Orthomyxoviridae Infections: Clinical Trials

1725 completed, 147 unknown, 99 recruiting, 77 terminated. 503 Phase 2, 431 Phase 3, 415 Phase 1, 346 Phase 4, 329 Not applicable.

By phase and status

Phase	Trials	Status
Phase 2	503	Completed 423, Withdrawn 20, Terminated 19, Recruiting 15, Unknown 15, Not yet recruiting 6, Active not recruiting 5
Phase 3	431	Completed 356, Recruiting 20, Unknown 18, Terminated 13, Withdrawn 10, Not yet recruiting 7, Suspended 4, Active not recruiting 3
Phase 1	415	Completed 352, Recruiting 17, Unknown 13, Withdrawn 13, Terminated 9, Active not recruiting 6, Not yet recruiting 4, Enrolling by invitation 1
Phase 4	346	Completed 266, Unknown 30, Terminated 15, Active not recruiting 13, Not yet recruiting 8, Recruiting 8, Withdrawn 4, Enrolling by invitation 1, Suspended 1
Not applicable	329	Completed 234, Unknown 30, Recruiting 19, Not yet recruiting 13, Terminated 13, Active not recruiting 9, Withdrawn 6, Enrolling by invitation 5
Early Phase 1	7	Completed 5, Active not recruiting 1, Not yet recruiting 1

Follow Orthomyxoviridae Infections: new trials by email Literature Review of Orthomyxoviridae Infections trials Research Report on Orthomyxoviridae Infections

Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
How Healthy Adults Respond to the Nasal Flu Vaccine FluMist (Live Attenuated Influenza Vaccine) - Mucosal Immune Response to Influenza Vaccination	Phase 4	Not yet recruiting	University of Alabama at Birmingham	20	2026-12-01	2026-10-13
A Human Influenza Transmission Study Using Naturally Infected Community Donors Influenza Donor Visit, Influenza Recipient Inpatient Exposures Sessions - Influenza	Not applicable	Not yet recruiting	Emory University	150	2026-12-01	2026-09-11
Evaluating AVM0703 for Treatment of COVID-19 or Influenza-mediated ARDS AVM0703, Placebo - ARDS, Covid19	Phase 1	Not yet recruiting	AVM Biotechnology Inc	16	2026-12-01	2025-10-02
A Trial of RLX-2508-102 in Healthy Volunteers RLX-2508 - Influenza	Early Phase 1	Not yet recruiting	Atridia Pty Ltd.	101	2026-11-15	2026-10-14
Study of a Combination SARS-CoV-2 Recombinant Spike and High-Dose Inactivated Influenza Vaccine With Matrix-M Adjuvant in Adult Participants 60 Years of Age and Older IIV-HD (standalone), NVXC19 (EU licensed, standalone), IIV-HD + NVXC19 combination - Immunization, Healthy Volunteers	Phase 3	Not yet recruiting	Sanofi	6000	2026-11-09	2026-10-22
Preoperative Pneumococcal and Influenza Vaccination to Prevent Postoperative Pulmonary Infection in Patients Undergoing Lung Resection for Pulmonary Nodules or Lung Cancer 23-valent pneumococcal polysaccharide vaccine, Quadrivalent split-virion influenza vaccine - Pneumococcal Polysaccharide Vaccine, Influenza Vaccines	Phase 4	Not yet recruiting	The First Affiliated Hospital of Guangzhou Medical University	1278	2026-11-01	2026-10-21
Immunogenicity of Standard-Dose Versus High-Dose Influenza Vaccines in Older Adults in Singapore High-dose influenza vaccine, Standard-dose influenza vaccine - Influenza	Phase 4	Not yet recruiting	Tan Tock Seng Hospital	150	2026-11-01	2026-10-20
Assessment of the Acceptability of, and Factors Associated With, Recommended Vaccinations During Pregnancy in Maternity Units in the Ile-de-France Region Vaccination Coverage Among Pregnant Women		Not yet recruiting	Assistance Publique - Hôpitaux de Paris	1605	2026-11-01	2026-10-20
BPL-1357 Against H1N1 Influenza Virus Challenge BPL-1357 IM, BPL-1357 IN, Placebo IM - Influenza, Human	Phase 2	Recruiting	National Institute of Allergy and Infectious Diseases (NIAID)	129	2026-10-27	2026-10-22
A Study to Confirm Efficacy of a Single Dose of Baloxavir Marboxil in the Post-exposure Prophylaxis (PEP) of Influenza Virus Infection in Chinese Participants Baloxavir marboxil, Placebo - Influenza, Human, Respiratory Tract Infections	Phase 3	Recruiting	Hoffmann-La Roche	325	2026-10-16	2026-10-22
SAFE (Self-Administration of Flumist to ImprovE Uptake: A Household-Based Cluster Randomized Trial) LAIV FLUMIST - Influenza (Healthy Volunteers)	Phase 4	Not yet recruiting	McMaster University	966	2026-10-15	2026-07-31
Sequential Digital Intervention to Increase Influenza Vaccination in Patients With Heart Failure Routine Influenza Vaccination Recommendation, Repeated AI-Assisted Telephone Intervention, Gain-Framed SMS Reminder - Heart Failure, Influenza Vaccination	Not applicable	Not yet recruiting	Heart Health Research Center	588	2026-10-15	2026-10-19
A Study of Updated mRNA Seasonal Influenza Vaccines mRNA-1010, Licensed High-Dose Seasonal Influenza Vaccine - Seasonal Influenza	Phase 4	Not yet recruiting	ModernaTX, Inc.	200	2026-10-15	2026-10-20
A Study of SYH2085 Tablets Compared With Placebo in Chinese Adult Patients With Uncomplicated Influenza. SYH2085, Placebo - Influenza	Phase 2	Not yet recruiting	CSPC ZhongQi Pharmaceutical Technology Co., Ltd.	213	2026-10-10	2026-09-01
A Study to Evaluate the Immune Responses of Subunit Influenza Vaccine in Healthy Adults Group A, Group B - Influenza	Phase 4	Active not recruiting	Ab&B Bio-tech Co., Ltd.JS	138	2026-10-10	2026-10-16
Family Physician Nudges for Influenza Vaccination Among Older Adults Family Physician Influenza Vaccination Nudge - Influenza Vaccination	Not applicable	Not yet recruiting	Fudan University	5250	2026-10-08	2026-10-08
A Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1010 in Healthy Children mRNA-1010, Fluarix Trivalent - Seasonal Influenza	Phase 1	Not yet recruiting	ModernaTX, Inc.	96	2026-10-07	2026-10-13
Artificial Intelligence-assisted Primary Care for Influenza Vaccination Among Chronic Patients in China (AIPC-Flu) AI-assisted primary care intervention - Influenza Vaccination	Not applicable	Not yet recruiting	Fudan University	1300	2026-10-06	2026-10-14
A Study to Evaluate the Immune Response and Safety of a Vaccine Against Influenza in Adults 18-64 Years of Age mRNA Seasonal Flu vaccine, Comparator 1, Comparator 2 - Influenza, Human	Phase 3	Recruiting	GlaxoSmithKline	3000	2026-10-01	2026-10-09
Abbott ID NOW Point-of-Care Testing Abbott ID NOW Point-of-Care Testing, Standard Laboratory-Based RT-PCR Diagnostic Pathway - Influenza, Influenza-like Illness	Not applicable	Recruiting	China Medical University Hospital	1080	2026-10-01	2026-09-29

Showing 20 of 2206. Sign in to see all of them.

