14 completed, 1 recruiting, 1 terminated, 1 withdrawn. 7 Not applicable, 4 Phase 4, 3 Phase 2, 3 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 7 | Completed 6, Withdrawn 1 |
| Phase 4 | 4 | Completed 4 |
| Phase 2 | 3 | Completed 1, Recruiting 1, Terminated 1 |
| Phase 3 | 3 | Completed 3 |
Follow Echinacea extract: new trials by email Literature Review of Echinacea extract trials Research Report on Echinacea extract
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Effect of Echinacea (Immulant ®) in the Treatment of CRYPTOSPORIDIOSIS in Immunocompromised Children Echinacea Extract - Cryptosporidium Infection | Phase 2 | Recruiting | Al-Azhar University | 60 | 2026-01-18 | 2026-02-05 |
| Parasitic Infections and Ulcerative Colitis: Combining Anti-parasitic and Immunomodulatory Treatments May Achieve Remission Echinacea Extract, MetroNIDAZOLE 500 MG Oral Tablet [Flagyl] - Ulcerative Colitis | Not applicable | Completed | Benha University | 120 | 2023-09-12 | 2024-09-04 |
| Immune Diversity Response to Oral Dosing of Nutritional Health Products in Healthy Participants N-Acetyl-L-cysteine (NAC), Echinacea purpurea, Curcumin - Immunity Disorders | Not applicable | Completed | Immunoflex Therapeutics Inc. | 32 | 2021-01-10 | 2022-02-16 |
| Echinaforce Study to Investigate Explorative Pharmacology and Effectiveness to Prevent From Enveloped Virus Infections Echinaforce Chewable tablets - Respiratory Tract Infections, Common Cold | Phase 4 | Completed | A. Vogel AG | 122 | 2020-11-20 | 2021-08-12 |
| Echinacea Angustifolia (AnxioCalm) in Anxiety Echinacea angustifolia, Placebo - Generalized Anxiety Disorder | Phase 2 | Terminated | EuroPharma, Inc. | 100 | 2018-06-06 | 2022-03-24 |
| Echinacea Junior vs Vitamin C in Children 4-12 Years Old Echinaforce - Respiratory Tract Infection Viral | Phase 3 | Completed | A. Vogel AG | 203 | 2016-11-25 | 2021-05-04 |
| Drug Interactions Between Echinacea Purpurea and Etravirine Echinacea purpurea - HIV | Not applicable | Completed | Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia | 15 | 2011-04-01 | 2019-11-14 |
| Impact of Echinacea as Prophilaxis for Upper Respiratory Tract Infections in Children 1-5 Years Echinacea, Placebo - Upper Respiratory Tract Infections | Not applicable | Completed | Hormozgan University of Medical Sciences | 100 | 2010-05-01 | 2011-07-22 |
| Drug Interactions Between Echinacea Purpurea and Darunavir/Ritonavir Echinacea - HIV Infections | Phase 4 | Completed | Germans Trias i Pujol Hospital | 15 | 2010-01-01 | 2019-12-04 |
| Echinacea Safety Study echinacea, placebo - Infections | Phase 4 | Completed | A. Vogel AG | 757 | 2009-10-01 | 2014-07-23 |
| Immunologic Effects of Echinacea Echinacea purpurea, placebo - Upper Respiratory Tract Infections | Not applicable | Completed | University of Washington | 20 | 2009-03-01 | 2018-05-01 |
| Effects of Echinacea in Children Echinacea purpurea 100 mg/ml in liquid formulation, placebo - Upper Respiratory Infections | Not applicable | Withdrawn | University of Washington | 2008-11-01 | 2015-12-02 | |
| Drug Interactions of Echinacea, Ginseng, and Ginkgo Biloba Taken With Lopinavir/Ritonavir in Healthy Volunteers Gingko Biloba, Echinacea purpurea, Panax ginseng - Healthy | Phase 4 | Completed | National Institutes of Health Clinical Center (CC) | 47 | 2005-01-01 | 2012-04-16 |
| Echinacea Versus Placebo Effect in Common Cold (Physician Echinacea Placebo) Echinacea, Blinded placebo - Common Cold | Phase 3 | Completed | University of Wisconsin, Madison | 719 | 2003-09-01 | 2014-12-04 |
| Evaluation of Echinacea for the Common Cold Echinacea - Common Cold | Phase 2 | Completed | National Center for Complementary and Integrative Health (NCCIH) | 2001-09-01 | 2006-08-18 | |
| A Trial of Echinacea in Children Echinacea - Common Cold | Phase 3 | Completed | National Center for Complementary and Integrative Health (NCCIH) | 600 | 2000-04-01 | 2006-08-18 |
| Echinacea Purpurea and Osteopathy in Children With Recurrent Otitis Media Cranial osteopathic manipulative treatment., Echinacea purpurea, Sham osteopathic manipulative treatment - Otitis Media | Not applicable | Completed | University of Arizona | 90 | 1999-07-01 | 2008-06-03 |
Common Cold (4) · Respiratory Tract Infections (4) · Colitis, Ulcerative (1) · Cryptosporidiosis (1) · Generalized Anxiety Disorder (1) · HIV Infections (1) · Immune System Diseases (1) · Infections (1) · Otitis Media (1) · Virus Diseases (1)
A. Vogel AG (3) · National Center for Complementary and Integrative Health (NCCIH) (2) · University of Washington (2) · Al-Azhar University (1) · Benha University (1) · EuroPharma, Inc. (1) · Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia (1) · Germans Trias i Pujol Hospital (1) · Hormozgan University of Medical Sciences (1) · Immunoflex Therapeutics Inc. (1) · National Institutes of Health Clinical Center (CC) (1) · University of Arizona (1) · University of Wisconsin, Madison (1)
United States (6) · Egypt (2) · Spain (2) · Bulgaria (1) · Canada (1) · Georgia (1) · Iran (1) · Switzerland (1) · United Kingdom (1)
Bruce Barrett, MD PhD (1) · Emil Kolev, Dr. med. (1) · Gurinder Raj, MD (1) · J. David Gangemi, PhD (1) · James A Taylor (1) · James A Taylor, MD (1) · James Taylor, MD (1) · Marina Janelidze, PhD MD (1) · Mercedes Ogal, Dr. med. (1) · Michael B Aldous, MD, MPH (1) · Richard A Wahl, MD (1) · Ronald B. Turner, MD (1) · Roya Firoozi, Resident (1) · Rudolf Bauer, PhD (1)
PMID 16049208, PMID 21173411, PMID 22046723, PMID 33832544
U01AT002400 (2), R01AT001428 (1)