13 completed, 8 unknown, 6 terminated, 3 active not recruiting. 17 Not applicable, 5 Phase 1, 4 Phase 2, 2 Phase 3, 1 Phase 4.
Follow Cartilage Injury: new trials by email Literature Review of Cartilage Injury trials Research Report on Cartilage Injury
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Emerging Indications for Hyperbaric Oxygen Treatment Hyperbaric oxygen treatment (HBOT), 100% Oxygen - Post-COVID-19 Condition, Ulcerative Colitis | Phase 4 | Not yet recruiting | Jay C. Buckey Jr. | 100 | 2026-11-01 | 2026-09-09 |
| Long-term Outcome Evaluation of Patients Undergoing Autologous Chondrocyte Transplantation Delivered on Biomaterial Cartilage Injury, Cartilage Disease | Not yet recruiting | Istituto Ortopedico Rizzoli | 200 | 2026-09-01 | 2026-07-01 | |
| Tissue Engineered Cartilage to Repairing Articular Cartilage Defects Tissue engineered cartilage - Cartilage Injury, OA Knee | Not applicable | Recruiting | The First Affiliated Hospital of Xinxiang Medical College | 30 | 2026-04-20 | 2026-05-04 |
| The Hyalex First-in-Human Study Surgical (Hyalex Cartilage Knee Implant) - Cartilage Injury | Not applicable | Active not recruiting | Hyalex Orthopaedics, Inc. | 15 | 2024-03-07 | 2026-10-06 |
| CAsting and REhabilitation Versus Supervised Neglect for Osteochondral Lesions of the Talus in the Pediatric Population Casting and supervised rehabilitation - Cartilage Injury, Orthopedic Disorder | Not applicable | Not yet recruiting | Tristan Buck | 76 | 2024-02-01 | 2024-01-24 |
| Effect of Platelet-rich Plasma (PRP) Injection on Knee Osteoarthritis Sodium hyaluronate injection - Platelets-rich Plasma, Osteoarthritis Knees Both | Not applicable | Recruiting | Xijing Hospital | 300 | 2023-09-01 | 2026-07-30 |
| Biomaterials and Mesenchymal Stem/Stromal Cells in the Treatment of Knee Articular Surface Lesions Biomaterials augmented with mesenchymal stem/stromal cells - Knee Injuries, Cartilage Injury | Completed | University Medical Centre Ljubljana | 90 | 2022-09-01 | 2023-11-30 | |
| Synovial Tissue and Fat Pad Stromal Vascular Fraction Bioengineering in Patients With Knee Articular Cartilage Injury Synovial Tissue and Fat Pad Stromal Vascular Fraction - Cell- and Tissue-Based Therapy, Cartilage Injury | Phase 1 / Phase 2 | Unknown | University of Sao Paulo General Hospital | 10 | 2022-04-01 | 2021-11-15 |
| PROPER Trial of Pain and Inflammation After Knee Arthroscopy Ceftriaxone, Placebo - Meniscus Tear, Meniscus Lesion | Phase 2 | Terminated | Austin V Stone | 5 | 2021-12-28 | 2023-09-05 |
| Treatment of Cartilage Defects With Peripheral Blood Stem Cells autologous peripheral blood mesenchymal stem cell, Microfracture, Microfracture + collagen membrane - Cartilage Injury | Phase 1 | Unknown | Peking University Third Hospital | 252 | 2021-08-01 | 2021-07-08 |
| Clinical and Comparative Evaluation of the Treatment Results of Arthroscopic Reconstruction of Cartilage Defects in the Knee Joint With the Use of Autogenous Cartilage Graft With PRP GF (Platelet-rich Plasma With Growth Factors) Arthroscopic reconstruction of cartilage defects in the knee joint with the use of autogenous cartilage transplant with PRP GF (platelet plasma with growth factor), Arthroscopic reconstruction of the cartilage defects of the knee joint using the microfracture method - Cartilage Damage, Cartilage Injury | Not applicable | Unknown | eMKa MED Medical Center | 60 | 2021-06-22 | 2022-04-14 |
| The Impact of Covid-19 on Patients Waiting for Knee Surgery Survey - Osteoarthritis, Knee, Osteochondral Defect | Unknown | University of Manchester | 300 | 2021-05-27 | 2021-11-18 | |
| Assessment Micro-anatomy of the Menisci and Cartilage After Isolated Acute ACL Injury With MRI at 7T Ultrahigh Field MRI at 7T - Meniscus Lesion, Cartilage Injury | Not applicable | Terminated | Balgrist University Hospital | 23 | 2021-04-22 | 2024-01-18 |