Narrower conditions

Influenza, Human (2157)  ·  COVID-19 (117)  ·  Virus Diseases (100)  ·  Influenza in Birds (96)  ·  Respiratory Tract Infections (88)  ·  Infections (53)  ·  Common Cold (47)  ·  Pneumonia (34)  ·  Respiratory Tract Diseases (26)  ·  Coronavirus Infections (20)  ·  RNA Virus Infections (20)  ·  Respiratory Syncytial Virus Infections (17)  ·  HIV Infections (16)  ·  Whooping Cough (16)

Broader conditions

RNA Virus Infections (2186)  ·  Infections (2153)  ·  Respiratory Tract Diseases (2137)  ·  Virus Diseases (2106)  ·  Respiratory Tract Infections (2074)  ·  Lung Diseases (175)  ·  Coronaviridae Infections (130)  ·  Nidovirales Infections (130)  ·  Pneumonia (126)  ·  Pathological Conditions, Signs and Symptoms (123)  ·  Pneumonia, Viral (116)  ·  Coronavirus Infections (110)  ·  Animal Diseases (96)  ·  Bird Diseases (96)

Interventions

Influenza Vaccines (425)  ·  Oseltamivir (87)  ·  FluMist (60)  ·  fluarix (52)  ·  vaxigrip (47)  ·  Vaccines (34)  ·  Sodium Chloride (33)  ·  baloxavir (22)  ·  fluad vaccine (21)  ·  Fluzone High-Dose (16)  ·  Saline Solution (16)  ·  FluBlok (15)  ·  Adjuvants, Pharmaceutic (14)  ·  Zanamivir (14)  ·  mRNA-1010 influenza vaccine (13)

Sponsors

GlaxoSmithKline (184)  ·  National Institute of Allergy and Infectious Diseases (NIAID) (180)  ·  Sanofi Pasteur, a Sanofi Company (117)  ·  Novartis Vaccines (61)  ·  Seqirus (51)  ·  MedImmune LLC (41)  ·  Stanford University (29)  ·  Alachua Government Services, Inc. (26)  ·  Novartis (24)  ·  ModernaTX, Inc. (22)  ·  Sanofi (22)  ·  Hoffmann-La Roche (20)  ·  Crucell Holland BV (18)  ·  The University of Hong Kong (18)  ·  Sinovac Biotech Co., Ltd (17)

Countries

United States (926)  ·  Canada (149)  ·  United Kingdom (138)  ·  China (135)  ·  Germany (108)  ·  France (96)  ·  Belgium (93)  ·  Australia (86)  ·  Russia (63)  ·  Spain (60)  ·  South Korea (54)  ·  Poland (49)  ·  Italy (48)  ·  Thailand (47)  ·  Taiwan (46)

Top investigators

Robert Walker, MD (16)  ·  Cornelia Dekker, MD (14)  ·  Matthew J Memoli, M.D. (10)  ·  Melissa Stockwell, MD MPH (8)  ·  Nadine Rouphael, MD (8)  ·  Stephen Quake, PhD (8)

Results publications

PMID 28963118, PMID 33215698, PMID 36715243, PMID 39756216, PMID 19261173, PMID 21857263, PMID 26432909, PMID 26787832, PMID 28325769, PMID 29443825, PMID 29465480, PMID 29706550, PMID 30066805, PMID 32379201, PMID 32526188, PMID 34174187, PMID 39550717, PMID 42834081, PMID 18420314, PMID 18599164, PMID 19540952, PMID 19588665, PMID 19887665, PMID 20018364, PMID 20018365, PMID 20160606, PMID 21352939, PMID 21378375, PMID 21435708, PMID 21615847, PMID 21906647, PMID 21975270, PMID 22172502, PMID 22418809, PMID 22537984, PMID 22542645, PMID 22872731, PMID 22885014, PMID 22906937, PMID 24041010, PMID 24606983, PMID 24693893, PMID 25004134, PMID 25148380, PMID 25184864, PMID 25222307, PMID 26042486, PMID 26069949, PMID 26176592, PMID 26275339

NIH funding

2009 (23), U19AI057229 (20), 2008 (12), 2015 (10), 2016 (8), 2018 (7), R01AI135029 (7), 2023 (6), 2014 (5), P30AG034532 (5), 2025 (4), U19AI090019 (4), 2017 (3), 2019 (3), N01AI30025 (3)