18 completed, 7 recruiting, 4 terminated, 4 unknown. 19 Not applicable, 17 Phase 2, 5 Phase 1, 2 Early Phase 1, 1 Phase 3.
Follow mitoquinone: new trials by email Literature Review of mitoquinone trials Research Report on mitoquinone
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Role of Endothelial Dysfunction on Exercise Pressor Reflex in Type 2 Diabetes MitoQ (mitoquinol mesylate), Placebo - Type 2 Diabetes (T2DM), Endothelial Dysfunction | Not applicable | Not yet recruiting | Medical College of Wisconsin | 40 | 2027-10-01 | 2026-10-30 |
| Efficacy and Safety of MitoQ in Improving Cancer Cachexia MitoQ (mitoquinol mesylate) - Cancer Cachexia (CC), Cancer Patients With Solid Tumors | Phase 2 | Not yet recruiting | The First Affiliated Hospital of Xinxiang Medical College | 20 | 2026-10-10 | 2026-09-23 |
| Oral Antioxidant Therapy Targeted to the Mitochondria for Improving Brain Artery Health in Postmenopausal Women Mitoquinone (MitoQ), Placebo - Aging, Postmenopause | Not applicable | Not yet recruiting | Colorado State University | 86 | 2026-04-01 | 2026-02-12 |
| Probing the Role of Mitochondrial Oxidative Stress in Impaired Vascular Function Among Young Adults With Early Life Adversity Mitoquinone mesylate (MitoQ), Placebo - Adverse Childhood Experience, Endothelial Function (FMD) | Not applicable | Recruiting | University of Iowa | 300 | 2025-10-13 | 2025-11-24 |
| Mini-MARVEL - Mitochondrial Antioxidant Therapy in Ulcerative Colitis MitoQ, Placebo - Ulcerative Colitis | Phase 2 | Withdrawn | University of Edinburgh | 2025-09-01 | 2026-01-09 | |
| WinQ : a Window of Opportunity Study With MitoQ in Breast Cancer MitoQ (mitoquinol mesylate) - Breast Cancer | Not applicable | Recruiting | Université Catholique de Louvain | 20 | 2025-07-20 | 2025-08-26 |
| The Mito-Frail Trial: Effects of MitoQ on Vasodilation, Mobility and Cognitive Performance in Frail Older Adults Mitoquinone Mesylate, Placebo capsule - Frailty, Mild Cognitive Impairment | Phase 2 | Recruiting | UConn Health | 60 | 2024-10-07 | 2026-08-12 |
| The Influence of Race and MitoQ Supplementation on Skin Blood Flow in the Cold Mitoquinone mesylate (MitoQ), Placebo, Cold Water Hand Immersion - Cold Exposure | Not applicable | Completed | United States Army Research Institute of Environmental Medicine | 26 | 2024-09-16 | 2026-04-30 |
| Effects of an Antioxidant Supplement on Blood Vessel Health MitoQ, Placebo, MitoTempo - Healthy | Phase 2 | Recruiting | University of Georgia | 60 | 2024-07-01 | 2024-12-09 |
| ROAR-DIGAP: A Widely Inclusive, Largely Virtual Pilot Trial Utilizing DIGAP (Deep Integrated Genomics Analysis Platform) To Personalize Treatments Astaxanthin, Protandim, Melatonin - Amyotrophic Lateral Sclerosis ALS | Phase 2 | Completed | Duke University | 50 | 2024-06-12 | 2026-10-27 |
| MitoQ for Early-phase Schizophrenia-spectrum Disorder and Mitochondrial Dysfunction MitoQ, Placebo - Schizophrenia and Related Disorders, Mitochondrial Alteration | Phase 2 / Phase 3 | Recruiting | Mclean Hospital | 100 | 2024-06-01 | 2025-09-25 |
| Testing MitoQ on Lower Urinary Tract Symptoms in Older Women With Metabolic Syndrome MitoQ (mitoquinol mesylate), Placebo - Lower Urinary Tract Symptoms, Overactive Bladder Syndrome | Phase 2 | Terminated | Iman Al-Naggar, PhD | 20 | 2024-04-03 | 2026-05-01 |
