778 completed, 170 recruiting, 153 unknown, 74 not yet recruiting. 957 Not applicable, 47 Phase 2, 29 Phase 1, 18 Phase 3, 5 Phase 4.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| OPTIMAL LEAP: Optimizing Dihydroartemisinin-Piperaquine IPTsc Intervals to Advance Learning, Executive Function, Attendance, and Antimalarial Resistance Surveillance in Kenyan Schoolchildren Monthly DP, Quarterly DP - Malaria, Asymptomatic Malaria | Phase 3 | Not yet recruiting | Indiana University | 1500 | 2028-01-01 | 2026-09-01 |
| TeamTalk: Improving Inter-professional Communication During Cancer Treatment Multi-level communication intervention - Pediatric Cancer | Not applicable | Not yet recruiting | Washington University School of Medicine | 8 | 2027-09-23 | 2026-01-07 |
| Evaluating Food Messaging Campaigns for Young Adults Counter-marketing, Health education, Control (neutral) messages - Social Media, Diet Quality | Not applicable | Not yet recruiting | Stanford University | 750 | 2027-09-01 | 2026-08-17 |
| Reciprocal Innovation to Optimize Low-Tech Augmentative and Alternative Communication (AAC) for Individuals Automated AAC Assessment and Low-Tech AAC Implementation Support, Standard AAC Support - Autism, Neurodevelopment | Not applicable | Not yet recruiting | Indiana University | 500 | 2027-06-01 | 2026-05-12 |
| Virtual Communication in the Hospital: Impact on Patients and Surrogates VCHIPS - Communication, Anxiety | Not applicable | Withdrawn | Indiana University | 2027-03-31 | 2026-04-22 | |
| Simulation on the Enhancement of Clinical Communication Competencies in Nursing Students Clinical Simulation - Communication | Not applicable | Not yet recruiting | Escola Superior de Saúde Norte da Cruz Vermelha Portuguesa | 50 | 2027-02-01 | 2026-07-28 |
| Evaluation of a Novel Quantum-Inspired Intervention (QII) for Children With Autism Spectrum Disorder: A Global Confirmatory Study Quantum-Inspired Intervention (QII) - Autism Spectrum Disorder, Autism Spectrum Disorder (ASD | Not applicable | Not yet recruiting | BlissBot, Inc | 80 | 2027-02-01 | 2026-10-27 |
| Dance, Yoga, And Mindful Movement Training For ASD Yoga, dance and Mindful Movement - Autism Spectrum Disorder, Autism Spectrum Disorder (ASD) | Not applicable | Not yet recruiting | USC Glorya Kaufman School of Dance | 40 | 2027-01-17 | 2026-08-12 |
| Young Adult Food Messaging Experiment Lying about unhealthy foods being healthy, Engineering foods to be addictive, Targeting groups - Diet Quality, Young Adult Health | Not applicable | Not yet recruiting | Stanford University | 645 | 2027-01-08 | 2026-08-17 |
| Self-Concept Reinforcement for Early School Readiness Self-Concept Reinforcement for Early School Readiness, Reach Out and Read - Child Behavior, Child Behavior Problem | Not applicable | Not yet recruiting | Children's Hospital Los Angeles | 134 | 2027-01-01 | 2026-10-20 |
| Trial of Center-Based Early Start Denver Model vs. Pivotal Response Treatment in Children With Autism Early Start Denver Model (ESDM), Pivotal Response Treatment (PRT), Developmental Reciprocity Treatment (DRT) - Autism Spectrum Disorder (ASD), Autism | Not applicable | Not yet recruiting | Stanford University | 140 | 2027-01-01 | 2026-11-05 |
| Neural Mechanisms for Stopping Ongoing Speech Production (Study 2) Speech Production Tasks - Epilepsy, Speech | Not applicable | Enrolling by invitation | University of Pittsburgh | 12 | 2027-01-01 | 2026-11-05 |
| IGNITE-TX Phase III: (Identifying Individuals for Genetic Testing & Treatment) Intervention IGNITE-TX program, Genetic Counseling and Testing - Communication, Informed Decision-making | Phase 3 | Not yet recruiting | M.D. Anderson Cancer Center | 2100 | 2026-12-01 | 2026-07-17 |
| Haptics in Virtual Reality Haptic-Integrated Interactive Virtual Reality Experience, Traditional Virtual Reality Experience (Hand Controllers) - Literacy, Literacy-language Intervention | Not applicable | Recruiting | University of Miami | 60 | 2026-12-01 | 2026-08-17 |
