11 completed, 2 terminated, 1 unknown, 1 withdrawn. 7 Phase 4, 5 Phase 3, 2 Not applicable, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 7 | Completed 3, Terminated 2, Unknown 1, Withdrawn 1 |
| Phase 3 | 5 | Completed 5 |
| Not applicable | 2 | Completed 2 |
| Phase 2 | 1 | Completed 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Eschscholzia Study Eschscholzia tablets, Placebo Tablets - Sleep | Phase 3 | Completed | A. Vogel AG | 104 | 2025-04-07 | 2026-04-06 |
| Sleep Well Observation Study Sleep Well Sachet - Sleep Disturbance | Not applicable | Completed | A. Vogel AG | 50 | 2023-03-14 | 2024-08-06 |
| Mental Balance Study Re-Focus "Verum" Tablets, Re-Focus "Placebo" Tablets - Mental Health Wellness 1, Work Related Stress | Not applicable | Completed | A. Vogel AG | 36 | 2023-03-09 | 2026-03-02 |
| Echinaforce COVID-19 Shedding Study Echinaforce Forte tablets, Echinaforce Chewable tablets, Echinaforce tincture - COVID-19 Respiratory Infection, SARS-CoV2 Infection | Phase 4 | Terminated | A. Vogel AG | 40 | 2021-11-15 | 2024-08-06 |
| Echinaforce Study to Investigate Explorative Pharmacology and Effectiveness to Prevent From Enveloped Virus Infections Echinaforce Chewable tablets - Respiratory Tract Infections, Common Cold | Phase 4 | Completed | A. Vogel AG | 122 | 2020-11-20 | 2021-08-12 |
| Safety and Efficacy of the Sore Throat Lozenges to Treat Acute Sore Throats A. Vogels Sore Throat lozenges - Tonsillopharyngitis, Respiratory Tract Infection Viral | Phase 4 | Completed | A. Vogel AG | 74 | 2019-03-12 | 2021-08-05 |
| Superiority of Newly Developed Over Basic Echinacea Formulations for the Treatment of Respiratory Tract Infections Echinacea purpurea alcoholic extract - Respiratory Tract Infections | Phase 2 / Phase 3 | Completed | A. Vogel AG | 246 | 2018-11-27 | 2021-05-04 |
| Study to Assess Safety and Efficacy of Nephrosolid Tbs to Stimulate Urinary Output in Non-patient Volunteers Nephrosolid tablets - Urine Specimen Collection | Phase 3 | Completed | A. Vogel AG | 66 | 2018-02-12 | 2020-04-08 |
| Echinaforce Junior Bioavailability Trial Echinaforce junior - Common Cold | Phase 4 | Withdrawn | A. Vogel AG | 2017-02-20 | 2018-07-18 | |
| Echinacea Junior vs Vitamin C in Children 4-12 Years Old Echinaforce - Respiratory Tract Infection Viral | Phase 3 | Completed | A. Vogel AG | 203 | 2016-11-25 | 2021-05-04 |
| Study of Echinaforce Junior Tablets in Children With Acute Colds Respiratory Tract Diseases | Completed | A. Vogel AG | 79 | 2014-10-15 | 2021-05-04 | |
| Efficacy and Safety of Sage Tablets Compared to Placebo in Menopausal Patients With Hot Flushes and Sweating Sage extract, 3400 mg , DER 1:17 - Menopausal Hot Flushes | Phase 4 | Terminated | A. Vogel AG | 107 | 2013-12-01 | 2015-07-21 |
| Clinical Study to Assess the Influence of a Saw Palmetto Preparation in Patients With Benign Prostatic Hyperplasia (BPH) and Sexual Dysfunctions Saw palmetto berry extract - Sexual Dysfunctions in Men With Benign Prostatic Hyperplasia | Phase 4 | Unknown | A. Vogel AG | 50 | 2009-11-01 | 2009-11-26 |
| Echinacea Safety Study echinacea, placebo - Infections | Phase 4 | Completed | A. Vogel AG | 757 | 2009-10-01 | 2014-07-23 |
| Clinical Trial for Assessment of Safety and Efficacy of a Echinacea/Sage Spray Compared to a Chlorhexidine/Lidocaine Spray in the Treatment of Acute Sore Throats chlorhexidine/lidocaine, echinacea/sage - Pharyngitis | Phase 3 | Completed | A. Vogel AG | 154 | 2006-02-01 | 2008-07-01 |
Common Cold (2) · Respiratory Tract Infections (2) · COVID-19 (1) · Hot Flashes (1) · Infections (1) · Occupational Stress (1) · Parasomnias (1) · Pharyngitis (1) · Prostatic Hyperplasia (1) · Respiratory Tract Diseases (1)
Echinacea extract (3) · Echinaforce (2) · Prostasan (1) · calcium D-pantothenate, L-cysteine drug combination (1) · chlorhexidine gluconate, lidocaine drug combination (1) · saw palmetto extract (1)
Switzerland (8) · Bulgaria (4) · United Kingdom (2) · Germany (1)
Alexandar Buchkov, Dr. med. (1) · Arnold Baechler, Dr. med. (1) · Bernhard Waelti, Dr. med. (1) · Emil Kolev, Dr. med. (1) · Eugen Riedi, MD (1) · Juliane Hellhammer, Dr (1) · Mercedes Ogal, Dr. med. (1)
PMID 14526713, PMID 15556647, PMID 16504956, PMID 17597571, PMID 19748859, PMID 33832544, PMID 37138742, PMID 41194549