| Mitoquinone/Mitoquinol Mesylate as Oral and Safe Postexposure Prophylaxis for Covid-19 Mitoquinone/mitoquinol mesylate, Placebo - SARS-CoV Infection, COVID-19 | Phase 2 | Completed | University of Texas Southwestern Medical Center | 122 | 2024-03-01 | 2026-09-21 |
| Mitochondrial Derived Reactive Oxygen Species on Cardiovascular Health in Chronic Obstructive Pulmonary Disease (COPD) MitoQ, Placebo - Chronic Obstructive Pulmonary Disease | Early Phase 1 | Terminated | Virginia Commonwealth University | 4 | 2023-02-16 | 2025-02-27 |
| MitoQ and Exercise Effects on Vascular Health MitoQ, Placebo, Aerobic exercise - Aging, Menopause | Early Phase 1 | Active not recruiting | University of Colorado, Denver | 22 | 2023-01-16 | 2025-03-25 |
| Mitochondria Oxidative Stress and Vascular Health Study MitoQ - Cardiovascular Diseases, Hypertension | Not applicable | Completed | Auburn University | 31 | 2022-12-06 | 2025-09-29 |
| Long-term COVID and Rehabilitation Mitoquinone, Placebo - Long-COVID | Not applicable | Recruiting | VA Office of Research and Development | 300 | 2022-11-01 | 2026-07-30 |
| Role of Mitochondrial-derived Oxidative Stress to Promote Vascular Endothelial Dysfunction in Non-exercisers With Aging Placebo, Mitoquinone Mesylate - Aging, Endothelial Dysfunction | Not applicable | Completed | Ball State University | 23 | 2022-09-23 | 2023-05-24 |
| MitoQ & Cardiopulmonary Responses During Exercise MitoQ, Placebo - Healthy | Not applicable | Completed | Ball State University | 9 | 2022-09-14 | 2023-10-05 |
| Examining the Effects of Mitochondrial Oxidative Stress in DCM MitoQ Compound, Placebo - Dilated Cardiomyopathy | Phase 2 | Completed | Imperial College London | 53 | 2022-07-26 | 2025-09-18 |
Showing 20 of 41. Sign in to see all of them.
Hypertension (4) · Cardiovascular Diseases (3) · Cognitive Dysfunction (3) · Breast Neoplasms (2) · COVID-19 (2) · Fatigue (2) · Multiple Sclerosis (2) · Pulmonary Disease, Chronic Obstructive (2) · Renal Insufficiency, Chronic (2) · Alzheimer Disease (1) · Amyotrophic Lateral Sclerosis (1) · Anemia, Sickle Cell (1) · Asthma (1) · Cardiomyopathy, Dilated (1) · Cardiotoxicity (1)
Antipodean Pharmaceuticals, Inc. (3) · Auburn University (2) · Ball State University (2) · University of Colorado, Boulder (2) · University of Colorado, Denver (2) · University of Copenhagen (2) · University of Edinburgh (2) · University of Nebraska (2) · VA Office of Research and Development (2) · Virginia Commonwealth University (2) · Colorado State University (1) · D'Or Institute for Research and Education (1) · D. Walter Wray (1) · Duke University (1) · Iman Al-Naggar, PhD (1)
United States (29) · United Kingdom (4) · Denmark (2) · New Zealand (2) · Australia (1) · Belgium (1) · Switzerland (1)
Danielle L Kirkman, PhD (2) · Allan Kluser Sales, PhD (1) · Anne E Dixon, MD (1) · Austin T Robinson, PhD (1) · Barry J Snow, MD (1) · Brad Fleenor, PhD (1) · Brian Halliday, MBChB PhD (1) · Chris Day, MD, PhD (1) · David G Edwards, PhD (1) · David W Wray, Ph.D. (1) · David Wilson, MD (1) · Dost Ongur, MD, PhD (1) · Douglas R Seals (1) · Douglas R Seals, PhD (1) · Edward J Gane, MBChB (1)
PMID 20492507, PMID 29661838, PMID 36187760, PMID 38471990, PMID 38568933, PMID 39873709, PMID 40603760, PMID 41264372, PMID 42420763
K01AG080164 (1), K01HL177339 (1), P30AG067988 (1), R01AG066730 (1), R56AG072094 (1)