49 completed, 21 unknown, 16 recruiting, 5 enrolling by invitation. 60 Not applicable, 10 Phase 2, 3 Phase 1, 1 Early Phase 1.
Follow Concussion, Brain: new trials by email Literature Review of Concussion, Brain trials Research Report on Concussion, Brain
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| BCAAs in Concussion 3.0 BCAA, Placebo - Concussion (Diagnosis), MTBI - Mild Traumatic Brain Injury | Phase 2 | Recruiting | Akiva Cohen | 150 | 2026-08-05 | 2026-09-03 |
| EXercise-induced PhysioLogical Adaptations In Neurological Disorders Acute Exercise - Epilepsy, Functional Neurological Disorder | Not applicable | Recruiting | Brigham and Women's Hospital | 240 | 2026-07-22 | 2026-10-20 |
| Ecological Test Standardization for Concussion Assessment in Football Players Ecological Dual-Task Cognitive Assessment, Visuospatial Working Memory Ecological Test - Concussion, Brain, Sports-related Concussion | Not applicable | Recruiting | Centre Mutualiste de Rééducation et de Réadaptation Fonctionnelles de Kerpape | 100 | 2026-04-13 | 2026-08-27 |
| REhabilitation of MEMory Symptoms After BRain Concussion Cognitive behavioral therapy, Cognitive rehabilitation - Concussion, Brain, Mild Traumatic Brain Injury | Not applicable | Recruiting | University of British Columbia | 184 | 2025-07-02 | 2026-06-02 |
| BCAAs in Concussion 2.0 BCAA, Placebo - Concussion, Brain, Concussion, Mild | Phase 2 | Completed | Akiva Cohen | 17 | 2025-04-01 | 2026-09-03 |
| Turkish Translation of SportsConcussion Assesment Tool 6 SCAT6-tr - Sports Injury, Concussion, Mild | Active not recruiting | Ordu University | 30 | 2024-09-15 | 2025-08-19 | |
| Feasibility of Aerobic Exercise for Recovery From Work-related Concussion Target Heartrate Aerobic Exercise - Concussion, Brain | Not applicable | Completed | State University of New York at Buffalo | 11 | 2024-07-01 | 2026-10-28 |
| The Impact of Eye and Body Training on the Injury Rate of Concussions in Female Soccer Players Training recommendation - Concussion, Brain, Musculoskeletal Pain | Not applicable | Unknown | BrainCare Medical Group | 209 | 2024-06-30 | 2024-06-25 |
| A Pragmatic Rehabilitation Intervention: The Active Rehab Study Active Rehab (Group 2), Progressive Return to Activity (Group 1) - Concussion, Brain | Not applicable | Active not recruiting | University of North Carolina, Chapel Hill | 63 | 2024-06-04 | 2026-11-09 |
| CBT-I vs. MBTI for Traumatic Brain Injury (TBI)-Related Insomnia and Post-Traumatic Stress Symptoms Mindfulness-based treatment for insomnia (MBTI), Cognitive behavioral therapy for insomnia (CBT-I) - Traumatic Brain Injury, Insomnia | Not applicable | Recruiting | Johns Hopkins University | 360 | 2024-05-10 | 2026-07-13 |
| The COSP-RBD Study: Concussions and Contact Sports in RBD vs Controls Exposure to contact sports or history of concussions - REM Sleep Behavior Disorder, Concussion, Brain | Recruiting | Guy's and St Thomas' NHS Foundation Trust | 140 | 2024-04-23 | 2026-06-04 | |
| Personalized Brain Stimulation to Treat Chronic Concussive Symptoms Active cTBS, Inactive/Sham cTBS, Imaginal exposure - Post-Concussion Syndrome, Concussion, Brain | Phase 2 | Recruiting | University of California, Los Angeles | 75 | 2024-03-06 | 2026-02-24 |
| The Influence of Prescribed Exercise on Pain Related Fear Following Concussion in Collegiate Athletes Treadmill Walking - Concussion, Brain | Not applicable | Recruiting | University of Virginia | 46 | 2024-02-27 | 2024-12-09 |
| Creatine Supplementation in Concussion Recovery Creatine - Concussion, Brain | Not applicable | Recruiting | San Diego State University | 20 | 2024-02-01 | 2026-06-18 |
