225 completed, 84 terminated, 59 recruiting, 40 withdrawn. 168 Phase 2, 143 Phase 1, 132 Not applicable, 14 Early Phase 1, 7 Phase 3.
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Temozolomide and Survivin Long Peptide Vaccine (SurVaxM) for the Treatment of Patients With Progressing Metastatic Neuroendocrine Carcinomas Biospecimen Collection, Computed Tomography, Incomplete Freund''s Adjuvant - Digestive System Neuroendocrine Neoplasm, Lung Neuroendocrine Neoplasm | Phase 2 | Not yet recruiting | Roswell Park Cancer Institute | 60 | 2026-12-15 | 2026-10-20 |
| Phase I Trial of Pacritinib in Combination With Venetoclax and Azacitidine for the Treatment of Accelerated and Blast Phase Myeloproliferative Neoplasms Pacritinib, Venetoclax, Azacitidine - Myeloproliferative Neoplasm | Phase 1 | Not yet recruiting | Roswell Park Cancer Institute | 20 | 2026-12-01 | 2026-10-21 |
| Community-Based Exercise and Nutrition Training and Education Program for Cancer Survivors Exercise Intervention, Medical Device Usage and Evaluation, Nutritional Intervention - Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm | Not applicable | Recruiting | Roswell Park Cancer Institute | 150 | 2026-12-01 | 2026-10-21 |
| Nemtabrutinib and Pembrolizumab for the Treatment of Richter Transformation, Diffuse Large B-cell Lymphoma Subtype Biospecimen Collection, Bone Marrow Biopsy, Computed Tomography - Richter Syndrome, Diffuse Large B-Cell Lymphoma | Phase 2 | Recruiting | Roswell Park Cancer Institute | 32 | 2026-11-15 | 2026-10-02 |
| A Food Security Intervention for the Prevention of Cancer in Low-income Families Food Assistance Programs, Health Promotion and Education, Questionnaire Administration - Obesity-Related Malignant Neoplasm | Not applicable | Suspended | Roswell Park Cancer Institute | 50 | 2026-11-15 | 2026-09-15 |
| Autologous CAR T Cells Targeting GPC3 (RPCAR01) for the Treatment of Advanced or Metastatic GPC3 Expressing Hepatocellular Carcinoma Anti-GPC3-CAR Autologous T Lymphocytes, Biospecimen Collection, Computed Tomography - Advanced Hepatocellular Carcinoma, Metastatic Hepatocellular Carcinoma | Phase 1 | Suspended | Roswell Park Cancer Institute | 24 | 2026-11-15 | 2026-09-15 |
| Comparing Two Weight Loss Programs for the Prevention of Kidney Cancer Progression Among Patients With Small Renal Masses on Active Surveillance Intermittent Fasting, Continuous Energy Restriction (CER) - Renal Cell Carcinoma (RCC) | Not applicable | Recruiting | Roswell Park Cancer Institute | 20 | 2026-11-01 | 2026-10-16 |
| Chatbot Utilization for Pedigree Creation and Cancer Risk Assessment in Cancer Genetic Counseling Text Message -based Navigation Intervenion, Artificial Intelligence based Intervention - Hereditary Breast Carcinoma, Hereditary Malignant Neoplasm | Not applicable | Not yet recruiting | Roswell Park Cancer Institute | 129 | 2026-11-01 | 2026-10-21 |
| CIMAvax-EGF With KRAS G12C Inhibitor for the Treatment of Advanced, KRAS G12C Mutated Non Small Cell Lung Cancer Adagrasib, Biospecimen Collection, Computed Tomography - Advanced Lung Non-Small Cell Carcinoma, Stage III Lung Cancer AJCC v8 | Phase 2 | Not yet recruiting | Roswell Park Cancer Institute | 29 | 2026-10-15 | 2026-09-02 |
| Evaluating the Delivery and Effects of THC Vaping Liquids in the Bloodstream Biospecimen Collection, Cannabis sativa Extract, Nicotine - Cannabis Dependence | Early Phase 1 | Not yet recruiting | Roswell Park Cancer Institute | 60 | 2026-10-15 | 2026-09-25 |
| Bispecific CD19/CD20-Targeted Chimeric Antigen Receptor (CAR) Modified T Cells With 4-1BB and Mutated CD28 Costimulatory Domains in Patients With Relapsed or Refractory CD19+ Hematologic Malignancies 20-19 Tan BB06oz CAR T - Hematologic Diseases | Phase 1 | Not yet recruiting | Roswell Park Cancer Institute | 21 | 2026-10-01 | 2026-07-15 |
| Mind-Body Interventions for the Improvement of Quality of Life, Stress, and Sleep Quality Among Survivors of Breast, Prostate, Endometrial, or Colorectal Cancer Media Intervention, Mind-body intervention, Meditation Therapy - Breast Cancer Stage I, Colorectal Cancer | Not applicable | Not yet recruiting | Roswell Park Cancer Institute | 30 | 2026-09-30 | 2026-08-04 |
| Understanding Tobacco and Cannabis Co-Use Practices: Initiation, Escalation, and Maintenance Non-Interventional Study - Cigarette Smoking-Related Carcinoma | Recruiting | Roswell Park Cancer Institute | 40 | 2026-09-28 | 2026-08-17 | |
