Picornaviridae Infections: Clinical Trials

510 completed, 70 unknown, 31 recruiting, 23 withdrawn. 188 Phase 3, 150 Not applicable, 128 Phase 4, 97 Phase 2, 53 Phase 1.

By phase and status

Phase	Trials	Status
Phase 3	188	Completed 153, Withdrawn 12, Unknown 9, Terminated 5, Recruiting 4, Active not recruiting 2, Not yet recruiting 2, Suspended 1
Not applicable	150	Completed 103, Unknown 18, Recruiting 11, Active not recruiting 6, Not yet recruiting 6, Withdrawn 3, Terminated 2, Enrolling by invitation 1
Phase 4	128	Completed 99, Unknown 17, Withdrawn 4, Not yet recruiting 3, Recruiting 2, Terminated 2, Active not recruiting 1
Phase 2	97	Completed 73, Recruiting 6, Terminated 6, Unknown 6, Withdrawn 3, Active not recruiting 2, Not yet recruiting 1
Phase 1	53	Completed 42, Unknown 5, Recruiting 3, Active not recruiting 1, Not yet recruiting 1, Terminated 1
Early Phase 1	1	Completed 1

Follow Picornaviridae Infections: new trials by email Literature Review of Picornaviridae Infections trials Research Report on Picornaviridae Infections

Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
Natural History of Trisomy 8-Associated Autoinflammatory Disease (TRIAD) and Related Disorders Trisomy 8 Mosaicism, Trisomy 8 Associated Autoinflammatory Disease		Recruiting	National Institute of Allergy and Infectious Diseases (NIAID)	750	2026-11-05	2026-11-02
Post-market Clinical Follow-up Study of an Isotonic Saline Solution for the Relief of Nasal Congestion in Infants and Toddlers Quinton Medical Nasal Health Baby® - Nasal Congestion, Common Cold		Not yet recruiting	Laboratoires Quinton International S.L.	83	2026-11-01	2026-10-13
Enhanced Telemedicine in Primary Care for Acute Respiratory Tract Infections Study Tele-Otoscope Enabled Primary Care, eBook-supported primary care - Acute Respiratory Tract Infection, Ear Infection	Not applicable	Not yet recruiting	University of Pittsburgh	450	2026-11-01	2026-10-27
Observational Study of RHINOSEDAL in Acute Nasal Obstruction RHINOSEDAL - Nasal Obstruction, Common Cold		Not yet recruiting	Laboratoires Elerte	126	2026-10-15	2026-06-02
Observational Study of SIROPSEDAL in Acute Cough Acute Cough, Upper Respiratory Tract Infection		Not yet recruiting	Laboratoires Elerte	124	2026-10-15	2026-06-04
A Phase I/II Clinical Trial of the Diphtheria, Tetanus, Acellular Component Pertussis and Sabin Inactivated Poliomyelitis Vaccine Adsorbed Diphtheria, Tetanus, Acellular Component Pertussis and Sabin Inactivated Poliomyelitis Vaccine Adsorbed, Diphtheria, Tetanus and Acellular Component Pertussis Combined Vaccine, Diphtheria, Tetanus and Acellular Component Pertussis Combined Vaccine+Inactivated Poliomyelitis Vaccine Made From Sabin Strains - Diphtheria, Pertussis	Phase 1 / Phase 2	Recruiting	Institute of Medical Biology, Chinese Academy of Medical Sciences	380	2026-10-11	2026-10-23
Effect of Immune X on Common Cold Incidence in Healthy Adults Immune X, Placebo - Common Cold, Upper Respiratory Tract Infection (URTI)	Not applicable	Recruiting	Givaudan France Naturals	160	2026-10-09	2026-10-13
CHIPCAT and HFMD-PREP for HFMD Prevention in Childcare Centres in Kota Kinabalu HFMD-PREP (HFMD Prevention and Response Enhancement Programme) - Hand, Foot and Mouth Disease, Infection Control	Not applicable	Not yet recruiting	Helmy Sajali, MD, MPH	780	2026-10-01	2026-10-13
Study of BK1803 in Healthy Infants BK1803, GOBIK Aqueous Suspension Syringes, Bimmugen® Injection - Pertussis, Diphtheria	Phase 3	Not yet recruiting	Tanabe Pharma Corporation	344	2026-10-01	2026-08-28
Probiotic Trial for URTI Prevention in Healthy Adults Probiotic Formula, Matching placebo - Upper Respiratory Tract Infections	Not applicable	Recruiting	Harokopio University	140	2026-10-01	2026-11-02
Risk Factors and Outcomes of Hepatitis A in Children Hepatitis A, Acute Hepatitis		Not yet recruiting	Assiut University	190	2026-09-26	2026-09-30
Bridging Clinical Trial of EV71 Vaccine in Vietnamese Children EV71 vaccine - Hand, Foot, and Mouth Disease (HFMD), Enterovirus 71 Infection	Not applicable	Not yet recruiting	Sinovac Biotech Co., Ltd	320	2026-09-19	2026-09-01
Safety and Immunogenicity of a Recombinant Poliomyelitis Vaccine (rPV) in Comparison With IPOL Vaccine in Healthy Adults Recombinant Poliomyelitis Vaccine (rPV), Inactivated Poliomyelitis Vaccine (IPOL) - Polio Immunity	Phase 1	Recruiting	Serum Institute of India Pvt. Ltd.	36	2026-09-11	2026-09-29
The Effect of the Cold Arm Sling Elevation Pillow on Postoperative Anxiety and Comfort in Children Cold and arm sling elevation pillow, Standard postoperative care - Upper Extremity Fractures, Postoperative Anxiety	Not applicable	Not yet recruiting	Istanbul University - Cerrahpasa	80	2026-09-01	2026-07-07
Study on the Long-Term Persistence of Immunity Induced by Inactivated Hepatitis A Vaccine Healive®, Havrix® - Hepatitis A		Recruiting	Sinovac Biotech Co., Ltd	106	2026-08-02	2026-10-22
Evaluation of Topical Rebamipide Versus Topical Betamethasone for Treatment of Oral Aphthous Ulcers Rebamipide mouthwash, Betamethasone mouthwash - Oral Aphthous Ulcers	Phase 2	Recruiting	Cairo University	46	2026-07-01	2026-10-06
A Novel Cold and Flu Herbal Blend for Reducing the Duration and Severity of the Common Cold Novel Herbal Cold & Flu Blend, Placebo - URTI, Common Cold	Phase 2	Not yet recruiting	RDC Clinical Pty Ltd	300	2026-07-01	2026-06-11
Fixed-dose Combination of 1000 mg Dipyrone Monohydrate + 60 mg Caffeine + 4 mg Chlorpheniramine Maleate in Improving Symptoms of the Common Cold and Flu in Adults dipyrone monohydrate 1000 mg + chlorpheniramine maleate 4 mg + caffeine 60 mg, dipyrone monohydrate 500 mg + chlorpheniramine maleate 2 mg + caffeine 30 mg, Placebo - Common Cold/Flu, Nasal Congestion	Phase 3	Recruiting	Brainfarma Industria Química e Farmacêutica S/A	620	2026-05-08	2026-06-16
Protective Efficacy , Immunogenicity and Safety of the Tetravalent Inactivated Enterovirus Vaccine (Vero Cell). Tetravalent Inactivated Enterovirus Vaccine (Vero Cell), Placebo - Hand, Foot, and Mouth Disease(HFMD), Herpangina	Phase 3	Not yet recruiting	Sinovac Biotech Co., Ltd	6000	2026-05-01	2026-05-28
A Study to Evaluate the Mucosal Intestinal Immunity to Poliovirus Type-2 of nOPV2 at Birth Dose in Healthy IPV Vaccinated Infants nOPV2 - Poliomyelitis	Phase 3	Recruiting	Fidec Corporation	740	2026-04-30	2026-09-09

Showing 20 of 686. Sign in to see all of them.

Narrower conditions

Poliomyelitis (263)  ·  Common Cold (218)  ·  Tetanus (115)  ·  Diphtheria (114)  ·  Hepatitis B (90)  ·  Whooping Cough (85)  ·  Hepatitis A (82)  ·  Haemophilus Infections (71)  ·  Hand, Foot and Mouth Disease (59)  ·  Influenza, Human (53)  ·  Enterovirus Infections (47)  ·  Respiratory Tract Infections (38)  ·  Postpoliomyelitis Syndrome (28)  ·  Virus Diseases (20)  ·  Hepatitis (18)

