12 completed, 3 terminated, 2 active not recruiting, 2 recruiting. 23 Phase 3, 5 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 23 | Completed 12, Terminated 3, Active not recruiting 2, Recruiting 2, Unknown 2, Not yet recruiting 1, Withdrawn 1 |
| Phase 2 | 5 | Completed 2, Recruiting 1, Terminated 1, Unknown 1 |
Follow Calcinosis: new trials by email Literature Review of Calcinosis trials Research Report on Calcinosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Ramipril vs. Amlodipine in Pediatric Hemodialysis Patients Ramipril tablet, Amlodipine tablet - Endothelial Dysfunction, End-Stage Renal Disease | Phase 3 | Not yet recruiting | Ain Shams University | 50 | 2026-11-01 | 2026-10-21 |
| The GranStone Trial empagliflozin (Jardiance) 25 mg, Losartan 100 mg - Paraffinoma, Granuloma, Foreign-Body | Phase 2 / Phase 3 | Recruiting | Martin Blomberg Jensen | 100 | 2026-10-20 | 2026-11-10 |
| Efficacy and Safety of Encaleret Compared to Standard of Care in Participants With ADH1 Encaleret, Standard of Care - Autosomal Dominant Hypocalcemia (ADH) | Phase 3 | Active not recruiting | Calcilytix Therapeutics, Inc., a BridgeBio company | 67 | 2023-01-06 | 2026-07-29 |
| Colchicine and Inflammation in Aortic Stenosis Colchicine, Placebo - Aortic Valve Disease, Aortic Valve Stenosis | Phase 3 | Active not recruiting | Radboud University Medical Center | 150 | 2022-12-22 | 2026-08-27 |
| SGLT2 Inhibitors in Non-Diabetic CKD: Effects on Vascular Calcification and Anemia Dapagliflozin (10Mg Tab) along with standard medical therapy, Placebo - Chronic Kidney Disease, Anemia | Phase 3 | Completed | Mansoura University | 100 | 2022-09-01 | 2026-01-15 |
| Better Evidence and Translation for Calciphylaxis Vitamin K1, Magnesium citrate, Sodium Thiosulfate - Calciphylaxis | Phase 3 | Recruiting | University of Sydney | 350 | 2021-08-26 | 2025-08-13 |
| Phase 3 Study of SNF472 for Calciphylaxis Experimental: SNF472, Placebo Comparator: Placebo, Experimatenl SNF472 (Open-label) - Calciphylaxis, Calcific Uremic Arteriolopathy | Phase 3 | Completed | Sanifit Therapeutics S. A. | 71 | 2020-02-12 | 2024-02-20 |
| Cholecalciferol on Hemodialysis Patients Cholecalciferol, Placebo - Hemodialysis Complication, Vitamin D Deficiency | Phase 2 / Phase 3 | Completed | Ain Shams University | 60 | 2018-07-01 | 2019-01-09 |
| Sodium Thiosulfate for Treatment of Calcinosis Associated With Juvenile and Adult Dermatomyositis Sodium Thiosulfate - Dermatomyositis, Idiopathic Inflammatory Myopathies | Phase 2 / Phase 3 | Completed | National Institute of Environmental Health Sciences (NIEHS) | 15 | 2017-10-05 | 2024-11-26 |
| A Phase 3 Clinical Trial of Intravenous Sodium Thiosulfate in Acute Calciphylaxis Patients Sodium Thiosulfate, Placebo-Normal Saline - Calciphylaxis | Phase 3 | Terminated | Hope Pharmaceuticals | 29 | 2017-05-24 | 2020-05-19 |
| ACTHAR GEL for Sarcoidosis-Associated Calcium Dysregulation: An Open-label Pilot Study ACTHAR Gel (adrenocorticotropic hormone) - Sarcoidosis, Hypercalcemia Due to Sarcoidosis | Phase 2 / Phase 3 | Unknown | Albany Medical College | 10 | 2015-02-01 | 2015-01-26 |
| Double-blind Trial of Sodium Thiosulfate for the Treatment of Pain Associated With Calcific Uremic Arteriolopathy Sodium thiosulfate, Placebo - Calciphylaxis, Calcific Uremic Arteriolopathy | Phase 3 | Withdrawn | American Regent, Inc. | 2015-01-30 | 2025-05-07 | |
| Prevention of the Progression of Coronary Calcification With Use of Spironolactone in Peritoneal Dialysis Patients Spironolactone 25Mg Tablet - Coronary Artery Calcification, Vascular Calcification | Phase 3 | Completed | Professor Fernando Figueira Integral Medicine Institute | 33 | 2014-11-07 | 2017-10-19 |
| Exparel as a Nerve Block for Severe Hand Pain liposomal bupivacaine - CREST Syndrome, Peripheral Vascular Disease | Phase 2 / Phase 3 | Terminated | Jose Soberon, MD | 13 | 2014-11-01 | 2024-05-21 |
