42 completed, 28 unknown, 3 recruiting, 2 not yet recruiting. 77 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 77 | Completed 42, Unknown 28, Recruiting 3, Not yet recruiting 2, Active not recruiting 1, Terminated 1 |
Follow Coronary Heart Disease: new trials by email Literature Review of Coronary Heart Disease trials Research Report on Coronary Heart Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Superficial Parasternal Block Combined With Rectus Sheath Block for Open Cardiac Surgery Parasternal and rectus sheath block, ropivacaine 0.25 % - Cardiac Valve Disease, Coronary Heart Disease | Phase 4 | Not yet recruiting | Hôpital du Valais | 100 | 2026-11-01 | 2026-10-22 |
| Effect of Mazdutide on Coronary Plaque in Patients With Coronary Atherosclerosis and Overweight or Obesity Mazdutide, Placebo - Obesity & Overweight, Coronary Heart Disease | Phase 4 | Recruiting | China National Center for Cardiovascular Diseases | 116 | 2026-09-14 | 2026-10-13 |
| Intranasal Dexmedetomidine and Perioperative Myocardial Injury Intranasal Dexmedetomidine, Normal saline - Coronary Heart Disease, Myocardial Injury | Phase 4 | Not yet recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 140 | 2026-08-01 | 2026-07-30 |
| Efficacy and Safety Trials of Yangxinshi Tablets in the Treatment of Patients With Coronary Heart Disease Complicated by Cardiac Dysfunction Yangxinshi tablet, Blank control - Coronary Heart Disease, Cardiac Dysfunction | Phase 4 | Recruiting | SPH Qingdao Growful Pharmacetical Co.,Ltd | 2708 | 2025-11-06 | 2025-11-25 |
| Inclisiran Effectiveness in China: a Pragmatic Randomized Trial inclisiran sodium injection, Standard of Care - Coronary Heart Disease | Phase 4 | Active not recruiting | Novartis Pharmaceuticals | 1590 | 2025-06-17 | 2026-05-29 |
| Effect of Xuesaitong Soft Capsules on Major Risk Factors in Patients With Coronary Heart Disease Xuesaitong Soft Capsule, Placebo - Coronary Heart Disease | Phase 4 | Recruiting | China National Center for Cardiovascular Diseases | 240 | 2024-06-01 | 2025-09-08 |
| Pharmacodynamic and Short-term Effects of Half-dose Ticagrelor With or Without Aspirin vs DAPT From Day of PCI in CCS Aspirin 100 mg + clopidogrel (300 mg load → 75 mg daily) ×6 months, then aspirin monotherapy, Aspirin 100 mg + ticagrelor (90 mg load → 45 mg twice daily) ×6 months, then aspirin monotherapy, Ticagrelor (90 mg load → 45 mg twice daily) monotherapy; aspirin stopped at day 2 after randomisation; continued indefinitely - Coronary Heart Disease | Phase 4 | Completed | Kaohsiung Veterans General Hospital. | 54 | 2024-01-03 | 2026-09-14 |
| Ticagrelor Single Antiplatelet Therapy in Patients With High Risk of Bleeding After DCB for Coronary Small Vessel Disease Ticagrelor, Clopidogrel, Aspirin - Coronary Heart Disease | Phase 4 | Unknown | Fu Wai Hospital, Beijing, China | 292 | 2023-11-15 | 2023-10-18 |
| HuoXin Pills Intervention on Patients With Coronary Heart Disease After Drug-Coated Balloon Implantation Yuekang Huoxin Pills (concentrated pills), Yuekang Huoxin Pills (concentrated pills)simulant - Coronary Heart Disease, Medicine, Chinese Traditional | Phase 4 | Unknown | China National Center for Cardiovascular Diseases | 440 | 2022-08-05 | 2022-08-17 |
