5 completed, 2 recruiting, 2 terminated, 2 unknown. 6 Not applicable, 3 Phase 3, 2 Phase 2, 2 Phase 4, 1 Early Phase 1.
Follow Sulfur Hexafluoride: new trials by email Literature Review of Sulfur Hexafluoride trials Research Report on Sulfur Hexafluoride
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Air Tamponade Versus Fluorinated Gas Tamponade for Rhegmatogenous Retinal Detachment air, Gas SF6 (Sulfur Hexafluoride) and others - Retinal Detachment Rhegmatogenous | Not applicable | Not yet recruiting | Liverpool University Hospitals NHS Foundation Trust | 150 | 2026-03-20 | 2025-12-24 |
| Y-90 Treatment Response Using Transarterial Radioembolization Lumason, Sonazoid - HCC, Hepatocellular Carcinoma | Phase 2 | Recruiting | Thomas Jefferson University | 30 | 2025-09-11 | 2026-06-10 |
| Neonatal Brain Ultrasound With CEUS and Elastography Brain contrast enhanced ultrasound, brain ultrasound elastography, Sulfur Hexafluoride - Neonatal Hypoxic Ischemic Encephalopathy, Neonatal Stroke | Phase 3 | Recruiting | Turku University Hospital | 100 | 2024-01-01 | 2026-01-15 |
| Preterm Neonates Brain Ultrasound With CEUS and Elastography Brain contrast enhanced ultrasound, brain ultrasound elastography, Sulfur Hexafluoride - Prematurity | Phase 3 | Withdrawn | Turku University Hospital | 2024-01-01 | 2026-01-15 | |
| Developing Optimal Parameters for Hyperpolarized Noble Gas and Inert Fluorinated Gas MRI of Lung Disorders HP 3He, HP 129Xe, PFP - Lung Transplant, Lung Resection | Early Phase 1 | Terminated | Thunder Bay Regional Health Research Institute | 10 | 2020-11-10 | 2024-10-15 |
| Accuracy of Contrast-Enhanced Ultrasound for Hepatocellular Carcinoma Post TACE Lumason - Hepatocellular Carcinoma | Phase 4 | Completed | Milton S. Hershey Medical Center | 26 | 2020-10-14 | 2023-11-02 |
| Multiparametric Ultrasound Imaging in Prostate Cancer SonoVue - Prostate Cancer, Prostatic Neoplasms | Not applicable | Unknown | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 200 | 2017-09-07 | 2019-01-17 |
| Ultrasound Evaluation of Crohn's Disease Sulfur Hexafluoride, Ultrasound Elastography, Ultrasound Vascularity - Crohn Disease | Phase 4 | Terminated | Mayo Clinic | 9 | 2017-06-16 | 2021-11-10 |
| Corneal Endothelial Cell Loss After Pneumatic Retinopexy for the Repair of Primary Rhegmatogenous Retinal Detachment Pneumatic retinopexy, vitrectomy, sulfur hexafluoride (SF6) - Rhegmatogenous Retinal Detachment | Not applicable | Unknown | Sunnybrook Health Sciences Centre | 30 | 2014-07-01 | 2014-07-09 |
| Mechanisms of Pharyngeal Collapse in Sleep Apnea, Study C Administration of gas mixtures - Sleep Apnea | Not applicable | Withdrawn | Brigham and Women's Hospital | 2012-12-08 | 2019-07-11 | |
| Sonothrombolysis Potentiated by Microbubbles for Acute Ischemic Stroke Sulfur hexafluoride + ultrasounds, Recombinant tissue plasminogen activator - Cerebrovascular Stroke | Phase 2 | Completed | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | 24 | 2012-08-01 | 2015-08-10 |
| Contrast-enhanced Ultrasound (CE-US) and Magnetic Resonance Imaging (MRI): Evaluating Plaque Neovascularisation sulphur hexafluoride, gadopentate dimeglumine - Carotid Artery Stenosis, Atherosclerosis | Not applicable | Completed | Maastricht University Medical Center | 18 | 2009-06-01 | 2011-04-20 |
| Intracameral Gas SF6 (Sulfur Hexafluoride) Injection for Acute Hydrops in Keratoconus Gas SF6 (Sulfur Hexafluoride) - Hydrops in Keratoconus | Not applicable | Completed | HaEmek Medical Center, Israel | 8 | 2008-01-01 | 2020-02-17 |
| The Silicone Study Perfluoropropane, Sulfur Hexafluoride, Silicone Oil - Proliferative Vitreoretinopathy, Retinal Detachment | Phase 3 | Completed | National Eye Institute (NEI) | 1985-09-01 | 2005-06-24 |
Carcinoma, Hepatocellular (2) · Retinal Detachment (2) · Arteriosclerosis (1) · Asbestosis (1) · Asthma (1) · Atherosclerosis (1) · Bronchiectasis (1) · Carcinoma (1) · Carotid Stenosis (1) · Corneal Endothelial Cell Loss (1) · Crohn Disease (1) · Cystic Fibrosis (1) · Emphysema (1) · Hypertension, Pulmonary (1) · Liver Neoplasms (1)
Turku University Hospital (2) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Brigham and Women's Hospital (1) · Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau (1) · HaEmek Medical Center, Israel (1) · Liverpool University Hospitals NHS Foundation Trust (1) · Maastricht University Medical Center (1) · Mayo Clinic (1) · Milton S. Hershey Medical Center (1) · National Eye Institute (NEI) (1) · Sunnybrook Health Sciences Centre (1) · Thomas Jefferson University (1) · Thunder Bay Regional Health Research Institute (1)
United States (4) · Canada (2) · Finland (2) · Netherlands (2) · Israel (1) · Spain (1)
Jussi Hirvonen (2) · Riitta Parkkola (2) · Tiina Laurikainen (2) · Vilhelmiina Parikka (2) · David A Wellman, MD (1) · H. Wijkstra, Prof dr ir (1) · John Eisenbrey, PhD (1) · Kathryn McGillen (1) · Mitchell S Albert, PhD (1) · Peter Kertes, MD, CM, FRCSC (1) · Rumana N Hussain, MBBS, FRCOph (1) · Shigao Chen, PhD (1) · Werner H Mess, MD, PhD (1)
PMID 32408387, PMID 35584850, PMID 35762891
R01HL102321 (1), R21CA303648 (1)