| Addressing Sleep in Adolescents Post-Concussion ("ASAP Study") Brief Sleep Intervention - Concussion, Brain, Sleep Disorder | Not applicable | Withdrawn | Children's Hospital Medical Center, Cincinnati | 2024-01-30 | 2024-02-09 | |
| Concussion Health Improvement Program Concussion-focused cognitive behavioral therapy, Parent skills training, Care management - Concussion, Brain, Brain Injury Traumatic Mild | Not applicable | Recruiting | Seattle Children's Hospital | 304 | 2023-11-10 | 2025-03-13 |
| Diffusion Tensor Brain MRI in the Detection of Structural Abnormality of the White Substance in Concussion specific MRI Acquisition (Diffusion Tensor Imaging) at 3T - Concussion, Brain | Not applicable | Completed | University Hospital, Clermont-Ferrand | 59 | 2023-10-22 | 2026-09-04 |
| Combined Neuromodulation and Cognitive Training for Post-mTBI Depression iTBS, sham iTBS, Personalized, Augmented Cognitive Training (PACT) - Depression, Mild Traumatic Brain Injury | Not applicable | Recruiting | University of California, San Diego | 72 | 2023-09-19 | 2026-05-01 |
| The Effects of Environmental Distractions on SCAT6 Outcomes SCAT6, Visual/ Auditory Distraction - Concussion, Brain, Mild Traumatic Brain Injury | Not applicable | Completed | Indiana University | 48 | 2023-09-01 | 2024-06-24 |
| Longitudinal Assessment of Post-concussion Driving in Young Adults Brain Injuries, Traumatic, Concussion, Brain | Enrolling by invitation | University of Georgia | 1000 | 2023-08-29 | 2023-12-13 |
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Brain Concussion (105) · Brain Injuries, Traumatic (27) · Post-Concussion Syndrome (8) · Brain Injuries (6) · Craniocerebral Trauma (6) · Athletic Injuries (5) · Depression (5) · Motor Activity (5) · Anxiety Disorders (4) · Cognitive Dysfunction (3) · Dementia (3) · Headache (3) · Wounds and Injuries (3) · Disease (2) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (2)
Brain Diseases (105) · Central Nervous System Diseases (105) · Nervous System Diseases (105) · Trauma, Nervous System (105) · Wounds, Nonpenetrating (105) · Head Injuries, Closed (104) · Wounds and Injuries (102) · Brain Injuries (99) · Craniocerebral Trauma (99) · Brain Injuries, Traumatic (78) · Pathological Conditions, Signs and Symptoms (14) · Behavior (12) · Mental Disorders (12) · Signs and Symptoms (8) · Neurologic Manifestations (7)
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BrainScope Company, Inc. (7) · Seattle Children's Hospital (6) · University of North Carolina, Chapel Hill (6) · University of Calgary (4) · California State University, Northridge (3) · Oculogica, Inc. (3) · Akiva Cohen (2) · Children's Hospital Medical Center, Cincinnati (2) · Children's National Research Institute (2) · Indiana University (2) · Johns Hopkins University (2) · Mayo Clinic (2) · State University of New York at Buffalo (2) · University Hospital, Clermont-Ferrand (2) · University of Texas Southwestern Medical Center (2)
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Leslie Prichep, Ph.D. (6) · Aimie Kachingwe, Dr. (2) · Daniel Corwin, MD (2) · Johna K Register-Mihalik, PhD (2) · Margaret Roller, Dr. (2) · Rosina Samadani, PhD (2) · Sara P Chrisman, MD MPH (2) · William Meehan, MD (2) · Aimie Kachingwe, Dr (1) · Alicia Trbovich, PhD (1) · Amy Romandine-Kratz, MD (1) · Anthony P Kontos, PhD (1) · Arnoley S Abcejo, MD (1) · Barry Willer, PhD (1)
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UL1TR001412 (2), R01HD090230 (1), R01HD094722 (1), R01HD108133 (1), R01NS129617 (1)