17 completed, 5 recruiting, 3 active not recruiting, 2 terminated. 21 Not applicable, 1 Early Phase 1, 1 Phase 1, 1 Phase 3, 1 Phase 4.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluating Sucrose and Cold Oral Interventions for the Treatment of Oral Pruritus During Allergy Procedures. Food (sucrose), Food (popsicle), Food(Sucrose and cold) - Allergy, Food Allergies | Not applicable | Not yet recruiting | Philippe Bégin | 48 | 2026-11-01 | 2026-11-04 |
| Sex Differences in Cold-Induced Changes in Maximal Fat Oxidation Cold temperature, Room Temperature - Exercise | Not applicable | Recruiting | Colorado State University | 20 | 2026-04-15 | 2026-05-15 |
| Thermal Therapies in the Treatment of Muscle Injuries Cold water immersion, Hot water immersion, Physiotherapy only - Hamstring Injuries, Hamstring Muscle Repair | Not applicable | Recruiting | Aspetar | 135 | 2025-09-01 | 2026-10-28 |
| Cold Spray for Insulin-Injection Pain in the Emergency Department Cold (vapocoolant) spray, Placebo (sterile-water) spray - Pain, Diabetes Mellitus | Not applicable | Completed | Abant Izzet Baysal University | 100 | 2025-02-05 | 2026-07-27 |
| The Effects of Short-Chain Fatty Acids in Psychosocial Stress-Induced Impairment on Core Executive Functions Short Chain Fatty Acids (SCFAs)., Placebo, Maastricht Acute Stress Task - Executive Function | Not applicable | Completed | Universitaire Ziekenhuizen KU Leuven | 80 | 2024-11-13 | 2026-10-26 |
| Acute Effects of Cold Exposure on Cognitive Function Low temperature (15℃) group, Moderate temperature (22℃) group - Cognitive Function | Not applicable | Active not recruiting | Fudan University | 40 | 2024-10-16 | 2025-02-27 |
| Acute Effects of Cold Exposure on Cardiovascular System Low temperature (15°C) group, Moderate temperature (22°C) group - Cardiovascular System | Not applicable | Recruiting | Fudan University | 40 | 2024-10-16 | 2025-02-27 |
| Acute Effects of Low Temperature Exposure on Respiratory System Low temperature (15°C) group, Moderate temperature (22°C) group - Lung Function | Not applicable | Active not recruiting | Fudan University | 40 | 2024-10-16 | 2025-02-27 |
| Monitoring Intermittent Fasting for Human Optimization Using Wearable Technology: An N-of-1 Study Glucose-Ketone Index (GKI) monitoring, Continuous Glucose Monitoring (CGM), Digital dynamometer - Intermittent Fasting, Healthy | Not applicable | Completed | Institute for Digital Medicine (WisDM) | 1 | 2024-10-07 | 2025-07-04 |
| Single Effort in Air Temperature of Minus 10°C cold, neutral - Healthy | Not applicable | Completed | University School of Physical Education, Krakow, Poland | 30 | 2024-05-11 | 2026-06-23 |
| Sweat Rate Measurement With a Sensor (Wearable) in Different Climatic Conditions With Road Cyclists. Low intensity, Low temperature, Low Humidity - Sweat | Not applicable | Completed | Universidad Católica San Antonio de Murcia | 12 | 2024-02-19 | 2024-06-24 |
| Acute Health Effects of Low Temperature Exposure Low temperature (16#) group, Moderate temperature (22#) group - Cardiovascular System, Respiratory System | Not applicable | Active not recruiting | Fudan University | 50 | 2023-10-10 | 2026-09-02 |
| Mechanism of Human Cold Pain Perception - Involvement of TRPA1, TRPM8, Nav1.7 and Nav1.8 Room temperature, Cold temperature, Lidocain - Pain | Early Phase 1 | Completed | Medical University of Vienna | 36 | 2023-07-07 | 2024-03-15 |
