29 completed. 29 Phase 1, 10 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 29 | Completed 29 |
| Phase 2 | 10 | Completed 10 |
Follow Congestive Heart Failure: new trials by email Literature Review of Congestive Heart Failure trials Research Report on Congestive Heart Failure
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Learn How the Study Treatment BAY1753011 Moves Into, Through and Out of the Body, How it Works, How Safe it is, and How it Affects the Body When Given Once as Tablet in Male and Female Participants With Reduced Kidney Function Compared to Matched Participants With Normal Kidney Function Pecavaptan (BAY1753011) - Congestive Heart Failure, Renal Impairment | Phase 1 | Completed | Bayer | 32 | 2019-11-25 | 2022-10-31 |
| AB-1002 in Patients With Class III Heart Failure 3 x 10e13vg AB-1002 - Congestive Heart Failure, Heart Failure | Phase 1 | Completed | AskBio Inc | 11 | 2019-11-20 | 2026-08-06 |
| An Investigational Study of Experimental Medication BMS-986231 Given in Participants With Different Levels of Liver Function BMS-986231 - Liver Dysfunction, Liver Insufficiency | Phase 1 | Completed | Bristol-Myers Squibb | 76 | 2018-05-25 | 2020-08-27 |
| Phase I Study of OPC-61815 OPC-61815 16mg, OPC-61815 32mg, Moxifloxacin - Congestive Heart Failure | Phase 1 | Completed | Otsuka Pharmaceutical Co., Ltd. | 48 | 2018-05-08 | 2021-05-10 |
| Thiamine Supplementation in Heart Failure: a Pilot Randomized Controlled Crossover Trial Thiamine, Placebo - Heart Failure, Heart Failure With Reduced Ejection Fraction | Phase 1 | Completed | Hamilton Health Sciences Corporation | 24 | 2018-04-02 | 2021-08-31 |
| A Study of Experimental Medication BMS-986231 in Patients With Different Levels of Kidney Function BMS-986231 - Myocardial Failure, Cardiac Failure | Phase 1 | Completed | Bristol-Myers Squibb | 48 | 2018-03-15 | 2019-09-11 |
| Within Subject Variability Study of ER Torsemide 20 mg Tablet in Healthy Subjects Demadex 20mg Tablet, ER Torsemide 20mg Tablet - Congestive Heart Failure, Chronic Kidney Diseases | Phase 1 | Completed | Sarfez Pharmaceuticals, Inc. | 24 | 2017-06-19 | 2018-04-18 |
| AiDing Diuresis wIth Tolvaptan (ADD-IT) Tolvaptan 30 mg + IV Diuretics, Metolazone 5 mg + IV Diuretics, 2.5 times the Diuretics Dose - Cardiomyopathy, Congestive Heart Failure | Phase 1 | Completed | Emory University | 14 | 2016-01-01 | 2019-03-27 |
| A Study Investigating the Safety, Tolerability, and Pharmacokinetics of MTP-131 in Subjects With Congestive Heart Failure MTP-131, Placebo - Congestive Heart Failure | Phase 1 | Completed | Stealth BioTherapeutics Inc. | 36 | 2014-07-01 | 2015-09-17 |
| Autonomic Neural Regulation Therapy to Enhance Myocardial Function in Heart Failure (ANTHEM-HF) Study Vagus Nerve Stimulation (VNS) - Congestive Heart Failure | Phase 1 / Phase 2 | Completed | Cyberonics, Inc. | 60 | 2012-07-01 | 2015-02-19 |
| Tadalafil and Nesiritide as Therapy in Pre-clinical Heart Failure Nesiritide, Tadalafil, Placebo - Congestive Heart Failure | Phase 1 / Phase 2 | Completed | Mayo Clinic | 43 | 2012-02-01 | 2018-03-22 |
| Initial Study of Fenoterol as a Treatment for Heart Failure Oral R,R'-Fenoterol, Oral Racemic Fenoterol - Congestive Heart Failure | Phase 1 | Completed | National Institute on Aging (NIA) | 29 | 2011-07-10 | 2018-07-05 |
| Retrograde Delivery of BMAC (Bone Marrow Aspirate Concentrate) for Congestive Heart Failure BMAC infusion - Congestive Heart Failure | Phase 1 | Completed | Harvest Technologies | 30 | 2011-02-01 | 2014-08-19 |
| Extracorporeal Shockwave Myocardial Revascularization (ESMR) Therapy For The Treatment of Chronic Heart Failure Cardiospec - Congestive Heart Failure | Phase 1 | Completed | Medispec | 9 | 2011-01-01 | 2013-02-20 |
| AC6 Gene Transfer for CHF Ad5.hAC6, Sucrose (3%) - Congestive Heart Failure | Phase 1 / Phase 2 | Completed | Hammond, H. Kirk, M.D. | 56 | 2010-07-01 | 2018-02-09 |
