922 completed, 389 unknown, 115 recruiting, 100 terminated. 334 Phase 4, 302 Phase 2, 261 Phase 3, 218 Phase 1, 215 Not applicable.
Follow Hepatitis B: new trials by email Literature Review of Hepatitis B trials Research Report on Hepatitis B
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Managing Hepatitis B (Hep. B) and Human Papilloma Virus (HPV) Related Cancers and Mental Health. Gardasil 9 vaccine, Hepatitis B Virus Vaccine(HBV), Cognitive Behavioral Therapy - Hepatitis B, Human Papilloma Virus | Phase 4 | Not yet recruiting | Eunice Dube | 2140 | 2027-01-30 | 2026-07-30 |
| Combating Related Epidemics in HCV Cepheid GeneXpert HCV Test, Abbott Determine HIV - 1/2 Ag/Ab, Abbott Determine HbsAg 2 - HIV - Human Immunodeficiency Virus, Hepatitis B Virus (HBV) | Phase 4 | Not yet recruiting | Duke University | 1280 | 2027-01-20 | 2026-10-15 |
| B-Ensure: Long-term Follow-up Study to Evaluate Durability of Treatment Response in Previous Bepirovirsen Study Participants Bepirovirsen - Hepatitis B | Phase 4 | Not yet recruiting | GlaxoSmithKline | 303 | 2026-12-03 | 2026-11-02 |
| Targeting ANKRD11 Reverses HBV-Specific CD8+ T Cell Dysfunction and Tolerance Chronic Hepatitis B | Not yet recruiting | Beijing Municipal Administration of Hospitals | 40 | 2026-12-01 | 2026-08-28 | |
| A Prospective Study to Evaluate the Efficacy and Safety of Entecavir ODT Conversion in Stable Liver Transplant Patients Entecavell ODT - Hepatitis B Virus, Liver Transplant | Phase 2 | Not yet recruiting | Jongman Kim | 82 | 2026-12-01 | 2026-10-28 |
| A Study to Compare Blood Levels of Bepirovirsen and Safety Using Different Methods of Injecting in Healthy Adult Participants Bepirovirsen - Hepatitis B | Phase 1 | Not yet recruiting | GlaxoSmithKline | 98 | 2026-11-03 | 2026-10-29 |
| HIV/HBV/HCV Triple Screening in Primary Care electronic medical record alert linked to orders - HIV, HBV (Hepatitis B Virus) | Not applicable | Recruiting | University of Texas Southwestern Medical Center | 50 | 2026-11-01 | 2026-10-29 |
| A Study of Sequential Therapy With AHB-137 Injection Followed by TVAX-008 Injection in Participants Living With Chronic Hepatitis B (CHB) AHB-137, Placebo, TVAX-008 - Chronic Hepatitis B | Phase 1 / Phase 2 | Not yet recruiting | Ausper Biopharma Co., Ltd. | 105 | 2026-10-31 | 2026-10-19 |
| A Study of Sequential Therapy With AHB-137 Injection Followed by TVAX-008 Injection in Participants Living With Chronic Hepatitis B (CHB) AHB-137, TVAX-008, Placebo - Chronic Hepatitis B | Phase 1 / Phase 2 | Not yet recruiting | Grand Theravac Life Sciences (Hangzhou) Co., Ltd. | 105 | 2026-10-31 | 2026-10-27 |
| Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Characteristics of ACT500 in Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease Complicated With Chronic Hepatitis B ACT500 Tablets, ACT500 Placebo Tablets - Metabolic Dysfunction-associated Steatotic Liver Disease, Chronic Hepatitis b | Phase 1 | Not yet recruiting | Xiamen Amoytop Biotech Co., Ltd. | 24 | 2026-10-30 | 2026-09-14 |
| A Clinical Study of AHB-121 in Healthy Participants and Chronic Hepatitis B (CHB) Participants AHB-121, Placebo - Chronic Hepatitis B Virus | Phase 1 | Not yet recruiting | Ausper Biopharma Co., Ltd. | 110 | 2026-10-28 | 2026-10-21 |
| Wearable Patch Ultrasound Probe for Diagnosis of Liver Stiffness Wearable Patch-Type Ultrasound Probe, Transient Elastography (FibroScan) - Liver Fibrosis, Liver Cirrhosis | Not yet recruiting | Second Affiliated Hospital of Xi'an Jiaotong University | 150 | 2026-10-01 | 2026-07-21 | |
| Study Interchangeability Hep-B Vaccine Administered at Birth Dose In-house Hepatitis B Vaccine, Registered Hepatitis B Vaccine - Vaccination Adverse Event, Immunogenicity, Vaccine | Phase 3 | Not yet recruiting | PT Bio Farma | 270 | 2026-10-01 | 2026-10-02 |
| Study of BK1803 in Healthy Infants BK1803, GOBIK Aqueous Suspension Syringes, Bimmugen® Injection - Pertussis, Diphtheria | Phase 3 | Not yet recruiting | Tanabe Pharma Corporation | 344 | 2026-10-01 | 2026-08-28 |
| Phase Ia/Ib Trial of SCTA02A Injection in Healthy Adults and Patients With Chronic Hepatitis B SCTA02A, Placebo - Hepatitis B | Phase 1 | Not yet recruiting | Sinocelltech Ltd. | 60 | 2026-10-01 | 2026-10-29 |
