18 completed, 7 unknown, 3 recruiting, 1 not yet recruiting. 30 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 30 | Completed 18, Unknown 7, Recruiting 3, Not yet recruiting 1, Terminated 1 |
Follow Cerebral Infarction: new trials by email Literature Review of Cerebral Infarction trials Research Report on Cerebral Infarction
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Early Low-dose ASpirin Use After Intravenous Thrombolysis for Acute Ischemic Cerebral Infarction（ELASTIC） Aspirin (Early, 2h), Aspirin (Standard, 24h) - Cerebral Infarction, Thrombolysis | Phase 4 | Not yet recruiting | Beijing Chao Yang Hospital | 210 | 2026-05-01 | 2026-05-08 |
| Mexidol® Safety and Efficacy in Treatment of Hyperacute and Acute Ischemic Stroke Mexidol, Glycine - Ischemic Stroke | Phase 4 | Recruiting | Pharmasoft | 120 | 2025-11-04 | 2026-05-13 |
| The Effect and Safety of Combined Anti-platelet Treatment in Acute Ischemic Stroke Due to Large Artery Atherosclerosis Aspirin, Clopidogrel, Cilostazol - Cerebral Infarction, Stenosis Artery | Phase 4 | Recruiting | Asan Medical Center | 2340 | 2025-07-10 | 2026-03-27 |
| Stroke Prevention In Ischemic Stroke With Covert Atrial Fibrillation Apixaban, Aspirin - Stroke, Ischemic Stroke | Phase 4 | Recruiting | Assistance Publique - Hôpitaux de Paris | 1148 | 2025-06-18 | 2026-06-05 |
| For Patients With Ischemic Stroke, Clinically Study the Effectiveness and Safety of Butylphthalide. Butylphthalide - Stroke, Cerebral Infarction | Phase 4 | Unknown | Qianfoshan Hospital | 300 | 2022-05-07 | 2024-04-09 |
| Study on the Relationship Between Asymmetric Vascular Sign of Cortex and Prognosis in Massive Cerebral Infarction sodium aescinate - Cerebral Infarction, Cerebral Edema | Phase 4 | Unknown | The Second Hospital of Hebei Medical University | 150 | 2020-01-09 | 2020-01-30 |
| Study of Collateral Circulation in Patients With Symptomatic Intracranial Anterior Circulation Occlusion Butylphthalide Soft Capsules - Collateral Circulation, Large-artery Occlusion | Phase 4 | Unknown | The Second Hospital of Hebei Medical University | 500 | 2019-05-05 | 2019-09-16 |
| The Effect of Trazodone on the Severity of Obstructive Sleep Apnea in Insomnic Stroke Patients With Depression Trazodone, Placebo oral tablet - Sleep Apnea Syndromes, Cerebral Infarction | Phase 4 | Completed | Chang Gung Memorial Hospital | 22 | 2019-02-01 | 2020-04-06 |
| Early Rivaroxaban for Acute Ischemic Stroke or TIA Patients With Atrial Fibrillation Rivaroxaban - Cerebral Infarction, TIA | Phase 4 | Completed | General Hospital of Shenyang Military Region | 400 | 2018-11-20 | 2025-08-21 |
| A Phase 4 Clinical Study to Investigate the Efficacy and Safety of Naloxone HCI IV in Patients With Stroke Naloxone hydrochloride 5.0mg/5ml, Sodium Chloride 45mg/5ml - Stroke, Acute | Phase 4 | Completed | Samjin Pharmaceutical Co., Ltd. | 446 | 2018-08-07 | 2023-08-14 |
| Effect of Rosuvastatin on Prognosis of Clinical Response in Acute Ischemic Stroke Patients(REPAIRS) Rosuvastatin - Infarction, Anterior Cerebral Artery | Phase 4 | Unknown | Second Affiliated Hospital of Soochow University | 456 | 2015-09-01 | 2015-06-29 |
| The Study to Reevaluate the Safety and Efficacy of Human Urinary Kallikrein kallikrein - Cerebral Infarction | Phase 4 | Unknown | Techpool Bio-Pharma Co., Ltd. | 2186 | 2015-08-01 | 2018-01-17 |
| The Dynamic Effect of Non-cytochrome P450 Isoenzyme 3A4（CYP3A4）-Metabolized and Cytochrome P450 Isoenzyme 3A4（CYP3A4）-Metabolized Statins on Clopidogrel Resistance in Patients With Cerebral Infarction atorvastatin and clopidogrel, rosuvastatin and clopidogrel - Cerebral Infarction, Clopidogrel,Poor Metabolism of (Disorder) | Phase 4 | Unknown | The Third Affiliated Hospital of Guangzhou Medical University | 160 | 2015-03-01 | 2015-06-16 |
| Nimodipine for Treating Acute Massive Cerebral Infarction Nimodipine, Saline + citicoline - Cerebral Infarction | Phase 4 | Completed | Fengtian Hospital | 72 | 2014-10-01 | 2018-05-01 |
