34 completed, 6 unknown, 5 recruiting, 4 terminated. 58 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 58 | Completed 34, Unknown 6, Recruiting 5, Terminated 4, Withdrawn 4, Active not recruiting 2, Enrolling by invitation 2, Not yet recruiting 1 |
Follow Concussion, Mild: new trials by email Literature Review of Concussion, Mild trials Research Report on Concussion, Mild
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Use of Tinted Contact Lenses for Concussion-Related Light Sensitivity Narrow band (tinted) contact lenses, broad band (clear) contact lenses - Concussion, Mild, Photophobia | Not applicable | Recruiting | University of Alabama at Birmingham | 60 | 2026-05-08 | 2026-06-11 |
| Female Concussion Head Cooling Brain Cooling - Concussion (Diagnosis), Concussion Post Syndrome | Not applicable | Not yet recruiting | Penn State University | 32 | 2026-01-15 | 2025-12-26 |
| Acceptance and Commitment Therapy Integrated Vestibular Rehabilitation (ACTIVE) RCT Acceptance and Commitment Therapy Integrated Rehabilitation (ACT), Usual Care Rehabilitation - Concussion, Mild, Mild Traumatic Brain Injury (mTBI) | Not applicable | Recruiting | University of Pittsburgh | 250 | 2025-02-27 | 2026-06-30 |
| Pro-2-Cool Pivotal Trial II Pro2Cool Device, Sham Cooling Garment Device - Concussion, Mild | Not applicable | Recruiting | TecTraum Inc. | 66 | 2025-02-20 | 2026-08-12 |
| SMART-CPT for PTSD/Concussion Implementation SMART-CPT, CPT - PTSD, Concussion, Mild | Not applicable | Enrolling by invitation | San Diego Veterans Healthcare System | 124 | 2024-12-01 | 2025-06-04 |
| Improving In-hospital and Post-discharge Patient Education for Mild Traumatic Brain Injury Clinical implementation strategies - Concussion, Mild, Traumatic Brain Injury | Not applicable | Enrolling by invitation | Medical College of Wisconsin | 5831 | 2024-09-11 | 2026-10-30 |
| RTL Concussion Communication InjureFree - Concussion, Mild, Post Concussion Symptoms | Not applicable | Withdrawn | University of Florida | 2024-08-28 | 2024-10-23 | |
| Impact of a Paced Breathing Exercise Intervention on Autonomic Nervous System Function After Pediatric Concussion Breathing exercises - Concussion, Mild | Not applicable | Unknown | McGill University Health Centre/Research Institute of the McGill University Health Centre | 20 | 2024-06-01 | 2024-10-01 |
| Facilitating Access to Specialty Treatment RPM-assisted specialist access - Mild Traumatic Brain Injury, Concussion, Mild | Not applicable | Recruiting | Children's Hospital of Philadelphia | 210 | 2024-03-11 | 2026-05-22 |
| Non-invasive Brain Stimulation and Injury Risk Biomechanics Repetitive Transcranial Magnetic Stimulation (Theta Burst Stimulation) - Concussion, Mild | Not applicable | Completed | University of Georgia | 40 | 2023-11-03 | 2025-01-09 |
| Eye Recovery Automation for Post Injury Dysfunction (iRAPID) Virtual Eye Rotation Vision Exercise (VERVE), Sham VR Therapy - Convergence Insufficiency, Traumatic Brain Injury | Not applicable | Recruiting | New Jersey Institute of Technology | 100 | 2023-10-23 | 2026-04-14 |
| Impact of Instability Training on Vestibular Dysfunction in Postconcussion Combat Athletes Traditional Physical therapy, Instability training - Concussion, Mild | Not applicable | Completed | Riphah International University | 36 | 2023-10-23 | 2026-07-28 |
| Concussion Treatment in Older Adults Behavioral Control, Targeted Intervention - Concussion, Mild | Not applicable | Completed | University of Pittsburgh | 56 | 2023-09-07 | 2026-08-06 |
| GAIN Symptoms: Post-traumatic Headache Active repetitive transcranial magnetic stimulation (rTMS), Sham repetitive transcranial magnetic stimulation (rTMS) - Post-Traumatic Headache, Concussion, Mild | Not applicable | Active not recruiting | University of Aarhus | 62 | 2023-08-28 | 2026-05-01 |
