45 completed, 13 unknown, 10 recruiting, 5 not yet recruiting. 58 Not applicable, 2 Phase 4, 1 Phase 1, 1 Phase 2, 1 Phase 3.
Follow Affective Symptoms: new trials by email Literature Review of Affective Symptoms trials Research Report on Affective Symptoms
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Assessment of the Frequency of Functional Neurological Disorders in Multiple Sclerosis and Analysis of Clinical and Psychological Determinants Functional Neurological Disorders, Multiple Sclerosis | Not yet recruiting | University Hospital, Strasbourg, France | 100 | 2026-10-02 | 2026-10-07 | |
| Pilot Trial for Health Products on Mood and Sleep Quality Vita Calm Mood Booster Formula (VCMBF), Vita Calm Deep Sleep Formula (VCDSF), Placebo - Sleep Disturbance, Emotional Disturbance | Not applicable | Recruiting | The University of Hong Kong | 60 | 2026-09-22 | 2026-10-02 |
| Effect of Alexithymia on Treatment Response to Transforaminal Epidural Steroid Injections in Chronic Low Back Pain Psychometric Assessment and Clinical Follow-up Battery - Chronic Low Back Pain, Radiculopathy | Not yet recruiting | Marmara University | 60 | 2026-09-01 | 2026-09-18 | |
| Alexithymia, Pain Intensity, Quality of Life, and Psychological Symptoms in Chronic Coccydynia Patients Scheduled for Ganglion Impar Block Psychometric and Clinical Survey Battery - Coccydynia, Chronic Pain | Not yet recruiting | Marmara University | 70 | 2026-09-01 | 2026-09-18 | |
| Body-Focused Mindfulness as an Add-on Intervention in Inpatient Alcohol Use Disorder Treatment (MBI-AUD-PL) Body-Focused Mindfulness Intervention, Standard Psychoeducation - Alcohol Use Disorder (AUD), Alcohol-Related Disorders | Not applicable | Recruiting | Medical University of Warsaw | 240 | 2026-07-01 | 2026-08-24 |
| Interoceptive Awareness and Dream Themes Adult Women | Active not recruiting | Recep Tayyip Erdogan University | 307 | 2026-07-01 | 2026-07-21 | |
| Evaluation of Alexithymia in Chronic Pain Patients With Spinal Cord Stimulation Psychometric Questionnaires and Retrospective Data Collection - Chronic Pain | Recruiting | Marmara University | 20 | 2026-06-01 | 2026-08-12 | |
| Clinical Trial Comparing the Efficacy of Two Teletherapy Programs at Improving Psychological Health in People With Brain Injury Program 1, Program 2 - Mild Traumatic Brain Injury, Alexithymia | Not applicable | Recruiting | Hackensack Meridian Health | 300 | 2026-05-20 | 2026-06-12 |
| Evaluation of Alexithymia and Its Relationship With Clinical Parameters in Patients With Chronic Coccydynia Chronic Coccydynia, Alexithymia | Recruiting | Marmara University | 15 | 2026-03-20 | 2026-08-12 | |
| Film-Based Medical Education and Social Justice Course: Effects on Alexithymia and Empathy in Medical Students Film-Based Medical Education and Social Justice Elective - Alexithymia, Empathy Skills | Not applicable | Enrolling by invitation | Çanakkale Onsekiz Mart University | 60 | 2026-02-16 | 2026-02-25 |
| No Time to Wait: Single Session Intervention Online Single Session Intervention on Growth Mindset - Depression - Major Depressive Disorder, Anxiety | Not applicable | Recruiting | United Christian Hospital | 124 | 2026-01-10 | 2026-08-26 |
| Interoceptive Awareness, Physical Activity, Body Awareness and Emotional Status in Individuals With Non-Specific Chronic Low Back Pain Lower Back Pain Chronic, Non Specific Chronic Low Back Pain | Not yet recruiting | Istinye University | 130 | 2026-01-01 | 2025-12-16 | |
| Alexithymia and Emotional Dysregulation in a Cohort of Pediatric Patients With Epilepsy Alexithymia, Epilepsies | Recruiting | Istituto Giannina Gaslini | 100 | 2025-12-09 | 2026-10-19 | |
| Haptic Feedback for Improved Interoceptive Awareness and Mental Well-being Heart rate feedback from smartwatch - Interoceptive Awareness, Interoception | Not applicable | Completed | Massachusetts Institute of Technology | 29 | 2025-06-26 | 2026-09-09 |
