13 completed, 3 not yet recruiting, 3 recruiting, 3 terminated. 8 Not applicable, 8 Phase 3, 6 Phase 2, 6 Phase 4, 2 Phase 1.
Follow Potassium Citrate: new trials by email Literature Review of Potassium Citrate trials Research Report on Potassium Citrate
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparing Alkalinizing Agents Efficacy on Stone Risk in Patients on a Metabolically Controlled Diet Potassium citrate, Sodium bicarbonate, Litholyte - Kidney Stone | Early Phase 1 | Not yet recruiting | University of Texas Southwestern Medical Center | 15 | 2026-07-01 | 2026-02-13 |
| Sodium Bicarbonate as an Alternative to Potassium Citrate for Kidney Stones Potassium Citrate, Sodium Bicarbonate - Kidney Stones, Urolithiasis, Hypocitraturia, Nephrolithiasis | Phase 1 / Phase 2 | Not yet recruiting | University of California, Los Angeles | 30 | 2026-02-01 | 2026-02-12 |
| Urine Alkalinization for UTI in Women: RCT potassium citrate, Nitrofurantoin - UTI - Urinary Tract Infection | Not applicable | Not yet recruiting | Assiut University | 50 | 2025-10-15 | 2025-10-02 |
| Impact of Sodium Bicarbonate on 24-hour Urine Parameters in Hypocitriuric and Uric Acid Stone Formers Potassium citrate, Sodium bicarbonate - Uric Acid Stones | Phase 1 | Recruiting | University of California, Irvine | 100 | 2025-05-01 | 2025-06-24 |
| A Randomized Clinical Trial to Evaluate the Effectiveness of Oral Potassium Citrate in Preventing Ureteral Stent Encrustation in Patients Undergoing Ureteroscopy for Uric Acid Kidney Stones Oral Potassium Citrate - Urolithiasis, Stone Ureter | Phase 2 / Phase 3 | Unknown | Zagazig University | 48 | 2024-11-03 | 2025-02-11 |
| Bone in CKD Alkali Response (BICARb Pilot Trial) Potassium Citrate Extended Release Oral Tablet, Placebo, Potassium Citrate and Citric Acid Oral Solution - Chronic Kidney Diseases, Bone Loss | Phase 2 / Phase 3 | Terminated | Albert Einstein College of Medicine | 6 | 2024-08-15 | 2026-07-28 |
| Study Evaluating Patients With Cystinuria ADV7103, Standard of Care - Cystinuria | Phase 2 / Phase 3 | Withdrawn | Advicenne Pharma | 2024-05-01 | 2024-03-12 | |
| Exploratory Study on the Treatment of Gout With Potassium Citrate Sustained-release Tablets Sodium Bicarbonate Oral Capsule, Potassium Citrate Tablets, uric-acid-lowering drug - Hyperuricemia or Gout, Nephrolithiasis | Phase 4 | Recruiting | Huashan Hospital | 312 | 2024-04-10 | 2025-05-13 |
| Hydroxycitrate: A Novel Therapy for Calcium Phosphate Urinary Stones OHCit- standard dose, Potassium Citrate, Placebo - Calcium Phosphate Kidney Stones | Phase 4 | Recruiting | University of Texas Southwestern Medical Center | 25 | 2023-12-13 | 2026-06-02 |
| Potassium Citrate and Crystal Light Lemonade Potassium citrate, Crystal light, Potassium citrate + crystal light - Kidney Stone | Not applicable | Active not recruiting | Northwestern University | 10 | 2022-08-01 | 2026-01-21 |
| Study Evaluating Subjects With Distal Renal Tubular Acidosis ADV7103, Placebo - Distal Renal Tubular Acidosis | Phase 3 | Terminated | Advicenne Pharma | 3 | 2021-09-20 | 2026-06-03 |
| Dietary Counseling or Potassium Supplement to Increase Potassium Intake in Patients With High Blood Pressure Dietary Counselling, Potassium Citrate - Hypertension | Phase 3 | Completed | Ottawa Hospital Research Institute | 7 | 2019-12-01 | 2025-04-09 |
| Comparative Clinical Evaluation of Three Different Agents in Reducing Dental Hypersensitivity in Periodontal Patients Sensodyne Repair and Protect, Dentalclean Daily Regenerator, Dentalclean Daily Regenerator with potassium citrate - Dentin Hypersensitivity, Periodontal Diseases | Phase 4 | Completed | University of Sao Paulo | 33 | 2019-07-29 | 2023-11-28 |