| Efficacy and Safety of Shexiang Baoxin Pill in Patients With Ischemia With Non-Obstructive Coronary Artery Shexiang Baoxin pill（MUSKARDIA）, Placebo - Ischemia With Non-Obstructive Coronary Artery, Angina Pectoris | Phase 4 | Completed | Shanghai Hutchison Pharmaceuticals Limited | 240 | 2021-05-11 | 2024-04-23 |
| Effect of Nicorandil on Cardiac Sympathetic Nerve for the Patients of Acute ST Segment Elevation Myocardial Infarction nicorandil, Placebo（normal saline） - Coronary Heart Disease | Phase 4 | Unknown | Xuzhou Central Hospital | 80 | 2021-04-01 | 2021-04-01 |
| Efficacy and Safety of Wen Xin Granules for the Treatment of Unstable Angina Pectoris Wen Xin granule, Clopidogrel Hydrogen Sulfate 75 MG Oral Tablet, Atorvastatin Calcium - Coronary Heart Disease, Unstable Angina | Phase 4 | Unknown | Guang'anmen Hospital of China Academy of Chinese Medical Sciences | 502 | 2021-03-01 | 2021-01-25 |
| Evaluate the Efficacy and Safety of MUSK Pill on Coronary Microvascular Dysfunction MUSK pill - Angina Pectoris, Coronary Heart Disease | Phase 4 | Unknown | Shanghai Hutchison Pharmaceuticals Limited | 264 | 2021-01-28 | 2021-08-02 |
| Efficacy and Safety of Yangxin Shengmai Granules for the Treatment of Stable Angina Pectoris Yangxin Shengmai, Yangxin Shengmai placebo, nitroglycerin tablets - Coronary Heart Disease, Stable Angina | Phase 4 | Unknown | Guang'anmen Hospital of China Academy of Chinese Medical Sciences | 80 | 2020-12-01 | 2020-11-13 |
| Efficacy and Safety of Xueshuanxinmaining Tablet for the Treatment of Stable Angina Pectoris Xueshuanxinmaining tablet, Xueshuanxinmaining placebo, Nitroglycerin tablets - Coronary Heart Disease, Stable Angina | Phase 4 | Unknown | Guang'anmen Hospital of China Academy of Chinese Medical Sciences | 120 | 2020-12-01 | 2020-11-13 |
| Bacillus Calmette-guérin Vaccination to Prevent COVID-19 BCG vaccine, Placebo - COVID-19, Virus Diseases | Phase 4 | Completed | Hellenic Institute for the Study of Sepsis | 301 | 2020-05-26 | 2021-05-11 |
| Comparison Between Propofol and Inhalational Anaesthetic Agents on Cardiovascular Outcomes Following Cardiac Surgery Isoflurane, Sevoflurane or Desflurane, Propofol - Coronary Heart Disease, Cardiovascular Diseases | Phase 4 | Unknown | King's College Hospital NHS Trust | 50 | 2019-11-20 | 2021-02-24 |
| Effect of Empagliflozin on Ventricular Repolarization. Empagliflozin 25 MG - Diabetes Mellitus, Type 2, Coronary Heart Disease | Phase 4 | Completed | University of Sao Paulo | 90 | 2019-10-04 | 2024-05-08 |
| Cardiac Metabolic Modulator Treatment for Improvement of Diastolic Function in Patients With Coronary Heart Disease Trimetazidine - Coronary Heart Disease, Diastolic Dysfunction | Phase 4 | Unknown | China National Center for Cardiovascular Diseases | 226 | 2019-03-25 | 2019-03-25 |
| Different Dosage of Domestic and Imported Clopidogrel on the Platelet Inhibition Ratio in Patients Undergoing PCI Clopidogrel - Coronary Heart Disease | Phase 4 | Unknown | Xijing Hospital | 120 | 2017-01-01 | 2016-12-30 |
Showing 20 of 77. Sign in to see all of them.