| Omega-3 Treatment for Concussion in Adolescents Omega-3, Placebo - Concussion, Mild | Not applicable | Unknown | University of Manitoba | 140 | 2023-06-01 | 2023-06-23 |
| Building Emotional Self-Awareness Teletherapy (BEST) Treatment - Concussion, Mild, Concussion, Brain | Not applicable | Completed | Indiana University | 40 | 2023-02-23 | 2025-04-01 |
| The Exercise and Concussion Health Study Aerobic Exercise, Balance Exercise - Concussion, Mild, Concussion, Brain | Not applicable | Completed | Northeastern University | 37 | 2023-02-01 | 2026-01-07 |
| Acute Nerve Stimulation For Enhancing Human and Cognitive Performance Experimental group with 100% intensity setting on Apollo Neuro device, Active Comparator group with 10% intensity setting on the Apollo Neuro device - Concussion, Mild, Autonomic Nervous System | Not applicable | Completed | University of South Carolina | 35 | 2023-01-15 | 2024-03-28 |
| Mindfulness-Based Intervention for Mild Traumatic Brain Injury Mindfulness-Based Intervention, Cognitive Sham + Usual Care - Concussion, Mild | Not applicable | Completed | Children's Hospital of Eastern Ontario | 99 | 2022-10-04 | 2025-02-28 |
| Cooling Helmets to Decrease Concussion Symptoms Catalyst Cryohelmet - Concussion, Mild, TBI (Traumatic Brain Injury) | Not applicable | Terminated | Corewell Health South | 18 | 2022-06-23 | 2024-11-29 |
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Brain Concussion (58) · Brain Injuries, Traumatic (10) · Post-Concussion Syndrome (5) · Ocular Motility Disorders (4) · Brain Injuries (2) · Disease (2) · Emergencies (2) · Parasomnias (2) · Post-Traumatic Headache (2) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (2) · Psychological Well-Being (2) · Stress Disorders, Post-Traumatic (2) · Affective Symptoms (1) · Cognitive Dysfunction (1) · Communication (1)
Brain Diseases (58) · Central Nervous System Diseases (58) · Craniocerebral Trauma (58) · Head Injuries, Closed (58) · Nervous System Diseases (58) · Trauma, Nervous System (58) · Wounds and Injuries (58) · Wounds, Nonpenetrating (58) · Brain Injuries (56) · Brain Injuries, Traumatic (48) · Pathological Conditions, Signs and Symptoms (7) · Behavior (6) · Mental Disorders (6) · Eye Diseases (5) · Pathologic Processes (5)
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Children's Hospital Medical Center, Cincinnati (6) · University of Pittsburgh (4) · Indiana University (3) · University of Alabama at Birmingham (3) · Corewell Health South (2) · New Jersey Institute of Technology (2) · University of Arizona (2) · Boston Children's Hospital (1) · Children's Hospital of Eastern Ontario (1) · Children's Hospital of Philadelphia (1) · Children's National Research Institute (1) · Danish College of Optometry and Vision Science (1) · Danish Headache Center (1) · Dr. Michael Esser (1) · Henry M. Jackson Foundation for the Advancement of Military Medicine (1)
United States (40) · Canada (9) · Denmark (3) · Pakistan (2) · Finland (1) · United Kingdom (1)
Gregory D Myer, PhD (6) · Anthony Kontos, PhD (2) · Aimun Jamjoom, FRCS (1) · Anne W Hunt, PhD (1) · Anthony P Kontod, PhD (1) · Anthony P Kontos, PhD (1) · Becky Luu, OD (1) · Brent A Bauer, MD (1) · Brian Reilly, MD (1) · Candice I Turner, OD (1) · Chang Yaramothu, PhD (1) · Chantel T Debert, MD MSc (1) · Chris Trigger, DO (1) · Daniel J Corwin, MD, MSCE (1)
PMID 21074078, PMID 23479479, PMID 34104033, PMID 34320557, PMID 35473570, PMID 36149737, PMID 36724010, PMID 37456641, PMID 38602770, PMID 38904136, PMID 39504933, PMID 39546477, PMID 40255022, PMID 40293595, PMID 41033748, PMID 41037445, PMID 41817527, PMID 42824171
I21RX001608 (1), K23NS128275 (1), R01EY023261 (1), R01HD094722 (1), R49CE003087 (1)