| Prospective Evaluation of Hepatocellular Carcinoma Surveillance in At-Risk Patients (Screening HCC) Hepatocellular Carcinoma, Liver Cirrhosis | Not yet recruiting | D'Or Institute for Research and Education | 300 | 2026-09-15 | 2026-08-14 | |
| Strengthening, Guidance, Health, Empowerment Self-sampling for six sexually transmitted infections - HIV Infection, Syphilis | Not applicable | Not yet recruiting | University Hospital, Montpellier | 200 | 2026-09-01 | 2026-08-26 |
| A Trial to Evaluate the Efficacy and Safety of WGc0201 in Patients With Chronic Hepatitis B Virus Infection WGc0201 - Chronic Hepatitis B Virus (Hbv) | Phase 1 | Recruiting | Jiyan Liu | 9 | 2026-09-01 | 2026-07-01 |
| Hepatitis B Infection Surveillance Chronic Hepatitis B Infection | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 1360 | 2026-09-01 | 2026-07-27 | |
| Clinical Trial of TQA3605 Tablet in Combination With Nucleos(t)Ide Analogues(NAs) Versus NAs Alone for the Treatment of Patients With Chronic Hepatitis B Virus Infection Who Have Undergone Treatment and Exhibit Low Viral Load or Poor Response TQA3605 tablets Placebo, TQA3605 tablets, Entecavir dispersible tablets - Chronic Hepatitis B | Phase 3 | Not yet recruiting | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 930 | 2026-09-01 | 2026-10-02 |
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Hepatitis B, Chronic (863) · Hepatitis C (109) · Tetanus (105) · Diphtheria (101) · Haemophilus Infections (82) · Carcinoma, Hepatocellular (81) · Liver Cirrhosis (72) · Whooping Cough (72) · Poliomyelitis (68) · HIV Infections (66) · Hepatitis (58) · Fibrosis (53) · Liver Diseases (32) · Acquired Immunodeficiency Syndrome (30)
Hepadnaviridae Infections (1702) · Blood-Borne Infections (1700) · Digestive System Diseases (1698) · DNA Virus Infections (1696) · Hepatitis, Viral, Human (1694) · Communicable Diseases (1693) · Infections (1687) · Virus Diseases (1682) · Liver Diseases (1670) · Hepatitis (1644) · Pathological Conditions, Signs and Symptoms (979) · Pathologic Processes (973) · Disease Attributes (908) · Chronic Disease (884) · Hepatitis, Chronic (855)
entecavir (198) · Tenofovir (166) · peginterferon alfa-2a (110) · Hepatitis B Vaccines (75) · Lamivudine (64) · tenofovir alafenamide (61) · adefovir dipivoxil (54) · Telbivudine (51) · Engerix-B (49) · adefovir (37) · diphtheria-tetanus-acellular pertussis-inactivated poliovirus-Haemophilus influenzae b conjugate-hepatitis B vaccine (25) · peginterferon alfa-2b (24) · clevudine (21) · Blood Specimen Collection (20) · hepatitis B hyperimmune globulin (18)
GlaxoSmithKline (159) · Hoffmann-La Roche (47) · Gilead Sciences (44) · Third Affiliated Hospital, Sun Yat-Sen University (39) · Bristol-Myers Squibb (35) · National Taiwan University Hospital (30) · Beijing Ditan Hospital (28) · Sanofi Pasteur, a Sanofi Company (28) · Nanfang Hospital, Southern Medical University (25) · Merck Sharp & Dohme LLC (19) · Assembly Biosciences (17) · Bukwang Pharmaceutical (17) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (17) · National Institute of Allergy and Infectious Diseases (NIAID) (16) · The University of Hong Kong (16)
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Liang Peng, Doctor (13) · Marc G Ghany, M.D. (7) · Guiqiang Wang (6) · Jinlin Hou (6) · Junqi Niu (6) · Hong Ren, MM (5) · Hong You, Doctor (5)
PMID 28427875, PMID 19052126, PMID 24915612, PMID 28404091, PMID 28404092, PMID 29405329, PMID 33460002, PMID 35599306, PMID 15470215, PMID 19187608, PMID 21182232, PMID 22436845, PMID 23046671, PMID 23518903, PMID 25987775, PMID 27658343, PMID 32710245, PMID 35941076, PMID 42550463, PMID 15014185, PMID 16391218, PMID 16525137, PMID 16525138, PMID 17716936, PMID 18094378, PMID 19729084, PMID 20009522, PMID 20049753, PMID 20091678, PMID 20657177, PMID 20955704, PMID 21366801, PMID 22045673, PMID 22508412, PMID 22777097, PMID 23234725, PMID 23364953, PMID 23732904, PMID 23939953, PMID 24954675, PMID 25179493, PMID 25277773, PMID 25348661, PMID 25532501, PMID 25788199, PMID 27257978, PMID 28215615, PMID 28340322, PMID 29289383, PMID 29696665
2014 (10), 2016 (9), 2019 (9), 2009 (7), 2015 (7), 2017 (7), U01DK082864 (7), 2023 (5), U01DK082843 (5), U01DK082871 (5), U01DK082874 (5), U01DK082944 (5), UL1TR000004 (5), 2018 (3), M01RR000040 (3)