14 completed, 6 unknown, 4 not yet recruiting, 4 withdrawn. 8 Phase 2, 7 Not applicable, 5 Phase 1, 2 Early Phase 1, 2 Phase 3.
Follow Cerebral Edema: new trials by email Literature Review of Cerebral Edema trials Research Report on Cerebral Edema
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| TENS of Auricular Vagal Nerve for Radiation Necrosis Transcutaneous auricular vagal nerve stimulation (taVNS), Sham - Radiation Necrosis, Cerebral Edema | Not applicable | Not yet recruiting | Virginia Commonwealth University | 40 | 2026-11-30 | 2026-09-04 |
| ONSD Trajectory in Rebound ICH Optic Nerve Sheath Diameter Ultrasonography - Traumatic Brain Injury, Rebound Intracranial Hypertension | Not yet recruiting | Benha University | 100 | 2026-09-01 | 2026-07-23 | |
| A Trial of Adacolumn on Cerebral Edema After Anterior Circulation Ischemic Stroke Adacolumn®, Standard Reperfusion Therapy, Standard Medical Management - Cerebral Edema, Ischemic Stroke, Acute | Not applicable | Not yet recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 10 | 2026-08-10 | 2026-08-07 |
| High-volume Versus Standard Volume Plasma Exchange in Patients With Acute Liver Failure With Cerebral Edema High Volume Therapeutic Plasma Exchange, Standard volume therapeutic plasma exchange - Acute Liver Failure, Cerebral Edema | Not applicable | Not yet recruiting | Institute of Liver and Biliary Sciences, India | 60 | 2025-12-01 | 2025-09-19 |
| Early Prophylactic Decompressive Hemicraniectomy Following Endovascular Therapy in Large Hemispheric Infarct Trial Early prophylactic decompressive hemicraniectomy - Stroke, Ischemic, Cerebral Edema | Not applicable | Recruiting | Xuanwu Hospital, Beijing | 380 | 2025-07-19 | 2026-01-26 |
| Safety and Efficacy of ABX-101 in Participants Aged 18 to 50 Years of Age With Moderate to Severe Traumatic Brain Injury ABX-101 1mg, ABX-101 2mg - Traumatic Brain Injury, Cerebral Edema | Phase 2 | Unknown | Abalonex, LLC | 45 | 2023-12-01 | 2023-10-23 |
| International Multi-center Retrospective Study of Patients With Serum Sodium ≤110 mmol/L to Determine the Relationship Between Osmotic Demyelination Syndrome (ODS) and Rapid Correction of Hyponatremia Hypertonic 3% saline - Hyponatremia Symptomatic, Osmotic Demyelination Syndrome | Enrolling by invitation | Rochester General Hospital | 800 | 2023-11-01 | 2026-08-26 | |
| AI Assisted Reader Evaluation in Acute Computed Tomography (CT) Head Interpretation Ground truthing, Reading - Intracranial Hemorrhages, Acute Ischemic Stroke | Completed | Oxford University Hospitals NHS Trust | 33 | 2023-06-01 | 2025-11-24 | |
| Clinical Significance of DKK2 Protein in Cerebral Ischemia-reperfusion Injury enzyme-linked immunosorbent assay(ELISA) - Ischemic Stroke, Acute, Ischemia-reperfusion Injury | Unknown | Nanfang Hospital, Southern Medical University | 108 | 2022-09-01 | 2024-03-25 | |
| Inflammation and Coagulation Factors for Predicting Cerebral Edema After SAH Inflammatory factors and coagulation factors level in cerebrospinal fluid after subarachnoid hemorrhage - Inflammation, Coagulation and Hemorrhagic Disorders | Unknown | Second Affiliated Hospital, Zhejiang University, School of Medicine | 80 | 2022-08-01 | 2023-08-24 | |
| Study on Data Acquisition and Image Characteristics of Brain Multifrequency EIT in Healthy People and Patients With Brain Diseases multifrequency EIT-based for detecting intracranial abnormalities - Cerebral Hemorrhage, Cerebral Ischemia | Completed | Jieshi Ma | 24 | 2022-06-01 | 2023-04-03 | |
| The Tolerability, Safety, and PK Characteristics of SIM1910-09 in Healthy Chinese Volunteers SIM1910-09, Placebo - Acute Ischemic Stroke, Cerebral Edema | Phase 1 | Completed | Jiangsu Simcere Pharmaceutical Co., Ltd. | 68 | 2021-12-06 | 2023-11-30 |
| Wet and Dry Biomarkers to Predict Secondary Injury in Stroke: From Bench to Bedside - The NIMBLE Study Acute Ischemic Stroke, Reperfusion Injury | Completed | University of Florence | 213 | 2021-04-17 | 2026-02-20 | |