| AI-assisted GNW on Adolescent Emotional Distress AI-GNW, NF-GNW, NWG - Emotional Disturbance, Emotional Regulation | Not applicable | Completed | Peking University | 486 | 2025-05-19 | 2026-06-10 |
| Survey of Psychological Well-being of Health Care Workers in the Hospital Setting Psychological Assessment - Healthy, Psychological Well Being | Not yet recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 500 | 2025-04-01 | 2025-04-27 | |
| Evaluation of a Trauma-Informed Partner Violence Intervention Program SAH, TAU - Domestic Violence, Post Traumatic Stress Disorder | Not applicable | Enrolling by invitation | Boston University | 1000 | 2025-02-13 | 2026-10-01 |
| Family Connections Behavioral Treatment - Emotional Disturbance, Behavior Disorders in Children | Not applicable | Recruiting | Cambridge Health Alliance | 300 | 2025-01-30 | 2026-10-22 |
| Neurobehavioral Affective Control Training Neurobehavioral Affective Control Training - Emotional Distress, Impulsive Behavior | Not applicable | Completed | University of California, Berkeley | 50 | 2024-11-22 | 2026-02-20 |
| Visuospatial and Affective Abilities in Parkinson Disease Prismatic adaptation, Schirmer test - Parkinson Disease, Alexithymia | Not applicable | Enrolling by invitation | IRCCS Centro Neurolesi Bonino Pulejo | 126 | 2024-04-30 | 2026-02-24 |
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Depression (17) · Emotional Regulation (11) · Anxiety Disorders (10) · Mental Disorders (7) · Chronic Pain (4) · Learning Disabilities (4) · Multiple Sclerosis (4) · Diabetes Mellitus (3) · Motor Activity (3) · Alcoholism (2) · Anorexia Nervosa (2) · Behavioral Symptoms (2) · Bipolar Disorder (2) · Brain Concussion (2)
Behavior (84) · Behavioral Symptoms (82) · Mental Disorders (30) · Nervous System Diseases (23) · Pathological Conditions, Signs and Symptoms (20) · Signs and Symptoms (18) · Neurologic Manifestations (12) · Social Behavior (12) · Self-Control (10) · Brain Diseases (8) · Central Nervous System Diseases (8) · Nutritional and Metabolic Diseases (6) · Communication Disorders (5) · Immune System Diseases (5) · Neurobehavioral Manifestations (5)
Exercise (2) · Nutritional Status (2) · Therapeutics (2) · Art Therapy (1) · Autogenic Training (1) · Behavior Therapy (1) · Cognitive Behavioral Therapy (1) · Fentanyl (1) · Gene Expression (1) · Hypnosis (1) · Interviews as Topic (1) · Laughter Therapy (1) · Mentalization-Based Therapy (1) · Mindfulness-Based Stress Reduction (1) · Morphine (1)
Columbia University (4) · Marmara University (4) · Cambridge Health Alliance (2) · Indiana University (2) · Istanbul Medeniyet University (2) · Lund University (2) · Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey (2) · University of Roma La Sapienza (2) · University of Zurich (2) · Alexandria University (1) · American Institutes for Research (1) · Ankara Medipol University (1) · Association pour le Développement et l'Organisation de la Recherche en Pneumologie et sur le Sommeil (1) · AstraZeneca (1) · Atlas University (1)
United States (28) · Turkey (Türkiye) (14) · France (8) · Italy (6) · Norway (4) · Germany (3) · Russia (3) · Belgium (2) · Hong Kong (2) · Switzerland (2) · Austria (1) · Canada (1) · China (1) · Egypt (1) · Greece (1)
Eva O Melin, MD (2) · Flora Hammond, MD (2) · Martha G Welch, MD (2) · Martha Welch, MD (2) · Aanand D Naik, MD BA (1) · Alexandra Heringh, MD (1) · Alina D Aizenshtein (1) · Amit Etkin, M.D., Ph.D. (1) · Andrzej Jakubczyk, MD, PhD (1) · Andy Garbacz, PhD (1) · Attila Nemeth, MD PHD (1)
PMID 22828177, PMID 24685661, PMID 24774351, PMID 25147733, PMID 25552674, PMID 25893651, PMID 26787360, PMID 27121185, PMID 27437646, PMID 27872390, PMID 28060205, PMID 28715907, PMID 28715908, PMID 29890960, PMID 30112603, PMID 31390035, PMID 32160891, PMID 33728989, PMID 36703250, PMID 37653536, PMID 38323949, PMID 39816857, PMID 39970439, PMID 41042725, PMID 41738474, PMID 42338028
P30MH097488 (1), R01MD012770 (1), R41HD077967 (1), U01PS003304 (1)