23 completed, 4 unknown, 2 withdrawn, 1 active not recruiting. 30 Phase 3, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 30 | Completed 23, Unknown 4, Withdrawn 2, Active not recruiting 1 |
| Phase 2 | 2 | Completed 2 |
Follow Coronary Heart Disease: new trials by email Literature Review of Coronary Heart Disease trials Research Report on Coronary Heart Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety of Colchicine After PCI Colchicine 0.5 mg, Colchicine 0.375 mg, Placebo - Coronary Heart Disease, Percutaneous Coronary Intervention | Phase 3 | Active not recruiting | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 8862 | 2024-07-09 | 2026-09-03 |
| Efficacy and Safety of Aspirin Therapy With CABG acetylsalicylic acid started for 24 hours before surgery, acetylsalicylic acid stayed for 5 days before surgery - Coronary Heart Disease | Phase 3 | Unknown | Meshalkin Research Institute of Pathology of Circulation | 350 | 2016-01-01 | 2016-10-24 |
| Clinical Trial on the Efficacy and Safety of Sirolimus-Eluting Stent (MiStent® System) MiStent, TIVOLI - Coronary Heart Disease | Phase 3 | Unknown | Micell Technologies | 428 | 2015-07-01 | 2020-09-04 |
| A Clinical Study of Safety and P2Y12 Receptor Inhibition Effects of Ticagrelor and Clopidogrel in Vietnamese Patient 90 mg Ticagrelor, 75mg Clopidogrel - Coronary Heart Disease | Phase 3 | Withdrawn | AstraZeneca | 2013-01-01 | 2013-05-13 | |
| Statin for Depression in Patients Undergoing Coronary Artery Bypass Graft Rosuvastatin, Placebo - Coronary Heart Disease | Phase 3 | Unknown | China National Center for Cardiovascular Diseases | 400 | 2012-06-01 | 2013-08-15 |
| A Study of Dalcetrapib in Patients Hospitalized For An Acute Coronary Syndrome (Dal-ACUTE) dalcetrapib, placebo - Coronary Heart Disease | Phase 3 | Completed | Hoffmann-La Roche | 300 | 2011-03-01 | 2019-07-30 |
| Effect of Remote Ischaemic Preconditioning on Clinical Outcomes in CABG Surgery Remote ischaemic preconditioning, Control - Coronary Heart Disease | Phase 3 | Completed | University College, London | 1612 | 2010-11-01 | 2015-05-29 |
| Optical Coherence Tomography Assessment of Intimal Tissue and Malapposition Biolimus-eluting stent, Everolimus-eluting coronary stent - Coronary Heart Disease | Phase 3 | Unknown | Dr Peter Barlis | 80 | 2010-10-01 | 2014-08-05 |
| Trial of Lycopene/Ateronon for Secondary Prevention of Coronary Heart Disease Ateronon, Placebo - Coronary Heart Disease | Phase 3 | Completed | Brigham and Women's Hospital | 213 | 2009-07-01 | 2014-08-19 |
| Treatment of Coronary Heart Disease With Amiloride Amiloride, Nitrates, clopidogrel, aspirin, statins - Coronary Heart Disease | Phase 2 / Phase 3 | Completed | University of Carabobo | 70 | 2009-02-01 | 2012-06-11 |
| Safety and Efficacy of Mipomersen in Patients With Severe Hypercholesterolemia on a Maximally Tolerated Lipid-Lowering Regimen and Who Are Not on Apheresis Mipomersen, Placebo - Hypercholesterolemia, Coronary Heart Disease | Phase 3 | Completed | Kastle Therapeutics, LLC | 58 | 2009-01-01 | 2016-09-09 |
| Safety and Efficacy of Mipomersen (ISIS 301012) As Add-on Therapy in High Risk Hypercholesterolemic Patients Mipomersen sodium, Placebo - Hypercholesterolemia, Coronary Heart Disease | Phase 3 | Completed | Kastle Therapeutics, LLC | 158 | 2008-11-01 | 2016-09-09 |
| A Study of RO4607381 in Stable Coronary Heart Disease Patients With Recent Acute Coronary Syndrome Dalcetrapib (RO4607381), Evidence-based medical care for Acute Coronary Syndrome, Placebo - Coronary Heart Disease | Phase 3 | Completed | Hoffmann-La Roche | 15871 | 2008-04-01 | 2020-01-03 |
| Safety and Efficacy Study Using ABT-335 (Investigational Drug) in Combination With Atorvastatin, to Study the Effects on Thickening of the Blood Vessel Wall in Patients With Abnormal Lipid (Fat) Levels in the Blood ABT-335, Placebo, Atorvastatin - Coronary Artery Disease, Coronary Heart Disease | Phase 3 | Completed | AbbVie (prior sponsor, Abbott) | 682 | 2008-02-01 | 2018-07-02 |