| A Dietary Source of Potassium Citrate to Resolve Hypocitraturia and Aciduria in Patients With Kidney Stones Kroger low calorie orange juice beverage - Kidney Calculi | Not applicable | Completed | Indiana University | 22 | 2019-06-01 | 2020-11-19 |
| The Efficacy and Safety of Ilaprazole/Doxycycline-based Bismuth-containing Quadruple Therapy on Hp Infected Duodenal Ulcers Doxycycline Hyclate Enteric-Coated Capsules, Amoxicillin Capsules, Ilaprazole Enteric-Coated Tablets - Duodenal Ulcer Due to Helicobacter Pylori | Phase 4 | Completed | The Third Xiangya Hospital of Central South University | 184 | 2017-12-13 | 2022-03-02 |
| Effect of Dietary Sodium and Potassium Citrate on Renal Mineral Handling Sodium and Potassium Citrate, Placebo - Kidney Stone | Not applicable | Terminated | University of Chicago | 30 | 2017-10-01 | 2025-04-22 |
| Potassium Supplementation in CKD Potassium Chloride, Potassium Citrate, Placebo - Renal Insufficiency, Chronic, Potassium Depletion | Not applicable | Active not recruiting | Erasmus Medical Center | 532 | 2017-07-01 | 2026-08-10 |
| Efficacy of Potassium Citrate in the Treatment of Postmenopausal Osteopenia Potassium citrate, Placebo, Vitamin D3 - Osteopenia, Bone Disease, Metabolic | Not applicable | Completed | Istituto Ortopedico Rizzoli | 40 | 2015-09-01 | 2019-11-12 |
| Effect of Urine Alkalinazation on Urinary Inflammatory Markers in Patients With Cystinuria Potassium citrate - Cystinuria, Renal Lithiasis | Completed | European Georges Pompidou Hospital | 63 | 2015-04-02 | 2022-03-22 | |
| The Predictors of Successful Oral Dissolution Therapy in Radiolucent Renal Stones; A Prospective Evaluation Oral alkalinization (Potassium citrate, Allopurinol), Life style modification, Dietary recommendations (decrease purine rich diet as red meat and fish, increase vegetables) - Urolithiasis, Renal Stones | Phase 4 | Completed | Mansoura University | 182 | 2015-02-01 | 2018-03-22 |
Showing 20 of 28. Sign in to see all of them.
Kidney Calculi (8) · Nephrolithiasis (6) · Urolithiasis (5) · Acidosis (3) · Bone Diseases, Metabolic (3) · Hypercalciuria (3) · Hypertension (3) · Acidosis, Renal Tubular (2) · Cystinuria (2) · Osteoporosis (2) · Renal Insufficiency, Chronic (2) · Bone Diseases (1) · Calculi (1) · Dentin Sensitivity (1) · Duodenal Ulcer (1)
University of Texas Southwestern Medical Center (3) · Advicenne Pharma (2) · Albert Einstein College of Medicine (1) · Assiut University (1) · Children's Mercy Hospital Kansas City (1) · Erasmus Medical Center (1) · European Georges Pompidou Hospital (1) · Huashan Hospital (1) · Indiana University (1) · Istituto Ortopedico Rizzoli (1) · Juan A. Arnaiz (1) · Kantonsspital Baselland Bruderholz (1) · Mansoura University (1) · National Center for Research Resources (NCRR) (1) · Northwestern University (1)
United States (13) · Canada (3) · Egypt (3) · China (2) · France (2) · Switzerland (2) · Belgium (1) · Brazil (1) · Iceland (1) · Italy (1) · Netherlands (1) · Spain (1)
Ahmed A. Shokeir, MD (1) · Amr Darwish, Lecturer (1) · Ari Auron, MD (1) · Charles Y. C. Pak (1) · Deborah Sellmeyer, MD (1) · Ewout J Hoorn, MD, PhD (1) · Francisco Botet Mussons, MD (1) · Kimberly Reidy, MD (1) · Kymora B Scotland, MD, PhD (1) · Laurence Greenbaum, MD, Ph.D. (1) · Mariana S Ragghianti Zangrando, Prof (1) · Naim M Maalouf, MD (1)
PMID 22773591, PMID 25365230, PMID 25717071, PMID 30213095, PMID 35164833, PMID 35609996, PMID 39665575, PMID 40779318, PMID 42729157
2023 (1), R01DK131811 (1), R21DK097476 (1)