Cell Carcinoma in Situ | Phase 2 | Completed | The Center for Clinical and Cosmetic Research | 32 | 2023-08-08 | 2025-02-12 |
| Neuro-affective Response to Light in Depressed Adolescents and Young Adults Blue Light, Red Light - Depression in Adolescence, Depression in Adults | Not applicable | Active not recruiting | University of Pittsburgh | 80 | 2023-06-14 | 2026-09-02 |
| Blue and Amber Light Exposure in Patients With Rectal and Pancreatic Cancer Blue light, Amber light, Ambient White Light - Pancreatic Neoplasms, Rectal Neoplasms | Not applicable | Terminated | Matthew Neal MD | 2 | 2022-08-14 | 2024-05-21 |
| Efficacy of Blue Light Treatment in Patients With Nonseasonal Major Depressive Disorder blue light, bright light, dim light - Depression | Not applicable | Unknown | Shanghai Zhongshan Hospital | 162 | 2020-10-01 | 2020-09-18 |
| Light Therapy in Cardiopulmonary Bypass Surgery Blue light - Acute Kidney Injury, Inflammation | Not applicable | Withdrawn | University of Pittsburgh | 2020-09-01 | 2022-01-20 | |
| Opioid Sparing Potential of Light-Induced Analgesia Green light, Clear light, Blue Light - Pain | Not applicable | Completed | Duke University | 94 | 2019-06-17 | 2021-10-13 |
| Blue Light Therapy for Liver Surgery Blue light - Acute Kidney Injury, Liver Injury | Not applicable | Terminated | University of Pittsburgh | 6 | 2017-01-01 | 2019-04-05 |
| Acute Effects of Whole Body Blue Light Exposure on Blood Pressure Blue light, control exposure - Blue Light | Not applicable | Completed | Heinrich-Heine University, Duesseldorf | 20 | 2016-08-01 | 2017-11-09 |
| Blue vs Red Light During Levulan Based Photodynamic Therapy in Patients With Basal Cell Nevus Syndrome Levulan, Red Light PDT, Blue Light PDT - Basal Cell Nevus Syndrome | Not applicable | Completed | Edward Maytin, MD, PhD | 3 | 2016-02-01 | 2020-07-30 |
| Bilateral Comparison of Treatment of Facial Actinic Keratoses Using Microneedling and Photodynamic Therapy With Aminolevulinic Acid and Blue Light Versus Photodynamic Therapy With Aminolevulinic Acid and Blue Light Using Two Incubation Times Aminolevulinic Acid (ALA), Environ Cosmetic Roller, BLU-U IIlluminator - Actinic Keratoses | Phase 4 | Completed | Dermatology, Laser & Vein Specialists of the Carolinas | 10 | 2015-10-01 | 2017-07-19 |
| Photodynamic Therapy (PDT) With Levulan and Blue Light for the Treatment of Actinic Cheilitis aminolevulinic acid hydrochloride, Photodynamic therapy with blue light - Actinic Cheilitis | Phase 4 | Completed | Dartmouth-Hitchcock Medical Center | 24 | 2015-04-01 | 2018-10-23 |
| The Use of Microneedles to Expedite Treatment Time in Photodynamic Therapy Microneedle Roller, Aminolevulinic Acid, Blue Light - Keratosis, Actinic | Not applicable | Completed | University of California, Davis | 32 | 2014-11-06 | 2018-11-29 |
| Energy-efficient and Health Promoting Light for Elderly People blue light - Sleep | Not applicable | Completed | Glostrup University Hospital, Copenhagen | 29 | 2013-10-01 | 2018-08-06 |
| Individually Tailored Lighting System to Improve Sleep in Older Adults Blue light, Red light - Sleep Disturbances | Not applicable | Completed | Rensselaer Polytechnic Institute | 46 | 2013-03-01 | 2019-01-29 |
| The Use of Microneedles in Photodynamic Therapy Microneedle, Aminolevulinic Acid, Blue light - Actinic Keratosis | Not applicable | Completed | University of California, Davis | 51 | 2012-07-01 | 2017-06-15 |
Showing 20 of 22. Sign in to see all of them.
Keratosis, Actinic (3) · Acute Kidney Injury (2) · Carcinoma, Squamous Cell (2) · Inflammation (2) · Skin Neoplasms (2) · Squamous Intraepithelial Lesions (2) · Actinic cheilitis (1) · Acute Pain (1) · Basal Cell Nevus Syndrome (1) · Cardiovascular Diseases (1) · Chronic Pain (1) · Depression (1) · Hyperbilirubinemia (1) · Hyperbilirubinemia, Neonatal (1) · Intraabdominal Infections (1)
University of Pittsburgh (3) · The Center for Clinical and Cosmetic Research (2) · University of California, Davis (2) · Arizona State University (1) · Colorado State University (1) · Dartmouth-Hitchcock Medical Center (1) · Dermatology, Laser & Vein Specialists of the Carolinas (1) · Duke University (1) · Edward Maytin, MD, PhD (1) · Glostrup University Hospital, Copenhagen (1) · Heinrich-Heine University, Duesseldorf (1) · Matthew Neal MD (1) · Philips Respironics (1) · Rensselaer Polytechnic Institute (1) · Shanghai Zhongshan Hospital (1)
United States (18) · Denmark (1) · Germany (1)
Mark S Nestor, MD, PhD (2) · Matthew R Rosengart, MD MPH (2) · Adriane M Soehner, PhD (1) · Alfredo Rivera, MD (1) · Carol Glod, PhD (1) · Dorothy Sears, PhD (1) · Edward V. Maytin, MD, PhD (1) · Finn Ebbesen, Professor (1) · Janis Anderson, PhD (1) · Josiane L Broussard, PhD (1) · Line Kessel, MD (1) · Mariana G Figueiro, PhD (1) · Matthew Neal, MD (1) · Michael S Chapman, MD (1)
K23DE034470 (1), R01GM145674 (1), R21MH127294 (1)