4 recruiting, 3 completed, 2 unknown, 1 terminated. 10 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 10 | Recruiting 4, Completed 3, Unknown 2, Terminated 1 |
| Phase 1 | 2 | Completed 1, Recruiting 1 |
Follow Concussion, Brain: new trials by email Literature Review of Concussion, Brain trials Research Report on Concussion, Brain
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| BCAAs in Concussion 3.0 BCAA, Placebo - Concussion (Diagnosis), MTBI - Mild Traumatic Brain Injury | Phase 2 | Recruiting | Akiva Cohen | 150 | 2026-08-05 | 2026-09-03 |
| BCAAs in Concussion 2.0 BCAA, Placebo - Concussion, Brain, Concussion, Mild | Phase 2 | Completed | Akiva Cohen | 17 | 2025-04-01 | 2026-09-03 |
| Personalized Brain Stimulation to Treat Chronic Concussive Symptoms Active cTBS, Inactive/Sham cTBS, Imaginal exposure - Post-Concussion Syndrome, Concussion, Brain | Phase 2 | Recruiting | University of California, Los Angeles | 75 | 2024-03-06 | 2026-02-24 |
| Pathways Relating Amnestic MCI to a Mild Traumatic Brain Injury History High Definition Transcranial Direct Current Stimulation - Mild Cognitive Impairment, Amnestic Mild Cognitive Disorder | Phase 2 | Recruiting | University of Texas Southwestern Medical Center | 75 | 2023-04-20 | 2026-07-20 |
| Acute Concussion and Melatonin Melatonin 3 MG, Placebo - Concussion, Mild, Concussion, Brain | Phase 2 | Unknown | Children's National Research Institute | 254 | 2023-03-01 | 2024-02-07 |
| Modulating Exercise Dosage to Improve Concussion Recovery High Dose Exercise - Concussion, Brain, Treatment | Phase 1 / Phase 2 | Recruiting | University of Colorado, Denver | 178 | 2022-08-05 | 2026-08-31 |
| Ghrelin (OXE--103) for Acute Concussion Management Ghrelin (OXE-103), Placebo - Concussion, Brain, Traumatic Brain Injury | Phase 2 | Completed | Michael Rippee | 23 | 2020-10-20 | 2024-05-21 |
| Growth Hormone Replacement Therapy for Retried Professional Football Players Growth Hormone, Placebo - TBI (Traumatic Brain Injury), Concussion, Brain | Phase 2 | Unknown | Center for Neurological Studies | 42 | 2019-10-08 | 2023-02-08 |
| Sildenafil Treatment for Mild TBI Sildenafil Citrate, Placebo oral capsule - Vascular System Injuries, Concussion, Brain | Phase 2 | Terminated | University of Texas Southwestern Medical Center | 22 | 2018-07-25 | 2020-11-19 |
| rTMS Treatment of Persistent Headache and Post Concussion Symptoms Attributed to Mild Traumatic Injury to the Head rTMS - Real Air Film Coil, rTMS - Sham Coil - Brain Injuries, Traumatic, Concussion, Brain | Phase 1 / Phase 2 | Completed | University of Calgary | 20 | 2017-04-15 | 2019-04-22 |
Brain Concussion (10) · Brain Injuries, Traumatic (3) · Anxiety Disorders (2) · Depression (2) · Headache (2) · Post-Concussion Syndrome (2) · Autonomic Nervous System Diseases (1) · Cognition Disorders (1) · Cognitive Dysfunction (1) · Craniocerebral Trauma (1) · Disease (1) · Dizziness (1) · Dwarfism, Pituitary (1) · Headache Disorders (1) · Hypopituitarism (1)
Brain Diseases (10) · Brain Injuries (10) · Central Nervous System Diseases (10) · Head Injuries, Closed (10) · Nervous System Diseases (10) · Trauma, Nervous System (10) · Wounds and Injuries (10) · Wounds, Nonpenetrating (10) · Craniocerebral Trauma (9) · Brain Injuries, Traumatic (7) · Mental Disorders (4) · Pathological Conditions, Signs and Symptoms (4) · Pathologic Processes (3) · Behavior (2) · Behavioral Symptoms (2)
Exercise (1) · Ghrelin (1) · Growth Hormone (1) · Human Growth Hormone (1) · Implosive Therapy (1) · Injections (1) · Melatonin (1) · Sildenafil Citrate (1) · Transcranial Magnetic Stimulation (1)
Akiva Cohen (2) · University of Texas Southwestern Medical Center (2) · Center for Neurological Studies (1) · Children's National Research Institute (1) · Michael Rippee (1) · University of Calgary (1) · University of California, Los Angeles (1) · University of Colorado, Denver (1)
United States (9) · Canada (1)
Daniel Corwin, MD (2) · Chantel Debert, MD MSc FRCPC (1) · David R Howell, PhD (1) · Michael Rippee, MD (1) · Randall R Benson, MD (1)
PMID 31530227, PMID 38468511, PMID 39760650, PMID 40297050, PMID 40887012, PMID 40990413, PMID 41019467, PMID 41593831, PMID 41622533, PMID 41956449, PMID 42245142, PMID 42284615
R01HD108133 (1)