| Safety and Efficacy Study Comparing ABT-335 Coadministered With Atorvastatin and Ezetimibe to Atorvastatin Coadministered With Ezetimibe in Subjects With Multiple Abnormal Lipid (Fat) Levels in the Blood ABT-335, placebo, atorvastatin - Dyslipidemias, Coronary Heart Disease | Phase 3 | Completed | Abbott | 543 | 2008-02-01 | 2011-06-13 |
| 12-week Open-label, Phase IIIb Comparing Efficacy and Safety of Rosuvastatin (CRESTOR™) in Combination With Ezetimibe Rosuvastatin (Crestor), Ezetimibe, Simvastatin - Hypercholesterolemia, Coronary Heart Disease | Phase 3 | Completed | AstraZeneca | 1743 | 2007-08-01 | 2011-05-13 |
| Treatment of HDL to Reduce the Incidence of Vascular Events HPS2-THRIVE ER niacin/laropiprant, simvastatin, ezetimibe/simvastatin - Cardiovascular Disease, Peripheral Arterial Disease | Phase 3 | Completed | University of Oxford | 25673 | 2007-01-01 | 2014-02-28 |
| Study to Evaluate the Long-Term Safety and Efficacy of ABT-335, in Combination With Three Different Statins in Subjects With Mixed Dyslipidemia. ABT-335 and rosuvastatin calcium, ABT-335 and atorvastatin calcium, ABT-335 and simvastatin - Dyslipidemia, Coronary Heart Disease | Phase 3 | Completed | Abbott | 1911 | 2006-09-01 | 2009-07-23 |
| Follow-on Protocol of Pitavastatin Versus Simvastatin in Patients With Hypercholesterolemia or Dyslipidemia and Coronary Heart Disease Risk Factors pitavastatin, simvastatin - Hypercholesterolemia, Dyslipidemia | Phase 3 | Completed | Kowa Research Europe | 178 | 2006-06-01 | 2010-02-02 |
| Influence Of Omeprazole On The Anti-Platelet Action Of Clopidogrel impact on VASP test - Coronary Heart Disease | Phase 3 | Completed | University Hospital, Brest | 120 | 2006-06-01 | 2008-08-25 |
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Coronary Disease (30) · Dyslipidemias (7) · Hypercholesterolemia (6) · Atherosclerosis (2) · Cardiovascular Diseases (1) · Coronary Artery Disease (1) · Diabetes Mellitus (1) · Diabetes Mellitus, Type 2 (1) · Heart Failure (1) · Hyperglycemia (1) · Motor Activity (1) · Myocardial Ischemia (1) · Peripheral Arterial Disease (1) · Renal Insufficiency (1) · Stroke (1)
Heart Diseases (30) · Vascular Diseases (30) · Cardiovascular Diseases (29) · Myocardial Ischemia (29) · Metabolic Diseases (14) · Nutritional and Metabolic Diseases (14) · Lipid Metabolism Disorders (12) · Hyperlipidemias (6) · Dyslipidemias (5) · Arterial Occlusive Diseases (4) · Arteriosclerosis (4) · Endocrine System Diseases (2) · Glucose Metabolism Disorders (2) · Atherosclerosis (1) · Behavior (1)
2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanoic acid (6) · Rosuvastatin Calcium (6) · Atorvastatin (5) · Simvastatin (5) · Ezetimibe (3) · Clopidogrel (2) · Fenofibrate (2) · dalcetrapib (2) · fenofibric acid (2) · mipomersen (2) · Amiloride (1) · Aspirin (1) · Colchicine (1) · Estrogens, Conjugated (USP) (1) · Ezetimibe, Simvastatin Drug Combination (1)
Abbott (5) · AstraZeneca (4) · Hoffmann-La Roche (2) · Kastle Therapeutics, LLC (2) · AbbVie (prior sponsor, Abbott) (1) · Basque Health Service (1) · Brigham and Women's Hospital (1) · China National Center for Cardiovascular Diseases (1) · Dr Peter Barlis (1) · Kowa Research Europe (1) · Lund University Hospital (1) · Meshalkin Research Institute of Pathology of Circulation (1) · Micell Technologies (1) · Scios, Inc. (1) · Union Hospital, Tongji Medical College, Huazhong University of Science and Technology (1)
United States (14) · United Kingdom (5) · China (4) · Netherlands (4) · Czechia (3) · Spain (3) · Sweden (3) · Argentina (2) · Australia (2) · Brazil (2) · Canada (2) · Denmark (2) · France (2) · Germany (2) · South Africa (2)
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