9 completed, 5 recruiting, 4 not yet recruiting, 4 unknown. 22 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 22 | Completed 9, Recruiting 5, Not yet recruiting 4, Unknown 4 |
Follow Children: new trials by email Literature Review of Children trials Research Report on Children
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparing Esketamine and Remazolam With Propofol for Breathing Safety in Pediatric Gastroscopy Fentanyl and Propofol, Esketamine and remimazolam - Adverse Respiratory Events, Hypoxemia | Phase 4 | Not yet recruiting | Second Affiliated Hospital of Wenzhou Medical University | 120 | 2026-08-01 | 2026-08-06 |
| Vitamin D2 vs Vitamin D2 Plus Calcitriol in Cholestatic Children With Vitamin D Deficiency Vitamin D2, Calcitriol - Cholestatic Liver Disease, Chronic Liver Disease (CLD) | Phase 4 | Recruiting | Chulalongkorn University | 54 | 2026-04-28 | 2026-08-03 |
| Intranasal Dexmedetomidine-esketamine Administration and Postoperative Pain in Pediatric Patients Intranasal dexmedetomidine-esketamine, Intranasal placebo (normal saline) - Adenotonsillectomy, Children | Phase 4 | Recruiting | Peking University First Hospital | 160 | 2026-04-07 | 2026-04-09 |
| Entecavir With or Without Pegylated Interferon α-2b in Children Aged 3-6 Years With Immune-Tolerant Chronic Hepatitis B Entecavir, Entecavir + Pegylated interferon α-2b - Hepatitis B Virus Infection, Children | Phase 4 | Not yet recruiting | Qing-Lei Zeng | 80 | 2026-01-11 | 2026-01-16 |
| Entecavir With or Without Pegylated Interferon α-2b in Children Aged 3-6 Years With Immune-Active Chronic Hepatitis B Entecavir, Entecavir + Pegylated interferon α-2b - Hepatitis B Virus Infection, Children | Phase 4 | Not yet recruiting | Qing-Lei Zeng | 60 | 2026-01-11 | 2026-01-16 |
| The Efficacy of Melatonin Patches on Dental Anxiety in Children Melatonin Patches, Placebo Group - Dental Anxiety, Children | Phase 4 | Completed | Ain Shams University | 52 | 2025-06-25 | 2025-11-13 |
| Optimizing Perioperative Analgesia to Lower Pain Following Cleft Palate Surgery Methadone hydrochloride, Fentanyl/Hydromorphone - Cleft Palate, Pain | Phase 4 | Recruiting | Duke University | 60 | 2025-06-04 | 2026-04-14 |
| Determination of ED50 and ED95 With Clinical Efficacy of Intranasal Dexmedetomidine Combined With Esketamine for Preoperative Sedation in Pediatric General Anesthesia dexmedetomidine, Esketamine - Preoperative Anxiety, Preoperative Sedation | Phase 4 | Recruiting | Second Affiliated Hospital of Wenzhou Medical University | 80 | 2025-03-01 | 2025-12-02 |
| Combined Application of EEN in the Induction of Remission in PUC exclusive enteral nutrition, regular food - Exclusive Enteral Nutrition, Ulcerative Colitis | Phase 4 | Not yet recruiting | Children's Hospital of Fudan University | 40 | 2025-03-01 | 2024-07-03 |
| A Comparative Study of Adding Ipratropium to Salbutamol for the Treatment of Asthma Attack in Children Salbutamol (Ventolin®), salbutamol + ipratropium bromide nebules - Asthma Exacerbation, Children | Phase 4 | Completed | Children's Hospital and Institute of Child Health, Multan | 60 | 2024-01-01 | 2025-04-09 |
| Low Concentration Atropine Combined With Soft Contact Lens in Controlling Myopia Progression in Children With High Myopia soft peripheral defocus contact lenses, Atropine 0.04%, Atropine (0.01%) - High Myopia, Low Concentration Atropine | Phase 4 | Completed | Beijing Tongren Hospital | 120 | 2023-06-30 | 2026-02-12 |
| Safety and Efficacy Evaluation of S (+) - Ketamine in Children Conventional therapy + S (+)-Ketamine, Conventional therapy - S-ketamine, Esketamine | Phase 4 | Unknown | Chinese PLA General Hospital | 3000 | 2022-04-20 | 2024-03-08 |
| Top Down Versus Step up in Pediatric Ulcerative Colitis Infliximab, Corticosteroids - Ulcerative Colitis, Infliximab | Phase 4 | Recruiting | Children's Hospital of Fudan University | 40 | 2021-11-01 | 2024-02-28 |