| Study to Assess the Efficacy and Safety of Oral Potassium Citrate on the Prevention of Nephrocalcinosis in Extreme Premature Potassium Citrate, Placebo - Nephrocalcinosis | Phase 3 | Unknown | Juan A. Arnaiz | 74 | 2013-01-01 | 2012-12-27 |
| Outcome Study of Lanthanum Carbonate Compared With Calcium Carbonate in Hemodialysis Patients : Landmark Study Lanthanum Carbonate, Calcium Carbonate - Hemodialysis, Hyperphosphatemia | Phase 3 | Completed | Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan | 2309 | 2011-12-24 | 2020-11-30 |
| Dose Defining Study for the Administration of Vitamin K2 Supplements in Hemodialysis Patients Vitamin K2 supplementation - Vascular Calcification | Phase 3 | Completed | Rogier Caluwe | 165 | 2011-05-01 | 2012-08-29 |
| Nicotinamide Versus Sevelamer Hydrochloride on Phosphatemia Control on Chronic Hemodialysed Patients nicotinamide, sevelamer, cinacalcet - Chronic Renal Failure, Hemodialysis | Phase 3 | Terminated | Centre Hospitalier Universitaire, Amiens | 176 | 2010-01-01 | 2016-05-16 |
| Queen's University Investigation of Calcification in Chronic Kidney Disease Bisphosphonate, Placebo - Chronic Kidney Disease | Phase 3 | Completed | Queen's University | 25 | 2008-10-01 | 2015-09-28 |
| Vitamin K2 Supplementation to Activate Matrix Gla Protein (MGP) as Endogenous Inhibitor of Vascular Calcification in Hemodialysis Patients daily supplementation of MK-7 over 6 weeks - CKD 5D, Hemodialysis | Phase 3 | Completed | RWTH Aachen University | 53 | 2008-01-01 | 2011-08-02 |
Showing 20 of 23. Sign in to see all of them.
Vascular Calcification (11) · Nephrocalcinosis (5) · Calciphylaxis (4) · Kidney Failure, Chronic (4) · Inflammation (3) · Nephrolithiasis (3) · Renal Insufficiency, Chronic (3) · Calcium Metabolism Disorders (2) · Dyslipidemias (2) · Hypercalcemia (2) · Hypercalciuria (2) · Metabolic Diseases (2) · Anemia (1) · Aortic Valve Disease (1)
Nutritional and Metabolic Diseases (23) · Calcium Metabolism Disorders (21) · Metabolic Diseases (21) · Pathological Conditions, Signs and Symptoms (12) · Female Urogenital Diseases (11) · Female Urogenital Diseases and Pregnancy Complications (11) · Kidney Diseases (11) · Male Urogenital Diseases (11) · Pathologic Processes (11) · Urogenital Diseases (11) · Urologic Diseases (11) · Chronic Disease (7) · Disease Attributes (7) · Renal Insufficiency (6)
Sodium Chloride (4) · sodium thiosulfate (4) · Tablets (2) · Adrenocorticotropic Hormone (1) · Amlodipine (1) · Atorvastatin (1) · Calcium Carbonate (1) · Cholecalciferol (1) · Cinacalcet (1) · Colchicine (1) · Diphosphonates (1) · Losartan (1) · Niacinamide (1) · Potassium Citrate (1) · Ramipril (1)
Ain Shams University (2) · Albany Medical College (1) · American Regent, Inc. (1) · Calcilytix Therapeutics, Inc., a BridgeBio company (1) · Centre Hospitalier Universitaire, Amiens (1) · Ercan OK (1) · Hope Pharmaceuticals (1) · Jose Soberon, MD (1) · Juan A. Arnaiz (1) · Mansoura University (1) · Martin Blomberg Jensen (1) · National Institute of Environmental Health Sciences (NIEHS) (1) · National Institute on Aging (NIA) (1) · Professor Fernando Figueira Integral Medicine Institute (1) · Queen's University (1)
United States (8) · Canada (3) · Germany (3) · United Kingdom (3) · Australia (2) · Denmark (2) · Egypt (2) · France (2) · Japan (2) · Netherlands (2) · Spain (2) · Belgium (1) · Brazil (1) · Czechia (1) · Italy (1)
Adam I Schiffenbauer, M.D. (1) · Alex Gold, MD (1) · Alex SR Souza, PhD (1) · Aluizio B Carvalho, PhD (1) · An Devriese, MD, PhD (1) · Ana Paula S Gueiros, MD (1) · Bernd Hoppe, Prof. Dr. (1) · Bruno Van Vlem, MD, PhD (1) · Craig Sherman, MD (1) · Dulce E Casarini, PhD (1) · Ercan Ok, MD (1) · Eveline B Calado, MD (1) · Francisco Botet Mussons, MD (1)
PMID 39186385, PMID 40576086, PMID 12935835, PMID 16973975, PMID 18625626, PMID 18689371, PMID 18697901, PMID 19386744, PMID 19776145, PMID 20237066, PMID 20719580, PMID 21628633, PMID 22169620, PMID 22955514, PMID 23719555, PMID 24184249, PMID 33586138, PMID 33594986, PMID 34003226, PMID 39252867, PMID 40659197
R01AG019147 (1), R01HL069272 (1)