Inflammation and Coagulation Factors for Predicting Cerebral Edema After SAH

• Inflammatory factors and coagulation factors level in cerebrospinal fluid after subarachnoid hemorrhage (Diagnostic test): Inflammatory factors and coagulation factors level in cerebrospinal fluid will be tested by ELISA kits.

Primary outcomes

• Cerebral edema after subarachnoid hemorrhage [At 3 and 7days after SAH onset]: Cerebral edema after subarachnoid hemorrhage will be determined by the SEBES score. SEBES 0-2 is mild edema; SEBES 3-4 is severe edema.
• Outcome at 3 months after subarachnoid hemorrhage [3 months after subarachnoid hemorrhage]: Outcome will be determined by the modified Rankin Score (mRS). mRS 0-2 is favorable outcome; mRS3-5 is poor outcome.

Sex: All, ages: 20 Years to 80 Years

Inclusion Criteria:

* Subarachnoid hemorrhage patients admitted to our neurosurgery department with modified Fisher Scale 3-4, with a confirmed radiographic diagnosis.

Exclusion Criteria:

* Angiogram-negative patients, patients with a history of trauma or previous brain injury (stroke, hemorrhage, surgery et al. which left associated chronic changes on CT), arteriovenous malformation, radiological data lost, accompany with serious comorbidities before subarachnoid hemorrhage onset (such as coagulation defects, uncontrollable hypertension, and arrhythmia et.al.), initial radiological data performed more than 3 days after SAH onset