Coronary Disease (77) · Atherosclerosis (7) · Angina Pectoris (5) · Angina, Stable (5) · Acute Coronary Syndrome (4) · Cardiovascular Diseases (4) · Diabetes Mellitus, Type 2 (4) · Hypercholesterolemia (4) · Coronary Artery Disease (3) · Diabetes Mellitus (3) · Hyperlipidemias (3) · ST Elevation Myocardial Infarction (3) · Angina, Unstable (2) · Dyslipidemias (2) · Microvascular Angina (2)
Myocardial Ischemia (77) · Vascular Diseases (77) · Heart Diseases (76) · Cardiovascular Diseases (73) · Pathological Conditions, Signs and Symptoms (20) · Nutritional and Metabolic Diseases (13) · Metabolic Diseases (12) · Signs and Symptoms (11) · Chest Pain (10) · Neurologic Manifestations (10) · Pain (10) · Pathologic Processes (10) · Arterial Occlusive Diseases (9) · Arteriosclerosis (9) · Lipid Metabolism Disorders (8)
Clopidogrel (10) · Aspirin (7) · Atorvastatin (6) · Ezetimibe (4) · Simvastatin (4) · Ticagrelor (4) · Nitroglycerin (3) · Rosuvastatin Calcium (3) · Saline Solution (3) · Niacin (2) · Nicorandil (2) · Pioglitazone (2) · Trimetazidine (2) · Acarbose (1) · BCG Vaccine (1)
Deutsches Herzzentrum Muenchen (11) · China National Center for Cardiovascular Diseases (4) · Guang'anmen Hospital of China Academy of Chinese Medical Sciences (4) · Seoul National University Hospital (3) · Organon and Co (2) · Shanghai Hutchison Pharmaceuticals Limited (2) · University of Bern (2) · University of Sao Paulo (2) · Xuzhou Central Hospital (2) · Abant Izzet Baysal University (1) · AstraZeneca (1) · Beijing Anzhen Hospital (1) · Centro de estudios en Cardiologia Intervencionista (1) · Daping Hospital and the Research Institute of Surgery of the Third Military Medical University (1) · Fu Wai Hospital, Beijing, China (1)
China (20) · Germany (13) · Switzerland (5) · South Korea (4) · Canada (3) · Italy (3) · United States (3) · Netherlands (2) · Taiwan (2) · United Kingdom (2) · Argentina (1) · Australia (1) · Austria (1) · Belgium (1) · Brazil (1)
Adnan Kastrati, MD (4) · Albert Schoemig, MD (3) · Julinda Mehilli, MD (3) · Hyo-Soo Kim, MD, PhD (2) · Jun Li, MD (2) · Klaus Tiroch, MD (2) · Stephan Windecker, MD (2) · Alan R. Shuldiner, MD (1) · Alessandro Del Maschio, Med. Doctor (1) · Alf-Aage R. Pettersen, M.D. (1) · Alfredo E Rodriguez, MD PhD FACC (1) · Ana Carolina M Gagliardi, nutritionist (1) · Andrew Pipe, MD (1)
PMID 17898099, PMID 35147767, PMID 10527232, PMID 11426357, PMID 12607706, PMID 15791442, PMID 16105989, PMID 17084252, PMID 17394956, PMID 17868802, PMID 18272504, PMID 18332269, PMID 18402899, PMID 18482661, PMID 18545068, PMID 18559695, PMID 18603748, PMID 18674471, PMID 18955731, PMID 19410683, PMID 19706858, PMID 19720642, PMID 20130232, PMID 20298923, PMID 20339536, PMID 20413733, PMID 20449934, PMID 21185503, PMID 21400652, PMID 21426546, PMID 21646500, PMID 21700254, PMID 21768546, PMID 21816478, PMID 21881565, PMID 21920260, PMID 21951630, PMID 22109997, PMID 22135385, PMID 22141572, PMID 22440496, PMID 22461416, PMID 22463698, PMID 22575316, PMID 22576673, PMID 22584085, PMID 22719784, PMID 22808006, PMID 22883224, PMID 23111421
2019 (1), U01GM074518 (1)