7 completed, 4 terminated, 3 unknown, 1 active not recruiting. 15 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Early Phase 1 | 15 | Completed 7, Terminated 4, Unknown 3, Active not recruiting 1 |
Follow Chronic Obstructive Pulmonary Disease: new trials by email Literature Review of Chronic Obstructive Pulmonary Disease trials Research Report on Chronic Obstructive Pulmonary Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Mitochondrial Derived Reactive Oxygen Species on Cardiovascular Health in Chronic Obstructive Pulmonary Disease (COPD) MitoQ, Placebo - Chronic Obstructive Pulmonary Disease | Early Phase 1 | Terminated | Virginia Commonwealth University | 4 | 2023-02-16 | 2025-02-27 |
| Electronic Cigarette-derived Oxidants and Cardiopulmonary Effects NJOY e-cigarette - Chronic Obstructive Pulmonary Disease | Early Phase 1 | Active not recruiting | Milton S. Hershey Medical Center | 30 | 2022-11-22 | 2025-10-27 |
| A Vaccine (CIMAvax-EGF) for the Prevention of Lung Cancer Development or Recurrence Quality-of-Life Assessment, Questionnaire Administration, Recombinant Human EGF-rP64K/Montanide ISA 51 Vaccine - Chronic Obstructive Pulmonary Disease, Lung Non-Small Cell Carcinoma | Early Phase 1 | Completed | Roswell Park Cancer Institute | 20 | 2021-11-22 | 2026-03-17 |
| The Effect of Inhaled Nitric Oxide on Deadspace in COPD Nitric Oxide, Placebo - Chronic Obstructive Pulmonary Disease | Early Phase 1 | Completed | Dr. Denis O'Donnell | 13 | 2021-09-01 | 2024-04-03 |
| Developing Optimal Parameters for Hyperpolarized Noble Gas and Inert Fluorinated Gas MRI of Lung Disorders HP 3He, HP 129Xe, PFP - Lung Transplant, Lung Resection | Early Phase 1 | Terminated | Thunder Bay Regional Health Research Institute | 10 | 2020-11-10 | 2024-10-15 |
| Improving Cardiovascular Health in Patients With Chronic Obstructive Pulmonary Disease Resveratrol, Placebo - Chronic Obstructive Pulmonary Disease | Early Phase 1 | Completed | Virginia Commonwealth University | 26 | 2019-07-01 | 2024-04-29 |
| Treatment of COPD by Autologous Transplantation of Bronchial Basal Cells bronchial basal cells - Chronic Obstructive Pulmonary Disease | Early Phase 1 | Unknown | First Affiliated Hospital of Shantou University Medical College | 20 | 2017-04-01 | 2017-05-17 |
| Effect iNO on Functional Respiratory Imaging in Subjects With WHO Group 3 Pulmonary Hypertension With COPD on Oxygen Inhaled Nitric Oxide 30mcg/kg IBW/hr - COPD, Pulmonary Hypertension | Early Phase 1 | Terminated | Bellerophon | 7 | 2016-10-01 | 2023-02-21 |
| TOPIC Trial for COPD Ivacaftor, Placebo - Chronic Obstructive Pulmonary Disease | Early Phase 1 | Completed | University of Alabama at Birmingham | 12 | 2015-05-01 | 2017-02-24 |
| Understanding the Importance of Plasticity in the Brain Mechanisms of Dyspnoea Perception d-cycloserine, placebo - Chronic Obstructive Pulmonary Disease | Early Phase 1 | Unknown | University of Oxford | 90 | 2013-11-01 | 2018-10-12 |
| Chronic Obstructive Pulmonary Disease Case Finding in Community-pharmacies by Spirometry Spirometry - Chronic Obstructive Pulmonary Disease | Early Phase 1 | Unknown | Col·legi de Farmacèutics de la Província de Barcelona | 3600 | 2010-10-01 | 2012-04-12 |