| PK/PD of Vaping THC-containing Liquids vs. Smoked Cannabis Vape device, Joint, Marijuana via vape device - Cigarette Smoking-Related Carcinoma | Phase 1 | Not yet recruiting | Roswell Park Cancer Institute | 40 | 2026-09-15 | 2026-08-12 |
| Home-Based Respiratory Muscle Training and Aerobic Exercise Programs to Improve Lung Health in Current and Former Cigarette Smokers Accelerometry, Aerobic Exercise, Biospecimen Collection - Lung Carcinoma | Not applicable | Not yet recruiting | Roswell Park Cancer Institute | 200 | 2026-09-15 | 2026-08-21 |
| Psilocybin With Psychotherapy for Improving Chronic Pain in Cancer Patients Requiring Opioids Biospecimen Collection, Functional Magnetic Resonance Imaging, Interview - Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm | Phase 2 | Not yet recruiting | Roswell Park Cancer Institute | 20 | 2026-09-15 | 2026-08-12 |
| Hotspot Stereotactic Ablative Radiotherapy Versus Traditional Stereotactic Ablative Radiotherapy for the Treatment of Early-Stage Non-Small Cell Lung Cancer Biospecimen Collection, Computed Tomography, Lymph Node Biopsy - Early Stage Lung Non-Small Cell Carcinoma, Stage I Lung Cancer AJCC v8 | Phase 2 | Recruiting | Roswell Park Cancer Institute | 200 | 2026-09-01 | 2026-08-26 |
| Transperineal Micro-ultrasound for the Detection of Prostate Cancer During Biopsy Biopsy of Prostate, Magnetic Resonance Imaging, Micro-ultrasound Imaging - Prostate Carcinoma | Not applicable | Recruiting | Roswell Park Cancer Institute | 138 | 2026-08-18 | 2026-09-11 |
| GB-5267 for the Treatment Platinum-Resistant Ovarian, Peritoneal, or Fallopian Tube Cancer GB-5267 - IV only, GB-5267 -Combined IV and IP Infusion - Platinum-resistant Ovarian Cancer | Phase 1 | Recruiting | Roswell Park Cancer Institute | 18 | 2026-08-18 | 2026-09-16 |
| Photoimmunotherapy With ASP-1929 and Cemiplimab for the Treatment of Refractory, Inoperable, and Metastatic Stage IIIB-IV Non-small Cell Lung Cancer Biospecimen Collection, Cemiplimab, Cetuximab Sarotalocan Sodium - Lung Non-Small Cell Carcinoma, Metastatic Lung Non-Small Cell Carcinoma | Phase 2 | Withdrawn | Roswell Park Cancer Institute | 2026-08-15 | 2026-09-15 |
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Carcinoma, Non-Small-Cell Lung (38) · Lung Neoplasms (37) · Prostatic Neoplasms (33) · Leukemia, Myeloid, Acute (31) · Breast Neoplasms (27) · Colorectal Neoplasms (25) · Leukemia, Lymphocytic, Chronic, B-Cell (23) · Multiple Myeloma (23) · Leukemia (22) · Ovarian Neoplasms (20) · Lymphoma (19) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (19) · Fallopian Tube Neoplasms (18) · Lymphoma, Large B-Cell, Diffuse (18) · Squamous Cell Carcinoma of Head and Neck (18)
Specimen Handling (29) · Magnetic Resonance Spectroscopy (25) · Cyclophosphamide (22) · Biopsy (20) · pembrolizumab (19) · Radiotherapy (18) · 2-(1-hexyloxyethyl)-2-devinyl pyropheophorbide-a (16) · Gemcitabine (15) · Capecitabine (14) · Dexamethasone (14) · Irinotecan (14) · Oxaliplatin (14) · Practice Guidelines as Topic (13) · Standard of Care (13) · Carboplatin (12)
United States (426) · Canada (2) · Netherlands (1) · New Zealand (1) · Nigeria (1)
Anurag Singh (10) · Marwan Fakih, MD (10) · Anurag K Singh (8) · Donald L. Trump, MD (8) · Philip L. McCarthy, MD (8) · Renuka Iyer (7) · Renuka Iyer, MD (7) · Barbara Jean Bambach, MD (6) · Christos Fountzilas (6) · Emese Zsiros (6) · Alex Adjei (5) · Elizabeth Bouchard (5) · Kunle Odunsi (5) · Martin Mahoney (5) · Nithya Ramnath, MD (5)
PMID 40132910, PMID 37142273, PMID 12356141, PMID 1438661, PMID 14639062, PMID 16051743, PMID 16086046, PMID 17404091, PMID 17426973, PMID 17989978, PMID 18565686, PMID 18594219, PMID 18845990, PMID 19091347, PMID 19491904, PMID 19528374, PMID 19556464, PMID 19687399, PMID 22116638, PMID 22273276, PMID 23132334, PMID 23868427, PMID 24285015, PMID 24552630, PMID 24669750, PMID 24995027, PMID 25209242, PMID 25424850, PMID 25964296, PMID 27441995, PMID 27984559, PMID 28577548, PMID 28630212, PMID 28674120, PMID 28900756, PMID 28915895, PMID 29343557, PMID 29355886, PMID 29595298, PMID 30178239, PMID 30339877, PMID 30486865, PMID 30497431, PMID 30561642, PMID 30672147, PMID 30677214, PMID 30715996, PMID 30824630, PMID 31296931, PMID 31391334
P30CA016056 (51), U54CA228110 (4), P01CA234212 (3), P50CA159981 (3), P01CA055791 (2), P01CA217806 (2), R01CA158318 (2), R01CA204636 (2), R01CA258337 (2), R01DA054276 (2), R01DA057228 (2), R21CA289541 (2), UL1TR001412 (2), K07CA148888 (1), K43TW011995 (1)