14 completed, 7 unknown, 5 recruiting, 4 terminated. 16 Not applicable, 4 Phase 3, 3 Phase 2, 2 Early Phase 1, 2 Phase 4.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| How the Brain and Body Recover After a Wrist Fracture Wrist Fracture, Complex Regional Pain Syndrome | Recruiting | Cambridge University Hospitals NHS Foundation Trust | 200 | 2026-08-12 | 2026-08-20 | |
| Hyperbaric Oxygen Therapy in Complex Regional Pain Syndrome Early hyperbaric oxygen therapy (HBOT), Delayed hyperbaric oxygen therapy (HBOT) - Chronic Pain, Complex Regional Pain Syndrome | Not applicable | Recruiting | University Hospital Ostrava | 60 | 2026-04-01 | 2026-08-25 |
| Complex Regional Pain Syndrome: Analgesic Outcome Chronic Pain, Complex Regional Pain Syndrome | Completed | Ciusss de L'Est de l'Île de Montréal | 201 | 2025-11-15 | 2026-10-08 | |
| The Effects of Whirlpool and Contrast Bath in Patients with Complex Regional Pain Syndrome After Distal Radius Fracture Whirlpool Bath, Contrast Bath - Distal Radius Fracture, Complex Regional Pain Syndrome Type I | Not applicable | Recruiting | Afyonkarahisar Health Sciences University | 40 | 2025-01-31 | 2025-01-30 |
| CSS-SR Validation Study Complex Regional Pain Syndrome (CRPS) Severity Score - Self Report - Complex Regional Pain Syndrome, Pain | Enrolling by invitation | Hospital for Special Surgery, New York | 100 | 2025-01-27 | 2026-02-13 | |
| Comparative Effects of Mirror Therapy and Standard Physiotherapy in Complex Regional Pain Syndrome Mirror Therapy, Routine Physical Therapy - Complex Regional Pain Syndrome | Not applicable | Completed | University of Lahore | 52 | 2024-11-24 | 2026-01-12 |
| The Effects and Mechanisms of a High CBD Cannabis Extract (BRC-002) for the Treatment of Pain and Health in Complex Regional Pain Syndrome BRC-002, BRC-002 Placebo - Complex Regional Pain Syndrome | Phase 1 | Recruiting | University of California, San Diego | 52 | 2024-06-01 | 2024-06-07 |
| Low Dose Naltrexone Therapy for Complex Regional Pain Syndrome Low dose naltrexone, Placebo sugar capsules - Complex Regional Pain Syndrome, Chronic Pain | Phase 4 | Enrolling by invitation | Hospital for Special Surgery, New York | 40 | 2024-01-02 | 2026-11-06 |
| Treatment of Complex Regional Pain Syndrome Repetitive transcranial magnetic stimulation, Sensorimotor training - Complex Regional Pain Syndrome | Not applicable | Unknown | McMaster University | 18 | 2023-01-01 | 2023-10-19 |
| Contrast Compression Therapy for Post-Stroke Complex Regional Pain Syndrome Conventional Rehabilitation, Contrast Compression Therapy - Stroke, Complex Regional Pain Syndrome | Not applicable | Completed | Meltem Gunes Akinci | 72 | 2021-11-01 | 2025-07-14 |
| Study of TAK-935 as an Adjunctive Therapy in Adult Participants With Complex Regional Pain Syndrome (CRPS) Soticlestat, Placebo - Complex Regional Pain Syndrome | Phase 2 | Completed | Millennium Pharmaceuticals, Inc. | 24 | 2019-07-23 | 2026-09-14 |
| Nitrous Oxide for the Treatment of Complex Regional Pain Syndrome Nitrous Oxide, Oxygen - Complex Regional Pain Syndrome | Phase 3 | Completed | The Cleveland Clinic | 44 | 2019-07-02 | 2024-02-09 |
| Comparison of Dorsal Column Stimulation to Dorsal Root Ganglion Stimulation for Complex Regional Pain Syndrome The Nuvectra Algovita Dorsal Column Spinal Cord Stimulator, The Axium Neurostimulator System - Complex Regional Pain Syndrome | Terminated | The Cleveland Clinic | 1 | 2019-01-08 | 2023-02-27 | |
| Comparison of Gait Parameters Between Floor and Sponge Surfaces and Special Shoes Soft surface, Floor, Kyboot shoes - Arthroscopic Knee Surgery, Lower Limb Fractures | Not applicable | Unknown | Hadassah Medical Organization | 40 | 2017-04-01 | 2017-02-14 |
| Safety of Intravenous Neridronic Acid in CRPS Neridronic acid - Complex Regional Pain Syndrome | Phase 3 | Completed | Grünenthal GmbH | 580 | 2016-12-20 | 2019-11-21 |