| Efficacy of Pain Treatment on Depression in Patients With Dementia Paracetamol, Buprenorphine, Paracetamol placebo - Depression, Pain | Phase 4 | Completed | University of Bergen | 163 | 2014-08-01 | 2017-04-04 |
| Thrombectomy Under Reopro Versus Alteplase to Treat Stoke abciximab IV and thrombectomy, alteplase 0.9mg/kg (10% by IV bolus following by 90% by 1 hour IV drip) - Infarction, Middle Cerebral Artery | Phase 4 | Terminated | SOS Attaque Cérébrale | 40 | 2013-09-01 | 2014-04-25 |
| The Effect of Erigeron Injection on Acute Cerebral Infarction Serum VEGF, MMP-9 and EPC Levels Erigeron Injection, placebo - Cerebral Infarction | Phase 4 | Unknown | Guangzhou University of Traditional Chinese Medicine | 60 | 2013-08-01 | 2013-08-21 |
| Comparison of Triflusal and Clopidogrel in Secondary Prevention of Stroke Based on the Genotyping Triflusal, Clopidogrel - Cerebral Infarction | Phase 4 | Completed | Gangnam Severance Hospital | 795 | 2010-03-01 | 2015-03-17 |
| Platelet Hyperreactivity to Aspirin and Stroke Aspirin (platelet sensitive versus platelet hyperreactivity) - Stroke, Cerebral Infarction | Phase 4 | Completed | University of Sao Paulo | 203 | 2009-07-01 | 2013-06-24 |
| Overcome Biochemical Aspirin Resistance Through Cilostazol Combination Cilostazol, placebo - Cerebral Infarction | Phase 4 | Completed | Asan Medical Center | 244 | 2007-03-01 | 2010-01-18 |
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Stroke (9) · Ischemic Stroke (5) · Atherosclerosis (3) · Brain Ischemia (2) · Vascular Diseases (2) · Acute Coronary Syndrome (1) · Agnosia (1) · Alzheimer Disease (1) · Atrial Fibrillation (1) · Brain Edema (1) · Brain Infarction (1) · Cardiovascular Diseases (1) · Carotid Artery Diseases (1) · Carotid Stenosis (1)
Brain Diseases (30) · Cerebrovascular Disorders (30) · Infarction (30) · Necrosis (30) · Pathologic Processes (30) · Pathological Conditions, Signs and Symptoms (30) · Brain Infarction (29) · Cardiovascular Diseases (29) · Central Nervous System Diseases (29) · Ischemia (29) · Nervous System Diseases (29) · Brain Ischemia (28) · Vascular Diseases (28) · Stroke (21) · Arterial Occlusive Diseases (4)
Aspirin (8) · Cilostazol (6) · Clopidogrel (5) · Rivaroxaban (2) · Rosuvastatin Calcium (2) · Sodium Chloride (2) · Tissue Plasminogen Activator (2) · 3-n-butylphthalide (1) · Acetaminophen (1) · Atorvastatin (1) · Buprenorphine (1) · Cytidine Diphosphate Choline (1) · Dabigatran (1) · Edaravone (1) · Glycine (1)
Asan Medical Center (3) · Guangzhou University of Traditional Chinese Medicine (2) · The Second Hospital of Hebei Medical University (2) · Abbott Medical Devices (1) · Assistance Publique - Hôpitaux de Paris (1) · Beijing Chao Yang Hospital (1) · Chang Gung Memorial Hospital (1) · Fengtian Hospital (1) · Gangnam Severance Hospital (1) · General Hospital of Shenyang Military Region (1) · Inje University (1) · Korea Otsuka Pharmaceutical Co., Ltd. (1) · National Institute of Neurological Disorders and Stroke (NINDS) (1) · Otsuka Pharmaceutical Co., Ltd. (1) · Pharmasoft (1)
China (8) · South Korea (7) · Japan (3) · France (2) · Brazil (1) · Hong Kong (1) · Norway (1) · Philippines (1) · Russia (1) · Taiwan (1) · Thailand (1) · United States (1)
Xiaoyun Liu, Prf. (2) · Ane Erdal, PhD candidate (1) · Chun-Feng Liu, Ph.D,M.D. (1) · Don E Schwarten, MD (1) · Dong Keun Hyun, M.D.,Ph.D (1) · Elisabeth Flo, PhD (1) · Herlon S Martins, MD (1) · Huisheng Chen, Doctor (1) · Irineu T Velasco, PHD (1) · Jae Hyeon Park, MD, PhD (1)
PMID 15837243, PMID 16386660, PMID 19321945, PMID 19829090, PMID 20075341, PMID 20456839, PMID 20833591, PMID 21030700, PMID 21613787, PMID 21799173, PMID 22539545, PMID 22910894, PMID 23128968, PMID 24315720, PMID 24957314, PMID 26763917, PMID 28265861, PMID 29487556, PMID 29725986, PMID 33189083, PMID 33625584, PMID 40207533