| Coagulation Activation by Hyperosmolar Agents in Intracranial Hypertension Mannitol, Hypertonic saline solution - Intracranial Hypertension, Cerebral Edema | Withdrawn | Neuromed IRCCS | 2020-12-03 | 2020-11-19 | ||
| Fingolimod as a Treatment of Cerebral Edema After Intracerebral Hemorrhage Fingolimod, Placebo, Open-label Fingolimod - Intracerebral Hemorrhage, Cerebral Edema | Early Phase 1 | Completed | Wake Forest University Health Sciences | 28 | 2020-08-07 | 2025-01-23 |
| Trial of Dexamethasone for Traumatic Brain Injured Patients With Brain Contusions and Pericontusional Edema Dexamethasone Oral, Placebo oral tablet - Traumatic Brain Injury, Cerebral Edema | Phase 3 | Terminated | Jon Pérez Bárcena | 600 | 2020-07-24 | 2026-02-06 |
| Study on the Relationship Between Asymmetric Vascular Sign of Cortex and Prognosis in Massive Cerebral Infarction sodium aescinate - Cerebral Infarction, Cerebral Edema | Phase 4 | Unknown | The Second Hospital of Hebei Medical University | 150 | 2020-01-09 | 2020-01-30 |
| Conventional Hemodialysis Versus Post-Dilution Hemofiltration in Incident RRT Hemofiltration - Dialysis; Complications, Hemodialysis Complication | Not applicable | Completed | Instituto Nacional de Cardiologia Ignacio Chavez | 24 | 2020-01-06 | 2021-09-29 |
| Antisecretory Factor in Primary Glioblastoma 1 Salovum - Glioblastoma, Cerebral Edema | Phase 1 / Phase 2 | Completed | Peter Siesjö | 8 | 2019-09-01 | 2021-04-28 |
| Noninvasive Monitoring of Cerebral Blood Flow Autoregulation Intracranial Pressure Increase, Cerebral Edema | Completed | Ochsner Health System | 14 | 2018-04-18 | 2021-12-27 |
Showing 20 of 34. Sign in to see all of them.
Brain Edema (34) · Ischemic Stroke (8) · Stroke (6) · Brain Injuries, Traumatic (5) · Brain Injuries (4) · Cerebral Hemorrhage (4) · Reperfusion Injury (3) · Cerebral Infarction (2) · Disease Models, Animal (2) · Glioblastoma (2) · Intracranial Hemorrhages (2) · Intracranial Hypertension (2) · Wounds and Injuries (2) · Altitude Sickness (1) · Astrocytoma (1)
Brain Diseases (33) · Central Nervous System Diseases (33) · Nervous System Diseases (33) · Cardiovascular Diseases (17) · Vascular Diseases (17) · Cerebrovascular Disorders (15) · Pathological Conditions, Signs and Symptoms (14) · Pathologic Processes (13) · Stroke (8) · Trauma, Nervous System (7) · Craniocerebral Trauma (6) · Hemorrhage (6) · Wounds and Injuries (5) · Brain Ischemia (4) · Intracranial Hemorrhages (4)
Saline Solution, Hypertonic (4) · Mannitol (3) · Sodium Chloride (3) · Acetazolamide (2) · conivaptan (2) · AER-271 (1) · Deamino Arginine Vasopressin (1) · Dexamethasone (1) · Dextromethorphan (1) · Diphenhydramine (1) · Famotidine (1) · Fingolimod Hydrochloride (1) · Frankincense (1) · Glucose (1) · Glyburide (1)
Second Affiliated Hospital, Zhejiang University, School of Medicine (2) · University of Florida (2) · Xuanwu Hospital, Beijing (2) · Abalonex, LLC (1) · Ali Altunkaya (1) · Benha University (1) · Colin Grissom (1) · Cukurova University (1) · Institute of Liver and Biliary Sciences, India (1) · Instituto Nacional de Cardiologia Ignacio Chavez (1) · Istituto di Neuroscienze Consiglio Nazionale delle Ricerche (1) · Jesse Corry (1) · Jiangsu Simcere Pharmaceutical Co., Ltd. (1) · Jieshi Ma (1) · Jon Pérez Bárcena (1)
United States (12) · China (8) · Italy (2) · Egypt (1) · India (1) · Israel (1) · Mexico (1) · Spain (1) · Sweden (1) · Turkey (Türkiye) (1) · United Kingdom (1)
Alex Novak, MSc (1) · Anna Letizia Allegra Mascaro, PhD (1) · Benedetta Piccardi, MD, PhD (1) · Brian P Walcott, MD (1) · Brian V Nahed, MD (1) · Colin K Grissom, MD (1) · Cristina Sarti, MD (1) · Fulvio Aloj, MD (1) · Glen Stevens, DO, PhD (1) · Jesse J Corry, MD (1) · Licia Iacoviello, MD, PhD (1) · Louis Cannizzaro, MD (1) · Marzia Baldereschi, MD (1) · Michael F Waters, MD (1) · Nathan Kuppermann, MD, MPH (1)
PMID 22943271, PMID 32253717, PMID 33546038, PMID 36803465, PMID 37899042, PMID 38346874, PMID 38775299, PMID 42712312
2019 (1), R21CA107277 (1), U01HD062417 (1), UL1TR001420 (1)