| Light Irradiation and Outcome for Neuropathic Pain Linearly Polarized Near-Infrared light Irradiation - Complex Regional Pain Syndrome | Not applicable | Unknown | Taipei Medical University Shuang Ho Hospital | 44 | 2016-10-01 | 2022-05-04 |
| "Efficacy of Botulinum Toxin Injection in Reducing Limb Pain in Patients With Complex Regional Pain Syndrome" Botox + Lidocaine, Lidocaine alone - Complex Regional Pain Syndrome | Early Phase 1 | Unknown | VA Connecticut Healthcare System | 20 | 2016-07-01 | 2018-08-06 |
| Comparison of the Efficacy of the Ultrasound With Fluoroscopy in Guidance of Lumbar Sympathetic Block 24G intravenous route for Lumbar Sympathetic Block (LSB):, 15-cm Chiba needle for Lumbar Sympathetic Block (LSB), Ultrasound for Lumbar Sympathetic Block (LSB) - Complex Regional Pain Syndrome, Postherpetic Neuralgia | Not applicable | Unknown | Seoul National University | 50 | 2016-04-01 | 2016-06-10 |
| IV Lidocaine Infusion for Neuropathic Pain Neuropathic Pain, Complex Regional Pain Syndrome | Withdrawn | Henry Ford Health System | 2016-04-01 | 2023-02-16 | ||
| [18F]FTC-146 PET/MRI in Healthy Volunteers and in CRPS and Sciatica [18F]-FTC-146 - Complex Regional Pain Syndrome, Sciatica | Early Phase 1 | Completed | Stanford University | 24 | 2016-02-09 | 2018-03-05 |
Showing 20 of 34. Sign in to see all of them.
Complex Regional Pain Syndromes (34) · Chronic Pain (9) · Pain (4) · Agnosia (3) · Neuralgia (3) · Wrist Fractures (3) · Carpal Tunnel Syndrome (2) · Causalgia (2) · Diabetic Neuropathies (2) · Neuralgia, Postherpetic (2) · Peripheral Nervous System Diseases (2) · Back Pain (1) · Edema (1) · Facial Pain (1) · Failed Back Surgery Syndrome (1)
Autonomic Nervous System Diseases (34) · Nervous System Diseases (34) · Neuromuscular Diseases (34) · Peripheral Nervous System Diseases (32) · Pathological Conditions, Signs and Symptoms (21) · Signs and Symptoms (21) · Neurologic Manifestations (20) · Pain (12) · Wounds and Injuries (6) · Neuralgia (4) · Neurobehavioral Manifestations (4) · Perceptual Disorders (4) · Arm Injuries (3) · Fractures, Bone (3) · Mononeuropathies (3)
Ketamine (2) · Levobupivacaine (2) · Lidocaine (2) · 6-(3-fluoropropyl)-3-(2-(azepan-1-yl)ethyl)benzo(d)thiazol-2(3H)-one (1) · 6-amino-1-hydroxyhexane-1,1-diphosphonate (1) · Botulinum Toxins, Type A (1) · Bupivacaine (1) · Control Groups (1) · Floors and Floorcoverings (1) · Gabapentin (1) · Hydrotherapy (1) · Injections, Epidural (1) · Lidoderm (1) · Mirror Movement Therapy (1) · Naltrexone (1)
Hospital for Special Surgery, New York (3) · Stanford University (2) · The Cleveland Clinic (2) · Afyonkarahisar Health Sciences University (1) · Axsome Therapeutics, Inc. (1) · Boston Scientific Corporation (1) · CHU de Quebec-Universite Laval (1) · Cambridge University Hospitals NHS Foundation Trust (1) · Ciusss de L'Est de l'Île de Montréal (1) · Drexel University College of Medicine (1) · Endo USA Inc., a Keenova Therapeutics Company (1) · Grünenthal GmbH (1) · Hadassah Medical Organization (1) · Hamilton Health Sciences Corporation (1) · Henry Ford Health System (1)
United States (17) · Canada (6) · United Kingdom (3) · Germany (2) · South Korea (2) · Turkey (Türkiye) (2) · Australia (1) · Czechia (1) · France (1) · Pakistan (1) · Taiwan (1)
Alexandra Sideris, PhD (2) · Daniel I Richman, MD (1) · Fadel Zeidan, PhD (1) · Jason Hale, MD (1) · Joy C MacDermid, PhD (1) · Marc Fischler (1) · Michael S Shuler, MD (1) · Michel Prud'Homme, MD, PhD (1) · Peter Konrad, M.D. (1) · Robert Bolash, MD (1) · Robert M Brownstone, MD, PhD (1) · Sandip Biswal, MD (1)
PMID 19465507, PMID 26324857, PMID 28340289, PMID 29189275, PMID 30671237, PMID 30908579, PMID 31858880, PMID 34592050, PMID 35005383, PMID 36538782, PMID 37306570, PMID 39239587, PMID 39318174, PMID 39335652, PMID 40118675, PMID 41261073
2016 (1)