| Early-Warning Intervention for Heat and Cold in Older Hypertensive Patients: Impact on Sleep Quality Issuing health risk warning for a heat or cold, A digital heat or cold health risk early warning tool, Perform daily self-monitoring of their BP and ECG - Hypertension | Not applicable | Completed | Tiantian Li | 378 | 2023-07-01 | 2024-10-30 |
| Total-body Glucose Utilization in Obesity Movies, Cold, Hyperinsulinemic euglycemic clamp - Obesity and Overweight | Phase 4 | Recruiting | Turku University Hospital | 60 | 2023-01-25 | 2024-12-18 |
| Symbiofilm Trial in Allergic Kids (SYMBIOFILM-TAK) Healsea® Children, Conventional therapies for common cold - Common Cold, Allergy | Completed | Lallemand Pharma AG | 186 | 2022-02-14 | 2025-01-20 | |
| Pharmacokinetics of Adrenaline After Administration of ARS -1 in Subjects With Upper Respiratory Tract Infection ARS-1 with URTI, ARS-1 without URTI - Upper Respiratory Tract Infection | Phase 1 | Completed | ARS Pharmaceuticals, Inc. | 15 | 2021-08-09 | 2022-07-29 |
| Predicting Severity and Disease Progression in Influenza-like Illness (Including COVID-19) Respiratory infections - Influenza, SARS (Severe Acute Respiratory Syndrome) | Terminated | Imperial College London | 8 | 2021-01-25 | 2024-05-17 | |
| Cold Milk for Dysphagia in Preterm Infants Standard room temperature (RTS) feeding of milk/formula, Cold temperature (CS, at 4-9°C) of milk/formula - Dysphagia of Newborn | Not applicable | Completed | NYU Langone Health | 22 | 2021-01-04 | 2025-04-10 |
| Establishing Normative Values for Thermal Detection and Pain Threshold Established by the Psi Method Thermal QST (CDT, WDT, CPT, HPT) with the method of limits, Thermal QST (cold and warm detection, heat pain) with the psi method, Neurological examination - Small Fiber Neuropathy | Not applicable | Suspended | Université Catholique de Louvain | 80 | 2020-10-10 | 2021-10-08 |
Showing 20 of 30. Sign in to see all of them.
Respiratory Tract Infections (4) · Common Cold (2) · Hypersensitivity (2) · Pain (2) · Asthma (1) · Bacterial Infections (1) · Body Temperature Changes (1) · COVID-19 (1) · Contraception Behavior (1) · Diabetes Mellitus (1) · Emergencies (1) · Environmental Illness (1) · Fever (1) · Food Hypersensitivity (1) · Hypertension (1)
Fudan University (4) · Universitaire Ziekenhuizen KU Leuven (2) · ARS Pharmaceuticals, Inc. (1) · Abant Izzet Baysal University (1) · Aspetar (1) · Colorado State University (1) · Imperial College London (1) · Institute for Digital Medicine (WisDM) (1) · Karolinska Institutet (1) · Lallemand Pharma AG (1) · Medical University of Vienna (1) · NYU Langone Health (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1) · Ospedale di Cavalese (1) · Philippe Bégin (1)
China (5) · United States (4) · Belgium (3) · Canada (2) · Poland (2) · Spain (2) · Australia (1) · Austria (1) · Chile (1) · Finland (1) · Indonesia (1) · Italy (1) · Japan (1) · Qatar (1) · Singapore (1)
Haidong Kan, PhD (4) · Akira Horiuchi, MD (1) · Anthony McGirr, MD (1) · Christopher Bell (1) · Christopher Chiu, PhD (1) · David Proud, PhD (1) · Dean Ho, PhD (1) · Denise Wilkes, MD-PhD (1) · Faruk Danis (1) · Lauri Nummenmaa, Professor (1) · Maria Cronhjort, MD, PhD (1)
PMID 16229972, PMID 18989788, PMID 21029354, PMID 21412369, PMID 22570562, PMID 22704854, PMID 23340535, PMID 25437498, PMID 26469365, PMID 26685018, PMID 27898461, PMID 27908840, PMID 27993558, PMID 28402092, PMID 30482135, PMID 31890195, PMID 35065046, PMID 38947097, PMID 39693244, PMID 40362766, PMID 40677618, PMID 8815179
R21HD100653 (1)