| Clinical Study of Chondro-Gide® for Large Chondral Lesions in the Knee Microfracture, Microfracture plus placement of Chondro-Gide® ACC - Knee Injuries, Cartilage Injury | Not applicable | Terminated | Geistlich Pharma AG | 82 | 2020-08-26 | 2026-02-13 |
| ProChondrix® CR Articular Cartilage Restoration Evaluation (PACE) Registry Articular cartilage repair - Cartilage Injury, Cartilage Damage | Terminated | AlloSource | 48 | 2020-01-06 | 2025-11-21 | |
| 7T MRI to Evaluate Cartilage Defects in the Knee 7 Tesla Magnetic Resonance Imaging Test - Cartilage Injury, Knee Injuries | Completed | The Methodist Hospital Research Institute | 112 | 2019-10-07 | 2025-02-07 | |
| The Treatment of Cartilaginous Lesions and Concomitant Anterior Cruciate Ligament Reconstruction Nanofractures, no treatment cartilaginous lesions - Cruciate Ligament Rupture, Cartilage Injury | Not applicable | Terminated | Istituto Ortopedico Rizzoli | 4 | 2019-07-25 | 2026-05-22 |
| Prospective Evaluation of ProChondrix CR for Repair of Articular Cartilage Defects on Femoral Condyle and Patella Cryopreserved Osteochondral Allograft - Cartilage Injury, Cartilage Damage | Active not recruiting | AlloSource | 34 | 2019-03-18 | 2025-11-25 | |
| Impact of Mesenchymal Stem Cells in Knee Osteoarthritis Autologous Mesenchymal Stem Cells - Musculoskeletal Pain, Knee Osteoarthritis | Phase 1 | Completed | University Hospitals Cleveland Medical Center | 16 | 2018-10-01 | 2026-10-05 |
| Clinical Study of Decalcification Bone Scaffold for Cartilage Lesions of the Knee decalcification bone scaffold, microfracture - Cartilage Injury | Not applicable | Unknown | Peking University Third Hospital | 60 | 2018-09-11 | 2020-07-02 |
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Knee Injuries (8) · Fractures, Stress (5) · Osteoarthritis, Knee (5) · Anterior Cruciate Ligament Injuries (3) · Osteoarthritis (3) · Cartilage Diseases (2) · Osteochondritis Dissecans (2) · Osteonecrosis (2) · Wounds and Injuries (2) · COVID-19 (1) · Calciphylaxis (1) · Colitis, Ulcerative (1) · Craniocerebral Trauma (1) · Crohn Disease (1) · Disease (1)
Wounds and Injuries (13) · Musculoskeletal Diseases (12) · Leg Injuries (11) · Arthritis (8) · Joint Diseases (8) · Rheumatic Diseases (8) · Fractures, Bone (5) · Osteoarthritis (5) · Pathological Conditions, Signs and Symptoms (4) · Bone Diseases (3) · Knee Injuries (3) · Pathologic Processes (3) · Skin and Connective Tissue Diseases (3) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (2) · Connective Tissue Diseases (2)
Arthroplasty, Subchondral (6) · Sodium Chloride (2) · Ceftriaxone (1) · Hyaluronic Acid (1) · Intercellular Signaling Peptides and Proteins (1) · Lidocaine (1) · Oxygen (1) · Saline Solution (1) · Surgical Procedures, Operative (1) · Surveys and Questionnaires (1)
Peking University Third Hospital (3) · AlloSource (2) · Geistlich Pharma AG (2) · Istituto Ortopedico Rizzoli (2) · University Hospital, Akershus (2) · Austin V Stone (1) · Balgrist University Hospital (1) · BioPoly LLC (1) · Chinese PLA General Hospital (1) · Hadassah Medical Organization (1) · Hyalex Orthopaedics, Inc. (1) · Jay C. Buckey Jr. (1) · Keele University (1) · Lund University (1) · Medipost Co Ltd. (1)
United States (8) · China (5) · United Kingdom (4) · Norway (3) · Germany (2) · Poland (2) · Canada (1) · Israel (1) · Italy (1) · Netherlands (1) · Slovenia (1) · South Korea (1) · Sweden (1) · Switzerland (1)
Adam Yanke, MD (1) · Alister Hart, MD (1) · Ann Kristin Hansen, MD, PhD (1) · Austin V Stone, MD, PhD (1) · Dennis G McGonagle, MB BcH BAO (1) · Dinesh Nathwani, MD (1) · Fabiana Martinelli (1) · Gunnar Knutsen, MD, PhD (1) · Heidi Hanvold, PT (1) · Hong-chul Lim, MD, PhD (1) · James E Voos, MD (1) · Jan Herman Kuiper, PhD (1) · Jay Buckey (1) · Jia-kuo Yu, Prof. (1) · Kevin Plancher, MD (1)
PMID 33913035, PMID 18523506, PMID 18759314, PMID 21518322, PMID 22314040, PMID 22724879, PMID 23375182, PMID 23730377, PMID 25822648, PMID 26956476, PMID 27422025, PMID 28108777, PMID 30229214, PMID 31555714, PMID 33490296, PMID 38495635, PMID 38630297, PMID 38767159