| Study of Psychoeducation and Reading for Kids (SPARK) Psychoeducational tutoring - Reading Difficulties, Behavioral Problems | Not applicable | Not yet recruiting | State University of New York - Upstate Medical University | 40 | 2026-11-07 | 2026-11-06 |
| Effectiveness, Acceptability and Feasibility of a Communication and Care Coordinator (CCC) Model in Facilitating Serious Illness Communication (SIC) and Care in Patients With Cancer CCC Intervention - Cancer | Not applicable | Recruiting | National Cancer Centre, Singapore | 560 | 2026-11-05 | 2026-11-10 |
| Validation of the Healthcare Relationship Assessment Scale (ERA) in Health Sciences Students. ERA Scale (Healthcare Relationship Assessment Scale) - Health Adult Subjects, Communication | Not yet recruiting | Universidad Loyola Andalucia | 300 | 2026-11-01 | 2026-11-06 | |
| IN-TALK: Co-producing a Hospice Intimacy Support Toolkit in England Experience-Based Co-Design (EBCD) workshops - Communication About Intimacy Needs in Hospice and Palliative Care | Not yet recruiting | Dorothy House Hospice | 794 | 2026-11-01 | 2026-11-06 | |
| Examining the Impact of a Patient Communication Pathway in the Critical Care Setting on Patient Experience and Nursing Staff's Perceptions of Usability Evidence-based communication protocol associated low and high-tech communication approaches (i.e. Vidatalk) - Communication Barriers | Not applicable | Not yet recruiting | University of Colorado, Denver | 300 | 2026-10-31 | 2026-10-27 |
| Pediatric Research in the Outpatient Setting CoHort Parental Stress, Communication Disorder, Childhood | Recruiting | Insel Gruppe AG, University Hospital Bern | 200 | 2026-10-26 | 2026-11-05 |
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Speech (188) · Language (183) · Literacy (94) · Autism Spectrum Disorder (71) · Neoplasms (62) · Stroke (57) · Aphasia (56) · Anxiety Disorders (48) · Autistic Disorder (44) · Behavior (43) · Narration (39) · Depression (38) · Crying (37) · Cell Phone Use (35)
Behavior (1284) · Pathological Conditions, Signs and Symptoms (357) · Nervous System Diseases (316) · Mental Disorders (284) · Signs and Symptoms (257) · Neurologic Manifestations (234) · Verbal Behavior (213) · Central Nervous System Diseases (170) · Brain Diseases (162) · Neurobehavioral Manifestations (158) · Neurodevelopmental Disorders (147) · Nonverbal Communication (127) · Communication Disorders (117) · Pathologic Processes (113)
Surveys and Questionnaires (27) · Laughter Therapy (17) · Transcranial Direct Current Stimulation (12) · Standard of Care (11) · Speech Therapy (10) · Educational Status (9) · Therapeutics (8) · Focus Groups (7) · Methods (7) · Acclimatization (6) · Exercise (6) · Cognitive Behavioral Therapy (5) · Control Groups (5) · Interviews as Topic (5) · Magnetic Resonance Imaging (5)
University of Wisconsin, Madison (22) · VA Office of Research and Development (16) · Johns Hopkins University (15) · University of Pittsburgh (13) · The University of Hong Kong (12) · University of Chicago (12) · Duke University (11) · Stanford University (11) · University of Florida (11) · University of Pennsylvania (11) · Memorial Sloan Kettering Cancer Center (10) · Northwestern University (10) · Rutgers, The State University of New Jersey (10) · Indiana University (9) · National Institute of Neurological Disorders and Stroke (NINDS) (9)
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David Ostry (7) · Emil Fristed, MSc (7) · Amir Goren, PhD (5) · Rebecca Landa, PhD, CCC-SLP (5) · Carrie Niziolek, PhD (4) · Manuel E Jimenez, MD, MS (4) · Connie Kasari, Ph.D. (3) · Deanna Kepka, PhD, MPH (3) · Edward F Chang, MD (3) · Elizabeth Miller, MD, PhD (3) · Henry W Mahncke, PhD (3) · Maureen E Lyon, PhD (3) · Sebastian Walther, MD (3) · Amy D. Rodriguez, PhD (2) · Amy Wetherby, PhD (2)
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R01DC017476 (6), R21DC021024 (5), R01AG055425 (4), R01DC019134 (4), R01DC022097 (4), R01CA279973 (3), R01DC017439 (3), 2017 (2), P01AG055365 (2), R01DC013315 (2), R01DK142823 (2), R01MH117998 (2), R21NR018693 (2), 1RF1AG050967-01A1 (1), 1UG1CA189823-01 (1)