| AutoLogous Human CArdiac-Derived Stem Cell to Treat Ischemic cArdiomyopathy (ALCADIA) human cardiac stem cells - Congestive Heart Failure, Ischemic Cardiomyopathy | Phase 1 | Completed | Naofumi Takehara | 6 | 2010-04-01 | 2015-04-01 |
| Cardiac Stem Cell Infusion in Patients With Ischemic CardiOmyopathy (SCIPIO) Treatment group - Coronary Artery Disease, Congestive Heart Failure | Phase 1 | Completed | University of Louisville | 33 | 2009-02-01 | 2017-04-11 |
| Glycemic Control and Variability for Congestive Heart Failure Exacerbation Intravenous insulin, Subcutaneous insulin - Congestive Heart Failure, Diabetes Mellitus | Phase 1 / Phase 2 | Completed | Kathleen Dungan | 75 | 2009-01-01 | 2013-12-31 |
| Autologous Mesenchymal Stromal Cell Therapy in Heart Failure Mesenchymal stromal cell, Saline - Congestive Heart Failure | Phase 1 / Phase 2 | Completed | Copenhagen University Hospital, Rigshospitalet | 59 | 2008-09-01 | 2015-03-17 |
| Absorption, Distribution, Metabolism and Excretion of [14C]- Labeled BIA 5-453 and Metabolites BIA-5-453 - Hypertension, Congestive Heart Failure | Phase 1 | Completed | Bial - Portela C S.A. | 4 | 2008-09-01 | 2017-01-09 |
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Heart Failure (29) · Cardiomyopathies (2) · Hypertension (2) · Renal Insufficiency (2) · Adenoviridae Infections (1) · Anemia (1) · Arrhythmias, Cardiac (1) · Cardiovascular Diseases (1) · Coronary Artery Disease (1) · Diabetes Mellitus (1) · Heart Failure, Diastolic (1) · Heart Failure, Systolic (1) · Hepatic Insufficiency (1) · Hyperglycemia (1) · Ischemia (1)
Heart Diseases (29) · Cardiovascular Diseases (28) · Pathologic Processes (5) · Pathological Conditions, Signs and Symptoms (5) · Vascular Diseases (4) · Female Urogenital Diseases (3) · Female Urogenital Diseases and Pregnancy Complications (3) · Kidney Diseases (3) · Male Urogenital Diseases (3) · Urogenital Diseases (3) · Urologic Diseases (3) · Chronic Disease (2) · Disease Attributes (2) · Nutritional and Metabolic Diseases (2) · Arterial Occlusive Diseases (1)
Natriuretic Peptide, Brain (3) · Sodium Chloride (2) · etamicastat (2) · Coronary Artery Bypass (1) · Darbepoetin alfa (1) · Diuretics (1) · Extracorporeal Shockwave Therapy (1) · Furosemide (1) · KCB-1 protein, recombinant (1) · Metolazone (1) · Moxifloxacin (1) · Pharmaceutical Preparations (1) · Sucrose (1) · Tablets (1) · Tadalafil (1)
Bial - Portela C S.A. (2) · Bristol-Myers Squibb (2) · Horng Chen (2) · Acusphere (1) · Amgen (1) · AskBio Inc (1) · Bayer (1) · Copenhagen University Hospital, Rigshospitalet (1) · Cyberonics, Inc. (1) · Emory University (1) · Hamilton Health Sciences Corporation (1) · Hammond, H. Kirk, M.D. (1) · Harvest Technologies (1) · Johann Wolfgang Goethe University Hospital (1) · Kathleen Dungan (1)
United States (11) · Germany (3) · India (3) · Japan (2) · Poland (2) · Bulgaria (1) · Canada (1) · Czechia (1) · Denmark (1) · France (1) · Hungary (1) · Israel (1) · Peru (1) · Switzerland (1)
Amit Patel, MD (2) · Horng H. Chen, M.D. (2) · Andreas M Zeiher, MD (1) · Christopher Wilcox, MD, PhD (1) · Clyde W Yancy, MD (1) · David R Murray, MD (1) · Dirk H Walter, MD (1) · Divya Gupta, MD (1) · Eric D Adler, MD (1) · Eric KC Wong, MD FRCPC (1) · Erling B Pedersen, Professor (1) · H. Kirk Hammond, MD (1) · Hilton Miller, Professor (1) · Hiroaki Matsubara, MD,PhD (1)
PMID 11705426, PMID 22088800, PMID 22936827, PMID 22965994, PMID 22980293, PMID 23122795, PMID 23592107, PMID 24444305, PMID 25187002, PMID 25926562, PMID 26601770, PMID 27221316, PMID 27437887, PMID 29217757, PMID 30258648, PMID 31909303, PMID 33590355, PMID 34405565, PMID 35360224, PMID 41120766
P01HL076611 (3), UL1RR024150 (3), R01HL084155 (2), 2005 (1), 2017 (1), 2019 (1), P01HL066941 (1), R01HL036634 (1), R21DK081877 (1)