| Asthma & COPD Guideline Implementation Standard Practice Group (SPG), TISG - Asthma, Chronic Obstructive Pulmonary Disease | Early Phase 1 | Terminated | Laval University | 92 | 2009-09-01 | 2013-01-11 |
| Chronic Obstructive Pulmonary Disease Transcription Factor and Cytokine Study Azithromycin, Placebo - Chronic Obstructive Pulmonary Disease | Early Phase 1 | Completed | NYU Langone Health | 19 | 2009-01-01 | 2019-03-21 |
| The Effects of Tiotropium on the Cough Reflex in Patients With Chronic Obstructive Pulmonary Disease (COPD) Tiotropium - Chronic Obstructive Pulmonary Disease, Chronic Bronchitis | Early Phase 1 | Completed | ThomasTruncale | 5 | 2008-02-01 | 2014-10-01 |
| Osteopathy in Chronic Obstructive Pulmonary Disease (COPD) Rehabilitation Trial Active osteopathic treatment (OMT+PR): Active Comparator, sham osteopathic treatment (SOT+PR) - Chronic Obstructive Pulmonary Disease | Early Phase 1 | Completed | Fondazione Salvatore Maugeri | 20 | 2008-01-01 | 2011-10-24 |
Pulmonary Disease, Chronic Obstructive (15) · Asthma (2) · Dyspnea (2) · Hypertension, Pulmonary (2) · Lung Neoplasms (2) · Asbestosis (1) · Bronchiectasis (1) · Bronchitis, Chronic (1) · Carcinoma, Non-Small-Cell Lung (1) · Cystic Fibrosis (1) · Emphysema (1) · Lung Diseases (1) · Lung Diseases, Interstitial (1) · Mesothelioma (1) · Motor Activity (1)
Chronic Disease (15) · Disease Attributes (15) · Lung Diseases, Obstructive (15) · Pathologic Processes (15) · Pathological Conditions, Signs and Symptoms (15) · Respiratory Tract Diseases (15) · Lung Diseases (14) · Bronchial Diseases (3) · Respiration Disorders (3) · Cardiovascular Diseases (2) · Hypersensitivity (2) · Hypersensitivity, Immediate (2) · Hypertension (2) · Immune System Diseases (2) · Infections (2)
Azithromycin (1) · CIMAvax EGF (1) · Cycloserine (1) · Inosine (1) · Nitric Oxide (1) · Resveratrol (1) · Sulfur Hexafluoride (1) · Tiotropium Bromide (1) · ivacaftor (1) · mitoquinone (1) · perflutren (1)
Virginia Commonwealth University (2) · Bellerophon (1) · Col·legi de Farmacèutics de la Província de Barcelona (1) · Dr. Denis O'Donnell (1) · First Affiliated Hospital of Shantou University Medical College (1) · Fondazione Salvatore Maugeri (1) · Laval University (1) · Milton S. Hershey Medical Center (1) · NYU Langone Health (1) · Roswell Park Cancer Institute (1) · ThomasTruncale (1) · Thunder Bay Regional Health Research Institute (1) · University of Alabama at Birmingham (1) · University of Oxford (1)
United States (6) · Canada (3) · Belgium (1) · China (1) · Italy (1) · Spain (1) · United Kingdom (1)
Ashika Ahmed, MD (1) · Denis E O'Donnell, MD (1) · Diego Castillo, MD (1) · Ercole Zanotti, md (1) · Kyle TS Pattinson, BM DPhil FRCA (1) · Louis-Philippe Boulet, MD, FRCPC (1) · Mary Reid, PhD (1) · Mitchell S Albert, PhD (1) · Paula Rodriguez Miguelez, PhD (1) · Paula Rodriguez-Miguelez, PhD (1) · Raghu Sinha, PhD (1) · Rebecca Bascom, MD (1) · Thoms Truncale, DO,MPH (1)
PMID 27486204, PMID 35584850, PMID 35762891, PMID 36572534, PMID 37020840, PMID 40455920
R01HL152436 (1)