| Exploration of the Optimal Dosage of Cetirizine in the Treatment of Allergic Diseases in Chinese Children 1-3 Cetirizine Pharmacokinetic samples - Allergic Disease, Children | Phase 4 | Unknown | Peking University Third Hospital | 80 | 2020-08-06 | 2024-03-01 |
| Pre-emptive Scalp Infiltration With Dexamethasone Plus Ropivacaine for Post-Craniotomy Pain in Children The dexamethasone plus ropivacaine, The ropivacaine - Pain, Postoperative, Children | Phase 4 | Completed | Beijing Tiantan Hospital | 80 | 2019-09-02 | 2020-07-21 |
| Vaccine Campaign Effects on General Hospital Admissions and Mortality Among Children Measles vaccine, Oral polio vaccine - Measles Vaccination, Oral Polio Vaccine | Phase 4 | Completed | Bandim Health Project | 28612 | 2016-11-01 | 2024-09-03 |
| Buccal Midazolam Versus Nasal or Oral Midazolam Sedation for Minor Invasive Procedures in Children Midazolam - Dormicum, Conscious Sedation | Phase 4 | Unknown | Carmel Medical Center | 90 | 2015-04-01 | 2015-04-09 |
| Insufflation in Children Undergoing Colonoscopy CO2, air - Colonoscopy, Children | Phase 4 | Completed | University Medical Centre Ljubljana | 78 | 2015-03-01 | 2015-12-15 |
| Effects of Montelukast in Asthmatic Children With and Without Food Allergy Montelukast - Bronchial Asthma, Food Allergy | Phase 4 | Completed | Hacettepe University | 113 | 2013-03-01 | 2017-08-14 |
| Evaluation of a Family Intervention Program for the Management of Overweight or Obese Children Counselling group, Nereu group - Overweight, Obesity | Phase 4 | Unknown | Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina | 100 | 2013-01-01 | 2013-06-17 |
Showing 20 of 22. Sign in to see all of them.
Pain, Postoperative (3) · Agnosia (2) · Asthma (2) · Bronchiolitis Obliterans Syndrome (2) · Colitis, Ulcerative (2) · Hepatitis B (2) · Hepatitis B, Chronic (2) · Abdominal Pain (1) · Acute Pain (1) · Anxiety Disorders (1) · Behavior (1) · Cholestasis (1) · Cleft Palate (1) · Delirium (1) · Depression (1)
Pathological Conditions, Signs and Symptoms (11) · Signs and Symptoms (7) · Pathologic Processes (6) · Digestive System Diseases (5) · Neurologic Manifestations (5) · Bronchial Diseases (4) · Immune System Diseases (4) · Lung Diseases (4) · Lung Diseases, Obstructive (4) · Pain (4) · Respiratory Tract Diseases (4) · Postoperative Complications (3) · Blood-Borne Infections (2) · Bronchiolitis (2) · Bronchiolitis Obliterans (2)
Esketamine (3) · Adrenal Cortex Hormones (2) · Fentanyl (2) · Infliximab (2) · Mesalamine (2) · Saline Solution (2) · entecavir (2) · Air (1) · Albuterol (1) · Atropine (1) · Calcitriol (1) · Dexmedetomidine (1) · Ergocalciferols (1) · Hydromorphone (1) · Ipratropium (1)
Children's Hospital of Fudan University (2) · Qing-Lei Zeng (2) · Second Affiliated Hospital of Wenzhou Medical University (2) · Ain Shams University (1) · Bandim Health Project (1) · Beijing Tiantan Hospital (1) · Beijing Tongren Hospital (1) · Carmel Medical Center (1) · Children's Hospital and Institute of Child Health, Multan (1) · Chinese PLA General Hospital (1) · Chulalongkorn University (1) · Duke University (1) · Federal University of São Paulo (1) · Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina (1) · Hacettepe University (1)
China (8) · Turkey (Türkiye) (2) · Brazil (1) · Egypt (1) · Guinea-Bissau (1) · Israel (1) · Pakistan (1) · Slovenia (1) · Spain (1) · Thailand (1) · United States (1)
Qing-Lei Zeng, M.D. (2) · Ying Huang (2) · Aksel Jensen, PhD (1) · Amabelia Rodrigues, Ph (1) · Ana LA Giraldes, MD (1) · Ane Fisker, MD, PhD (1) · Anshu Varma, MSc (1) · Ayfer Tuncer, Professor (1) · Betul Buyuktiryaki, MD, fellow (1) · Cansin Sackesen, Assoc Prof (1) · Dong-Xin Wang, MD, PhD (1) · Dr. Muhammad Aslam Sheikh, FCPS (1)
PMID 24153001, PMID 26363332, PMID 26658988, PMID 31711464, PMID 32897359, PMID 35870990