Broader conditions

Infections (678)  ·  RNA Virus Infections (678)  ·  Virus Diseases (666)  ·  Enterovirus Infections (418)  ·  Respiratory Tract Diseases (313)  ·  Nervous System Diseases (297)  ·  Neuroinflammatory Diseases (295)  ·  Central Nervous System Diseases (293)  ·  Central Nervous System Infections (291)  ·  Myelitis (284)  ·  Spinal Cord Diseases (283)  ·  Neuromuscular Diseases (282)  ·  Respiratory Tract Infections (273)  ·  Digestive System Diseases (156)

Interventions

Hepatitis A Vaccines (29)  ·  Poliovirus Vaccine, Inactivated (28)  ·  diphtheria-tetanus-acellular pertussis-inactivated poliovirus-Haemophilus influenzae b conjugate-hepatitis B vaccine (27)  ·  Acetaminophen (14)  ·  Tetanus Toxoid (14)  ·  Diphtheria-Tetanus-acellular Pertussis Vaccines (12)  ·  Pentavac (11)  ·  DTaP-IPV-HB-PRP-T vaccine (10)  ·  Blood Specimen Collection (9)  ·  Hepatitis B Vaccines (9)  ·  Heptavalent Pneumococcal Conjugate Vaccine (9)  ·  Engerix-B (8)  ·  pentacel (8)  ·  twinrix (8)  ·  13-valent pneumococcal vaccine (7)

Sponsors

GlaxoSmithKline (80)  ·  Sanofi Pasteur, a Sanofi Company (48)  ·  Sinovac Biotech Co., Ltd (46)  ·  Centers for Disease Control and Prevention (17)  ·  Institute of Medical Biology, Chinese Academy of Medical Sciences (16)  ·  Sanofi (15)  ·  Aga Khan University (12)  ·  Jiangsu Province Centers for Disease Control and Prevention (12)  ·  Fidec Corporation (10)  ·  Valenta Pharm JSC (9)  ·  LG Chem (8)  ·  PATH (8)  ·  Gilead Sciences (7)  ·  Merck Sharp & Dohme LLC (7)  ·  Ache Laboratorios Farmaceuticos S.A. (6)

Countries

China (119)  ·  United States (94)  ·  France (28)  ·  Germany (28)  ·  United Kingdom (25)  ·  Bangladesh (22)  ·  Belgium (22)  ·  Canada (19)  ·  Italy (19)  ·  Russia (17)  ·  South Korea (17)  ·  Turkey (Türkiye) (16)  ·  Brazil (14)  ·  Poland (14)  ·  Thailand (14)

Top investigators

Ekaterina Zakharova, MD, PhD (5)  ·  Yuemei Hu (5)  ·  Zhaojun Mo, Master (5)  ·  Fengcai Zhu, Master (4)  ·  Ingrid Kromann (4)  ·  Bobbi Langkamp-Henken, PhD, RD (3)  ·  Natchaya Kunanitthaworn, MD (3)  ·  Tavitiya Sudjaritruk, MD, PhD (3)  ·  Yan-pin Li, MD (3)  ·  Abhijeet Anand, MBBS, MPH (2)

Results publications

PMID 32710245, PMID 26873055, PMID 27553375, PMID 32867698, PMID 21366801, PMID 22153001, PMID 22426327, PMID 23372725, PMID 24260259, PMID 24261438, PMID 24508042, PMID 26190091, PMID 28340322, PMID 32273184, PMID 33487470, PMID 38218668, PMID 39088987, PMID 40318674, PMID 10025486, PMID 10511934, PMID 10719291, PMID 11855555, PMID 12517470, PMID 12719068, PMID 15117622, PMID 15288679, PMID 15293621, PMID 15379582, PMID 15561835, PMID 15817806, PMID 16049208, PMID 16061320, PMID 16218509, PMID 16708058, PMID 16713921, PMID 17090650, PMID 17152004, PMID 17259872, PMID 17264159, PMID 17429085, PMID 17474541, PMID 17531694, PMID 17947390, PMID 17980513, PMID 17990291, PMID 18226798, PMID 18233994, PMID 18676527, PMID 18816600, PMID 19117896

NIH funding

2014 (4), 2009 (2), 2015 (2), 2018 (2), 1RC1LM010424-01 (1), 2005 (1), 2008 (1), 2017 (1), 2019 (1), 5UM1AI148684-04 (1), R01AI130398 (1), R01AI201390 (1), R01AT001428 (1), R01AT006970 (1), R01DA017476 (1)